This document provides instructions for properly donning and doffing personal protective equipment (PPE) when working with infectious materials. It explains that PPE should be worn to protect oneself from contamination, and outlines the proper order and techniques for putting on and taking off each piece of the equipment, including gloves, gown, face shield or goggles, mask or respirator, and shoe covers. Special attention is given to ensuring the "clean" inside areas of the PPE remain uncontaminated by only touching the "contaminated" outside surfaces when removing items and washing hands thoroughly after doffing each piece.