Problem-based curricula provide a learning environment where competence is fostered through encouraging inquisitive learning rather than direct teaching of knowledge. Small group discussions, contextual learning integrating knowledge, and emphasizing patient problems have cognitive effects on students, including increased retention, better integration of concepts, development of self-directed learning skills, and increased interest in the subject. Several studies provide evidence for these effects. The document discusses using problem-centered approaches to help students develop conceptual understanding and skills for solving complex problems, as they will need to do in their careers.