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Rock Health Demo Day
9/24/13
ThriveOn – Mental Health on demand
Alejandro Foung, Nick Letourneau (Trulia)
Changing the way people think of and access mental health
80M adults diagnosed, 1/10 seek help
Conducted interviews (pts, professionals) and 3 issues: stigma, access, and cost
Happy body + happy mind = my health
On demand clinically validated mental health programs
Assessment – answer questions and develop a custom program
Algorithm pairs programs to individual needs
Mobile access and a remote coach
First market is universities for body image issues (90% of female college students unhappy with bodies)
25% of freshmen have an eating disorder by the end of their freshman year
2 years of study at Stanford and WashU in 3,000 students  50% reduction in eating disorders
5x more use, 1/5
th
of therapist time, 1/10
th
of cost
$2M grant to use across the country for HBI (healthy body image)
$1B university market: will cover 45 universities this fall
Next markets are stress mgmt, anxiety disorders, depression, and disordered sleep
$400k raised
CancerIQ
Feyi Olopade (Wharton), Haibo Lu (data scientist for Chinese men’s basketball team)
Big data in oncology
Trying to bridge the gap between the Top 10 cancer care centers and the other 90% (where survival rates are 70%)
Academic medical centers see a lot of patients and process a lot of data
Community oncologists have more difficulty identifying patterns
Search your own institution for a similar patient profile
Secure data sharing platform for second opinions; enriched by thousands of patients
Monitor and track patients over time; see statistics on recurrence
“Where you live will no longer determine how long you live”
Retain 20% of pts that are lost to academic medical centers = $750k annual gain
Providers required to understand genetic risks at an annual cost of $250k
$1M in value created for clinics x 7k clinics = $7B opportunity
7 yrs of R&D, 7M public records, 70k patients of testing at UChicago
Partners include: NCI, CtyofHope, UChicago, Cleveland Clinic, Fox Chase, Memorial Sloan-Kettering, and Dana-
Farber
4 paid pilots secured and 4 more on the wait list
$2.5M of grant funding to date
Spire
Team: Jonathan Palley, Neema Morajevi
#1 on Angellist last week
16% of day moving (walking, exercising) = average American
84% of day NOT moving
100% of day breathing
Started by head of calming technology lab at Stanford
Today: spirometry, but tomorrow: movement and respiration tracker worn on waistband or bra strap
Pre-production occurring in China
Study: LinkedIn employees who wore Spire  75% improved productivity, 2/3 were more focused
Milestones: pilots with prototypes (major employers, occurring now); crowdfunding; large-scale production (next year)
Augmedix
Co-Founders: Ian Shakhil, Pelu Tran
20 employees, 4 pilot sights, venture backed
Started by scoping out every healthcare use case
Focus: a quarter of a MDs day is spent on their EMR system
Re-humanize the doctor-patient interaction and bring about efficiency gains
Documentation/communication burden is sky high
Points of view video
99% patient acceptance at 3 pilot sights
Patient education component: explain to pt why doctor is using and how the video is being used
Smart Patients: Social and Science
Ronnie Zieger (chief health strategist at Google)
Patients learn from each other: “What have you experienced? Where are you getting 2
nd
opinions?” etc
Search engine to find clinical trials… Yelp for clinical trials (active discussion of what trials are attractive)
Analysis of patient conversations; insertion of structured questions to get feedback for partners (ie: clinical study
design, attractiveness of various study components)
Market research + clinical trial search + patient engagement
Raising a seed round
Anapsis
Co-Founders: Rustam Lalkaka (Microsoft) and Tyler Jorgenson (ZS, Capital One)
Platform for data science algorithms
Enterprise sharing? Email is not good.
Publish an algorithm and share with the people who need it
Execution on the web: supply data sets and set parameters and get the results in the browser
Security, audit, and compliance
Business users get the answers they need
anapsis.com
CRIXlabs
CTO: Shalini Ananda
Better targeting of cancer drugs by simulation with NuSilico system
10 yrs of research went into the product
Have looked at 75% of nanotherapies that exist today; high level of correlation between NuSilico predictions and lab
results
39 months of experiment time at the bench can be simulated by computers in 1 month
Tool runs in the cloud; easy for pharma to access
CRIXlabs.com
Lift Labs
CEO: Anupam Pathak
Actively stabilize tremors in Parkinson’s patients
10% of people 60+ end up with essential tremor
50% of time, the Rxs fail
As a last resort, pts turn to neurostim surgery
LiftWare uses active cancellation
Used in high end SLR cameras to cancel motion
Multiple attachments coming soon (fork, knife, etc… starting with spoon)
Clinical trials at UMich  avg 70% tremor cancellation
Product launched with the help of IETF (Intl Essential Tremor Foundation) and sold 200 in first week
Collecting donations
Sensentia
Co-Founders: Jan Jungclaus, Ronen Amit
Automate previously manual tasks
Benefits eligibility inquiries, claims processing, real-time adjudication
Move from phone to web and mobile based (10x increase in speed with 97% accuracy)
Ran real call center questions at an accuracy rate higher than an agent can provide
$3-5B provider costs, $25B member costs
Business model is a 2:1 ROI
Technology is based on breakthroughs in computational comprehension
Understands logic and structure
Scales to 200 policies or more
First customer is a top 5 health insurer
Moving to first field implementation
Amplify Health
CEO: Eric Page, Kathy Sidenblad, Arjun Rao
Amplify the strength of PCPs and reassert role as principal navigator in patient’s health journey
PCPs generate less than 5% of the healthcare pie but influence almost all of it
Contract directly with self-insured employers ($25B market)
Example: Redirect Health (provider) – Arrowhead (employer) at $850/patient
Mandate: Lower costs, improve outcomes
Give feedback to re-direct based on claims data
Surface deviations and allow the provider to catch instances of
Early results: 30% hospital spend down
Have two largest PCP orgs in country
John Lincoln = first customer

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Rock Health Demo Day Notes

  • 1. Rock Health Demo Day 9/24/13 ThriveOn – Mental Health on demand Alejandro Foung, Nick Letourneau (Trulia) Changing the way people think of and access mental health 80M adults diagnosed, 1/10 seek help Conducted interviews (pts, professionals) and 3 issues: stigma, access, and cost Happy body + happy mind = my health On demand clinically validated mental health programs Assessment – answer questions and develop a custom program Algorithm pairs programs to individual needs Mobile access and a remote coach First market is universities for body image issues (90% of female college students unhappy with bodies) 25% of freshmen have an eating disorder by the end of their freshman year 2 years of study at Stanford and WashU in 3,000 students  50% reduction in eating disorders 5x more use, 1/5 th of therapist time, 1/10 th of cost $2M grant to use across the country for HBI (healthy body image) $1B university market: will cover 45 universities this fall Next markets are stress mgmt, anxiety disorders, depression, and disordered sleep $400k raised CancerIQ Feyi Olopade (Wharton), Haibo Lu (data scientist for Chinese men’s basketball team) Big data in oncology Trying to bridge the gap between the Top 10 cancer care centers and the other 90% (where survival rates are 70%) Academic medical centers see a lot of patients and process a lot of data Community oncologists have more difficulty identifying patterns Search your own institution for a similar patient profile Secure data sharing platform for second opinions; enriched by thousands of patients Monitor and track patients over time; see statistics on recurrence “Where you live will no longer determine how long you live” Retain 20% of pts that are lost to academic medical centers = $750k annual gain Providers required to understand genetic risks at an annual cost of $250k $1M in value created for clinics x 7k clinics = $7B opportunity 7 yrs of R&D, 7M public records, 70k patients of testing at UChicago Partners include: NCI, CtyofHope, UChicago, Cleveland Clinic, Fox Chase, Memorial Sloan-Kettering, and Dana- Farber 4 paid pilots secured and 4 more on the wait list $2.5M of grant funding to date Spire Team: Jonathan Palley, Neema Morajevi #1 on Angellist last week 16% of day moving (walking, exercising) = average American 84% of day NOT moving 100% of day breathing Started by head of calming technology lab at Stanford Today: spirometry, but tomorrow: movement and respiration tracker worn on waistband or bra strap Pre-production occurring in China Study: LinkedIn employees who wore Spire  75% improved productivity, 2/3 were more focused Milestones: pilots with prototypes (major employers, occurring now); crowdfunding; large-scale production (next year)
  • 2. Augmedix Co-Founders: Ian Shakhil, Pelu Tran 20 employees, 4 pilot sights, venture backed Started by scoping out every healthcare use case Focus: a quarter of a MDs day is spent on their EMR system Re-humanize the doctor-patient interaction and bring about efficiency gains Documentation/communication burden is sky high Points of view video 99% patient acceptance at 3 pilot sights Patient education component: explain to pt why doctor is using and how the video is being used Smart Patients: Social and Science Ronnie Zieger (chief health strategist at Google) Patients learn from each other: “What have you experienced? Where are you getting 2 nd opinions?” etc Search engine to find clinical trials… Yelp for clinical trials (active discussion of what trials are attractive) Analysis of patient conversations; insertion of structured questions to get feedback for partners (ie: clinical study design, attractiveness of various study components) Market research + clinical trial search + patient engagement Raising a seed round Anapsis Co-Founders: Rustam Lalkaka (Microsoft) and Tyler Jorgenson (ZS, Capital One) Platform for data science algorithms Enterprise sharing? Email is not good. Publish an algorithm and share with the people who need it Execution on the web: supply data sets and set parameters and get the results in the browser Security, audit, and compliance Business users get the answers they need anapsis.com CRIXlabs CTO: Shalini Ananda Better targeting of cancer drugs by simulation with NuSilico system 10 yrs of research went into the product Have looked at 75% of nanotherapies that exist today; high level of correlation between NuSilico predictions and lab results 39 months of experiment time at the bench can be simulated by computers in 1 month Tool runs in the cloud; easy for pharma to access CRIXlabs.com Lift Labs CEO: Anupam Pathak Actively stabilize tremors in Parkinson’s patients 10% of people 60+ end up with essential tremor 50% of time, the Rxs fail As a last resort, pts turn to neurostim surgery LiftWare uses active cancellation Used in high end SLR cameras to cancel motion Multiple attachments coming soon (fork, knife, etc… starting with spoon) Clinical trials at UMich  avg 70% tremor cancellation Product launched with the help of IETF (Intl Essential Tremor Foundation) and sold 200 in first week Collecting donations
  • 3. Sensentia Co-Founders: Jan Jungclaus, Ronen Amit Automate previously manual tasks Benefits eligibility inquiries, claims processing, real-time adjudication Move from phone to web and mobile based (10x increase in speed with 97% accuracy) Ran real call center questions at an accuracy rate higher than an agent can provide $3-5B provider costs, $25B member costs Business model is a 2:1 ROI Technology is based on breakthroughs in computational comprehension Understands logic and structure Scales to 200 policies or more First customer is a top 5 health insurer Moving to first field implementation Amplify Health CEO: Eric Page, Kathy Sidenblad, Arjun Rao Amplify the strength of PCPs and reassert role as principal navigator in patient’s health journey PCPs generate less than 5% of the healthcare pie but influence almost all of it Contract directly with self-insured employers ($25B market) Example: Redirect Health (provider) – Arrowhead (employer) at $850/patient Mandate: Lower costs, improve outcomes Give feedback to re-direct based on claims data Surface deviations and allow the provider to catch instances of Early results: 30% hospital spend down Have two largest PCP orgs in country John Lincoln = first customer