Brief information and explanation along with images and example about ParyayaRatnmala Nighantu by Dr. Rashmi Jain - Dravyaguna Department. Along with more info such as Synonyms, Synonyms of Metals, Synonyms of Medicinal Plants, Synonyms of different Gods, Synonyms of several spices and Synonyms of some Ayurveda Acharyas along with many more things.
in ayurvedic pharmacology some drugs have action according to their aura. this aura treat patients in various aspects eg wearing of jems and different stones
Kajjali (mercury- sulphur bond) is one of the basic kalpana in Rasa shastra. Its use in various formulations is well described in rasa text. Although is single use is quite limited in clinical practice, this presentation reveals few of the uses of kajjali in single form.
in ayurvedic pharmacology some drugs have action according to their aura. this aura treat patients in various aspects eg wearing of jems and different stones
Kajjali (mercury- sulphur bond) is one of the basic kalpana in Rasa shastra. Its use in various formulations is well described in rasa text. Although is single use is quite limited in clinical practice, this presentation reveals few of the uses of kajjali in single form.
Rasa sastra is one of the important branch of Ayurveda which deals with mineral and
herbomineral pharmaceutical preparations like kharliya rasayana, parpati rasayana,
kupipakva rasayana and pottali rasayana. Pottali rasayana is one among rasa aushadhi
which is very effective and also known as emergency medicine. Pottali rasayana prepared
by different method. Here we prepare with gandhak drava swedana method. The process of
pottali kalpana is very unique, and from other dosage forms it has qualities like small dose,
very high potency, easy to handle, and maximum shelf life. In Hemagarbha pottali rasa main
drugs are suddha parad, suddha gandhak, tamra bhasma and swarna bhasma which gives
compact form by bhavna with kumari swarwsa. In this article we attempted to described
different methods of preparation and regarding pharmaceutical process of Hemagarbha pottali rasa in detail & Clinical Aspects .
For student of Rasa shastra it is important to be well versed with the knowledge of Paribhasa i.e definitions. As paribhasa itself is vast subject, an attempt is made by these series of presentations to bring the knowledge easily available to learners.
Fundamental principles of bhaishajya kalpana. The word Bhaishajya Kalpana is composed of two words – Bhaishajya and Kalpana. The word Bhaishajya means – relating to Bheshaja (medicine). Kalpana refers to formulation or designing of medicine. There are some fundamental principles, according to which all ayurvedi medicines are prepared.
Ayurveda strongly believes in using drugs with particular tastes in treating diseases. This presentation will help you understand the basics of rasa and its applied aspects in planning treatment protocol.
For a rasa Shastra student its necessary to have knowledge of Parada Bandhas. In this presentation bandhas are explained according to various authors and detailed description is narrated according to Rasa Ratna Samucchaya the most accepted book of Rasa Shastra. I hope this presentation will help the students of Rasa Shastra in having better summarised knowledge of bandhas.
Pathya Kalpana are those formulations in Ayurveda , which are grouped under the category of Ahara/ Food recipies (Kritanna). They have the unique ability to perform the function of both Ahara (If processed simply) and Aushadha (If processed with medications). There are a number of recipes included in Pathya Kalpana . Among them , those which are indicated in samsarjana krama (After Sodhana/ Panchakarma chikitsa ) has been included in this presentation. The presentation aims in the highlighting the general qualties of each Peyadi Krama , their relevance in chikitsa.
Rasa sastra is one of the important branch of Ayurveda which deals with mineral and
herbomineral pharmaceutical preparations like kharliya rasayana, parpati rasayana,
kupipakva rasayana and pottali rasayana. Pottali rasayana is one among rasa aushadhi
which is very effective and also known as emergency medicine. Pottali rasayana prepared
by different method. Here we prepare with gandhak drava swedana method. The process of
pottali kalpana is very unique, and from other dosage forms it has qualities like small dose,
very high potency, easy to handle, and maximum shelf life. In Hemagarbha pottali rasa main
drugs are suddha parad, suddha gandhak, tamra bhasma and swarna bhasma which gives
compact form by bhavna with kumari swarwsa. In this article we attempted to described
different methods of preparation and regarding pharmaceutical process of Hemagarbha pottali rasa in detail & Clinical Aspects .
For student of Rasa shastra it is important to be well versed with the knowledge of Paribhasa i.e definitions. As paribhasa itself is vast subject, an attempt is made by these series of presentations to bring the knowledge easily available to learners.
Fundamental principles of bhaishajya kalpana. The word Bhaishajya Kalpana is composed of two words – Bhaishajya and Kalpana. The word Bhaishajya means – relating to Bheshaja (medicine). Kalpana refers to formulation or designing of medicine. There are some fundamental principles, according to which all ayurvedi medicines are prepared.
Ayurveda strongly believes in using drugs with particular tastes in treating diseases. This presentation will help you understand the basics of rasa and its applied aspects in planning treatment protocol.
For a rasa Shastra student its necessary to have knowledge of Parada Bandhas. In this presentation bandhas are explained according to various authors and detailed description is narrated according to Rasa Ratna Samucchaya the most accepted book of Rasa Shastra. I hope this presentation will help the students of Rasa Shastra in having better summarised knowledge of bandhas.
Pathya Kalpana are those formulations in Ayurveda , which are grouped under the category of Ahara/ Food recipies (Kritanna). They have the unique ability to perform the function of both Ahara (If processed simply) and Aushadha (If processed with medications). There are a number of recipes included in Pathya Kalpana . Among them , those which are indicated in samsarjana krama (After Sodhana/ Panchakarma chikitsa ) has been included in this presentation. The presentation aims in the highlighting the general qualties of each Peyadi Krama , their relevance in chikitsa.
Nasya karma is the special procedure where the aushada (drug) is administered through the nose. How the Different types of Nasya Kalpas act on Different Vyadhis has been described
ANCIENTNESS OF LITERATURE THROUGH NATYASHASTRA.pptxSridevi Vinoth
A Skeletal view of the prominent work of Bharatha's Natyashastra - an Indian Classical Work. It has great association and resemblance to the current era.
Nighantus of Ayurveda help in the right identification of the plant species used in treatment. It is essential to understand the basics of the evolution of Dravyaguna right from the Vedic period to the current era for a Materia Medica scholar in the field of Ayurveda.
Charaka Sutra Maala (Link between Adhyaya to Adhyaya ) help us to Understand the pattern of contents in Samhita.
•The pattern of adhyaayaa’s is as such that the underlying sutra (principle/ Link) is intact.
•Such link can be seen between an adhyaaya & the adhyaaya immediately next to it.
Similar to PPT PARYAYARATNAMALA NIGHANTU.pptx (20)
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
2. INTRODUCTION
One among the texts from Medieval period(8th to 15th century
A. D.)
Author - MADHAVA KARA
Paryaya Ratnamala- 9th cent.
Also known -Ratnamala.
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
3. निरुक्त
• **निघंटु/ Glossary
• निघंटु - निघंटुुः समाह्तं भवन्ति ।**
To collect
• निगूढमर्थमगमयन्तिज्ञापयन्ति इनत निगमुः।
- जो शब्द क
े गुड़ अर्थ को बताए , वह नियम है।
• Which tells about concealed or secert meaning of words is
called as Nigama .
निघंटु
• पयाथयों का संग्रह
• िाम संग्रह
• निघण्टनत शोभनत इनत (शब्द कल्पद्रुम) (which looks beautiful
and shines)
• सभी शब्दो का एक स्र्ाि पर वर्थि
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
4. निघण्टु की परिभाषा
• निक्तयम घण्टयिे एकत्र भाषयिे शब्दाऽिेि् इनत निघण्टु।
एक ही औषनि क
े नवनभन्न पयाथयों का जहा एकत्र वर्थि नकया
जाता है उसे निघण्टु कहते है ।
• आयुवेदो नहतौषनििाम पयाथयों गुर्ानि वर्थिपरुः कोष नवशेषुः ।
आयुवेदों में वनर्थत औषनियों तर्ा उिक
े पयाथयों , गुर् एवम कमथ
का वर्थि जहा नकया जाता है , उसे निघण्टु कहते है ।
• Glossary containing synonyms groups, names , properties and
actions of drugs , plants, animals and minerals or anything that
is administered either as food or medicine to human body.
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
5. निघंटु की प्रिािता
निघंटुिा नबिा वैद्यो नवद्वाि व्याकरर् नबिा ।
अभ्यासेि च िािुषकस्त्रयो हास्यस्य भाजिम।। (रा. नि.)
निघण्टु क
े नबिा वैद्य, व्याकरर् क
े नबिा नवद्वाि तर्ा अभ्यास क
े नबिा
ििुष्क यह तीिों उपहास क
े पात्र बिते है ।
निघण्टुओ में द्रव्य पररचय क
े निए प्रयायों क
े रूप में नवनभन्न
जािकाररयां प्रदाि की जाती है
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
8. AUTHOR
Name - Madhava kara
Son of Indukara / Indrakara
Author of Rogvinishaya - popularly call ‘MADHAVA
NIDANA’
Resident of Silhrada - probably pathaghatta, site of university
of Vikramshila,near Bhagalpur (Bihar )
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
9. Author controversy
Acc. to Lucas - Madhavakara is identical to author of
Madhava nidana.
Acc. to PV. Sharma - Madhavakara was a different person i. e.
2 centuries after Madhavakara, author of Madhava nidana.
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
10. TIME PERIOD
9th Century
Book quoted by Sarvananda - commentator on Amarkosha (
12th Cent ) ; Adhamalla ( 14 th C. )
The book is referred by Chakrapani Dutta - a court physician
of king Nayapaladeva ( 1040 A. D .) in his Chikitsa Samgraha
popularly k/a Chakradatta.
Madhava quotes ref from Vagbhatta .
The book ‘Nidana / Rgvinischaya’ was translated into persian
at the time of haroun - al - Rasid in 8th century .
The drugs - Ahiphena , Bhang as of D. N & RRS (10thC.)
were not described in his work .
Thus ........
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
11. Contents
Not available in our library .
Info - based on the Available .- unclear + missing !
Text available (online) - archive . org
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
12. Presentation
Most concise and direct , almost of sutra type
Synonyms only , No guna karma are mentioned .
No division of the vargas - continuous shlokas.
Descriptive - for the charceriatics of peculiar features of the plant /
drug.
E.g. shankhini .. Peetpushpa laghu lata sugandhini.
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
13. Verses :
1336 shlokas (article)
1758 shlokas (e-Samhita)
Starts from Mangalacharan , followed by the purpose of the text
and way of presentation in 12 line shloka.
Ends with mana paribhasha followed by Granthakara parichaya
.
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
14. Style of presentation
Synonyms of single plant / drug are given in : 1 shlokha,1/2
shlokha , 1/4 shlokha consequently .
1 shlokha (2 lines) = till 102 dravyas in including plant,
animals, metals, salts, panchmahabhuta, classes of men like
servants ect ...
1/2 shlokha (1 line) = till 361 dravyas
1/4 shlokha (1/2 line )= includes 754 factors - body parts,
emotions, disease , plant parts etc.
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
37. Paryaya Muktavali
Paryaya Muktavali is the redacted version of Paryaya
ratnmala- with certain modification in terms of style of
presentation,chapter division and addition of new drugs and
synonyms.
Nighantu of Odisa - prunted in Odiya,bengali and devanagri
script.
But till date - no critical analysis reported on ite structure ,
contents and contribution.
23 Vargs,608 drugs.
Author - Haricharana sen
Resident - Utkala desha (Orissa )
Time period -late 16th - early 17th century
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN
41. Referrences
An Introdction to Nighantus of Ayurveda by D. Shanthkumar Lucas
E- Nighantus
Article - “paryaymuktavali - An unexplored Nighantu of Odisha ,
india .” by Rabindranath Acharya and Deepa K.K.
PARAYAYARATNAMAIA
NIGHANTU - DR. RASHMI JAIN