Prevalence of Hepatitis B Virus Infection among People Attending a Hepatitis Treatment and Control Centre in Karu, Nigeria

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7th International Scientific Conference on Applied Sciences and Engineering 27-28 February, 2016 Flora Grand Hotel, Dubai

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Abstract of Applied Sciences and Engineering, 2016, Vol.7
DOI: 10.18488/journal.1001/2016.7/1001.7
7th
International Scientific Conference on Applied
Sciences and Engineering
27-28 February, 2016
Flora Grand Hotel, Dubai
Conference Website: www.scihost.org
9
Paper ID: 30/16/ 7
th
ISCASE
Prevalence of Hepatitis B Virus Infection among People
Attending a Hepatitis Treatment and Control Centre in Karu,
Nigeria
Grace Pennap1
--- Danladi HF2
1,2
Microbiology Unit, Nasarawa State University, Keffi, Nasarawa State, Nigeria
Abstract
Hepatitis B virus (HBV) has remained a recurring decimal in vertical transmission,
blood transfusion, liver cirrhosis and hepatocellular carcinoma. This study was
therefore conducted to determine the prevalence of HBV infection in people wishing to
know their serostatus. Six hundred and one people were enrolled for the study. Three
ml of blood was collected from each participant, the serum harvested and tested for
Hepatitis B surface antigen( HBsAg) as the seromarker for HBV infection using a rapid
test kit(ACON USA). Their sociodemographic information was obtained through oral
interview. Of the 601 participants screened, 39.1% were reactive for HBsAg with a sex
stratified prevalence of 32.4% in males and 31.4% in females. With respect to age
those aged 15 years and below had the least infection prevalence(15.4%) while the
highest was among those aged 31 – 35 years(p > 0.05). Other parameters studied as
possible risk factors included marital status, history of HBV vaccination and occupation
(p > 0.05). The present study reported a very high HBV infection prevalence with
obscured risk factors. This is a cause for alarm because of the implication of many
people with the likelihood of transiting to end-stage liver diseases. It is vaccine
preventable so urgent proactive strategies should be put in place for increased vaccine
uptake and prevention and control measures.
Keywords: Hepatitis B Virus, Treatment and Control

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