Thanatology
Types of transplants
Cause, Mechanism of Death
Manner of death
Anoxia
Signs of Death
Immediate Changes (Somatic Death)
Early Changes (Molecular Death)
Algor Mortis ......
Reference
Thanatology
Types of transplants
Cause, Mechanism of Death
Manner of death
Anoxia
Signs of Death
Immediate Changes (Somatic Death)
Early Changes (Molecular Death)
Algor Mortis ......
Reference
the fascial planes of the neck is very important in the spread and containment of infections, as well as being surgical dissection plane during neck surgery.
infections are rare but need to be identified early and treated appropriately to reduce the mortality and morbidity
this is a slightly well illustrated ppt of the previously uploaded one in february 2015
The Larynx: Anatomy, Function, and Disorders
Introduction
The larynx, commonly known as the voice box, is a vital structure in the human body responsible for a multitude of functions, the most prominent of which is voice production. This complex organ plays a crucial role in breathing, swallowing, and protecting the airway. Understanding the anatomy, function, and common disorders of the larynx is essential for grasping its significance in our daily lives. In this comprehensive 2000-word essay, we will explore the larynx in detail, delving into its anatomy, function, the mechanics of voice production, common laryngeal disorders, and their treatment.
I. Anatomy of the Larynx
The larynx is a complex structure located in the neck, connecting the lower part of the pharynx to the trachea. It comprises several cartilages, muscles, ligaments, and other anatomical components that work together to facilitate various functions. To understand the larynx better, it is crucial to break down its anatomy into its constituent parts.
Cartilages
A. Thyroid Cartilage: The thyroid cartilage, often referred to as the Adam's apple, is the most prominent and easily palpable cartilage of the larynx. It is made up of two fused plates and provides structural support to the front of the larynx.
B. Cricoid Cartilage: The cricoid cartilage is a ring-like structure that sits just below the thyroid cartilage. It plays a crucial role in connecting the larynx to the trachea and provides structural support.
C. Epiglottis: The epiglottis is a leaf-shaped cartilage located behind the tongue root. It acts as a lid to cover the entrance of the trachea during swallowing, preventing food and liquids from entering the airway.
D. Arytenoid Cartilages: These paired cartilages are located on top of the cricoid cartilage. They play a pivotal role in controlling vocal cord tension and movement.
E. Corniculate and Cuneiform Cartilages: These smaller cartilages are positioned within the aryepiglottic folds and aid in maintaining the laryngeal structure.
Muscles
A. Intrinsic Laryngeal Muscles: These muscles are responsible for controlling the position and tension of the vocal cords. Key intrinsic muscles include the cricothyroid, thyroarytenoid, lateral cricoarytenoid, posterior cricoarytenoid, and interarytenoid muscles.
B. Extrinsic Laryngeal Muscles: Extrinsic muscles are responsible for moving the larynx as a whole, helping with functions such as swallowing and speech. The sternothyroid, thyrohyoid, and omohyoid muscles are examples of extrinsic laryngeal muscles.
Vocal Cords
The vocal cords, or vocal folds, are a pair of muscular structures located within the larynx. They are composed of layers of mucous membrane, muscle, and connective tissue. The true vocal cords, also known as the vocal ligaments, are the structures primarily responsible for sound production. They are capable of opening and closing rapidly to produce sound when air flows through them.
USMLE MSK L020 Upper 09 Anatomical regions anatomy.pdfAHMED ASHOUR
The upper limb is divided into several anatomical regions, each with distinct structures and functions.
Understanding these anatomical regions is essential for healthcare professionals, anatomists, and individuals studying the upper limb for medical or educational purposes. Each region plays a specific role in the overall function and movement of the upper limb.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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Ppt of anatomy of neck & ML imp
1. Anatomy of Neck & its
Medicolegal importance.
Presenter Dr Gopal G Hargi
PG in FM& T
2. Neck is a very prominent & vital part .Even
trivial injuries can cause death without
showing any signs. There are very vital
structures in a relatively small & unprotected
anatomic region making it very vulnerable to
fatal injuries.
Moreover the Neck is an area which can be
easily grasped and immobilized
5. Lower border of mandible lies b/w C2 & C3.
The front of the lower pharynx & upper
oesophagus lie the larynx & trachea.
On each side of the pharynx is the carotid
sheath,containing the common & internal
carotid arteries & the IJV with the cervical
sympathetic trunk behind it.
The Platysma –a broad flat sheet of muscle
lies superficial to the layers of fascia.
6. Coll’s fascia :The space among the structures of
neck are filled with loose areolar tissue.The
structures of the neck are mostly supplied to move
up & down
.This fascia is a laminar condensation of loose
areolar tissue in neck produced by the movements
of these structures.
These laminar condensations take different names
in different regions & are continuous with each
other or indirectly.
These loose areolar tissue form sheaths which
enclose muscles and their moving structures
7. MODIFICATIONS/
LAMINAE/EXTENSIONS OF DEEP
CERVICAL FASCIA
HAS 7 MODIFICATIONS
1. INVESTING LAYER
2. PRETRACHEAL LAYER
3. PREVERTEBRAL LAYER
4. CAROTID SHEATH
5. BUCCOPHARYNGEAL FASCIA
6. TEMPORAL FASCIA
7. PHARYNGOBASILAR FASCIA
8.
9. INVESTING LAYER
ATTATCHMENTS
ABOVE- EXTERNAL OCCIPITAL PROTUBERANCE,MASTOID PROCESS, EXTERNAL ACOUSTIC
MEATUS, BASE OF THE MANDIBLE
BELOW- SPINE OF SCAPULA, ACROMION PROCESS, CLAVICLE, MANUBRIUM STERNI
FRONT- HYOID BONE & CONTINUOUS WITH THE FASCIA OF THE FASCIA OF THE OPPOSITE
SIDE
BEHIND- 7TH CERVICAL VERTEBRA, LIGAMENTUM NUCHAE
10.
11. CCA ,arises from the left side of AOA.
It lies in the medial part of carotid sheath .
Upper border of C4 the CCA bifurcates.
The carotid pulse can be felt by pressing against
the anterior tubercle of the tranverse process of
C6 vertebra.
ICA ,at its commencment there is a bulge ,
here the arterial wall is thin & contains the
baroreceptors which is supplied by the 9th & 10th
nerves which control the CVS .
carotid body is a small structure behind the
bifurcation of CCA & contains baroreceptors which
maintain oxygen saturation.
12.
13. IJV forms a jugular arch in the suprasternal
space i.e between the sternal & clavicular
head of sternocleadomastoid tendon.
Larynx lies below the hyoid bone in the
midline of the neck at the level of C4-C6
vertebra.
14. The AJV commences beneath the chin & passes
downwards ,side by side beneath the platysma to
the suprasternal region.Here they pierce the deep
fascia & come to lie in the suprasternal space.
Carotid sheath consists of a network of areolar
tissue that surrounds the carotid
arteries(c&i),IJV,Vagus nerve & some deep cervical
lymph nodes.
It is thin where it overlies the IJV ,allowing the
vein to dilate during increased blood flow.
15.
16. The thyroid gland is situated low down at the front
of the neck.The 2 symmetrical lobes are connected
by isthmus which lie in front of 2nd,3rd & 4th
tracheal rings.
Trachea begins at the level of C6 vertebra in
continuity of the larynx,The cervical part lies in
the midline of the neck ,in contact with the front
of the oesophagus.
Oesophagus commences in continuity with the
pharynx at the level of lower border of the cricoid
cartilage(C6).
17.
18. Hyoid bone lies free ,suspended by muscles & so
very mobile .Above its attached to floor of mouth &
tongue,larynx below,behind to epiglottis &
pharynx.It lies at the level of C3 vertebra.
Vertebral artery arises from subclavian artery &
passes up to traverse the foramen of transverse
process of upper 6 cervical vertebras.On emerging
from foramen the artery enters the skull through
foramen magnum
.It pierces the spinal dura mater & archnoid and at
the lower border of pons forms the basillar artery.
19.
20.
21.
22. For judging the severity of the injuries to the neck
its divided into 3 zones.
Zone I
• highest mortality
Zone II
• most frequent site of injury
• lower mortality
Zone III
• neurological
• distal carotids
• pharyngeal injuries
24. (Zone 1)Thoracic inlet (clavicle)to cricoid
cartilage
significant injury in the zone I region may be hidden
from inspection of the chest or the mediastinum.
subclavian vessels
brachiocephalic veins
common carotid artery
jugular vein
aortic arch
Trachea
esophagus
Lung apices
c spine
spinal cord
CN roots
25. Zone 2
Carotid and vertebral
arteries
jugular veins
pharynx
larynx
trachea
esophagus
c spine
spinal cord
Cricoid cartilage to angle of mandible
26. Zone 3
Salivary glands
parotid gland
esophagus
trachea
c spine
Carotid arteries
jugular veins
CN IX - XII
Angle of mandible to base of skull
27. Injury above the level of C4 –rapid death
Due to disruption of CV centre.
Causes- Hyperextension & hyperflexion
Atlanto-occipital injury---fatal: widening of space
with some blood palpated as ‘loosening ‘
Of the junction with widening.Severe form the
articulating condyles of atlas can be seen within
foraen magnum.
C1-C2 injury-- neurogenic shock ,odontoin is #
C2-C3 #( HANGMAN #) rapid
28. Injuries over the region of neck
A) Homicidal:
a)strangulation
i)Ligature ii) Manual
c)bansdola
e)mugging
f)penetrating injuries
a) knife b) gunshot
g)cut throat injuries
h)blunt force impact
i) homicidal ii) accidental
29. Blunt force impact to the side of neck
Shearing
excessive rotation/ hyperextension
◦ distention and stretching
Tearing of Vertebral Artery
The carotids too get dissected ,veins damaged
Blood tracks along upper part of vessel & enters
the cranial cavity producing massive SAH
.
30. Impact Anterior Neck
Impact Anterior Neck
Crush larynx or trachea; cricoid ring
compress esophagus against spinal column
sudden increased intratracheal pressure against
closed glottis (seatbelt), crush bruise (clothesline
tackle)
rapid acceleration/ deceleration results in tracheal
injury
31. B) Suicidal
a)Hanging b)postural asphyxiation
◦ children with neck over object and body weight produces
compression
C)Accidental
i)carotid sleepers ii)bar arm control
a)choking
b)RTA : rapid deceleration hyperflexion,
hyperextension, and rotation vascular structures
are stretched over the cervical spine shearing
forces create intimal tears in the vessel wall
c)toxic gas inhalation
D)Judicial or justified hanging
32. Cause of death in hanging
Asphyxia
Venous congestion
Cerebral oedema
# vertebra
Significant cervical spine and spinal cord damage
can occur in hangings that involve a fall from a
distance greater than the body height.
Cause of death in strangulation
Vagal inhibition
Asphyxia
Cerebral anoxia & Venous congestion
33. Other consequences of Neck Trauma
Subcutaneous emphysema
Tension pneumothorax
Traumatic asphyxia
◦ Penetrating Trauma
Esophagus or Trachea
Vagus nerve disruption
◦ Tachycardia & GI disturbances
Thyroid & Parathyroid glands
◦ High vascular
34. More than 95% of penetrating neck wounds result
from guns and knives, with the remainder resulting
from motor vehicle accidents, household
injuries, industrial accidents, and sporting events
gun shot wound (GSW) sustain greater injury than
those with stab wounds because of a bullet's ability
to penetrate deeper and cause cavitation, thus
damaging structures lying outside the tract of the
missile.
Injury to the blood vessels can also result from
external compression or mural contusion.
Thrombosis is the most common complication of
blood vessel injury, occurring in 25-40% of
patients.
35. Blunt trauma to the neck typically results from
motor vehicle crashes but also occurs with sports-
related injuries (eg, clothesline tackle),
strangulation, blows from the fists or feet, and
excessive manipulation
In motor vehicle crashes, thrusting forward with
the head extended, forcing the anterior neck
against the steering column. Cerebral vessel and
laryngeal injuries secondary to shoulder strap
compression have occurred.
Direct forces can shear the vasculature producing
shearing damage and resultant thrombosis
36. Laryngotracheal Injuries in BNT
Although not prevalent, it is second to only
intracranial injury as the most common cause of
death among patients with head and neck trauma
and is a clinically important injury.
◦
◦ 60% of all external laryngotracheal traumas are due to
blunt neck trauma.
The final common pathway of laryngotracheal
injury is compressive force on the larynx leads to
injury. This is modified by the degree of laryngeal
calcification present;
37. Dissection of neck
Before exploring the neck the thorax and the
skuull should be opened and the viscera removed
After cutting the skin ,the ant cervical strap
muscles are cut and examined
Expose the thyroid cartilage & trachea
Following this ,the tongue ,hyoid bone & the larynx
are removed as unit.
Examine the hyoid bone after separating from
thyroid cartilage & soft tissues removed
See for periosteal haemorrhages & #
.Palpate the sup horn of thyroid cartilage .Examine
lamina of thyroid cartilage & cricoid cartilage for
injury.
Open thyroid cartilage posteriorly & examine
mucosa of larynx
38. Triticeous cartilage are little cartilaginous
nodules embedded in the thyroidhyoid
ligsment .These may be confused with a # of
superior horn of thyroid cartilage
Thank You