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Role of nutrition in prevention


           Prof. Muhammad Aslam
            Department of ObGyn
                     LGH, Lahore
 Osteoporosis causes more than 8.9
  million fractures annually worldwide
 Lifetime risk for fracture ~ 30%-40%
 Osteoporosis causes elderly people to
  become bedridden with serious
  complications

        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   2
 20% of people >60 who fracture a hip,
  die within six months to one year
 50% become dependent on family
 Only 30% regain their Independence




        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   3
 Metabolic bone disease characterized
 by low bone mass and micro-
 architectural deterioration of bone
 tissue, leading to enhanced bone
 fragility and a consequent increase in
 fracture risk


        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   4
Normal bone                          Osteoporotic bone


       Postmenopausal Osteoporosis    Prof. Aslam LGH Lahore   5
Normal bone                          Osteoporotic bone

       Postmenopausal Osteoporosis     Prof. Aslam LGH Lahore   6
Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   7
Dual energy X-ray absorptiometry
         (DEXA-Scan)




     Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   8
T Score                         Diagnosis
   +1 to -1                      Normal Bones
  -1 to -2.5                      Osteopenia
-2.5 or lower                    Osteoporosis




   Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   9
 Attainment of peak bone mass ~
  during growth and early adulthood
 Maintaining bone mass ~ in adulthood
 Loss of bone mass ~ with advancing
  age



        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   10
 Genetic
 Endocrine
 Mechanical
 Nutritional




          Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   11
 Ca is the most abundant mineral in
  the body
 99% of Ca is located within the bones
  and teeth
 It supports structural integrity &
  regulates metabolic function

        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   12
 Vit D is critical for Ca absorption ~
  increases Ca absorption by 30-80%
 Vitamin D stimulates bone matrix
  formation and bone maturation
 It also enhances osteoclastic activity



         Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   13
 About 15-20 minutes of sunlight a day
 Vit D is found in fish oils and species
  of fish e.g. salmon, tuna, sardines
 Many milk products, margarines and
  breakfast cereals are fortified with
  vitamin D

         Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   14
 Recently published studies suggest a
 key role for vitamin K nutrition for
 optimisation of bone health




         Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   15
 The prevention of osteoporosis is
 essential for the maintenance of
 health, quality of life, and
 independence in elderly population




         Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   16
 Diet rich in Calcium & Vit. D
 Ca & Vit. D taken as a supplement
 1000 mg Ca/day (premenopausal) &
  1200mg Ca/day (menopausal)
 Vit. D 800 IU/day (menopausal) & 600
  IU/day (premenopausal)

         Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   17
 Yogurt
 Milk
 Cheese
 Cereal
 Whole grains
 Leafy green vegetables
 Sardines & Salmon
 Molasses

        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   18
 Strength-Training has a profound
 effect of strengthening bones




        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   19
Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   20
Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   21
Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   22
 Alendronate (Fosamax®)
 Risedronate (Actonel®)
 Raloxifene (Evista®)
 HRT




        Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   23
 Good evidence to support the effects
  of nutrition on the skeleton
 Ca and vit D are key nutrients for
  bone health ~ effective strategies for
  fracture prevention in the elderly
 Evidence has emerged for a role of vit
  K in bone health. Further data are
  urgently required
         Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   24
Postmenopausal Osteoporosis   Prof. Aslam LGH Lahore   25

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Postmenopausal osteoporosis

  • 1. Role of nutrition in prevention Prof. Muhammad Aslam Department of ObGyn LGH, Lahore
  • 2.  Osteoporosis causes more than 8.9 million fractures annually worldwide  Lifetime risk for fracture ~ 30%-40%  Osteoporosis causes elderly people to become bedridden with serious complications Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 2
  • 3.  20% of people >60 who fracture a hip, die within six months to one year  50% become dependent on family  Only 30% regain their Independence Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 3
  • 4.  Metabolic bone disease characterized by low bone mass and micro- architectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 4
  • 5. Normal bone Osteoporotic bone Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 5
  • 6. Normal bone Osteoporotic bone Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 6
  • 7. Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 7
  • 8. Dual energy X-ray absorptiometry (DEXA-Scan) Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 8
  • 9. T Score Diagnosis +1 to -1 Normal Bones -1 to -2.5 Osteopenia -2.5 or lower Osteoporosis Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 9
  • 10.  Attainment of peak bone mass ~ during growth and early adulthood  Maintaining bone mass ~ in adulthood  Loss of bone mass ~ with advancing age Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 10
  • 11.  Genetic  Endocrine  Mechanical  Nutritional Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 11
  • 12.  Ca is the most abundant mineral in the body  99% of Ca is located within the bones and teeth  It supports structural integrity & regulates metabolic function Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 12
  • 13.  Vit D is critical for Ca absorption ~ increases Ca absorption by 30-80%  Vitamin D stimulates bone matrix formation and bone maturation  It also enhances osteoclastic activity Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 13
  • 14.  About 15-20 minutes of sunlight a day  Vit D is found in fish oils and species of fish e.g. salmon, tuna, sardines  Many milk products, margarines and breakfast cereals are fortified with vitamin D Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 14
  • 15.  Recently published studies suggest a key role for vitamin K nutrition for optimisation of bone health Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 15
  • 16.  The prevention of osteoporosis is essential for the maintenance of health, quality of life, and independence in elderly population Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 16
  • 17.  Diet rich in Calcium & Vit. D  Ca & Vit. D taken as a supplement  1000 mg Ca/day (premenopausal) & 1200mg Ca/day (menopausal)  Vit. D 800 IU/day (menopausal) & 600 IU/day (premenopausal) Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 17
  • 18.  Yogurt  Milk  Cheese  Cereal  Whole grains  Leafy green vegetables  Sardines & Salmon  Molasses Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 18
  • 19.  Strength-Training has a profound effect of strengthening bones Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 19
  • 20. Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 20
  • 21. Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 21
  • 22. Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 22
  • 23.  Alendronate (Fosamax®)  Risedronate (Actonel®)  Raloxifene (Evista®)  HRT Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 23
  • 24.  Good evidence to support the effects of nutrition on the skeleton  Ca and vit D are key nutrients for bone health ~ effective strategies for fracture prevention in the elderly  Evidence has emerged for a role of vit K in bone health. Further data are urgently required Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 24
  • 25. Postmenopausal Osteoporosis Prof. Aslam LGH Lahore 25