1) Rocky Mountain spotted fever (RMSF) is a reemerging infectious disease in Arizona and Sonora transmitted by ticks that can cause serious complications and death if not properly diagnosed and treated with doxycycline within 5 days.
2) RMSF disproportionately impacts vulnerable groups like children, indigenous populations, migrants, and those in poverty who have less access to healthcare and live in environments conducive to tick habitat.
3) Public health interventions are needed to address both medical and socio-environmental factors contributing to RMSF in the region, including improving clinician awareness and diagnosis, reducing tick habitat in homes, and supporting at-risk communities.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
2. unit no iii dynamic of disease, Community Health NursingSANJAY SIR
it is uploaded to help medics, paramedics and nursing educators to teach their students about dynamic of disease. it also help to create awareness in general people about it.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
2. unit no iii dynamic of disease, Community Health NursingSANJAY SIR
it is uploaded to help medics, paramedics and nursing educators to teach their students about dynamic of disease. it also help to create awareness in general people about it.
Epidemiology is the study and analysis of the patterns, causes, and effects of health and disease conditions in defined populations. It is the cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences
Epidemiology, Triad of epidemiology, Brief epidemiology, Terminology used in Epidemiology, Epidemiology, traid, modes of disease transmission, disease control and prevention, Basic epidemiology, John Snow and Cholera with Epidemiology
The flesh-fly-sarcophaga-(liopygia)-crassipalpis-macquart-1839-as-an-invader-...Annex Publishers
Abstract
We present an indoor forensic case that occurred in spring 2013 in Cosenza (southern Italy). The entomological evidence collected at the scene consisted of Calliphoridae (Calliphora vicina, Lucilia sericata), Sarcophagidae (Sarcophaga crassipalpis), Fanniidae (Fannia scalaris) and Muscidae (Hydrotaea ignava). The minimum Post Mortem Interval (mPMI) was calculated by relating the entomological evidence to data available for Diptera species in the area and to our knowledge of the development of flies used as forensic indicators in Calabria. We report S. crassipalpis as a corpse invader for the first time in Italy.
Keywords: Forensic case; Flies; S. crassipalpis; mPMI; Southern Italy
Abstract
Here in a systematic, accurate and reliable method, Head-Space Gas Chromatography-Mass Spectrometry (HS-GC/MS) was developed to determine blood carboxyhemoglobin (COHb%), in order to investigate deaths related to CO exposure especially involving blood and hepatic tissues. Using a column packed with molecular sieve, COHb levels were quantified down to 0.2% in small blood samples quickly and showed good reproducibility with RSD of the COHb < 1%. COHb% in hepatic samples stored at different temperatures (-20 °C for 1- 2 years, 0 °C, and 18 °C for two months) can be determined even when the samples are decomposed. The 3-min procedure requires only 0.25 mL of blood sample or 1.0 g of hepatic tissue each time. The technique has a clear advantage over other methods such as UV spectrophotometry.
Keywords: Carbon monoxide poisoning; COHb; Decomposed hepatic tissues; Headspace gas chromatography/mass spectrometry (HS-GC /MS)
Epidemiology is the study and analysis of the patterns, causes, and effects of health and disease conditions in defined populations. It is the cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences
Epidemiology, Triad of epidemiology, Brief epidemiology, Terminology used in Epidemiology, Epidemiology, traid, modes of disease transmission, disease control and prevention, Basic epidemiology, John Snow and Cholera with Epidemiology
The flesh-fly-sarcophaga-(liopygia)-crassipalpis-macquart-1839-as-an-invader-...Annex Publishers
Abstract
We present an indoor forensic case that occurred in spring 2013 in Cosenza (southern Italy). The entomological evidence collected at the scene consisted of Calliphoridae (Calliphora vicina, Lucilia sericata), Sarcophagidae (Sarcophaga crassipalpis), Fanniidae (Fannia scalaris) and Muscidae (Hydrotaea ignava). The minimum Post Mortem Interval (mPMI) was calculated by relating the entomological evidence to data available for Diptera species in the area and to our knowledge of the development of flies used as forensic indicators in Calabria. We report S. crassipalpis as a corpse invader for the first time in Italy.
Keywords: Forensic case; Flies; S. crassipalpis; mPMI; Southern Italy
Abstract
Here in a systematic, accurate and reliable method, Head-Space Gas Chromatography-Mass Spectrometry (HS-GC/MS) was developed to determine blood carboxyhemoglobin (COHb%), in order to investigate deaths related to CO exposure especially involving blood and hepatic tissues. Using a column packed with molecular sieve, COHb levels were quantified down to 0.2% in small blood samples quickly and showed good reproducibility with RSD of the COHb < 1%. COHb% in hepatic samples stored at different temperatures (-20 °C for 1- 2 years, 0 °C, and 18 °C for two months) can be determined even when the samples are decomposed. The 3-min procedure requires only 0.25 mL of blood sample or 1.0 g of hepatic tissue each time. The technique has a clear advantage over other methods such as UV spectrophotometry.
Keywords: Carbon monoxide poisoning; COHb; Decomposed hepatic tissues; Headspace gas chromatography/mass spectrometry (HS-GC /MS)
Annex Publishers, as an Open Access publication model allows the dissemination of research articles to the worldwide community. We offer you the advantage of interaction with the most effective minds from the scientific community. All articles printed under open access will be accessed by anyone.
www.annexpublishers.com
Abstract
Age estimation of unknown human cadavers is important in setting a crime investigation, such as homicide, suicide or in mass disaster because it can guide forensic investigators to the correct identity among a large number of possible matches. More and more the courts ask for medico-legal age estimations of unknown human cadavers by forensic dentistry. This research project in establishing the applicability of radiographic and morphological parameter's used in forensic dentistry in a Portuguese adult population. The main goal is to compare the chronological age with the dental age estimation by radiographic and morphological parameters. To achieve this objective, thirty-five single-rooted teeth were analysed. Radiographic analysis was made through the program of digital radiology software Kodak RVG intra-oral 2200 with exposure factors 60-70 KVp and 7mA. The morphological parameter, translucent dentin was assessed in intact and sectioned tooth. The relationship between the coefficients was calculated between the age and the ratios with the level of inclusion, p< 0.05. There was no statistically significant difference between the chronological age and the age estimation by each method. The coefficient of Pearson for the direct measurements of the translucent dentin methodology for sectioned teeth gives the better correlation with the age estimate (r=0.86).
JOURNAL OF VETERINARY SCIENCE & ANIMAL HUSBANDRYAnnex Publishers
Journal of Veterinary Science and Animal Husbandry (JVSAH) is a scientific journal which has topics associated with fundamental and aspects of veterinary science and animal husbandry. JVSAH has a special feature of publishing special issues in experimental clinical research, veterinary medicine and current research. At Annex Publishers, we tend to publish quality articles and try our best to provide the most effective analysis journal to the scientific community.
Abstract
A new method for improvement of 1,2-indandione-treated latent fingermarks on thermal paper will be described in this paper. Treatment with conventional techniques like ninhydrin in petroleum ether or DFO solution produces a black color on the thermosensitive side of thermal paper. The new method using 5,6-dimethoxy-1,2-indandione with polyvinyl pyrrolidone (PVP) can reduce this dark staining without removing the thermosensitive layer and parts of the developed fingermarks. An advantage of this method is that the developed fluorescent fingermarks appear in sharp lines and high contrast . The developed fingermarks can be observed when excited in the 535 nm region and using an orange-red goggles. There is no background coloration in this method. In addition, some tests were performed, leading to an optimized working solution, which charges the paper with a minimum of chemicals, is cheap, and enables a large quantity of papers to be treated in a short time and without involving any pre- or post treatment.
An interesting-coexistence-of-a-classical-nodular-and-an-adenoid-ulcerous-bas...Annex Publishers
Abstract
Basal cell carcinoma is the most frequent malignant tumor of the skin, and the most common carcinoma found in some countries. The main clinical subtypes of BCC are nodular, superficial, pigmented and morpheaform. The majority of the lesions appear on the head and neck, with a particular predilection on the upper central part of the face. Here we report a 62 year-old woman with two different morphological types of BCC which developed in the same area. The tumors have developed two months apart on the right paranasal region in close proximity. With the clinical examination and histopathological examination of punch biopsy specimens, the diagnoses of the lesions were confirmed as a nodular and an adenoid BCC. The tumors were totally removed with surgical excision. Neither recurrence nor new lesion was observed on the lesional or near areas in a 24-month follow-up period. To the best of our knowledge the presence of the two different morphological types of BCC in the same anatomical location has not been reported previously.
Abstract
A person's stature is an identifying characteristic that is often used in forensic investigation. Footprint is the one of the valuable physical evidence encountered in the crime scenes and examination of barefoot impressions is important especially in developing countries like India, Malaysia where majority of the rural population like to walk barefooted because of socio-economic and climatic reasons. Foot impressions are still found at crime scenes, since offenders often tend to remove their footwear either to avoid noise or to gain better grip in climbing walls, etc., while entering or exiting. Most of the foot/foot print studies were conducted on mixed population. The researchers have cautioned that the people from different races and regions of a country bear different morphological features depending upon their geographical distribution and primary racial characteristics and hence a single formula cannot represent all parts of that country or world. The present study aims to estimate stature from bilateral footprints collected from 320 (160 males, 160 females) consenting adult Ibans, an indigenous group residing in Sarawak state, east Malaysia. Informed consent and Human Ethical Approval were obtained. The height of the individuals and footprints were collected following the standard procedure. The data obtained were analyzed with PASW 20 computer software and derived regression formulae to estimate stature from footprint lengths of Iban ethnics. The result of the investigation revealed that all footprint lengths exhibit statistically positive significant correlation with stature (p< 0.001). Correlation coefficient (R) values are found to be higher in the pooled sample (0.861–0.887) when compared with males (0.753–0.789) and females (0.728–0.790). The regression formulae derived for the pooled sample can be used to estimate stature when the sex of the footprint remains unknown, as in real crime scenarios.
Journal of Biometrics and Its Applications (JBIA) is peer reviewed open access journal which addresses the fundamental areas in computer science that deal with biological measurements. It covers both the theoretical and practical aspects of human identification and verification. Biometrics based authentication, an integral component of identity science, is now being utilized in several applications playing a central role in personal, national and global security. Biometric refers to the field of development of statistical and mathematical methods applicable to data analysis problems in the biological sciences.
Tame to-torture-psychosexual-correlations-of-sex-violence-and-tortureAnnex Publishers
Abstract
This paper discusses the psychosexual correlations and psychological consequences related to torture and behavioral acts that are fundamentally torturous. The influence of participation by learning and the relationship of acts to thought and thought to acts are further discussed to raise awareness to the effects of torture on the torturer. Theories from multiple disciplines are presented in an integrated context to examine the correlation between fundamental psychological principles associated with acts that are torturous in nature and, therefore, innately evil.
Keywords: Aggression; Crime; Criminology; Behavioral acts; Human behavior; Psychological effects; Psychology; Psychopathology; Psychosexual; Sex; Sex crimes; Sexuality; Torture; Violence
Abstract
Programming scripts were written for the statistical analysis of genetic data from simple cases and complex cases of undetermined paternity. The methods presented here involve algorithms constructed with R, an open-source and increasingly popular programming language used for calculations and statistics; these methods also involve conditional probability analysis, Bayes’ Theorem, and pedigree analysis. Previous computer programs for assessing probable paternity in complex cases of undetermined paternity have been written; however, only minimal or generalized formulas are described in the papers presenting these programs. Therefore, these previously published programs are difficult to understand for most forensic researchers. Here, we present the details of the calculations used to evaluate probabilities of paternity and the details of the R scripts used execute these calculations. These scripts were constructed not only for standard trio case where DNA typing of the mother, child, and the alleged father are available, but also for more complex cases where DNA typing of the alleged father is absent. In these more complex cases, the putative genotype of the alleged father is determined from the genotypes of his parents, his siblings, his wife, children known to be his biological children, or some combination of these people. This report provides concrete and orderly descriptions of the calculations and the R scripts so that each facet of this method is easily understood. Furthermore, access to these scripts will enable individual researchers to develop calculation systems of their own.
Keywords: Forensic mathematics; Paternity testing; R; DNA typing
Case report: A 49-year-old previously healthy man was admitted to the ICU after cardiac arrest following a short history with headache, blurred speech and reduced consciousness. After cardiopulmonary resuscitation perfusion rhythm was regained, but the patient didn`t regain consciousness. The arterial blood gas analysis at the ICU revealed a severe metabolic acidosis with pH at 6.86 and lactate levels of 16 mmol/L. The white blood cells count was also markedly increased (312 * 109/L), and blood smear showed immature cells indicating acute leukemia. The severe metabolic acidosis, at first thought to be due to systemic hypoperfusion, did not improve in spite of fluid and vasopressor resuscitation. A CT scan of the head performed the next day, revealed massive cerebellar haemorrhage, edema in both hemispheres and signs of anoxic brain damage. Immunophenotyping of peripheral blood was consistent with Acute Myeloid Leukemia (AML).
Abstract
Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry. With characterization of over 2500 Salmonella serovars, the pathogen nearly infects all vertebrates but the severity of infection varies from one serovar to another depending upon their host specificity. Some Salmonella serovars are restricted to one or few hosts while others have a broad host spectrum. Thus the understanding of the mechanisms involving host preference by one serovar over another is very important. As our knowledge about host adaptability will then be instrumental in designing better vaccines. Furthermore, methods involving identification of genetic markers for host specificity will prove to be instrumental in determining virulence factors for other pathogenic bacteria that cause systemic infections.
Keywords: Host adaption; Evolution; Salmonella serovar; Horizontal gene transfer
Does physical-activity-and-sport-practice-lead-to-a-healthier-lifestyle-and-e...Annex Publishers
The prevalence of childhood obesity has been increasing rapidly and there is general consensus that good nutritional practices and physical activity should be encouraged as early as possible in life. The aim of this study was to describe and to compare the current lifestyle and dietary pattern of normal weight (NW) and overweight + obese (OW+OB) male adolescents who are physically active.
Methods: This observational and retrospective study was based on clinical records analysis of male adolescents aged 11-18 years who had undergone a medical evaluation at a Medical Sport Centre (Pavia, Italy) during 2009, and had filled in a self-administered life style questionnaire.
Results: The results showed that out of 1423 clinical records 23.0% of subjects were OW, 5.4% OB and 71.6% NW. We invited all the overweight and obese subjects to participate in the study, 308 of them (75.8%) agreed. Then we randomly enrolled an equivalent number of NW participants (n=308) in the medical evaluation at the sports center with similar characteristics as for socio-economic status, physical activity and age for a whole sample of 616 subjects. We handled them a validated lifestyle questionnaire. The questionnaire analysis was used to compare OW+OB and NW participants, as far as eating habits, sedentary activities and time spent in sports. All the subjects frequently skipped breakfast, did not consume fruit and vegetables daily and had a high soft drinks intake. Inverse correlations were found between weight and physical activity (p=0.01). Sedentary activities were preferred by about 25% and 66 % of the NW and OW+OB groups respectively. The percentage of smokers was similar within the two groups (14%).
Conclusions: Adolescents eating habits are incorrect, despite BMI and sports practice. Sports practice seems contributing to lower spare time physical inactivity, but does not improve eating habits. Public health interventions should focus on the reinforcement of leisure time physical activity, besides nutrition education and behavioral education programs in order to prevent obesity in the adulthood.
Study on-efficiency-of-protein-extractants-employed-for-human-origin-determin...Annex Publishers
Abstract
Human origin determination is an important aspect of blood grouping analysis in forensic science laboratories. In the present study, protein extractants like gel buffer, ammonia and saline employed for origin determination were evaluated and compared qualitatively and quantitatively for their role in the extraction of proteins from dried blood stained materials of human origin at regular time intervals. Qualitative and quantitative methods employing counter immunoelectrophoresis (CIE) and rocket immunoelectrophoresis (RIE) respectively were used to study the protein extraction efficiency of extractants. Ammonia, compared to gel buffer and saline extracted the proteins effectively. Maximum extraction of proteins was observed in 2-3 hours of sample. CIE demonstrated sharp precipitin bands with all samples of ammonia extractant compared to the samples of counterparts. RIE also revealed greater concentration of proteins in the ammonia extract compared to extracts of gel buffer and saline. These results provide evidence that ammonia serves as a better protein extractant for rapid determination of human blood origin.
Keywords: Forensic science; Forensic serology; Blood origin; Electrophoresis; Protein extractants; Immunoprecipitation
Anti inflammatory-and-anti-arthritic-efficacy-and-safety-of-purified-shilajit...Annex Publishers
Abstract
The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion). Serum samples collected from these dogs were examined each month for biomarkers of liver (bilirubin, ALT, and AST), kidney (BUN and creatinine) heart and muscle (creatine kinase) functions. The findings of this study revealed that dogs receiving Shilajit (Group-II) showed a significant (P< 0.05) reduction in pain from limb manipulation by day 60, and overall pain and pain after physical exertion by day 120. Maximum pain reduction, using all three criteria, was observed on day 150. Pain level remained significantly unchanged in dogs receiving the placebo. Dogs in either group showed no significant change (P>0.05) in physical parameters or serum markers, suggesting that Shilajit was well tolerated by moderately arthritic dogs. It was concluded that Shilajit significantly (P< 0.05) reduced pain in osteoarthritic dogs and markedly improved their daily life without any side effects.
Keywords: Purified Shilajit; Osteoarthritis in canine; Shilajit safety; Anti-arthritic nutraceutical
Background: Observational studies have shown that low folate status induces depression. Here we studied the effects of folic acid supplementation on depression scores of Japanese women with depression-susceptible gene polymorphisms: methylenetetrahydrofolate reductase (MTHFR), serotonin transporter (5-HTT), and dopamine D4 receptor (DRD4).
Design: This was a 16-wk randomized, double-blind, crossover study of a group of Japanese women. Forty-six women (mean age 20 years; range: 18-26) were included in the study. First it was determined if the subjects had one of the following depression-susceptible gene polymorphisms: MTHFR, 5-HTT, or DRD4. The subjects then consumed bread with or without folic acid (200 μg/d) during two 4-wk diet periods separated by an 8-wk washout period. Serum folate and serum total homocysteine (tHcy) concentrations were measured before and after each intervention. Depressive symptoms using the Center for Epidemiologic Studies Depression Scale (CES-D) were determined.
Results:In the folic acid period, serum folate concentration increased from 14.2 nmol/L (median, 25th-75th percentiles: 10.6-17.5) to 23.1 nmol/L (16.4-27.8 p < 0.001); tHcy was reduced from 6.6 µmol/L (5.6-7.5) to 5.7 µmol/L (4.8-6.6, p < 0.001) and CES-D score decreased from 10.0 (3.0-13.0) to 5.0 (2.0-10.0, p < 0.001). In the control period, these changes were either insignificant or reversed. CES-D score significantly decreased by supplementing with folic acid in subjects with depression-susceptible genotypes common among Japanese, namely homozygotes of the "S" allele of 5-HTT and the "4" allele of DRD4.
Abstract
Juvenile ossifying fibroma is an uncommon clinical entity, its aggressive local behaviour and high recurrence rate mean that it is important to make an early diagnosis, apply the appropriate treatment and, especially, follow the patient up over the long term. In the current article we report a case of juvenile ossifying fibroma-WHO type in 12yr old patient which was clinical and histopathologically challenging as it was asymptomatic and at an unusual location.
Public Health Response to Ebola Statement of Dr. FriedenDawn Dawson
House Energy and Commerce Committee Subcommittee on Oversight and Investigations Public Health Response to Ebola October 16, 2014
Statement of Dr. Thomas R. Frieden, M.D., M.P.H.
Director, Centers for Disease Control and Prevention
SOCIO-CULTURAL AND BEHAVIORAL FACTORS INFLUENCING CHILDHOOD IMMUNIZATION PR...GABRIEL JEREMIAH ORUIKOR
Abstract: Background: Immunization is one of the most cost-effective interventions with proven strategies to reach
the vulnerable populations. It is also a proven tool for controlling and eliminating life threatening infectious diseases.
It also prevents illness, disability and deaths from vaccine preventable diseases averting estimated 2-3 million deaths
each year.
Method: A descriptive survey research design was adopted, one hundred 100 nursing mothers were used for the
study. The instruments used for the study was a self-structured questionnaire. Simple random sampling technique
was used to select the sample for the study. Data collected were analysed using frequency, counts and percentage
table for demographic information.
Result: The findings of the study revealed that behaviour/attitude of healthcare workers and lack of enough
information were determinants of incomplete routine immunization, while life style, religion and belief were not
determinants of incomplete routine immunization. However, level of education, distance to health facility, life style,
religion and belief were jointly determinants of incomplete routine immunization among nursing mothers in Jericho
specialist hospital.
Conclusion: Based on the findings of the study; it is therefore recommended that State Government and
Philanthropists should assist in building more health care facilities close to the communities for easy accessibility.
Effort should be geared towards public campaign using local dialect to encourage them to complete routine
immunization. In addition, community mobilization should be strengthening especially among nursing mothers to
be fully informed about the merits of completing the routine immunization and to avert childhood morbidity and
mortality in our society.
OUTBREAK INVESTIGATION 1
OUTBREAK INVESTIGATION 2
Outbreak Investigation
Introduction
Epidemiology deals with the study of the determinants and distribution of disability or disease in the population groups (Szklo & Nieto, 2014). Epidemiology is one of the core areas in public health study and is essential for the evaluation of the efficacy of the new therapeutic and preventive modalities as well in the new organizational health care delivery patterns. I have for a long time developed a lot of interest in the area towards learning more on finding the causes of diseases and health outcomes in populations. Epidemiology views the individuals collectively, and the community is considered to be patient. The area of public health study is systematic, scientific, and data-driven in analyzing the pattern or frequency of the distributions and the risk factors or causes of specific diseases in the neighborhood, city, school, country, and global levels. Epidemiology handles various areas including environmental exposures, infectious diseases, injuries, non-infectious diseases, natural disasters and terrorism (Szklo & Nieto, 2014). Specifically, this paper explores epidemiology in addressing infectious disease, food-borne illness in the community. Also, the paper examines outbreak investigations as an intervention towards addressing the foodborne illness in the society. Further, an evaluation of the intervention and the expected results are discussed to examine or analyze the contributions of the intervention.
Foodborne Illness
Foodborne illness is any illness that results from food spoilage of the contaminated food. Food can be contaminated by the pathogenic bacteria, contaminated food, parasites, or viruses, as well as natural or chemical toxins including several species of beans, and poisonous mushrooms. In the United States, food-borne illness is estimated to impact negatively over 76 million people annually (Jones, McMillian, Scallan et al., 2007). This is translated to 5,2000 deaths, and 325,000 hospitalizations. However, the true incidence of food-borne illness is unknown. The majority of food-borne illness and most of the deaths are linked to “unknown agents” following the difficulties encountered in the diagnosis a foodborne disease. An estimated $7 billion is lost regarding productivity and medical expenses and is attributed to the most prevalent but diagnosable foodborne illnesses. Comment by Vetter-Smith, Molly J: Reference needed for this statement Comment by Vetter-Smith, Molly J: References needed for these statements
The under diagnosis in foodborne illnesses is further contributed by the majority who has the symptoms and signs of the disease but totally fail to seek medical attention. This circumstance coupled with the global and national distribution of foo.
Environmental Pollutants and Disease in American: Children: Estimates of Morbidity, Mortality, and Costs for Lead Poisoning, Asthma, Cancer, and Developmental Disabilities
Descriptive epidemiology involves critical organization, summarizing, and analyzing data with respect to health related problems and events to time, person and place. Descriptive study assists in providing information about a disease or condition, providing clues to identify a new disease or adverse health effect, identifying the extent of the public health problem, obtaining a description of the public health problem that can be easily communicated, identifying the population at greatest risk, assisting in planning and resource allocation, and identifying avenues for future research that can provide insights about an etiologic relationship between an exposure and health outcome (Merrill, 2013, p.88).
1. Identifying the extent of the public health problem
With respect to time, diseases rates occur over time and hence descriptive epidemiology results to prediction of an occurrence of a disease with time e.g. influenza data analysis shows it is common with cold weather. Such analysis easily contributes to identifying the causes and actions of prevention of a particular diseases occurrence with respect to a epidemiology period. It also results to critical studies of the patterns and characteristics of a disease with seasonal distribution and pattern to chronic diseases hence creation of long term changes to public health problems (Merrill, 2013, p.120).
Studying the health risks of a place results to gaining insight into the geographical extent of a health problem, risk of acquiring such a related geographical disease, the agent of infection, modes of transmission and spread and factors in the area favoring the survival of the agent of infection and in turn identifying the extent of the area public health problem translating to coming up with favorable measures of prevention e.g. malaria infection is prone to areas with hot humid climatic conditions
By organizing similar characteristics of age, gender, inheritance, human activities and their condition of living, descriptive epidemiology determines the persons or group of people who are prone to great risk of a disease infection and susceptibility to death. It enables determination of the incubation period of a particular microbial agent and the modes of transmission from a person to another. For example, it is conclusive that male are generally at a high risks to certain disease infection compared to females because of the differences in genetic, hormonal, inherited genes and other anatomical differences (Merrill, 2013, pp.120-121).
2. Describing the public health problem in a way that can be easily communicated
It enables a public health worker to have technical information more clearly, concisely and at most accurate with respect to the descriptive epidemiology of a disease studied. Hence measures of patterns and trends description of disease and health related problems can be easily communicated as familiarity with the epidemiology allows for effective description and justification in a clear.
On July 1, 1665, the lordmayor and aldermen of thecity of Lo.docxvannagoforth
On July 1, 1665, the lordmayor and aldermen of the
city of London put into place a set
of orders “concerning the infec-
tion of the plague,” which was
then sweeping through the popula-
tion. He intended that these
actions would be “very expedient
for preventing and avoiding of
infection of sickness” (1).
At that time, London faced a
public health crisis, with an inade-
quate scientific base in that the
role of rats and their fleas in dis-
ease transmission was unknown.
Nonetheless, this crisis was faced
with good intentions by the top
medical and political figures of
the community.
Daniel Defoe made an observation that could apply to
many public health interventions then and today, “This
shutting up of houses was at first counted a very cruel and
unchristian method… but it was a public good that justi-
fied a private mischief” (1). Then, just as today, a complex
relationship existed between the science of public health
and the practice of public health and politics. We address
the relationship between science, public health, and poli-
tics, with a particular emphasis on infectious diseases.
Science, public health, and politics are not only com-
patible, but all three are necessary to improve the public’s
health. The progress of each area of public health is relat-
ed to the strength of the other areas. The effect of politics
in public health becomes dangerous when policy is dictat-
ed by ideology. Policy is also threatened when it is solely
determined by science, devoid of considerations of social
condition, culture, economics, and public will.
When using the word “politics,” we refer not simply to
partisan politics but to the broader set of policies and sys-
tems. Although ideology is used in many different ways, in
this case, it refers to individual systems of belief that may
color a person’s attitudes and actions and that are not nec-
essarily based on scientific evidence (2).
Public Health Achievements
Science influences public health decisions and conclu-
sions, and politics delivers its programs and messages.
This pattern is obvious in many of public health’s greatest
triumphs of the 20th century, 10 of which were chronicled
in 1999 by the Centers for Disease Control and Prevention
(CDC) as great public health achievements, and several of
which are presented below as examples of policy affecting
successes (3). These achievements remind us of what can
be accomplished when innovation, persistence, and luck
converge, along with political will and public policy.
Vaccination
Childhood vaccinations have largely eliminated once-
common, terrible diseases, such as polio, diphtheria,
measles, mumps, and pertussis (4). Polio is being eradicat-
ed worldwide. The current collaboration between the
World Health Organization, the United Nations Children’s
Fund, CDC, and Rotary International is a political as well
as biological “tour de force,” and eradication of polio in
Nigeria has been threatened by local political struggles and
decisions. ...
Similar to Rocky mountain-spotted-fever-a-reemerging-disease-in-arizona-and-sonora (20)
Journal of Nutrition and Health Sciences is an open access journal that publishes peer reviewed research articles and short communications in all aspects of nutrition. This Journal encompasses the full spectrum of nutritional science including nutritional requirements, public health nutrition, epidemiology, dietary surveys, body composition, energetics, appetite, obesity, ageing and metabolic studies.
Journal of Proteomics & Geneomics (JPG) is an instructional journal providing a chance to researchers and scientists to explore the advanced and latest research developments within the field of Proteomics and Geneomics. Journal of Proteomics & Geneomics publishes the best quality scientific articles amalgamating broad vary of fields together with the fields associated with Proteomics & Geneomics.
Journal of Obesity and Overweight (JOO) is a peer reviewed open access journal. It is dedicated to increase knowledge, fostering research, and promoting better treatment for people with obesity. It includes subjects like nutrition medicine, clinical nutrition medicine, genetics and nutrition, biophysics and lipid metabolism, etc. It aims to publish advanced research works related to public health and medical developments.
Journal of Computational Systems Biology (JCSB) is an open access online journal which aims to publish peer reviewed research articles and short communications in all aspects of computational biology and bioinformatics. JCSB comprehend the broad spectrum of computational bioscience including biological databases and bioalgorithms.
Journal of Gynecology Research (JGR) publishes original articles and research studies on, scientific advances, new medical and surgical techniques, obstetric management, and clinical evaluation of drugs and instruments and all aspects of gynecology including gynecological endoscopy, infertility, oncology contraception, urogynecology, fertility, and clinical practice and ultrasonography. It aims to publish the highest quality medical research in women's health, worldwide.
CLINICAL AND EXPERIMENTAL RESEARCH IN CARDIOLOGYAnnex Publishers
Journal of Clinical and Experimental Research in Cardiology (JCERC) is an international open access, scholarly peer-reviewed journal publishing high quality articles in all areas of cardiology related fields, especially current research, new concepts, novel methods, new therapeutic agents, and approaches for early detection and prevention of cardiac disorders and reporting new methods on basic and advanced clinical aspects of cardiology research.
Journal of Genetic Mutations and Disorders (JGMD) is an open access, peer reviewed journal which provides advanced researches including Genetics of Infectious Diseases, Genealogical Tracing, Stem Cell Research, Gene mapping with three-point crosses, Genetic linkage and genetic maps. JGMD publishes original research, review articles in all aspects of genetic mutations and disorders
CLINICAL AND EXPERIMENTAL RESEARCH IN CARDIOLOGYAnnex Publishers
Journal of Clinical and Experimental Research in Cardiology (JCERC) is an international open access, scholarly peer-reviewed journal publishing high quality articles in all areas of cardiology related fields, especially current research, new concepts, novel methods, new therapeutic agents, and approaches for early detection and prevention of cardiac disorders and reporting new methods on basic and advanced clinical aspects of cardiology research.
Journal of Bioequivalence Studies (JBS) is an open access, peer reviewed journal that publishes the most relevant and reliable researches with respect to the subject of Bioequivalence studies which includes pharmacokinetic and pharmcodynamic properties of a drug. JBS publishes original articles, review articles, case reports, short communications, etc.
Journal of Forensic Science & Criminology (JFSC) is an open access, significant and reliable source of contemporary knowledge on advancements in the field of forensic science. JFSC publishes peer reviewed research articles, critical reviews and short communications focused on forensic science and criminology. JFSC encompasses the full spectrum of forensic science including forensic biology, forensic chemistry, cyber forensics and crime scene investigation
Anti arthritic-efficacy-and-safety-of-crominex-3+(trivalent-chromium-phyllant...Annex Publishers
Abstract
The present investigation was undertaken to evaluate the therapeutic efficacy and safety of Crominex® 3+ (a complex of trivalent chromium, Phyllanthus emblica (Amla) extract and purified Shilajit) in moderately arthritic dogs. Eleven client-owned moderately arthritic dogs in a randomized double-blinded study received placebo or Crominex® 3+ twice daily for a period of 150 days. On a monthly basis, each dog was evaluated for arthritis associated pain (overall pain, pain upon limb manipulation and pain after physical exertion) and a full physical exam (body weight, body temperature and heart rate). At the same time intervals, dogs serum samples were examined for biomarkers of kidney (BUN and creatinine), liver (bilirubin, ALT and AST) and heart and skeletal muscle (CK) functions. Findings of this investigation revealed that dogs receiving Crominex® 3+ (1000 μg chromium, 15 mg Amla extract and 15 mg purified Shilajit per day in two divided doses) exhibited a significant (P< 0.05) reduction in arthritic pain noted as early as after 90 days with a maximum reduction after 150 days of treatment. Pain level remained the same or slightly increased in the dogs receiving placebo. No significant change occurred in physical parameters or serum biomarkers in dogs on placebo or Crominex® 3+, which suggested that Crominex® 3+ was well tolerated by arthritic dogs. In conclusion, Crominex® 3+ significantly (P< 0.05) ameliorated arthritic pain and improved quality of life without causing any untoward effects in moderately arthritic dogs.
Abstract
The objectives of this retrospective study were 1. To determine the effect of three surgical techniques (right flank omentopexy, right flank omentoabomasopexy, and left flank abomasopexy), and 2. To determine the effect of concurrent disease on return to normal milk production. Return to normal milk production occurred in 86.3% of cows diagnosed with LDA. Results suggested that cattle diagnosed with LDA corrected via right flank omentopexy or left flank abomasopexy were significantly more likely to return to normal milk production as compared to those corrected via right flank omentoabomasopexy (p< 0.02). No significant difference in return to normal milk production was noted between surgical techniques for correction of RDA (p=1.000) and right abomasal volvulus (p=0.596). Concurrent disease diagnoses did not affect return to milk production. Reported complications were infrequent (n=11).
List of abbreviations: LDA- Left displaced abomasum; RDA- Right displaced abomasum; RAV- Right abomasal volvulus; RAOV- Right abomasal-omasal volvulus; RFO- Right flank omentopexy; RFOA- Right flank omentoabomasopexy; LFA- Left flank abomasopexy; DA – Displaced Abomasum
Abstract
Three surgical case reports are presented to demonstrate the clinical efficacy of using an improved aqueous solution of chlorine dioxide complex (160 ppm) as a topical antiseptic in the post operative management of serious wounds in dogs. In vitro studies are included to demonstrate the antiseptic properties of this new chlorine dioxide complex.
Keywords: Chlorine dioxide; Antiseptic; Antimicrobial; Wound management
Abbreviations: ClO2-Chlorine dioxide; Cl2-Chlorine; PPM-Parts Per Million; SPP-Species; TEM-Transmission Electron Micrograph
The updated-international-veterinary-anatomical-and-embryological-nomenclaturesAnnex Publishers
The international nomenclature of the anatomical, histological and embryological terms is known as Nomina Anatomica Veterinaria (N.A.V.), Nomina Histologica Veterinaria (N.H.V.) and Nomina Embryologica Veterinaria (N.E.V.).
This is the tripod of terms for the morphological sciences in our profession, a dictionary of terms used by all specialists in the basic and in the clinical sciences.
The discovery of the presence of stem cells and precursors with high regenerative potential in the mammary gland, hypothetically maintained throughout the course of the productive life of the dairy cow sheds an interesting perspective in the research which is interested to clarify all physiological clues and possible solutions to increase or maintain longer the potential production of dairy cows during life span of lactation. In 2006, Connie Eaves' lab in Vancouver (Stingl et ., 2006) [1]
Abstract
Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases. In skeletal muscle, it plays an essential role in muscle fiber specialization, muscle mass maintenance, damage induced muscle regeneration and muscle diseases. This review provides an overview of MAPK pathway and its pathophysiological role in skeletal muscle diseases with a primary focus on muscular dystrophy and atrophy.
Abstract
An examination experiment has been carried out to investigate whether fingerprint powder and lifting technique can recover and transfer latent fingerprints from human skin surfaces of dead bodies. For recovery Swedish Black powder and for transfer White Fingerprint Gelatine were used.
Donors placed fingerprints on the human skin surfaces. Finger marks were then in all cases recovered with Swedish Black powder. The procedure was repeated after 2, 3, 4 and 5 hours. Treated finger marks were secured and preserved as latent fingerprint evidence by lifting process. We recovered 8% finger marks suitable for further examination of all deposited samples on the human skin surfaces.
The fatal-alcoholic ketoacidosis-as-a-dilemma-in-the-differential-diagnosis-i...Annex Publishers
48-years old man was found dead at home, lying in his bed. There was a bucket with liquid vomited remnants with no addition of fresh or digested blood found near the bed and an empty bottle of alkaline mineral water often used to attenuate the gastric pain. Up to the information from the man's relative, he was a chronic alcohol consumer, being last seen alive the day before in the pub, drinking small amount of beer. His personal anamnesis was negative for the previous injuries or any pathological entity which could have potential fatal outcome. External observation of the body did not uncover any signs of mechanical violence on the body. The only pathological findings at the autopsy were: very mild generalised atherosclerosis without stenosis of blood vessels, configuration of the heart with the weight of 400 g was physiological, with no signs of chronic venostatic changes on the internal organs.
Journal of Forensic Science & Criminology (JFSC) is an open access, significant and reliable source of contemporary knowledge on advancements in the field of forensic science. JFSC publishes peer reviewed research articles, critical reviews and short communications focused on forensic science and criminology. JFSC encompasses the full spectrum of forensic science including forensic biology, forensic chemistry, cyber forensics and crime scene investigation
Abstract
The synthetic cannabinoid, N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide, known also as AKB48 and/or APINACA, has been detected for the first time in herbal incense seized in Italy. Its structural characterization has been performed through gas chromatography-mass spectrometry (GC-MS) and high-resolution nuclear magnetic resonance (NMR) analysis. In order to favor an easier and faster identification of AKB48 in future investigations, NMR assignments in deuterated methanol and chloroform is also reported.
Keywords: NMR; GC-MS; Designer drug; Synthetic cannabinoid; Herbal incense
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
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Volume 1 | Issue 6
Rocky Mountain Spotted Fever, A Reemerging Disease in Arizona and Sonora- Case Study
Alvarez G*1, Rosales C2 and Sepulveda R3
1Department of Medicine and Health Sciences, University of Sonora, Hermosillo Sonora, Mexico
2Community, Environment, and Policy Division, The University of Arizona, Mel and Enid Zuckerman College of Public Health, Tucson, Arizona
3Public Health Doctoral Student, Community, Environment, and Policy Division, The University of Arizona, Mel and Enid Zuckerman College of Public Health, Tucson, Arizona
*Corresponding author: Alvarez G, Department of Medicine and Health Sciences, Universidad de Sonora. Hermosillo, Sonora, Mexico, E-mail: galvarezh63@gmail.com
Case Report
Open Access
Citation: Alvarez G, Rosales C, Sepulveda R (2014) Rocky Mountain Spotted Fever, a Reemerging Disease in Arizona and Sonora - Case Study. J Case Rep Stud 1(6): 601. doi: 10.15744/2348-9820.1.601Abstract
Rocky Mountain spotted fever, Rickettsia Rickettsii (RMSF) is a reoccurring disease in Arizona and Sonora and a public health problem due to the high risk medical complications it provokes. In the region it is transmitted by the bite of the Rhipicephalus sanguineus tick, found in dogs. This tick transmits Rickettsia rickettsii bacteria. Following an incubation period of 3-14 days, it causes acute, non-specific effects early on (fever, headache and rash) that -if not diagnosed and treated in time can be serious or cause death. Death is primarily associated with two factors: (a) delay in diagnosis, and (b) doxycycline, a highly effective antibiotic treatment which is inexpensive and simple to administer is delayed. If doxycycline is not provided before the 5th day after the symptoms begin, the patient can worsen and present with dark purple spots on the body, mostly hands and soles, wrists and ankles as well as have heart, hepatitis, renal, central nervous symptoms and other multiple organ complications. RMSF should be considered a medical priority and a public health problem at the regional level with a network of underlying factors. To prevent and control RMSF in Arizona and Sonora, public health interventions will need to address medical challenges associated with a number of social, political, and environmental factors. Introduction
Since reemerging in Sonora in early 2000, there has been an average of 100 cases of per year of RMSF, with epidemic outbreaks and scattered clusters. The disease has spawned from the southern part of the state and today has extended to border towns along the Arizona-Sonora region such as Nogales and Agua Prieta, affecting rural as well as urban areas. Although RMSF can happen at any age, it is particularly serious in children younger than 10 years of age [1-2]. The gravity observed in the general population in Sonora ranges between 8 and 10%, yet in children it increases to 30% [3] which is considerably higher to that reported (2-3%) in endemic areas from the United States [4]. In the Sonoran Children’s Hospital (HIES-Hospital Infantil Estatal de Sonora) between 2004-2012, 125 children have been treated for RMSF from 34 locations throughout the state, of which 37 have died, with a fatality rate of 29.6% [3]. An uprising trend in morbidity and mortality of the disease has been previously reported in this population from Sonora [5], meanwhile in tribal lands of Arizona incidence (17.2 per 1,000,000) is higher than for the general population [6]. Conditions of poverty, lack of access to health services, and cultural patterns associated with migration contribute to health challenges and probably increase the risk and vulnerability of people who settle in communities made up mainly of migrants from the more southern states in Mexico.
RMSF should be considered a medical priority and a public health problem at the regional level with a network of underlying factors which merit specific interventions. In our opinion, for Arizona and Sonora the main interventions include the following:
a) Medical Challenges: There is sufficient scholarly literature and practice to understand that the mortality and complications produced by RMSF can be considerably reduced or avoided if the initial medical provider suspects the diagnosis and initiates opportune treatment with doxycycline [7-9]. From the HIES experience, 9 out of every 10 children with RMSF had at least one doctor’s visit before hospitalization was necessary, and the disease was not suspected early by clinicians, who prescribed antibiotics for other illnesses that mimic the disease, which has been related to fatal outcomes [10]. It is also known that there is a general lack of awareness in the medical and public health community about the epidemiology of the disease [11]. This may contribute to delayed therapy and a lack of knowledge and awareness by the community on how to identify the illness and take preventive measures. This may increase risk of infection for vulnerable populations (i.e. children, native groups, migrants) living in rural settings and in impoverished conditions [1,12].
Volume 1 | Issue 6
Journal of Case Reports and Studies
ISSN: 2348-9820
Received Date: April 22, 2014 Accepted Date: June 17, 2014 Published Date: June 20, 2014
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Volume 1 | Issue 6
Journal of Case Reports and Studies
2Conclusion
b) Socio-environmental conditions: Although RMSF has long been attributed to contact with domestic dogs [7,13], it is basic to understand that only a small proportion of the tick population lives temporarily on domestic pets and is more commonly found in the soil, between cracks in walls, housing foundations, and other items (i.e. unused furniture in the yard) [14,15]. In fact, dogs may constitute a barrier to mitigate the attacks on humans by ticks, as these ectoparasites tend to be attracted to dogs by warmth, physical contact and odors. Therefore, strategies to eliminate dogs do not solve the problem. What does help is to protect children from ticks through household interventions using safe but effective pesticides, actions such as eliminating unused furniture and other environmental measures [15]. In Sonora and Arizona, social conditions, in addition to climate in the region, may increase the vector density and lessen the factors that can reduce the risk of RMSF (i.e. low education, lack of resources to guarantee pet care). Children are especially vulnerable because they tend to spend long periods of time playing around spaces where ticks survive or because adults do not routinely check children for exposure to ticks [1,7]. Finally, global warming can produce more aggressive attacks on humans [16].
Rocky Mountain spotted fever is a public health problem due to the magnitude and impact at a population level. If not timely diagnosed, health outcomes resulting from RMSF may range from a simple fever and headache to death. Cases resulting in death are primarily associated with two factors: 1) lack of clinical suspicion and 2) a delay in the administration of doxycycline, a highly effective antibiotic treatment that is inexpensive and simple to administer. If doxycycline is not administered to a patient within the first five days after he or she begins having RMSF symptoms, then they may develop heart, renal, and multiple organ complications which can lead to death. RMSF should be considered a major medical priority and a serious public health problem at the regional level with a net of underlying factors. Public health interventions to prevent and control RMSF in Arizona and Sonora will need to focus on a number of medical challenges associated with the social, political, and environmental conditions of the target region.
c) Socio-political factors: Indigenous groups are vulnerable because they have fewer resources to deal with RMSF. In HIES, one out of four hospitalized patients belong to indigenous migrant communities, and they had the highest fatality rate (40.6%) for the 2004-2012 period. Moreover, in Sonora, indigenous people are recruited or migrate from southern states in Mexico to work in the agricultural industry. They migrate or agree to the long journey to work in northern Mexico due to their social disadvantage [17]. Limited funding of public health programs may result in few if any prevention and control programs to address this reemerging disease. In the U.S., tribal lands are considered sovereign; therefore, local, state and federal government programs in Arizona and the U.S. can only advise public health authorities on Tribal Lands. Although there are government efforts for this type of population, there is no federal, state or local program well financed or culturally appropriate and socially accepted, designed to prevent, service or control RMSF. References
5. Alvarez-Hernández G (2010) Rocky Mountain spotted fever, a forgotten epidemic. Salud Publica Mex 52: 1-3.
1. Demma LJ, Traeger MS, Nicholson WL, Paddock CD, Blau DM, et al. (2005) Rocky Mountain spotted fever from an unexpected tick vector in Arizona. N Engl J Med 353: 587-94.
2. Buckingham SC (2005) Tick-borne infections in children: epidemiology, clinical manifestations, and optimal management strategies. Paediatr Drugs 7: 163-76.
3. Álvarez-HG, Contreras-Soto JJ (2013) Rocky Mountain spotted fever fatality in children from a public pediatric hospital in Sonora, Mexico, 2004-2012. Salud Publica Mex 55: 151-2
8. Helmick CG, Bernard KW, D’Angelo LJ (1984) Rocky Mountain spotted fever: clinical, laboratory, and epidemiological features of 262 cases. J Infect Dis 150: 480-8.
4. Openshaw JJ, Swerdlow DL, Krebs JW, Holman RC, Mandel E, et al. (2010) Rocky mountain spotted fever in the United States, 2000-2007: interpreting contemporary increases in incidence. Am J Trop Med Hyg 83: 174-82.
6. Holman RC, McQuiston JH, Haberling DL, Cheek JE (2009) Increasing incidence of Rocky Mountain spotted fever among the American Indian population in the United States. Am J Trop Med Hyg 80: 601-5.
7. Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever, Ehrlichioses, and Anaplasmosis -United States (2006) A Practical Guide for Physicians and Other Health-Care and Public Health Professionals 55: 1-27.
10.Masters EJ, Olson GS, Weiner SJ, Paddock CD (2003) Rocky Mountain spotted fever: a clinician’s dilemma. Arch Intern Med 163: 769-74.
11. Zientek J, Dahlgren FS, McQuiston JH, Regan J (2014) Self-reported treatment practices by healthcare providers could lead to death from Rocky Mountain spotted fever. J Pediatr 164: 416-8.
12. Suárez R, Beltrán EM, Sánchez T (2006) The sense of risk from medical anthropology: consonance and dissonance with two public health communicable diseases. Antípoda Rev Antropol Arqueol 3: 123-54.
9. Dantas-Torres F (2007) Rocky Mountain spotted fever. Lancet Infect Dis 7: 724-32.
13. Demma LJ, Holman RC, Mikosz CA, Curns AT, Swerdlow DL, et al. (2006) Rocky mountain spotted fever hospitalizations among American Indians. Am J Trop Med Hyg 75: 537-41. Acknowledgement
We’d like to thank the Leaders across Borders program for the opportunity to share this case study with their 2013 student cohort as part of their bi-national leadership training. The Leaders across Borders program is funded by the US Mexico Border Health Commission.Borders program is funded by the US Mexico Border Health Commission.
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Journal of Case Reports and Studies
15. Stafford III KC (2007) Tick management handbook. The Connecticut Agricultural Experimental Station.
16. Parola P, Socolovschi C, Jeanjean L, Bitam I, Fournier PE, et al. (2008) Warmer weather linked to tick attack and emergence of severe rickettsioses. PLoS Negl Trop Dis 2: e338.
17. Álvarez-Hernández G, Aranda-Gallegos P, Candia-Plata MC, Bolado-Martínez E, López-Soto LF, et al. (2013) Tuberculosis in agricultural migrants indigeneous agricultural workers in Sonora. Rev Región Soc 58: 5-28.
14. Paddock CD, Brenner O, Vaid C, Boyd DB, Berg JM, et al. (2002) Short report: concurrent Rocky Mountain spotted fever in a dog and its owner. Am J Trop Med Hyg 66: 197-9.
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Volume 1 | Issue 6