Plasma protein classification 1 albumin
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Serum albumin is the most abundant protein in blood plasma and is produced in the liver. It normally constitutes about 60% of human plasma proteins. Serum albumin helps regulate blood volume and acts as a carrier for substances like hormones, calcium ions, and bilirubin. Low or high albumin levels can be caused by conditions like liver disease, malnutrition, or dehydration. Albumin is measured from serum, plasma, or plain blood samples and a normal level in adults is 3.5-5 g/dL.
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The relationship between serum albumin concentration and sarcopenia
Lower serum albumin levels are associated with greater loss of muscle mass and strength over time in older adults according to some studies. The Health ABC study found that lower serum albumin was related to greater loss of appendicular skeletal muscle mass over 5 years. The LASA study also found lower serum albumin to be associated with weaker muscle strength and greater decline in strength over 3 years. However, the MrOS study found only modest and inconsistent trends between serum albumin and loss of muscle mass and function in elderly men. Overall, the relationship between serum albumin and sarcopenia requires more research.
Plasma protiens and their clinical significance
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Plasma proteins
The document discusses the proteins found in human plasma. It describes how plasma proteins can be separated into fractions including albumin, globulins, fibrinogen, and others. Specific plasma proteins are then discussed in more detail, including their structure, function, concentration in plasma, and clinical significance. Albumin, the most abundant plasma protein, is highlighted for its roles in maintaining colloidal osmotic pressure and transporting various substances through the bloodstream.
Plasma proteins class
This document discusses plasma proteins and their functions. Some key points:
- Plasma is the liquid component of blood that remains after red and white blood cells are removed by centrifugation. It makes up 55-60% of total blood volume.
- Serum is similar to plasma but lacks coagulation factors as it is produced when blood is allowed to clot.
- The main plasma proteins are albumin, globulins, and fibrinogen. Albumin maintains osmotic pressure while globulins are involved in transport and immunity.
- Electrophoresis and immunoelectrophoresis can separate plasma proteins based on their electrical charge and antigenic properties. Specific acute phase proteins increase during inflammation.
Albumin and albumin & globin ratio
albumin role , synthesis, function, factor affect, increase in , decrease in use of a\g ratio how calculate a\g ratio. why need,
Plasma proteins
This document discusses plasma proteins, including their functions, measurement, classification, and major types. It notes that plasma contains thousands of proteins like albumin, globulins, antibodies, enzymes, and transport proteins. Total plasma protein concentration is normally 7-7.5 g/dL. Major classes of globulins include alpha, beta, and gamma globulins. Key plasma proteins discussed in more detail include albumin, immunoglobulins, haptoglobin, transferrin, ceruloplasmin, alpha-1 antitrypsin, and alpha-2 macroglobulin.
Plasma protein by Dr. Rahul Singh Thakur
This document discusses plasma proteins in the blood. It defines plasma proteins and explains that they are mainly synthesized by the liver and lymphoid tissues. The major types of plasma proteins are described including albumin, globulins, fibrinogen, and others. The key functions of plasma proteins are coagulation, defense mechanisms, maintenance of oncotic pressure, acid-base balance regulation, and viscosity of blood. The process of plasmapheresis, which separates plasma from blood, is also summarized.
Plasma proteins
This document summarizes plasma proteins and immunoglobulins. It discusses that plasma is composed of water, electrolytes, nutrients, wastes, and plasma proteins. The major plasma proteins include albumin, globulins, and immunoglobulins. Albumin is the most abundant plasma protein and serves important functions like transport and maintenance of osmotic pressure. Globulins include acute phase proteins, ceruloplasmin, transferrin, and others. Immunoglobulins are antibody proteins that are involved in immune responses through antigen binding and activating effector functions. The five major immunoglobulin classes are IgG, IgA, IgM, IgD, and IgE.
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The relationship between serum albumin concentration and sarcopenia
Lower serum albumin levels are associated with greater loss of muscle mass and strength over time in older adults according to some studies. The Health ABC study found that lower serum albumin was related to greater loss of appendicular skeletal muscle mass over 5 years. The LASA study also found lower serum albumin to be associated with weaker muscle strength and greater decline in strength over 3 years. However, the MrOS study found only modest and inconsistent trends between serum albumin and loss of muscle mass and function in elderly men. Overall, the relationship between serum albumin and sarcopenia requires more research.
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its an extensive presentation about plasma protiens and their clinical significance for people studying medicine and biochemistry.
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Plasma proteins class
This document discusses plasma proteins and their functions. Some key points:
- Plasma is the liquid component of blood that remains after red and white blood cells are removed by centrifugation. It makes up 55-60% of total blood volume.
- Serum is similar to plasma but lacks coagulation factors as it is produced when blood is allowed to clot.
- The main plasma proteins are albumin, globulins, and fibrinogen. Albumin maintains osmotic pressure while globulins are involved in transport and immunity.
- Electrophoresis and immunoelectrophoresis can separate plasma proteins based on their electrical charge and antigenic properties. Specific acute phase proteins increase during inflammation.
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albumin role , synthesis, function, factor affect, increase in , decrease in use of a\g ratio how calculate a\g ratio. why need,
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Plasma proteins
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Total plasma protein
This document provides information on the colourimetric method for determining total plasma proteins. It begins with definitions of key terms like colourimetry and blank. It then discusses the principle that absorbance is directly proportional to concentration and path length. The document provides details on the types and functions of plasma proteins like albumins and globulins. It discusses the biuret reaction used to colorimetrically determine total plasma proteins and provides the normal ranges and clinical significance of variations in plasma protein levels.
PLASMA PROTEINS
This document summarizes plasma proteins. It describes that plasma is the liquid portion of blood that remains after clotting or centrifugation. The major plasma proteins are albumin, globulins, and fibrinogen. Albumin is synthesized in the liver and serves important transport and homeostatic functions, while globulins include acute phase proteins and immunoglobulins. Several specific plasma proteins are also discussed in detail, including their structure, function, clinical significance, and role in conditions like Wilson's disease.
blood plasma protein
- The document discusses the composition and properties of blood plasma proteins. It describes the major classes of plasma proteins including albumins, globulins, enzymes, and lipoproteins.
- Specific globulin proteins are examined in more detail, such as their structure, function, and clinical significance. Alpha-1 antitrypsin and alpha-2 macroglobulin are protease inhibitors, while haptoglobin binds free hemoglobin.
- Immunoglobulins are antibody proteins that are divided into five classes based on their heavy chain constant region: IgG, IgA, IgM, IgD, and IgE. They have a basic Y-shaped structure composed of two heavy and two light chains that allows for antigen binding
Blood 2 functions of plasma proteins
Plasma proteins serve several essential functions: (1) They maintain colloid osmotic pressure and electrolyte balance; (2) Transport nutrients, waste, hormones, and drugs; (3) Regulate blood clotting through proteins like fibrinogen. The major plasma proteins are albumin, globulins, and fibrinogen. Albumin maintains colloid osmotic pressure while globulins are involved in immune defense and transport of metals. Electrophoresis and chromatography are common methods used to separate and analyze the different plasma protein fractions.
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It's is about the basic biochemistry of liver and blood. And helpful in homeworks.And will be very useful for the basic knowledge.
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The document summarizes plasma proteins and their functions. It discusses that normal plasma proteins are 6-8 g/dl and consist of albumin, globulins, and fibrinogen. The main fractions of plasma proteins - albumin, alpha, beta, and gamma globulins - are described. Key plasma proteins like albumin, ceruloplasmin, haptoglobin, and C-reactive protein are explained in terms of their structure, function, and clinical significance. Acute phase proteins that increase or decrease during inflammation are also outlined.
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Plasma proteins play important roles in the body such as being diagnostic biomarkers and supporting cell growth. Analysis identified several plasma proteins encoded by the X chromosome including APXL protein and immunoglobulin binding protein 1. Most of these proteins have few isoforms and around 42% show single nucleotide polymorphisms, suggesting a risk of mutations. Post-translational modifications were limited to phosphorylation and the subcellular localization of many remains unknown, though some were found in unexpected areas like the nucleus.
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Plasma proteins
Plasma contains proteins that perform important functions like maintaining pH and colloid osmotic pressure. The most abundant protein is albumin, which makes up around 75% of plasma's colloid osmotic pressure. Other major classes of plasma proteins include globulins such as alpha-1 globulins containing thyroxine-binding globulin and alpha-1-antitrypsin; alpha-2 globulins containing ceruloplasmin and haptoglobin; beta-globulins containing transferrin; and gamma-globulins which are antibodies. These proteins transport substances like vitamins, minerals, lipids, and hormones or help in coagulation, immune defense, and acute phase responses.
Plasma proteins
The document discusses several major plasma proteins including albumin, globulins, fibrinogen, and acute phase proteins. Albumin is the most abundant plasma protein synthesized by the liver and helps maintain blood volume and transport substances through the bloodstream. The main globulin proteins are alpha, beta, and gamma globulins which have roles in transport and immunity. Fibrinogen aids in blood clotting. C-reactive protein and ceruloplasmin are acute phase proteins that increase during inflammation.
Plasma protein
Plasma proteins are proteins found in blood plasma after removing cells. The main plasma proteins are albumins, immunoglobulins, and fibrinogens. Albumins make up 60% of plasma proteins and maintain fluid balance. Immunoglobulins like IgG, IgA, IgM, IgE, and IgD make up 18% and are involved in immunity. Fibrinogens make up 4% and are involved in blood clotting. Plasma proteins are synthesized mostly in the liver and have important functions like fluid balance, transport, immunity, and coagulation.
Plasma proteins
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PP-01: Role of Plasma Proteins in Health and diseases
Centrifugation is used to separate blood components by density. Plasma, which makes up 55% of blood volume, is the pale liquid found at the top after centrifugation. It contains water, proteins, electrolytes, nutrients, waste products, and gases. The two major classes of plasma proteins are albumin and globulins. Albumin maintains colloid osmotic pressure and transports molecules like hormones, fatty acids, and drugs throughout the body. Low albumin can cause edema. Globulins include immune proteins and transport proteins. Common plasma tests measure total protein, albumin, globulin, and albumin/globulin ratios to assess health conditions.
Plasma protein
This document discusses plasma proteins and their roles in health and disease. It provides examples of plasma proteins that are important biomarkers for specific conditions, such as ceruloplasmin for Wilson's disease and albumin for nephrotic syndrome. The document defines key plasma proteins like albumin and immunoglobulins. It also discusses acute phase reactants and their roles in inflammation. Specific conditions like Wilson's disease and Menkes disease are examined in terms of the plasma proteins involved and how deficiencies can cause disease.
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This document discusses plasma proteins. It begins by stating that plasma consists of various components including proteins. The concentration of total protein in human plasma is approximately 6.0-8.0 g/dL, with proteins making up the major part of plasma solids. The proteins include simple proteins as well as conjugated proteins like glycoproteins and lipoproteins. Major plasma proteins can be separated into albumin, globulins, and fibrinogen using salting-out or electrophoresis methods. The document then focuses on describing specific plasma proteins in detail, including their structure, function, normal levels, and clinical significance.
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Plasma proteins
Plasma is the liquid portion of blood that remains after red and white blood cells are removed. It contains water, salts, enzymes, antibodies, and proteins. The major plasma proteins are albumin, globulins, and fibrinogen. Albumin is the most abundant plasma protein and plays important roles in maintaining colloidal osmotic pressure and transporting molecules like fatty acids, hormones, and bilirubin. Low albumin levels can cause edema. Globulins are divided into alpha, beta, and gamma classes, and include proteins like ceruloplasmin, transferrin, C-reactive protein, and haptoglobin that have clinical significance as markers of disease states.
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This document provides information on the colourimetric method for determining total plasma proteins. It begins with definitions of key terms like colourimetry and blank. It then discusses the principle that absorbance is directly proportional to concentration and path length. The document provides details on the types and functions of plasma proteins like albumins and globulins. It discusses the biuret reaction used to colorimetrically determine total plasma proteins and provides the normal ranges and clinical significance of variations in plasma protein levels.
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This document summarizes plasma proteins. It describes that plasma is the liquid portion of blood that remains after clotting or centrifugation. The major plasma proteins are albumin, globulins, and fibrinogen. Albumin is synthesized in the liver and serves important transport and homeostatic functions, while globulins include acute phase proteins and immunoglobulins. Several specific plasma proteins are also discussed in detail, including their structure, function, clinical significance, and role in conditions like Wilson's disease.
blood plasma protein
- The document discusses the composition and properties of blood plasma proteins. It describes the major classes of plasma proteins including albumins, globulins, enzymes, and lipoproteins.
- Specific globulin proteins are examined in more detail, such as their structure, function, and clinical significance. Alpha-1 antitrypsin and alpha-2 macroglobulin are protease inhibitors, while haptoglobin binds free hemoglobin.
- Immunoglobulins are antibody proteins that are divided into five classes based on their heavy chain constant region: IgG, IgA, IgM, IgD, and IgE. They have a basic Y-shaped structure composed of two heavy and two light chains that allows for antigen binding
Blood 2 functions of plasma proteins
Plasma proteins serve several essential functions: (1) They maintain colloid osmotic pressure and electrolyte balance; (2) Transport nutrients, waste, hormones, and drugs; (3) Regulate blood clotting through proteins like fibrinogen. The major plasma proteins are albumin, globulins, and fibrinogen. Albumin maintains colloid osmotic pressure while globulins are involved in immune defense and transport of metals. Electrophoresis and chromatography are common methods used to separate and analyze the different plasma protein fractions.
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It's is about the basic biochemistry of liver and blood. And helpful in homeworks.And will be very useful for the basic knowledge.
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The document summarizes plasma proteins and their functions. It discusses that normal plasma proteins are 6-8 g/dl and consist of albumin, globulins, and fibrinogen. The main fractions of plasma proteins - albumin, alpha, beta, and gamma globulins - are described. Key plasma proteins like albumin, ceruloplasmin, haptoglobin, and C-reactive protein are explained in terms of their structure, function, and clinical significance. Acute phase proteins that increase or decrease during inflammation are also outlined.
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Plasma proteins play important roles in the body such as being diagnostic biomarkers and supporting cell growth. Analysis identified several plasma proteins encoded by the X chromosome including APXL protein and immunoglobulin binding protein 1. Most of these proteins have few isoforms and around 42% show single nucleotide polymorphisms, suggesting a risk of mutations. Post-translational modifications were limited to phosphorylation and the subcellular localization of many remains unknown, though some were found in unexpected areas like the nucleus.
Albumin presintation
This document discusses albumin, the major protein in human plasma. Albumin is synthesized in the liver and plays important roles in transporting molecules through the blood and maintaining fluid balance. A serum albumin test measures the levels of this protein, which are normally between 3.4-5.4 g/dL. Lower levels can indicate liver or kidney disease, while higher levels may result from dehydration or fluid infusion. Certain drugs and medical conditions can also impact albumin levels. Risks of blood collection for albumin testing are generally minor.
Plasma proteins
Plasma contains proteins that perform important functions like maintaining pH and colloid osmotic pressure. The most abundant protein is albumin, which makes up around 75% of plasma's colloid osmotic pressure. Other major classes of plasma proteins include globulins such as alpha-1 globulins containing thyroxine-binding globulin and alpha-1-antitrypsin; alpha-2 globulins containing ceruloplasmin and haptoglobin; beta-globulins containing transferrin; and gamma-globulins which are antibodies. These proteins transport substances like vitamins, minerals, lipids, and hormones or help in coagulation, immune defense, and acute phase responses.
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The document discusses several major plasma proteins including albumin, globulins, fibrinogen, and acute phase proteins. Albumin is the most abundant plasma protein synthesized by the liver and helps maintain blood volume and transport substances through the bloodstream. The main globulin proteins are alpha, beta, and gamma globulins which have roles in transport and immunity. Fibrinogen aids in blood clotting. C-reactive protein and ceruloplasmin are acute phase proteins that increase during inflammation.
Plasma protein
Plasma proteins are proteins found in blood plasma after removing cells. The main plasma proteins are albumins, immunoglobulins, and fibrinogens. Albumins make up 60% of plasma proteins and maintain fluid balance. Immunoglobulins like IgG, IgA, IgM, IgE, and IgD make up 18% and are involved in immunity. Fibrinogens make up 4% and are involved in blood clotting. Plasma proteins are synthesized mostly in the liver and have important functions like fluid balance, transport, immunity, and coagulation.
Plasma proteins
This document discusses plasma proteins and the differences between blood, plasma, and serum. It outlines the major plasma proteins including albumin, globulins, fibrinogen, transport proteins, immunoglobulins, and clotting factors. Albumin is the most abundant plasma protein and serves important functions like maintaining osmotic pressure and transporting substances through the bloodstream. Globulins include alpha-1 proteins, alpha-2 proteins, and beta and gamma globulins which are involved in processes like iron transport, protease inhibition, and immunity. Acute phase proteins either increase or decrease during inflammatory responses.
PP-01: Role of Plasma Proteins in Health and diseases
Centrifugation is used to separate blood components by density. Plasma, which makes up 55% of blood volume, is the pale liquid found at the top after centrifugation. It contains water, proteins, electrolytes, nutrients, waste products, and gases. The two major classes of plasma proteins are albumin and globulins. Albumin maintains colloid osmotic pressure and transports molecules like hormones, fatty acids, and drugs throughout the body. Low albumin can cause edema. Globulins include immune proteins and transport proteins. Common plasma tests measure total protein, albumin, globulin, and albumin/globulin ratios to assess health conditions.
Plasma protein
This document discusses plasma proteins and their roles in health and disease. It provides examples of plasma proteins that are important biomarkers for specific conditions, such as ceruloplasmin for Wilson's disease and albumin for nephrotic syndrome. The document defines key plasma proteins like albumin and immunoglobulins. It also discusses acute phase reactants and their roles in inflammation. Specific conditions like Wilson's disease and Menkes disease are examined in terms of the plasma proteins involved and how deficiencies can cause disease.
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This document discusses plasma proteins. It begins by stating that plasma consists of various components including proteins. The concentration of total protein in human plasma is approximately 6.0-8.0 g/dL, with proteins making up the major part of plasma solids. The proteins include simple proteins as well as conjugated proteins like glycoproteins and lipoproteins. Major plasma proteins can be separated into albumin, globulins, and fibrinogen using salting-out or electrophoresis methods. The document then focuses on describing specific plasma proteins in detail, including their structure, function, normal levels, and clinical significance.
Serum proteins
Serum proteins are the most abundant compounds in blood after removing cells. They serve many important functions including acting as building blocks, enzymes, hormones, antibodies, and helping maintain acid-base balance and osmotic pressure. The major serum proteins measured are albumin and globulins, with albumin primarily made in the liver and globulins including antibodies and transport proteins. Abnormal levels can provide clues about conditions affecting the liver, kidneys, nutrition, infections, and more.
Plasma proteins
The plasma is the liquid portion of blood that contains proteins like albumins, globulins, fibrinogen, and immunoglobulins. The main classes of globulins are alpha, beta, and gamma globulins. Immunoglobulins, also called antibodies, are gamma globulins that recognize and bind to antigens with high specificity. The five major classes of immunoglobulins in humans are IgG, IgM, IgA, IgD, and IgE, which have different structures and functions. Multiple myeloma is a cancer of plasma cells that results in overproduction of a single immunoglobulin class.
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Plasma proteins
Plasma is the liquid portion of blood that remains after red and white blood cells are removed. It contains water, salts, enzymes, antibodies, and proteins. The major plasma proteins are albumin, globulins, and fibrinogen. Albumin is the most abundant plasma protein and plays important roles in maintaining colloidal osmotic pressure and transporting molecules like fatty acids, hormones, and bilirubin. Low albumin levels can cause edema. Globulins are divided into alpha, beta, and gamma classes, and include proteins like ceruloplasmin, transferrin, C-reactive protein, and haptoglobin that have clinical significance as markers of disease states.
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JAUNDICE & LIVER FUNCTION TESTS
1. Liver function tests measure enzymes and proteins to evaluate liver health and detect liver damage or disease.
2. Elevated bilirubin, ALT, AST, alkaline phosphatase, and prolonged prothrombin time indicate potential liver issues like hepatitis, cirrhosis, or obstruction.
3. Abnormal albumin, globulin, ammonia, ferritin, and lactate dehydrogenase levels also suggest liver or other organ dysfunction and are used to diagnose and monitor conditions.
Albumin
Albumin is the most abundant plasma protein, accounting for about half of plasma protein mass. It serves important functions such as maintaining colloid osmotic pressure and transporting compounds like fatty acids, drugs, and metals. Albumin is synthesized primarily by the liver and has a half-life of 15-19 days. Low albumin levels can result from decreased synthesis, increased losses, or redistribution to extravascular spaces. Key tests for albumin involve dye-binding or immunological methods, with reference intervals of 3.5-5.2 g/dL in healthy adults.
BLOOD PLASMA
Plasma is the liquid component of blood that holds the blood cells in suspension. It makes up 55% of the blood's total volume and is mostly composed of water (92%) and dissolved proteins (8%). Plasma carries nutrients, hormones, carbon dioxide, and oxygen to tissues and transports waste products away from tissues. It plays a vital role in maintaining electrolyte balance and protects the body from infection. Plasma is separated from blood cells when a tube of blood is spun in a centrifuge.
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Plasma is the liquid component of blood that remains after red blood cells, white blood cells, and platelets are removed. It is composed primarily of water, proteins, electrolytes, nutrients, wastes, and blood gases. The major proteins in plasma include albumin, globulins, and immunoglobulins. Albumin maintains osmotic pressure and transports molecules like hormones, fatty acids, and bilirubin throughout the body. Globulins such as alpha-1 antitrypsin regulate enzymes and transport metals. Immunoglobulins act as antibodies to help fight infection.
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The document discusses liver function tests (LFTs), which are noninvasive tests used to screen for and identify types of liver dysfunction. LFTs measure levels of enzymes and proteins to assess liver damage, obstruction of bile flow, and synthetic function. Elevations in different markers can indicate conditions like hepatitis, cirrhosis, and cancer. While normal LFTs don't rule out disease, abnormal results require further clinical examination to diagnose a liver disorder. The document then describes several specific LFT markers and what they indicate, such as bilirubin for hemolysis or obstruction and ALT/AST for hepatocellular injury.
All Medical Tests Description.pdf
This document provides information on various blood tests including their names, definitions, and normal ranges. It covers complete blood count tests, liver function tests, kidney function tests, lipid profiles, blood sugar tests, thyroid function tests, cardiac markers, tumor markers, tests for arthritis, and semen analysis. The tests measure important components of blood and other bodily fluids to screen for conditions, diseases, and overall health status.
pdffile.co_.in-all-blood-test-name-list.pdf
This document provides information on various blood tests, including their names, definitions, and normal ranges. It covers complete blood count tests, liver function tests, kidney function tests, lipid profiles, blood sugar tests, urine tests, cardiac blood tests, thyroid function tests, and blood tests for infertility. The tests measure important components of blood and other bodily fluids to screen for conditions, monitor health, and diagnose issues.
Blood Tests.pdf
This document provides information on various blood tests, including their names, definitions, and normal ranges. It covers complete blood count tests, liver function tests, kidney function tests, lipid profiles, blood sugar tests, thyroid function tests, cardiac markers, tumor markers, tests for arthritis, and semen analysis. The tests measure important components of blood and other bodily fluids to screen for conditions, diseases, and overall health and provide essential information to medical practitioners.
all medical test description.pdf
This document provides information on various blood tests, including their names, definitions, and normal ranges. It covers complete blood count tests, liver function tests, kidney function tests, lipid profiles, blood sugar tests, urine tests, cardiac blood tests, thyroid function tests, and blood tests for infertility. The tests measure important components of blood and other bodily fluids to screen for conditions, monitor health, and diagnose issues.
Plasma proteins.pptx
This document discusses plasma proteins and their functions. It outlines that plasma proteins include albumin, globulins, acute phase proteins, and immunoglobulins. Albumin is the major plasma protein and serves important osmotic, transport, nutritive, and buffering functions. Globulins contain proteins like alpha-1 antitrypsin, alpha-2 macroglobulin, haptoglobin, ceruloplasmin, and transferrin. Acute phase proteins increase during infection or inflammation and include C-reactive protein.
LIVER FUNCTIONS TESTS -2-
This document discusses various biomarkers used in the diagnosis of liver disease. It describes how bile salts facilitate fat absorption and are excreted in urine during cholestasis. Primary and secondary bile salts are produced in the liver and intestines. Increased renal excretion of bile salts occurs during cholestasis. Liver enzymes like ALT, AST, ALP, GGT and 5-nucleotidase reflect hepatocyte damage and cholestasis. Elevated ALT and AST indicate hepatocellular injury. Increased ALP, GGT and 5-nucleotidase suggest cholestasis. Prothrombin time is prolonged in liver dysfunction due to decreased synthesis of clotting factors. Albumin and globulin
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Plasma protein classification 1 albumin
- 2. The most well known albumin is serum albumin. Serum albumin is the most abundant blood plasma protein and is produced in liver. The human version is human serum albumin and it normally constitutes about 60%of human plasma protein.
- 4. Serum albumins are important in regulating blood volume. They also serve as carriers for low water solubility . Low albumin (hypoalbumineria)may be caused by liver disease ,nephritic syndrome, syndrome ,burns ,malnutrition,late pregnancy,etc………
- 6. High albumin (hyperalbumineria)is almost always caused by dehydration. In some cases of retinol (vitamin A)deficiency the albumin level can become raised to high normal values(eg:4.9g/dL). Normal range of human serum albumin in adult 3.5 to 5g/dL . For children less than 3 years of age normal range is 2.5 to 5.5g/dL.
- 7. Maintain oncotic pressure. Transport thyroid hormone. Transport other hormone ,that are fat soluble. Transport conjugated bilirubin. Competitively binds calcium ions. Buffer PH
- 8. Albumin can be measured in serum (yellow top tube),plain tube with no additives (red top tube)or heparin plasma (green top tube). The reference interval is 36 -52g/l . One of the method used is bromocresol green on a Roche modular or olympus AU2700 analyser.
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