This document discusses periodontal regeneration techniques. It defines regeneration as the renewal of tissues through growth and differentiation of new cells. Repair restores continuity but does not result in new attachment. New attachment embeds new periodontal ligament fibers into cementum. Autografts use bone from the patient while allografts use bone from others. Various graft materials, membranes, and biological modifiers are discussed that can enhance periodontal regeneration results. Maintaining good oral hygiene is important for sustaining positive outcomes.
The periodontal dressing is a physical barrier that is placed in the surgical site to protect the healing tissues from the forces produced during mastication, for comfort and close adaptation.
Gingivectomy and gingivoplasty are the periodontal surgical procedures. It was first introduced by Pierre fauchard. It is used in pocket elimination by gingival resection whereas gingivoplasty refers to recontouring of gingiva in the absence of pockets.
The periodontal dressing is a physical barrier that is placed in the surgical site to protect the healing tissues from the forces produced during mastication, for comfort and close adaptation.
Gingivectomy and gingivoplasty are the periodontal surgical procedures. It was first introduced by Pierre fauchard. It is used in pocket elimination by gingival resection whereas gingivoplasty refers to recontouring of gingiva in the absence of pockets.
Biologic width - Importance in Periodontal and Restorative DentistryDr.Shraddha Kode
Biologic width plays a vital role for preservation of the periodontal health. This concept involves the dimensions of the epithelial and connective tissue attachment between the base of the sulcus and the alveolar crest which if involved can lead to gingival inflammation and gingival recession.
The future of dentistry and periodontics lies in regeneration. The goals of periodontal therapy lies in not only the arrest of periodontal disease progression but also regeneration of the lost periodontal structures. This presentation provides a review of the current understanding of the regeneration of the periodontium and the procedures involved to restore the periodontal tissues around the teeth.
Periodontitis is a complex infection initiated by bacteria –tissue destruction.
Host: the organism from which a parasite obtains its nourishment/ an individual who receives a graft
Modulation: the alteration of function or status of something in response to a stimulus or an altered physical or chemical environment
This presentation describes the gingival recession, its classifications and theories of pathogenesis and different etiological factors in its progression.
INTRODUCTION
DEFINITION
TYPES OF TRAUMA FROM OCCLUSION
GLICKMAN CONCEPT
WAERHAUG CONCEPT
STAGES OF TISSUE RESPONSE TO INJURY
CLINICAL AND RADIOGRAPHIC FEATURES OF TFO
CLINICAL DIAGNOSIS OF TFO
TFO AND IMPLANTS
TREATMENT OF TFO
CONCLUSION
REFRENCES
Biologic width - Importance in Periodontal and Restorative DentistryDr.Shraddha Kode
Biologic width plays a vital role for preservation of the periodontal health. This concept involves the dimensions of the epithelial and connective tissue attachment between the base of the sulcus and the alveolar crest which if involved can lead to gingival inflammation and gingival recession.
The future of dentistry and periodontics lies in regeneration. The goals of periodontal therapy lies in not only the arrest of periodontal disease progression but also regeneration of the lost periodontal structures. This presentation provides a review of the current understanding of the regeneration of the periodontium and the procedures involved to restore the periodontal tissues around the teeth.
Periodontitis is a complex infection initiated by bacteria –tissue destruction.
Host: the organism from which a parasite obtains its nourishment/ an individual who receives a graft
Modulation: the alteration of function or status of something in response to a stimulus or an altered physical or chemical environment
This presentation describes the gingival recession, its classifications and theories of pathogenesis and different etiological factors in its progression.
INTRODUCTION
DEFINITION
TYPES OF TRAUMA FROM OCCLUSION
GLICKMAN CONCEPT
WAERHAUG CONCEPT
STAGES OF TISSUE RESPONSE TO INJURY
CLINICAL AND RADIOGRAPHIC FEATURES OF TFO
CLINICAL DIAGNOSIS OF TFO
TFO AND IMPLANTS
TREATMENT OF TFO
CONCLUSION
REFRENCES
The future of dentistry and periodontics lies in regeneration. The goals of periodontal therapy lies in not only the arrest of periodontal disease progression but also regeneration of the lost periodontal structures. This presentation provides a review of the current understanding of the regeneration of the periodontium and the procedures involved to restore the periodontal tissues around the teeth.
Reconstructive periodontal therapy
Some of the slides may appear Blank/White/Black, those are the Videos that I added in the presentation.
Kindly Ignore those slides.
This presentation reviews common functional and esthetic problems associated with extraction of teeth and current methods and surgical techniques to minimize loss of bone and soft tissue
Bioactive materials are revolutionizing oral health care and the quest for newer materials is never ending especially in the field of dental science. Research on biomaterials intensely involves interdisciplinary contributions from several major areas and requires extensive knowledge of medical science, materials science, biochemistry, biomedical engineering and clinical science. They are broadly used in the field of conservative dentistry and periodontics for regeneration, repair and reconstruction by acting directly on the vital tissue inducing its healing and repair through induction of various growth factors and different cells. This article reviews on the properties and clinical application of newer bioactive materials in endodontics, with a primary focus on the biocompatibility and tissue response to these materials.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
2. What is Regeneration
Regeneration is the natural renewal of a
structure, produced by growth and
differentiation of new cells and
intercellular substances to form new
tissues or parts
3. Repair:
It restores the continuity of the diseased
marginal gingival and re-establishes a
normal gingival sulcus.
This process heals by scar arrest bone
destruction but doesn’t result in gain of
gingival attachment or bone height.
4. New Attachment
It is the embedding of new periodontal
ligament fibres into new cementum and
attachment of gingival epithelium to a
tooth surface previously denuded by
disease.
11. 1. Nontoxic
2. Nonantigenic
3. Resistant to infection
4. Predictability
5. Clinical feasibility
6. Easy adaptability
7. Readily and sufficiently available
8. Minimal operative and postoperative hazards
9. Adequate bone fill and promotion of new
attachment in- cluding cementogenesis
10. Cost effective and acceptable to the patient
14. Sources of bone include
Bone from healing extraction wounds
Bone from edentulous ridges
Bone trephined from within the jaw without
damaging the roots
Bone re- moved from tuberosity or
the ramus
Bone removed during osteoplasty and
ostectomy
15. Osseous Coagulum
• It is a mixture of bone dust and blood.
• The technique uses small particles ground from
cortical bone.
16. Bone Blend
• To overcome these problems, the "bone blend
technique" has been proposed.
• The bone blend technique uses an autoclaved
plastic capsule and pestle.
• Bone is removed from a predetermined site,
triturated in the capsule to a workable, plastic-
like mass and packed into bony defects
17.
18. Bone Swaging
The bone swaging technique requires an
edentulous area adjacent to the defect, from
which the bone is pushed into contact with the
root surface without fracturing the bone at its
base
19. • The use of fresh or preserved iliac cancellous marrow,
bone has been extensively investigated
• Because of numerous problems associated with its use,
the technique is no longer in use.
• Some of the problems were:
Postoperative infection
Bone exfoliation
Sequestration
Varying rates of healing
Root resorption
Rapid recurrence of the defect
Bone from extraoral site
20.
21.
22. Freeze-Dried Bone Allograft
• It is considered an osteoconductive material.
• FDBA being slow resorbing is often used in
guided bone regeneration.
23. Demineralized Freeze-Dried Bone
Allograft
• It is considered an osteoinductive
graft.
• DFDBA has a higher osteogenic
potential
• Demineralization in cold, diluted
hydrochloric acid exposes the
components of bone matrix, which
are closely associated with collagen
fibrils and have been termed bone
morphogenetic proteins (BMPs)
24.
25. • Calf bone (Boplant), treated by detergent
extraction, sterilized and freeze dried, has been
used for the treatment of osseous defects.
• Kiel bone and anorganic bone derived from ox
were used previously which were discarded.
26. Bio-Oss
• Currently, an anorganic, bovine-derived bone
marketed under the brand name Bio-Oss
(Osteohealth) has been successfully used both
for periodontal defects and in implant surgery.
• It is an osteoconductive,
porous bone mineral matrix
from bovine cancellous or
cortical bone.
27.
28.
29. It includes
Plaster of Paris
Ceramics
Polymers
Bioactive glasses
Coral-derived materials
30. Calcium Phosphate Biomaterials
These materials are osteoconductive and, therefore, act as a
scaffold for blood clots to be retained to allow bone formation.
Two types of calcium phosphate ceramics have been used:
Hydroxyapatite –
o calcium-to-phosphate ratio of 1.67
o Non bioresobable
Tricalcium phosphate-
o calcium-to-phosphate ratio of 1.5
o partially bioresorbable
31. Bioactive Glass
• Bioactive glass consists of sodium and calcium salts,
phosphates, and silicon dioxide
• For its dental applications, it is used in the form of
irregular particles measuring
90-170 µm (PerioGlas, Block Drug, Jersey City, NJ)
300-355 µm (BioGran, Ortho Vita, Malvern, PA)
32. Enamel Matrix Derivative
• EMD has been effective in the treatment of
infrabony defects.
• EMD has been shown to be safe for clinical use.
• It was found that radiographic
bone level was restored,
normal clinical attachment
level (CAL) was gained and
pocket depth was reduced.
35. • GTR is used for the prevention of epithelial
migration along the cementa! wall of the pocket and
maintaining space for clot stabilization.
• GTR consists of placing barriers of different types
(membranes) to cover the bone and periodontal
ligament, thus temporarily separating
them from the gingival epithelium and
connective tissue
• GTR is often performed with some type of
bone graft as a scaffolding agent, so it is a
combined therapy.
38. • The first commercial membrane was produced from expanded
polytetrafluoroethylene (ePTFE)
• This membrane has all the properties necessary for GTR barriers in
that it
Is a cellular barrier
Is biocornpatible
Provides space for the healing tissue
Permits tissue integration
Is clinically manageable.
• After membrane placement, healing is allowed to proceed for 4-6
weeks
• After membrane removal, the area should not be probed for 3 months.
Radiographic evidence of bone fill is usually present after 6 months
and should continue over the course of 1 year.
• In intrabony and fur- cation defects, there are gains in CAL (3-6 mm),
improved bone levels (2.4-4.8 mm), and probing depth reductions (3.5-
6 mm).
• The advent of titanium-reinforced ePTFE allowed for the formation of
larger spaces, thus permitting correction of larger defects.
39.
40. BIODEGRADABLE MEMBRANE
There are basically three types of bioresorbable
membranes:
Polyglycoside synthetic polymers
Collagen
Calcium sulfate
41. Several features make these bioresorbable
membranes easier to manage clinically:
They are more tissue compatible than
nonresorbable membranes
The timing for resorption can be regulated by the
amount of cross-linkage in the synthetic polymer
and collagen membrane or the amount of heat-
processed calcium sulfate chips in calcium sulfate
barrier
A second surgical procedure is not required to
retrieve the nonresorbable membrane.
42.
43.
44. • The role of laser in periodontal therapy has
gained popularity
• the use of neodymium-yttrium- aluminum-
gamet (Nd:YAG) to perform surgical LANAP has
been reported for the management of chronic
periodontitis and can potentially result in new
attachment and periodontal regeneration.
47. • Changes in the tooth surface wall of periodontal pockets
interfere with new attachment. Although these obstacles
to new attachment can be eliminated by thorough root
planing, the root surface of the pocket can be treated to
improve its chances of accepting the new attachment of
gingival tissues.
• Several substances have been proposed for this
purpose including
Citric acid
Fibronectin
Tetracycline.
50. • The natural healing process usually results in tissue
scarring or repair.
• Using tissue engineering, the wound healing process is
manipulated so that tissue regeneration occurs.
• It consists of three key elements:
51. • Tissue engineering principles include the use of
bone allografts and autologous platelet-rich
plasma (PRP).
• Tissue engineering is now clinically applicable
with two commercially available tissue-
engineering systems for periodontal
regeneration which involve the use of EMD and
platelet derived growth factor BB (PDGF-BB)
with beta tricalcium phosphate (TCP).
53. • Platelet-derived growth factor (PDGF) is one of the
earliest growth factors studied for its effect on
wound healing because it is a potent mitogenic and
chemotactic factor for mesenchymal cells in cell
culture
• Histological evidence of periodontal regeneration
was present with excellent furcation fill.
• Recently a biomaterial consisting of 0.3mg/ml of
rhP- DGF + TCP (GEM21S, Osteohealth, Shirley,
NY) was found to significantly improve attachment
level gain, bone level, and bone volume compared to
TCP alone.
54. CONCLUSION
• Periodontal regeneration continues to be one of the
primary therapeutic approaches toward the management
of periodontal defects.
• Although evidence suggests that present regenerative
techniques can lead to periodontal regeneration, the use
of GTR, and biological modifiers can enhance these
results.
• The maintenance of positive results is highly dependent
on patients oral hygiene habits and compliance with
periodontal maintenance.