Coronaviruses are a group of viruses that cause respiratory illness in humans and other animals. COVID-19 is an infectious disease caused by the SARS-CoV-2 coronavirus. Common symptoms include fever, cough, and shortness of breath. While most cases result in mild symptoms, some can lead to pneumonia or multiple organ failure. The virus spreads primarily through respiratory droplets when people are in close contact. There is no vaccine yet, so prevention focuses on hand washing, social distancing, and isolation for those who may be infected. Identification of new coronaviruses can be done using cDNA-AFLP, which allows expression analysis without prior genome sequence knowledge.