Plegable biologia molecular
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This document discusses DNA transcription and folding. It summarizes two studies: one that found a genetic mutation called MAK that causes blindness by disrupting protein production in retinal cells, and another that identified a mechanism by which cigarette smoke can increase fibronectin deposition in lung tissue of COPD patients by activating the NF-kB protein complex. The document concludes that such studies are important for advancing medical understanding and developing new clinical therapies.
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multiplication, and relevance in skin biology.
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This document discusses several studies on monogenic disorders and their potential medical applications. It first introduces monogenic disorders as involving mutations in a single gene, which can be inherited or spontaneous. Two studies are then summarized: one finding that brain stimulation may help restore breathing capacity in Duchenne muscular dystrophy patients by activating the diaphragm muscle, and another observing changes in mucus protein structure in cystic fibrosis patients that could provide insight into treatment. The document concludes that these studies bring researchers closer to potential treatments for currently incurable genetic diseases and improve patients' quality of life.
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This document contains summaries of 5 presentations on the topic of branching morphogenesis during lung and organ development.
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Donna Milgram founded a national institute to foster female success in STEM fields. In an interview, she discusses the institute's mission to promote the potential of women in STEM and ensure they have a prominent place in science and technology. The institute aims to encourage and promote women in science, engineering, and technology through initiatives like promoting gender equality in Europe and collecting data on gender trends in STEM.
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This document provides an introduction to transhumanism including definitions, goals, and an agenda covering various topics. It defines transhumanism as the belief that humans can evolve beyond limitations through science and technology. The agenda covers gene editing using CRISPR-Cas9, applications in diseases like sickle cell and blindness, brain-computer interfaces, anti-aging research, nanotechnology, and ethical issues. Experts discuss progress in areas like reversing age-related vision loss and potential for dramatically extending lifespan. Philosophical questions around human enhancement and what it means to be human are also raised.
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This document provides an introduction to biotechnology. It defines biotechnology as the use of living cells, including microorganisms, plant cells, and animal cells, for the benefit of humanity. Key areas of biotechnology discussed include agriculture, food, industry, biofuels, cosmetics, pharmaceuticals, and waste utilization. The document outlines several important techniques in biotechnology such as genetic engineering, gene therapy, bioinformatics, restriction enzymes, reverse transcriptase, polymerase chain reaction, genetic fingerprinting, cloning, and genetically modified plants.
CV Jan 2016
MinHee K. Ko has extensive research experience in ocular diseases including uveitis, retinal ischemia, glaucoma, and neurodegenerative diseases. She has a Ph.D. in pathobiology from USC and has held postdoctoral positions focused on immune-based therapies for neurodegenerative disorders and ocular pathology. Her research experience includes developing novel therapeutics for glaucoma using animal models and examining innate immune-mediated photoreceptor cell death in uveitis models.
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This document summarizes several research studies on genetics and the human genome. It discusses how genome research allows for understanding of genetic backgrounds and disease susceptibility. One study identified that activating the NOTCH and AKT genes can trigger cholangiocarcinoma by reprogramming mature liver cells into bile duct cells. Researchers are exploring gene therapy and antibody treatments targeting these genes to treat cholangiocarcinoma. While much remains to be learned, these studies provide insights into cancer development and new therapeutic approaches.
RESEARCHERS MAP SIGNIFICANT OF FUNCTIONAL SEQUENCES OF MOUSE GENOME AND ACTIV...
This document summarizes several research studies on genetics and the human genome. It discusses how genome research allows for understanding of genetic backgrounds and disease susceptibility. One study identified that activating the NOTCH and AKT genes can trigger cholangiocarcinoma by reprogramming mature liver cells into bile duct cells. Researchers are exploring gene therapy and antibody treatments to target these disease-causing genes. While much remains to be learned, studies of the genome are providing insights into disease development and new treatment approaches.
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This document summarizes several research studies on genetics and the human genome. It discusses how genome research allows for understanding of genetic backgrounds and disease susceptibility. One study identified that activating the NOTCH and AKT genes can trigger cholangiocarcinoma by reprogramming mature liver cells into bile duct cells. Researchers are exploring gene therapy and antibody treatments to target these disease-causing genes. While much remains to be learned, this research enhances understanding of cancer development and provides potential avenues for new therapies.
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This document summarizes key findings from recent research on the human genome and cholangiocarcinoma. The research identified that activating the NOTCH and AKT genes can cause liver cells to transform into cholangiocarcinoma cancer cells. While it was previously believed that only stem cells could change cell types, this research showed that mature liver cells can be reprogrammed to become another cell type. Understanding the molecular origins of this disease may help develop new antibody therapies to treat cholangiocarcinoma. Overall, the study provides important insights into how cancers can develop and highlights the medical utility of genome research.
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Plegable biomol
Researchers discovered a protein involved in cancer metastasis that also inhibits two proteins linked to neurodegenerative diseases. They also identified a non-coding RNA called INXS that modulates a gene important for apoptosis. In mouse studies, tumors treated with INXS decreased in size compared to controls. Both studies could help develop future cancer treatments by inhibiting metastasis genes or activating apoptosis through increasing INXS expression.
Cv feb 2016
• Extensive research experience in ocular translational research in uveitis, retinal ischemia, glaucoma, neurodegenerative disease, and retrocorneal fibrosis.
• In-depth knowledge and wet laboratory experience from basic science to translational research: Cellular/molecular biology, Microbiology, Pathology, Biochemistry, Neuroimmunology, in vivo rodent translational research.
• Independent self-motivated scientist working for multiple research projects from perform experiments, analyze data, generate manuscripts, grant, or oral presentations
• Experience in managing lab, collaboration, supervising/mentoring students and fellows.
nuclear pore complex and function nucleus
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Biology, genetics, nanotechnology, neuroscience, materials science, biotech, ...
Over the past two years I've done a lot of interesting research which I've decided to aggregate. My research pertains to the following: Biology, Genetics, Nanotechnology, Neuroscience, Materials Science, Biotechnology, Chemical Engineering, All Things 3-D, Super Computing, Quantum Physics, Energy, Design, & Sustainability.
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Plegable biologia molecular
- 1. DNA TRANSCRIPTION Luis Carlos Fuentes Acosta Id: 00172019 Molecular Biology Universidad Pontificia Bolivaria.
- 2. Folding
- 3. Folding
- 4. INTRODUCTION. These studies with transcription and have been very valuable for the contribution of specific genetic level studies of disease explained in the folding
- 5. U. Iowa research team finds new genetic cause of blindingeyedisease
- 7. The researchers generated induced pluripotent stem cells from skin cells of the patient and self-convinced these immature cells to become retinal tissue
- 8. It was found that the mutation MAK, which involves inserting a large piece of DNA into the MAK gene, disrupts the gene so that cells of the retina loses the ability to make the longer version of the protein MAK .
- 9. OBSERVATION This study does give hope to patients with this disease as it achieves control bystem cells
- 10. Researchers identify mechanism underlying COPD disease persistence after smoking cessation
- 11. The aim was to examine whether cigarette smoke extract alters the ECM deposited primary human lung fibroblasts, and if smoke can alter ECM-induced proliferation and cytokine release
- 12. The researchers examined the response of human lung tissue from donors withand without EPOC to cigarette smoke extract.
- 13. Increased deposition of fibronectin was attenuated by an inhibitor of NF-kB (a protein complex that controls transcription of DNA) in the tissue of EPOC.
- 14. OBSERVATION It is a great study because it shows from a histological point of view changes from the smoke in EPOC patients which might help in the clinic
- 15. MedicalUtility
- 16. These studies are very important in modern medicine because they help to develop efficient methods in terms of clinical management
- 17. Also manage to make some progress in therapy to patients because they areable to discover the initial problem and where in this.
- 18. These new findings help to give more life expectancy of the patient in case of afatal disease, and should not be helping to increase the welfare
- 19. BIBLIOGRAPHY U. Iowa research team finds new genetic cause of blindingeyedisease, Todd Scheetz, Sheffield Val, DeLucaAdán, Hoffman y Rebecca Jeremy Johnston, de la interfaz de usuario de Jacobson y Samuel of eyed Scheie, august 9 de 2011, in pubmed. Researchers identify mechanism underlying COPD disease persistence after smoking cessation, American Thoracic Society, July 27, 2011, in pubmed.