Learning Objectives are:
1. To understand Resins, their formation in plants and chemistry.
2. To know various types and combinations of resins.
3. To learn and comprehend the pharmacognostic features of various plant containing resins.
4. To have knowledge of various official preparations of resin drugs.
Resin and his combination
1)CONTENT
2)DEFINITION
3)METHOD OF EXTRACTION
4)PROPERTIES
5)CLASSIFICATION
6)COMBINATION OF RESIN
Definition-Resin is a solid or highly viscous organic substance exuded by various trees or can be produced synthetically.
Synonym – Rosin
Resins are secondary metabolites produced by higher plants and are nothing but oxidative products of terpenes
Method of Extraction-Extraction by using a solvent
Extraction by Distillation
Extraction by Making an incision
Extraction by Heating the plant part Containing resin
Extraction of resin From Encrustation
Properties-Physically:– Resins are usually hard, transparent, or translucent. When heated, they soften and finally melt.
Chemically:- They are complex mixtures of resin acids, resin alcohols, resin phenols(resinotannols).
Solubility:- Insoluble in water &petroleum spirit.Soluble in alcohol, chloroform & ether
Classification-Based on the occurrence, it is classified into five types-
Oleo resin
Gum resin
Oleo-Gum resin
Glycerin
Balsam
Based on Chemical Constituent, It is classified as
Resin acid/Resinolic Acid
Resin Alcohol/Resin Ester
Resines/Inert Resin
Combination of resin-BENZOIN
GUGGUL
GINGER
ASAFOETIDA
MYRRH
COLOPHONY
Resin and his combination
1)CONTENT
2)DEFINITION
3)METHOD OF EXTRACTION
4)PROPERTIES
5)CLASSIFICATION
6)COMBINATION OF RESIN
Definition-Resin is a solid or highly viscous organic substance exuded by various trees or can be produced synthetically.
Synonym – Rosin
Resins are secondary metabolites produced by higher plants and are nothing but oxidative products of terpenes
Method of Extraction-Extraction by using a solvent
Extraction by Distillation
Extraction by Making an incision
Extraction by Heating the plant part Containing resin
Extraction of resin From Encrustation
Properties-Physically:– Resins are usually hard, transparent, or translucent. When heated, they soften and finally melt.
Chemically:- They are complex mixtures of resin acids, resin alcohols, resin phenols(resinotannols).
Solubility:- Insoluble in water &petroleum spirit.Soluble in alcohol, chloroform & ether
Classification-Based on the occurrence, it is classified into five types-
Oleo resin
Gum resin
Oleo-Gum resin
Glycerin
Balsam
Based on Chemical Constituent, It is classified as
Resin acid/Resinolic Acid
Resin Alcohol/Resin Ester
Resines/Inert Resin
Combination of resin-BENZOIN
GUGGUL
GINGER
ASAFOETIDA
MYRRH
COLOPHONY
Resins are secondary metabolite obtained from nature having so many pharmacological and therapeutic uses and this chapter is included in Phytochemistry and Pharmacognosy subject syllabus of 5th semester B.Pharm course.
It includes Definition,Properties,Classification.Individual drugs including Asafoetida,Guggul,.Myrrh,Colophony,Benzoin etc.
Resins are amorphous products of complex chemical nature. They are transparent or translucent solids, semi-solids or liquid substances containing large number of carbon atoms. They are hard, electrically non-conductive and combustible masses. They are usually formed in schizogenous or schizolysigenous cavities or ducts as end products of metabolism.
Most of the resins are heavier than water. They are insoluble in water, but soluble in alcohol, volatile oils, fixed oils, chloral hydrate and non-polar organic solvents like benzene and ether.
Definition
noun, plural: volatile oils
A substance of oily consistency and feel especially one that is derived from a plant tissue (in contrast to fatty oil that does not evaporate when exposed to air and saponifies)
Supplement
Volatile oils are oils that are characterized by their volatility and failure to saponify. They evaporate when they are exposed to the air and thus are capable of distillation. They are derived from plant tissues. Thus, they may be produced naturally by extraction, particularly by distillation, often by using steam. They may also be made synthetically.
As medicines, volatile oils are used as stimulants, stomach aches, correctives, and carminatives. Other use of volatile oil is for purposes of flavoring (e.g., peppermint oil). But the most common use of volatile oil is for the production of perfumes, cosmetics, soaps, and the like.
Volatile oil is sometimes called an essential oil. An essential oil is known for being a concentrated hydrophobic liquid with plant-derived, volatile aroma compounds. It is referred to as essential since it contains what seems to be the essence of the plant’s fragrance.
Resins are secondary metabolite obtained from nature having so many pharmacological and therapeutic uses and this chapter is included in Phytochemistry and Pharmacognosy subject syllabus of 5th semester B.Pharm course.
It includes Definition,Properties,Classification.Individual drugs including Asafoetida,Guggul,.Myrrh,Colophony,Benzoin etc.
Resins are amorphous products of complex chemical nature. They are transparent or translucent solids, semi-solids or liquid substances containing large number of carbon atoms. They are hard, electrically non-conductive and combustible masses. They are usually formed in schizogenous or schizolysigenous cavities or ducts as end products of metabolism.
Most of the resins are heavier than water. They are insoluble in water, but soluble in alcohol, volatile oils, fixed oils, chloral hydrate and non-polar organic solvents like benzene and ether.
Definition
noun, plural: volatile oils
A substance of oily consistency and feel especially one that is derived from a plant tissue (in contrast to fatty oil that does not evaporate when exposed to air and saponifies)
Supplement
Volatile oils are oils that are characterized by their volatility and failure to saponify. They evaporate when they are exposed to the air and thus are capable of distillation. They are derived from plant tissues. Thus, they may be produced naturally by extraction, particularly by distillation, often by using steam. They may also be made synthetically.
As medicines, volatile oils are used as stimulants, stomach aches, correctives, and carminatives. Other use of volatile oil is for purposes of flavoring (e.g., peppermint oil). But the most common use of volatile oil is for the production of perfumes, cosmetics, soaps, and the like.
Volatile oil is sometimes called an essential oil. An essential oil is known for being a concentrated hydrophobic liquid with plant-derived, volatile aroma compounds. It is referred to as essential since it contains what seems to be the essence of the plant’s fragrance.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. Learning Objectives
Learning Objectives are
1. to understand Resins, their formation in plants
and chemistry.
2. To know various types and combinations of
resins.
3. To learn and comprehend the pharmacognostic
features of various plant containing resins.
4. To have knowledge of various official
preparations of resin drugs.
8. Hard , transparent, and brittle.
1
Usually amorphous in nature.
2
Upon, heating resin gets softened and finally
melt.
3
Insoluble in water but solublen organic
solvents like alcohol, ether and chloroform.
4
5
In the presence of fir or oxygen, they burn
with smoke due to large number of carbon.
10. Resin:
chemistry
Also called resinolic acids,
Are of high molecular weight
and very complex.
They may occur free, or in some
resins, e.g. 90 per cent or more of
colophony consists of the resin
acid; abietic acid.
Examples of resin acid:-
1. abietic acid
2. Commiphorie acid
1.Resin
acid:
11. Resin:
chemistry
Complex alcohols of higher
molecular weight.
Occur either in Free State or
as esters with aromatic acid
e.g. cinnamic acid and
benzoic acid.
Ferulic acid in asafoetida
2.Resin
alcohols:
12. They are tannins in nature and give blue color
with FeCl3.
Named after their source:
1.Toluresinotannols obtained from tolubalsam,
2.Sumaresinotannol from Sumatra
Resin alcohols:
classification
They are colourless and give negative reaction
with ferric salt
E.g. benzoresinol form styrex benzoin.
2.Resinols
1.Resinotannols
13. Resin:
chemistry
They are oxygenated compounds
and do not form salt or esters and
insoluble in alkali.
They are resistant to different climate
conditions and heat, moisture and
chemical reagents that is why they are
used in manufacturing varnishes
They are named from their source
e.g. dracoresene: from daemonorops
Draco, Sandaracorese from sandarac
3.Resenes:
Resin Composition cont...
20. How oleoresin is obtained?
Portion of the
solvent extract
is drawn off
when it contains
10% of the solid
material.
It is then
extracted
using
alcohol/aceton
e as a solvent.
Dried ginger
is gruond
to a coarse
powder.
Step 1 Step 2 Step 3
Solvent is
evaporated to
obtain a
massy,
resinous
material.
Step 2
22. Ginger-uses cont.
Anti-emetic
Diarrhoea
As fragrant compound in cosmetic
products including soaps, detergents,
creams, lotions and perfumes.
used in preparation of soft drinks,
e.g:Ginger ale:sugar, ginger extract and
carbonated water
23. Tinctura
Zingiberis (U. S.
P.)—Tincture of
Ginger
Oleoresin of
Ginger-U.S.P
Preparation: Powdered
ginger macerated and
percolated with alcohol.
Uses: Carminative,
stimulant, preparation of
ginger syrup
Dose: 10 to 60 drops in a
sweetend drink
Preparation: Ginger
powder extraction with
ether/alcohol.
Uses: same as ginger.
Dose: 1 minim well
diluted
24.
25. Botanical Origin: Capsicum annum
Capsicum frutesens
Family: Solanaceae
Parts used: Dried Ripen fruit
Descripttion:
•Colour- orange, red
•Odour- aromatic
•Taste –pungent,
irritating
26. Capsaicin: a pungent principal which is
presnt in higher amount in dissepiments.
It also contains:
volatile oil,
fixed oil,
carateniods,
ascorbic acid.
27. The solvent is
then evaporated,
and the
remaining wax
like resin is the
oleoresin-
capsicum
This powder
undergoes
extraction in an
organic solvent
such as ethanol.
Capsicum is
finely ground.
Step 1 Step 2 Step 3
29. Fluid Extract of
Capsicum U.S.P
Preparation: Powdered
capsicum is macerated and
percolated with alcohol and
diluted.
Uses: All uses of capsicum.
Dose: ½ to 2 minims
Official Preparation:
30.
31. Botanical origin: Ferula foetida
Ferula asafoetida
Family: Apiaceae
Parts used: Oleogum resin from rhizome n
roots
Plant description:
Herbaceous perennia
Odour-Pungent when ra
Colour- fresh resin is white,
turns amber when dries.
Asafoetida
32. Constituents:
Contain volatile oil, gums and resins.
The principle constituents of
volatile oil is isobutyl propyl
disulphide.
The principle constituents of resins
are asaresinol, asaresene, ferulic
acid, and isoferrulic acid.
34. Step 1
Step 2
Step 3
Step 4
•. When the leaves begin to decay, the root-
leaves and stem are twisted off close to the
root.soil is removed.
• The gum-resin is obtained by incisions into the upper
part of the root, or by slicing it successively in small
pieces
• A milky juice of a fetid, alliaceous odor gradually
exudes.
• When this exudation hradens, it is scraped off, and
another thin slice removed as before, from which
juice again flows,
• process is repeated until no more juice can be
obtained
How oleoresin is obtained??
Step 5
• . The concrete juice from several plants are the
put together, further hardened and carried aw
37. Pills of
Asafoetida
U.S.P
EMULSION OF
ASAFETIDA
U.S.P
Preparation: Asafoetida
and powdered hard soap
distilled with water.
Uses: Flatulent
indigestion.
Dose: 1 to 2 pills
Preparation: Asafoetida
tears distilled with water
Uses: This is best
preparation of asafoetida,
used as enema.
Dose: ½ to 1 fluid ounce
Official preparations of Asafoetida:
38. L O G O
1. Trease and Evans’ Pharmacognosy, William C.
Evans, George E. Trease, Daphne Evans, 16th ed.,
Illustrated Elsevier Health Sciences Division
Publisher (2009).
2. Tyler V.E., Brady E.R. and Robbers J.E.
Pharmacognosy, 9th ed., Lea & Febiger,
Philadelphia
3. Biologically Active Natural Products:
Pharmaceuticals, Horace G. Cutler, Eds., Illustrated
Edition, CRC Press Publisher, New York (2000).