Polycythemia Vera is a slow growing blood cancer where the bone marrow produces too many red blood cells, thickening the blood and increasing the risk of blood clots and heart attacks or strokes. It often shows no symptoms for years, though some may feel dizzy, tired, weak, or have itchy skin or shortness of breath. Testing can identify high blood cell counts and bone marrow exams are used to diagnose. While it can occur at any age, it is more common in older men and is caused by a mutation of the JAK2 gene. Treatment focuses on managing hematocrit levels through phlebotomy, medication and cytoreductive therapy to control symptoms and prevent life-threatening complications if left untreated

2. Polycythemia Vera (Myeloproliferative neoplasm) is a slow growing blood cancer in
which the bone marrow produces high number of red blood cells, which thickens
the blood leading to blood clots resulting heart attack or stroke. Globally three in
every one lakh people per year are affected. Many people suffering usually don’t
show any signs and symptoms for years although physically they might have some
warning signs like dizziness or feeling tired and weak, itchy skin, shortness of
breath etc. It can be identified in a routine blood test that shows high number of
blood cells, further diagnosis include erythropoietin level test, Bone marrow
examination etc. PV occurs at any age but more common in men than women at a
median age of more than 60 years. The main cause of PV seems to be mutation of
Janus kinase 2 gene in the body.
Polycythemia Vera can be controlled by returning hematocrit level to normal levels.
Therapeutically Asprin is beneficial according to ECLAP study. Phlebotomy and
cytoreductive therapy is also recommended. It can be a life threatening if not
treated. Present literary based study deals with the causes, detection and
management of this disease through authentic sources.