This document summarizes the political history of herbal medicine in the United States from colonial times to the early 20th century. It describes how Native American and African American herbal traditions influenced early settlers. Herbalists, often women, were the primary caregivers initially. Regular physicians trained in Europe also practiced. The Thomsonian and Eclectic movements popularized herbalism but lost ground as allopathic medicine became the dominant model after the 1910 Flexner Report. This established medical schools and practice standards, favoring allopathy. While some herbal practices continued underground, goldenseal adulteration and conservation issues emerged as its popularity grew again later.