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Pilot of non-invasive (oral fluid) testing for HIV within a community setting Joseph Debattista* (1), Shaun Staunton (2),  Frances Birrell (3), Nicole Roudenko (4), William Rutkin (5), Craig Davis (3)  Brisbane Sexual Health & AIDS Service, Northside Health Service District  (1) ; Queensland Association for Healthy Communities  (2),  Communicable Diseases Branch, Queensland Health  (3),  Division of Immunology, Queensland Health Pathology Services, Royal Brisbane & Women’s Hospital  (4),  Toowoomba Health Service District  (5),  Queensland, Australia.
Background   ,[object Object],[object Object],[object Object],[object Object]
 
Methods   ,[object Object],[object Object]
Methods   ,[object Object],[object Object],[object Object]
Methods   ,[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object],[object Object]
Results ,[object Object],[object Object]
Results ,[object Object],[object Object],[object Object]
Age & Venue ,[object Object],[object Object],67.2 464 312 85.7 7 6 68.2 424 289 51.5 33 17 pub/club 32.8 464 152 14.3 7 1 31.8 424 135 48.5 33 16 SOPV - - 17- 84 - - 22 - 44 - - 18 - 84 - - 22 - 60 age range - - 35.6 - - 31.7 - - 36.4 - - 42.5 mean age - - 36.8 - - 28.0 - - 35.0 - - 43.5 median age 100.0 465 1.7 465 8 91.2 465 424 7.1 465 33 Number % N n % N n % N n % N n Total HIVnp HIVnn HIVpp Risk Factor
Most Recent HIV Test ,[object Object],[object Object],[object Object],7.6 410 31 0.0 7 0 6.5 370 24 21.2 33 7 last test > 4 years 7.8 410 32 0.0 7 0 8.1 370 30 6.1 33 2 last test 2- 4 years 15.1 410 62 14.3 7 1 15.9 370 59 6.1 33 2 last test 1 – 2 years 15.9 410 65 0.0 7 0 17.3 370 64 3.0 33 1 last test 7 -12 months 38.3 410 157 71.4 7 5 38.4 370 142 30.3 33 10 last test 1 - 6 months 12.4 410 51 14.3 7 1 11.1 370 41 27.3 33 9 last test < 1- 4 weeks 2.9 410 12 0.0 7 0 2.7 370 10 6.1 33 2 last test < 1week 100.0   465 1.7 465 8 91.2 465 424 7.1 465 33 Number % N n  % N n % N n % N n Total HIVnp HIVnn HIVpp Risk Factor
Number of Partners in last 6 months ,[object Object],[object Object],[object Object],0.4 453 2 0.0 7 0 0.5 414 2 0.0 32 0 Unknown number of ptnrs 3.8 453 17 0.0 7 0 2.7 414 11 18.8 32 6 number ptnrs >50 18.3 453 83 14.3 7 1 18.1 414 75 21.9 32 7 number ptnrs - 11 to 50  18.8 453 85 28.6 7 2 18.6 414 77 18.8 32 6 number ptnrs - 6 to 10 32.9 453 149 42.9 7 3 33.6 414 139 21.9 32 7 number ptnrs - 2 to 5 18.8 453 85 14.3 7 1 19.1 414 79 15.6 32 5 number ptnrs - 1 7.1 453 32 0.0 7 0 7.5 414 31 3.1 32 1 number ptnrs - none 100.0   465 1.7 465 8 91.2 465 424 7.1 465 33 Number % N n  % N n % N n % N n Total HIVnp HIVnn HIVpp Risk Factor
Unprotected Sex ,[object Object],[object Object],[object Object],[object Object],24.6 451 111 14.3 7 1 23.5 412 97 40.6 32 13 unprotected sex with casual partner 39.8 420 167 42.9 7 3 40.2 383 154 32.3 31 10 unprotected sex with regular partner 100.0   465 1.7 465 8 91.2 465 424 7.1 465 33 Number % N n  % N n % N n % N n Total HIVnp HIVnn HIVpp Risk Factor
Knowledge of Partner Status ,[object Object],[object Object],[object Object],[object Object],64.2 318 204 60.0 5 3 64.7 286 185 59.3 27 16 know ptnr status (cas) - unknown 30.5 318 97 40.0 5 2 32.2 286 92 11.1 27 3 know ptnr status (cas) -ve 5.3 318 17 0.0 5 0 3.1 286 9 29.6 27 8 know ptnr status (cas) +ve 39.2 365 143 50.0 6 3 39.2 334 131 36.0 25 9 know ptnr status (reg) -unknown 55.1 365 201 50.0 6 3 57.8 334 193 20.0 25 5 know ptnr status (reg) -ve 5.8 365 21 0.0 6 0 3.0 334 10 44.0 25 11 know ptnr status (reg) +ve 100.0   465 1.7 465 8 91.2 465 424 7.1 465 33 Number % N n  % N n % N n % N n Total HIVnp HIVnn HIVpp Risk Factor
Informed Partner of Status ,[object Object],[object Object],[object Object],[object Object],42.8 421 180 42.9 7 3 44.6 383 171 19.4 31 6 inform ptnr (cas) - none 35.2 421 148 57.1 7 4 33.2 383 127 54.8 31 17 inform ptnr (cas) - some 22.1 421 93 0.0 7 0 22.2 383 85 25.8 31 8 inform ptnr (cas) - all 35.4 427 151 42.9 7 3 36.7 390 143 16.7 30 5 inform ptnr (reg) - none 29.3 427 125 14.3 7 1 29.2 390 114 33.3 30 10 inform ptnr (reg) - some 35.4 427 151 42.9 7 3 34.1 390 133 50.0 30 15 inform ptnr (reg)-all 100.0   465 1.7 465 8 91.2 465 424 7.1 465 33 Number % N n  % N n % N n % N n Total HIVnp HIVnn HIVpp Risk Factor
Risk Factors –  HIVpp (vs HIVnn+HIVnp) 0.01 1.11 to 5.68 2.55 Had more than 11 partners in last six months 0.01 1.30 to 10.20 3.36 Informed casual partner of HIV status 0.03 1.06 to 9.92 2.91 Informed regular partner of HIV status 0.00 3.88 to 43.00 13.19 Knew HIV status of casual partner 0.00 8.28 to 79.70 25.93 Knew HIV status of regular partner 0.03 0.98 to 5.00 2.24 Unprotected sex with casual partner 0.38 0.29 to 1.62 0.71 Unprotected sex with regular partner 0.06 0.93 to 4.43 2.04 Attends SOPV p value 95% Confidence Intervals Odds Ratio Risk Factor
Results ,[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object],[object Object],[object Object]
The Orasure collection system for oral fluid has been applied in other community-based surveillance studies similar to ours. ,[object Object]
[object Object]
[object Object]
ACKNOWLEDGEMENTS ,[object Object]

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Pilot of Non Invasive Testing for HIV

  • 1. Pilot of non-invasive (oral fluid) testing for HIV within a community setting Joseph Debattista* (1), Shaun Staunton (2), Frances Birrell (3), Nicole Roudenko (4), William Rutkin (5), Craig Davis (3) Brisbane Sexual Health & AIDS Service, Northside Health Service District (1) ; Queensland Association for Healthy Communities (2), Communicable Diseases Branch, Queensland Health (3), Division of Immunology, Queensland Health Pathology Services, Royal Brisbane & Women’s Hospital (4), Toowoomba Health Service District (5), Queensland, Australia.
  • 2.
  • 3.  
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16. Risk Factors – HIVpp (vs HIVnn+HIVnp) 0.01 1.11 to 5.68 2.55 Had more than 11 partners in last six months 0.01 1.30 to 10.20 3.36 Informed casual partner of HIV status 0.03 1.06 to 9.92 2.91 Informed regular partner of HIV status 0.00 3.88 to 43.00 13.19 Knew HIV status of casual partner 0.00 8.28 to 79.70 25.93 Knew HIV status of regular partner 0.03 0.98 to 5.00 2.24 Unprotected sex with casual partner 0.38 0.29 to 1.62 0.71 Unprotected sex with regular partner 0.06 0.93 to 4.43 2.04 Attends SOPV p value 95% Confidence Intervals Odds Ratio Risk Factor
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.