Agrobacterium tumifaciens
Horizontal gene transfer
Interkingdom gene transfer
Virulence or Vir a b c d e f g genes
Crown gall disease
Regulation of vir genes
Relaxosome
ROLE OF JASMONIC ACID IN PLANT DEVELOPMENT &DEFENCE MECHANISMBHU,Varanasi, INDIA
jasmonic acid is a plant immune hormone whicch are imortant for plant defence mechanism and development..its have important role in root growth inhibition,tuber formation,trichome formation ,senescence,flower developmentand increasing arbasculer mycorrhizal activity in root plants,recently it has been reported in various development in rice crop like spikelet development etc.....in defence its play a crucial role against insect and pathogen resistance.Recent insights into the JAs mediated plant defense cascade and better knowledge of key regulation of plant growth and development processes will help us to design future crops with increased biotic stress resistance and better adaptability under changing climate
Plants are continually exposed to harsh environmental conditions which is life- threatening for their survival. Drought is one of the major environmental constraints that highly affect plant growth and productivity worldwide. Osmotic stress due to limited availability of water during drought lead to the inhibition of photosynthesis which ultimately affect plant growth, yield and productivity. As sessile in nature, plants cannot escape from such adverse situations. Hence, to cope up with these adverse situations, plants have developed a complex array of adaptive strategies including intricate regulation of cellular, physiological, biochemical and metabolic processes to avoid or tolerate cellular dehydration. Under limited water availability, stomata plays an essential role to check water loss due to transpiration. In addition, upon perception of stress signal, a wide range of signaling cascade has been activated which ultimately initiates the expression of stress-responsive genes in a timely and coordinated manner. Abscisic acid (ABA), the universal stress hormone, highly accumulated under stress condition, also plays an important role in stress adaptation including stomatal closure and expression of stress-responsive genes. In recent times, whole genome sequencing analysis of different plants reveals that a large family of genes is expressed under different types of abiotic stresses that are involved in defense-related pathways. These genes can be grouped into three categories, genes involving recognition of osmotic stress, signal perception, and transduction and production of stress-adaptive components for physiological responses.
Abscisic acid (ABA) previously called Dormin or
Abscisin mainly because of their regulatory
effect on abscission and dormancy. This
hormone is widespread in higher plants and is
found in many different organs and tissues
(both old and young) of plants. ABA induces
abscission of the leaves of a wide variety of
plants and fruits of some plant species
Agrobacterium tumifaciens
Horizontal gene transfer
Interkingdom gene transfer
Virulence or Vir a b c d e f g genes
Crown gall disease
Regulation of vir genes
Relaxosome
ROLE OF JASMONIC ACID IN PLANT DEVELOPMENT &DEFENCE MECHANISMBHU,Varanasi, INDIA
jasmonic acid is a plant immune hormone whicch are imortant for plant defence mechanism and development..its have important role in root growth inhibition,tuber formation,trichome formation ,senescence,flower developmentand increasing arbasculer mycorrhizal activity in root plants,recently it has been reported in various development in rice crop like spikelet development etc.....in defence its play a crucial role against insect and pathogen resistance.Recent insights into the JAs mediated plant defense cascade and better knowledge of key regulation of plant growth and development processes will help us to design future crops with increased biotic stress resistance and better adaptability under changing climate
Plants are continually exposed to harsh environmental conditions which is life- threatening for their survival. Drought is one of the major environmental constraints that highly affect plant growth and productivity worldwide. Osmotic stress due to limited availability of water during drought lead to the inhibition of photosynthesis which ultimately affect plant growth, yield and productivity. As sessile in nature, plants cannot escape from such adverse situations. Hence, to cope up with these adverse situations, plants have developed a complex array of adaptive strategies including intricate regulation of cellular, physiological, biochemical and metabolic processes to avoid or tolerate cellular dehydration. Under limited water availability, stomata plays an essential role to check water loss due to transpiration. In addition, upon perception of stress signal, a wide range of signaling cascade has been activated which ultimately initiates the expression of stress-responsive genes in a timely and coordinated manner. Abscisic acid (ABA), the universal stress hormone, highly accumulated under stress condition, also plays an important role in stress adaptation including stomatal closure and expression of stress-responsive genes. In recent times, whole genome sequencing analysis of different plants reveals that a large family of genes is expressed under different types of abiotic stresses that are involved in defense-related pathways. These genes can be grouped into three categories, genes involving recognition of osmotic stress, signal perception, and transduction and production of stress-adaptive components for physiological responses.
Abscisic acid (ABA) previously called Dormin or
Abscisin mainly because of their regulatory
effect on abscission and dormancy. This
hormone is widespread in higher plants and is
found in many different organs and tissues
(both old and young) of plants. ABA induces
abscission of the leaves of a wide variety of
plants and fruits of some plant species
Metabolites, Secondary metabolites are derived from primary metabolites, Why secondary metabolites, Phenolics, Terpenoids, Alkaloids, Special nitrogen metabolites, Cuticular compounds .The major classes of these found in plants
Role of secondary metabolites in insect pest managementMohd Irshad
SECONDARY METABOLITES ARE THOSE COMPOUNDS WHICH ARE DIRECTLY INVOLVED IN PLANT DIFFENCE MECHANISM SO HERE I ADDED SOME SLIDES WITH KNOWLEDGABLE INFORMATION AND CITED SOME CLEAR CUT EXAMPLES.
PLANT SECONDARY METABOLITES IN PLANTS AND THEIR SIGNIFICANCEHemlata
Secondary metabolites attract animals for pollination and seed dispersal.
The plants used in their defence against herbivores and pathogens.
They act as agents of plant-plant competition.
They are used in making drugs, insecticides, flavours, pigments, scents, rubber, spices and other industrial materials like gums, resins for human welfare
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...
Plant secondary metabolites
1.
2. PLANT SECONADRY METABOLITES :-
Chemical compounds that do not participate
in metabolism of plants.
Secondary metabolites are organic
compounds that are not directly involved in the
normal growth, development, or reproduction
of an organism.
Unlike primary metabolites, absence of
secondary metabolites does not result in
immediate death, but rather in long term
impairment of the organism’s survivability,
fecundity or aesthetics or perhaps in no
significant change at all.
3. why secondary metabolites are produced by plants?
Secondary metabolites are produced in plants is
mainly for :-
1. Disease resistance (from fungus, bacteria,
virus and pests)
2. For pollination
3. To combat in extreme condition of stress.
Stress may be biotic or abiotic {Drought, Cold,
Temperature}
4. The classes of plant secondary metabolitesare :-
•Phenolics:- Consisting of one or more hydroxyl group bonded directly
to an aromatic hydrocarbon group.
•Alkaloids:-Synthesized from pharmacologically active compounds,
primarily composed nitrogen. Synthesized from common amino acids.
•Saponins:-works in plant defense.
•Terpenes:- Protect the plant
•Lipids:- Singling and energy storage Compounds.
•Carbohydrates :-Vital source of energy.
6. Uses of secondary metabolites:-
Secondary metabolites often play an
important role in plant defense against
herbivores and other interspecies defenses.
Humans use secondary metabolites
as medicines, flavorings, pigments,
and recreational drugs.
8. Conclusion:-
• Secondary metabolites are not involve in main biosynthetic
pathway but it is useful for plants. They are responsible for
protection of plants from stress, help in pollination and
gives disease resistivity. They are also useful for human in
many way like production of drugs, essential oil, flavoring
substances and pigments.