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1 
A RANDOMİZED CONTROLLED TRİAL: 
POVİDONE IODİNE, CHLORHEXİDİNE OR 
WATER FOR PERİURETHRAL CLEANİNG 
BEFORE URİNARY CATHETERİZATİON IN 
PEDİATRİC INTENSİVE CARE 
*Dr. Duygu Sönmez Düzkaya, **Yrd. Doç. Dr. Gülzade Uysal, *Hem. Tülay Yakut, ***Prof. Dr. Agop Çıtak 
*Istanbul University, Istanbul Faculty of Medicine, Directorate of Nursing Services, Turkey 
**Okan University School of HealthSciences, Turkey 
***Istanbul University, Istanbul Faculty of Medicine, Pediatric Intensive Care Unit, Turkey
2 
AAİİMM 
• The aim of the research was to evaluate the effects of 
periurethral cleaning with 10% povidone-iodine, 
0.05% chlorhexidine or sterile water in preventing 
catheter-associated urinary tract infections (CAUTIs) 
prior to insertion of urinary a catheter in a pediatric 
intensive care unit setting.
3 
METHOD 
The research was conducted as a randomized controlled 
experimental research in a pediatric intensive care unit of a 
university hospital between September 2012, and December 
2013, after obtaining necessary permissions.
4 
METHOD 
• Patients who were admitted into hospital between the specified 
dates and met the sample selection criteria were separated into 
three randomized controlled groups. 
• Each group comprised 50 children. During the research process, 
28 patients (povidone-iodine=10; chlorhexidine=8; sterile 
water=10) whose were not meet the criteria for follow-up were 
excluded of research. 
• The research was completed with 112222 cchhiillddrreenn..
5 
METHOD 
Başlangıç Örnekle 
m 
dışında 
kalanlar 
Bitiş 
PPoovviiddoonn iiyyoodd 50 10 40 
KKlloorrhheekkssiiddiinn 50 8 42 
SStteerriill ssuu 50 10 40 
TTOOPPLLAAMM 150 28 112222
6 
METHOD 
• The research was processed in three phases. 
• In the first phase, nurses who worked in clinic were informed 
about preventing catheter-associated urinary tract infections 
(CAUTIs) and were requested to provide patient care in line with the 
prepared handbook. 
• For the second phase, consent was given by the patients’ family 
and the patients were separated into three groups. 
• In the third phase, the patients were tracked by making 
periurethral cleaning pursuant to their group, which was identified 
according to the urinary system catheter put on/put out handbook
7 
METHOD 
• Urine culture were included in the first 24 hours 
after the patient's admission to the intensive care 
unit. Then following a culture taken every 3 days 
was sent to the laboratory in appropriate conditions
8 
METHOD 
• Data were obtained using Patient Identifying Form and Daily 
Observation Form. 
• Data were evaluated using appropriate statistical methods with the 
SPSS 17.0 Program.
9 
RREESSUULLTT 
• The median the age of the children was twelve months (mean=43.01± 
56.92 months); 51.6% were boys. 
• Of the patient group, 32.8% had been admitted for respiratory 
illnesses; and 21.3% had neurologic disease.
10 
RREESSUULLTTSS 
n % ÜREME 
PPoovviiddoonn 
iiyyoodd 
6 15 3 candida albicans 
3 klebsiella 
KKlloorrhheekkssii 
ddiinn 
2 4.8 2 candida albicans 
SStteerriill ssuu 3 7.5 2 e.coli 
1 vre 
• CAUTIs TTOOTTAALL occurred in 5 patients from the 5 povidone candida albicans, iodine group 3 klebsiella 
(12.5%), 2 
patients (4.8%) in the chlorhexidine 11 27.3 group, 2 e.coli, and 1 3 vre 
patient (%7.5%) in the 
sterile SF group. 
• Although more patients in the povidone iodine group had CAUTIs, no 
statistical difference was found between the three groups (p>0.05).
11 
RREESSUULLTTSS 
Catheter care 
product 
The duration of intensive 
care 
Duration of stay on 
mechanical ventilation 
The duration of the 
catheter 
(p>0, 05)
12 
CCOONNCCLLUUSSIIOONN 
• Chlorhexidine reduce the rates of CAUTIs in pediatric 
intensive care. 
• Although these results were not statistically significant, 
they are clinically important.
13

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Salon 2 14 kasim 15.30 17.00 duygu sönmez düzkaya-ing 2

  • 1. 1 A RANDOMİZED CONTROLLED TRİAL: POVİDONE IODİNE, CHLORHEXİDİNE OR WATER FOR PERİURETHRAL CLEANİNG BEFORE URİNARY CATHETERİZATİON IN PEDİATRİC INTENSİVE CARE *Dr. Duygu Sönmez Düzkaya, **Yrd. Doç. Dr. Gülzade Uysal, *Hem. Tülay Yakut, ***Prof. Dr. Agop Çıtak *Istanbul University, Istanbul Faculty of Medicine, Directorate of Nursing Services, Turkey **Okan University School of HealthSciences, Turkey ***Istanbul University, Istanbul Faculty of Medicine, Pediatric Intensive Care Unit, Turkey
  • 2. 2 AAİİMM • The aim of the research was to evaluate the effects of periurethral cleaning with 10% povidone-iodine, 0.05% chlorhexidine or sterile water in preventing catheter-associated urinary tract infections (CAUTIs) prior to insertion of urinary a catheter in a pediatric intensive care unit setting.
  • 3. 3 METHOD The research was conducted as a randomized controlled experimental research in a pediatric intensive care unit of a university hospital between September 2012, and December 2013, after obtaining necessary permissions.
  • 4. 4 METHOD • Patients who were admitted into hospital between the specified dates and met the sample selection criteria were separated into three randomized controlled groups. • Each group comprised 50 children. During the research process, 28 patients (povidone-iodine=10; chlorhexidine=8; sterile water=10) whose were not meet the criteria for follow-up were excluded of research. • The research was completed with 112222 cchhiillddrreenn..
  • 5. 5 METHOD Başlangıç Örnekle m dışında kalanlar Bitiş PPoovviiddoonn iiyyoodd 50 10 40 KKlloorrhheekkssiiddiinn 50 8 42 SStteerriill ssuu 50 10 40 TTOOPPLLAAMM 150 28 112222
  • 6. 6 METHOD • The research was processed in three phases. • In the first phase, nurses who worked in clinic were informed about preventing catheter-associated urinary tract infections (CAUTIs) and were requested to provide patient care in line with the prepared handbook. • For the second phase, consent was given by the patients’ family and the patients were separated into three groups. • In the third phase, the patients were tracked by making periurethral cleaning pursuant to their group, which was identified according to the urinary system catheter put on/put out handbook
  • 7. 7 METHOD • Urine culture were included in the first 24 hours after the patient's admission to the intensive care unit. Then following a culture taken every 3 days was sent to the laboratory in appropriate conditions
  • 8. 8 METHOD • Data were obtained using Patient Identifying Form and Daily Observation Form. • Data were evaluated using appropriate statistical methods with the SPSS 17.0 Program.
  • 9. 9 RREESSUULLTT • The median the age of the children was twelve months (mean=43.01± 56.92 months); 51.6% were boys. • Of the patient group, 32.8% had been admitted for respiratory illnesses; and 21.3% had neurologic disease.
  • 10. 10 RREESSUULLTTSS n % ÜREME PPoovviiddoonn iiyyoodd 6 15 3 candida albicans 3 klebsiella KKlloorrhheekkssii ddiinn 2 4.8 2 candida albicans SStteerriill ssuu 3 7.5 2 e.coli 1 vre • CAUTIs TTOOTTAALL occurred in 5 patients from the 5 povidone candida albicans, iodine group 3 klebsiella (12.5%), 2 patients (4.8%) in the chlorhexidine 11 27.3 group, 2 e.coli, and 1 3 vre patient (%7.5%) in the sterile SF group. • Although more patients in the povidone iodine group had CAUTIs, no statistical difference was found between the three groups (p>0.05).
  • 11. 11 RREESSUULLTTSS Catheter care product The duration of intensive care Duration of stay on mechanical ventilation The duration of the catheter (p>0, 05)
  • 12. 12 CCOONNCCLLUUSSIIOONN • Chlorhexidine reduce the rates of CAUTIs in pediatric intensive care. • Although these results were not statistically significant, they are clinically important.
  • 13. 13