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The Plasma Membrane  - Gateway to the Cell copyright cmassengale
Photograph of a Cell Membrane copyright cmassengale
Cell Membrane ,[object Object],copyright cmassengale
Homeostasis ,[object Object],[object Object],[object Object],copyright cmassengale
Functions of Plasma Membrane ,[object Object],[object Object],[object Object],[object Object],copyright cmassengale
Functions of Plasma Membrane ,[object Object],[object Object],[object Object],copyright cmassengale
Structure of the Cell Membrane copyright cmassengale
Phospholipids Cholesterol Proteins ( peripheral and integral) Carbohydrates (glucose) Membrane Components copyright cmassengale
copyright cmassengale
Phospholipids ,[object Object],Contains 2 fatty acid chains that are  nonpolar Head is  polar  & contains a  –PO 4  group & glycerol copyright cmassengale
[object Object],[object Object],FLUID MOSAIC MODEL copyright cmassengale
Cell Membrane Polar heads are  hydrophilic  “water loving ” Nonpolar tails are  hydrophobic  “water fearing” Makes membrane  “Selective”  in what crosses copyright cmassengale
copyright cmassengale
Cell Membrane Hydrophobic  molecules pass  easily ; hydrophilic  DO NOT The cell membrane is made of  2 layers of  phospholipid s  called the lipid  bilayer copyright cmassengale
Solubility ,[object Object],copyright cmassengale
Semipermeable Membrane Small  molecules and  larger hydrophobic  molecules move through easily. e.g. O 2 , CO 2 , H 2 O copyright cmassengale
Ions ,  hydrophilic  molecules larger than water, and large molecules such as  proteins   do not move  through the membrane on their own.  Semipermeable Membrane copyright cmassengale
Types of Transport Across Cell Membranes copyright cmassengale
Simple Diffusion ,[object Object],[object Object],copyright cmassengale
DIFFUSION ,[object Object],copyright cmassengale
Diffusion of Liquids copyright cmassengale
Diffusion through a Membrane Cell membrane Solute moves  DOWN  concentration gradient  (HIGH to LOW) copyright cmassengale
Osmosis ,[object Object],[object Object],Diffusion across a membrane Semipermeable membrane copyright cmassengale
Diffusion of H 2 O Across A Membrane High H 2 O potential Low solute concentration Low H 2 O potential High solute concentration copyright cmassengale
Aquaporins ,[object Object],[object Object],WATER MOLECULES copyright cmassengale
Cell in Isotonic Solution CELL 10% NaCL 90% H 2 O 10% NaCL 90% H 2 O What is the direction of water movement? The cell is at _______________. equilibrium ENVIRONMENT NO NET MOVEMENT copyright cmassengale
Cell in Hypotonic Solution CELL 10% NaCL 90% H 2 O 20% NaCL 80% H 2 O What is the direction of water movement? copyright cmassengale
Cell in Hypertonic Solution CELL 15% NaCL 85% H 2 O 5% NaCL 95% H 2 O What is the direction of water movement? ENVIRONMENT copyright cmassengale
Cells in Solutions copyright cmassengale
Isotonic Solution NO NET MOVEMENT OF H 2 O (equal amounts entering & leaving) Hypotonic Solution CYTOLYSIS Hypertonic Solution PLASMOLYSIS copyright cmassengale
Cytolysis & Plasmolysis Cytolysis Plasmolysis copyright cmassengale
Osmosis in Red Blood Cells Isotonic Hypotonic Hypertonic copyright cmassengale
What Happens to Blood Cells? copyright cmassengale
hypotonic hypertonic isotonic hypertonic isotonic hypotonic copyright cmassengale
Three Forms of Transport Across the Membrane   copyright cmassengale
Passive Transport ,[object Object],[object Object],[object Object],[object Object],copyright cmassengale
Passive Transport ,[object Object],[object Object],[object Object],[object Object],copyright cmassengale
Proteins Are Critical to Membrane Function copyright cmassengale
Types of Transport Proteins ,[object Object],[object Object],copyright cmassengale
Facilitated Diffusion   Molecules will randomly move through the  pores  in  Channel Proteins . copyright cmassengale
Facilitated Diffusion ,[object Object],[object Object],copyright cmassengale
Carrier Proteins ,[object Object],copyright cmassengale
Active Transport ,[object Object],[object Object],[object Object],copyright cmassengale
Active transport ,[object Object],[object Object],copyright cmassengale
Sodium-Potassium Pump 3 Na+ pumped in for every 2 K+ pumped out; creates a membrane potential copyright cmassengale
Moving the “Big Stuff” Molecules are  moved out  of the cell by  vesicles  that  fuse  with the plasma membrane. Exocytosis -  moving things out. This is how many  hormones  are secreted and how  nerve cells  communicate with one another . copyright cmassengale
Exocytosis copyright cmassengale Exocytic vesicle immediately after fusion with plasma membrane.
Moving the “Big Stuff” Large molecules move materials into the cell by one of  three forms of endocytosis .  copyright cmassengale
Pinocytosis Most  common  form of endocytosis .   Takes in  dissolved  molecules as a vesicle .  copyright cmassengale
Pinocytosis ,[object Object],[object Object],[object Object],copyright cmassengale
Example of Pinocytosis pinocytic vesicles forming mature transport vesicle Transport across a  capillary cell  (blue). copyright cmassengale
Receptor-Mediated Endocytosis Some  integral proteins  have  receptors  on their surface to recognize & take in  hormones, cholesterol , etc. copyright cmassengale
Receptor-Mediated Endocytosis copyright cmassengale
copyright cmassengale
Endocytosis – Phagocytosis  Used to  engulf large particles  such as food,  bacteria , etc. into vesicles Called  “Cell Eating” copyright cmassengale
copyright cmassengale
Phagocytosis About to Occur copyright cmassengale
Phagocytosis  - Capture of a  Yeast  Cell (yellow) by Membrane Extensions of an  Immune System Cell  (blue) copyright cmassengale
Exocytosis   The opposite of endocytosis is exocytosis.  Large molecules  that are manufactured in the cell are  released  through the cell membrane . Inside Cell Cell environment copyright cmassengale
copyright cmassengale

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Plasma membrane

  • 1. The Plasma Membrane - Gateway to the Cell copyright cmassengale
  • 2. Photograph of a Cell Membrane copyright cmassengale
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. Structure of the Cell Membrane copyright cmassengale
  • 8. Phospholipids Cholesterol Proteins ( peripheral and integral) Carbohydrates (glucose) Membrane Components copyright cmassengale
  • 10.
  • 11.
  • 12. Cell Membrane Polar heads are hydrophilic “water loving ” Nonpolar tails are hydrophobic “water fearing” Makes membrane “Selective” in what crosses copyright cmassengale
  • 14. Cell Membrane Hydrophobic molecules pass easily ; hydrophilic DO NOT The cell membrane is made of 2 layers of phospholipid s called the lipid bilayer copyright cmassengale
  • 15.
  • 16. Semipermeable Membrane Small molecules and larger hydrophobic molecules move through easily. e.g. O 2 , CO 2 , H 2 O copyright cmassengale
  • 17. Ions , hydrophilic molecules larger than water, and large molecules such as proteins do not move through the membrane on their own. Semipermeable Membrane copyright cmassengale
  • 18. Types of Transport Across Cell Membranes copyright cmassengale
  • 19.
  • 20.
  • 21. Diffusion of Liquids copyright cmassengale
  • 22. Diffusion through a Membrane Cell membrane Solute moves DOWN concentration gradient (HIGH to LOW) copyright cmassengale
  • 23.
  • 24. Diffusion of H 2 O Across A Membrane High H 2 O potential Low solute concentration Low H 2 O potential High solute concentration copyright cmassengale
  • 25.
  • 26. Cell in Isotonic Solution CELL 10% NaCL 90% H 2 O 10% NaCL 90% H 2 O What is the direction of water movement? The cell is at _______________. equilibrium ENVIRONMENT NO NET MOVEMENT copyright cmassengale
  • 27. Cell in Hypotonic Solution CELL 10% NaCL 90% H 2 O 20% NaCL 80% H 2 O What is the direction of water movement? copyright cmassengale
  • 28. Cell in Hypertonic Solution CELL 15% NaCL 85% H 2 O 5% NaCL 95% H 2 O What is the direction of water movement? ENVIRONMENT copyright cmassengale
  • 29. Cells in Solutions copyright cmassengale
  • 30. Isotonic Solution NO NET MOVEMENT OF H 2 O (equal amounts entering & leaving) Hypotonic Solution CYTOLYSIS Hypertonic Solution PLASMOLYSIS copyright cmassengale
  • 31. Cytolysis & Plasmolysis Cytolysis Plasmolysis copyright cmassengale
  • 32. Osmosis in Red Blood Cells Isotonic Hypotonic Hypertonic copyright cmassengale
  • 33. What Happens to Blood Cells? copyright cmassengale
  • 34. hypotonic hypertonic isotonic hypertonic isotonic hypotonic copyright cmassengale
  • 35. Three Forms of Transport Across the Membrane copyright cmassengale
  • 36.
  • 37.
  • 38. Proteins Are Critical to Membrane Function copyright cmassengale
  • 39.
  • 40. Facilitated Diffusion Molecules will randomly move through the pores in Channel Proteins . copyright cmassengale
  • 41.
  • 42.
  • 43.
  • 44.
  • 45. Sodium-Potassium Pump 3 Na+ pumped in for every 2 K+ pumped out; creates a membrane potential copyright cmassengale
  • 46. Moving the “Big Stuff” Molecules are moved out of the cell by vesicles that fuse with the plasma membrane. Exocytosis - moving things out. This is how many hormones are secreted and how nerve cells communicate with one another . copyright cmassengale
  • 47. Exocytosis copyright cmassengale Exocytic vesicle immediately after fusion with plasma membrane.
  • 48. Moving the “Big Stuff” Large molecules move materials into the cell by one of three forms of endocytosis . copyright cmassengale
  • 49. Pinocytosis Most common form of endocytosis . Takes in dissolved molecules as a vesicle . copyright cmassengale
  • 50.
  • 51. Example of Pinocytosis pinocytic vesicles forming mature transport vesicle Transport across a capillary cell (blue). copyright cmassengale
  • 52. Receptor-Mediated Endocytosis Some integral proteins have receptors on their surface to recognize & take in hormones, cholesterol , etc. copyright cmassengale
  • 55. Endocytosis – Phagocytosis Used to engulf large particles such as food, bacteria , etc. into vesicles Called “Cell Eating” copyright cmassengale
  • 57. Phagocytosis About to Occur copyright cmassengale
  • 58. Phagocytosis - Capture of a Yeast Cell (yellow) by Membrane Extensions of an Immune System Cell (blue) copyright cmassengale
  • 59. Exocytosis The opposite of endocytosis is exocytosis. Large molecules that are manufactured in the cell are released through the cell membrane . Inside Cell Cell environment copyright cmassengale

Editor's Notes

  1. The Plasma Membrane 01/18/12 G. Podgorski, Biol. 1010
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