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STANDARD WORK
PRECAUTIONS
AND NSI
DEFINITION
• Standard Precautions are the minimum
infection prevention practices that apply to all
patient care, regardless of suspected or
confirmed infection status of the patient, in any
setting where health care is delivered.
Standard Precautions include
• Hand hygiene.
• Use of personal protective equipment (e.g.,
gloves, masks, eyewear).
• Respiratory hygiene / cough etiquette.
• Sharps safety (engineering and work practice
controls).
• Safe injection practices (i.e., aseptic technique for
parenteral medications).
• Sterile instruments and devices.
• Clean and disinfected environmental surfaces.
HAND HYGIENE
• Hand Hygiene means cleaning your hands by
using either handwashing (washing hands with
soap and water), antiseptic hand wash,
antiseptic hand rub (i.e. alcohol-based hand
sanitizer including foam or gel), or surgical
hand antisepsis
WHY CLEAN
Cleaning your hands reduces:
• The spread of potentially deadly germs to
patients
• The risk of healthcare provider colonization or
infection caused by germs acquired from the
patient
• Alcohol-based hand sanitizers are the most
effective products for reducing the number of
germs on hands
• Alcohol-based hand sanitizers are the preferred
method for cleaning your hands in most clinical
situations.
• Wash your hands with soap and water whenever
they are visibly dirty, before eating, and after
using the restroom.
Use an Alcohol-Based Hand
Sanitizer
• Immediately before touching a patient
• Before performing an aseptic task (e.g., placing an indwelling
device) or handling invasive medical devices
• Before moving from work on a soiled body site to a clean
body site on the same patient
• After touching a patient or the patient’s immediate
environment
• After contact with blood, body fluids or contaminated surfaces
When using alcohol-based hand sanitizer:
• Put product on hands and rub hands together
• Cover all surfaces until hands feel dry
• This should take around 20 seconds
Wash with Soap and Water
• When hands are visibly soiled
• After caring for a person with known or
suspected infectious diarrhea
• After known or suspected exposure to spores
(e.g. B. anthracis, C difficile outbreaks)
– When cleaning your hands with soap and water, wet
your hands first with water,
– apply the amount of product recommended by the
manufacturer to your hands
– and rub your hands together vigorously for at least 15
seconds, covering all surfaces of the hands and fingers.
– Rinse your hands with water and use disposable towels
to dry. Use towel to turn off the faucet.
– Avoid using hot water, to prevent drying of skin.
• These areas are most often missed by
healthcare providers when using alcohol-based
hand sanitizer:
• Thumbs
• Fingertips
• Between fingers
Personal Protective equipment
SHARP SAFETY
HCW/HCP EXPOSURE – NSI
An exposure that might place HCP at risk for HBV,
HCV, or HIV infection is defined as
A per-cutaneous injury (e.g., a needle-stick or
cut with a sharp object) or
Contact of mucous membrane or non-intact
skin with blood, tissue, or other body fluids that
are potentially infectious .
Infections transmitted by Sharps injury
(source: Collins & Kennedy, 1987 )
Blastomycosis Malaria
Brucellosis Mycobacteriosis
Cryptococcosis Mycoplasmosis
Diphtheria Rocky Mountain fever
Ebola fever Scrub typhus
Gonorrhoea Staphylococcus aureus
Hepatitis B Streptococcus pyogenes
Hepatitis C Syphilis
Herpes Toxoplasmosis
HIV Tuberculosis
Leptospirosis
At Risk
Exposures
Percutaneous
Injury
Hollow Needle
> Solid Sharp
Visible Blood
Deep Injury
Device In Pts
Artery or Vein
Splash
Non Intact Skin
Mucous
Membrane
Risk is more
with
Larger Volume
Severe Injury
RISKS FROM
BODY FLUIDS
Known
Infectious
Blood
Body Fluids
(Blood
Contaminated)
Semen
Vaginal
Secretions
Breast milk
Concentrated
Virus
(Used In Labs)
Potentially
Infectious
CSF
Pleural Fluid
Pericardial
Fluids
Peritoneal
Fluids
Amniotic
Fluids
Synovial
Fluids
Tissue
Samples
Non Infectious
If not Visibly
Bloody
Tears
Saliva
Urine
Feces
Sweat
Emesis
Needlestick Injuries
Most frequently during & after an injection
– Recapping, carrying needles and syringes
– Patient movement (children)
– Inappropriate disposal
Prevent Needlesticks
• Organizing the physical layout of the Injection
work area
• Minimize handling of injection equipment
» Do not carry, Do not Recap or bend
• Cleaning the Injection environment – Before and
after injections
• Safe disposal to Prevent injuries to public
Immediate Management of NSI
• IMMEDIATELY clean Exposure site –
The most important part of PEP
• Skin wounds should be washed with soap and running water
• No evidence that antiseptics are useful and caustic agents
(bleach) may do more harm than good
• Mucous membranes flushed thoroughly with water(no soap)
• Eyes irrigated with a liter of saline
Post Exposure Prophylaxis
Guidelines
• Immediate first aid
• Report incident
• Risk assessment
• Counselling
• Decision regarding use
of PEP
• Follow-up
NSI :Hepatitis B - Risk of Disease
depends on the HBeAg status
Both +ve
37-62%
Only HbsAg +ve
23-37%
Seroconversion
HBV Remains active in dried blood at Room Temperature for at
least 1 Week
Hepatitis B Vaccination in HCP
GOOD NEWS
• Those HCP’s who have been vaccinated; the vaccine offers virtually
complete protection to responders.
• Hence all HCP should be HB vaccinated
BAD NEWS
• Most HCP’s are NOT vaccinated
• 6-10% of vaccinees do NOT develop antibody
• Repeat vaccine series – 30-50% respond
• Really bad news: CDC estimates that 50-75 HCW
• die from Hep B each year
Blood Test immediately and at 6 mths
LFT and Anti HCV at 4 – 6 Mths
Interferon not recommended for prophylaxis
No Active Prophylaxis-Immunoglobulins not
effective
Determine status of Source (Anti-HCV)
HEPATITIS C –
POST EXPOSURE MANAGEMENT
POST EXPOSURE
PROPHYLAXIS FOR HIV
Rationale for HIV PEP
• HIV infects dendritic cells (DC) then regional lymph nodes
before becoming systemic
• AZT blocks infectivity of HIV infected DC
• Goal of PEP : halt viral replication before systemic infection
is established
• Peri-natal prophylaxis has been effective
FOR HIV-VIRUS Time is ESSENCE
• Animal studies show that PEP should be given
within 2-8 hours of exposure for maximal effect
• PEP may have some benefit up to 36 hrs but
seems to be ineffective if given later
Exposure code
(EC)
Exposure
EC 1 Mucous Membrane / skin integrity
compromised , Small Vol, Few drops Short
Duration
EC 2 1. Mucous Membrane / skin integrity, large
volume,long duration (several minutes or
more )
2. Percutaneous Exposure ,Less severe (solid
needle/Superficial scratch)
EC 3 Percutaneous, more severe
Hollow needle, major wound , bloody device
PEP-HIV Classification of Exposure - NACO
Source Code
(SC)
HIV status of Source
SC 1 HIV +ve , Low Titer Exposure, asymptomatic
with High CD4 Counts
SC 2 HIV +ve, High Titer Exposure ( Advanced
AIDS, Primary HIV infection/High Viral load
or Low CD4 Counts)
UnKnown Status or Source is Unknown
PEP-HIV Classification of Source -NACO
Exposure
code (EC)
Source Code
(SC)
Treatment
EC 1 SC 1 PEP may be warranted*
EC 1 SC 2 Consider Basic Regime
EC 2 SC 1 Recommend Basic Regime
( most exposures in this category)
EC 2 SC 2 Recommend Expanded Regime
EC 3 SC 1or2 Recommend Expanded Regime
2/3 Unknown Consider basic regime
PEP-HIV Treatment – NACO
ANTIRETROVIRALS FOR PEP
 Reverse transcriptase inhibitors RTI
 Nucleoside Reverse Transcriptase Inhibitors (NRTI) -
Ziduvidine, Lamuvidine
 Non nucleoside (NNRTI) - Nevirapine (not recommended)
 Protease inhibitors (PI)-Nelfinavir,Indinavir
 Single drug v/s multiple drugs for PEP - no direct
supportive evidence
 Theoretical advantage of adding an agent at a different
level
Conclusion
• Ensure reporting setup
• Update oneself on all aspects of PEP
• Ensure supply of (Start up packs) PEP medications
in your setup.
• The psychological impact of an exposure can be
enormous
• Your patience and understanding may be the best
PEP of all
Be Needle Smart
–Do NOT recap
–Do NOT bend
–Do NOT remove
–Do NOT transport
–Do NOT re-use
11

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Standard work precautions , nsi, ppe

  • 2.
  • 3.
  • 4. DEFINITION • Standard Precautions are the minimum infection prevention practices that apply to all patient care, regardless of suspected or confirmed infection status of the patient, in any setting where health care is delivered.
  • 5. Standard Precautions include • Hand hygiene. • Use of personal protective equipment (e.g., gloves, masks, eyewear). • Respiratory hygiene / cough etiquette. • Sharps safety (engineering and work practice controls). • Safe injection practices (i.e., aseptic technique for parenteral medications). • Sterile instruments and devices. • Clean and disinfected environmental surfaces.
  • 6.
  • 7. HAND HYGIENE • Hand Hygiene means cleaning your hands by using either handwashing (washing hands with soap and water), antiseptic hand wash, antiseptic hand rub (i.e. alcohol-based hand sanitizer including foam or gel), or surgical hand antisepsis
  • 8. WHY CLEAN Cleaning your hands reduces: • The spread of potentially deadly germs to patients • The risk of healthcare provider colonization or infection caused by germs acquired from the patient
  • 9. • Alcohol-based hand sanitizers are the most effective products for reducing the number of germs on hands • Alcohol-based hand sanitizers are the preferred method for cleaning your hands in most clinical situations. • Wash your hands with soap and water whenever they are visibly dirty, before eating, and after using the restroom.
  • 10. Use an Alcohol-Based Hand Sanitizer • Immediately before touching a patient • Before performing an aseptic task (e.g., placing an indwelling device) or handling invasive medical devices • Before moving from work on a soiled body site to a clean body site on the same patient • After touching a patient or the patient’s immediate environment • After contact with blood, body fluids or contaminated surfaces
  • 11. When using alcohol-based hand sanitizer: • Put product on hands and rub hands together • Cover all surfaces until hands feel dry • This should take around 20 seconds
  • 12. Wash with Soap and Water • When hands are visibly soiled • After caring for a person with known or suspected infectious diarrhea • After known or suspected exposure to spores (e.g. B. anthracis, C difficile outbreaks)
  • 13. – When cleaning your hands with soap and water, wet your hands first with water, – apply the amount of product recommended by the manufacturer to your hands – and rub your hands together vigorously for at least 15 seconds, covering all surfaces of the hands and fingers. – Rinse your hands with water and use disposable towels to dry. Use towel to turn off the faucet. – Avoid using hot water, to prevent drying of skin.
  • 14. • These areas are most often missed by healthcare providers when using alcohol-based hand sanitizer: • Thumbs • Fingertips • Between fingers
  • 15.
  • 16.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 25. HCW/HCP EXPOSURE – NSI An exposure that might place HCP at risk for HBV, HCV, or HIV infection is defined as A per-cutaneous injury (e.g., a needle-stick or cut with a sharp object) or Contact of mucous membrane or non-intact skin with blood, tissue, or other body fluids that are potentially infectious .
  • 26. Infections transmitted by Sharps injury (source: Collins & Kennedy, 1987 ) Blastomycosis Malaria Brucellosis Mycobacteriosis Cryptococcosis Mycoplasmosis Diphtheria Rocky Mountain fever Ebola fever Scrub typhus Gonorrhoea Staphylococcus aureus Hepatitis B Streptococcus pyogenes Hepatitis C Syphilis Herpes Toxoplasmosis HIV Tuberculosis Leptospirosis
  • 27. At Risk Exposures Percutaneous Injury Hollow Needle > Solid Sharp Visible Blood Deep Injury Device In Pts Artery or Vein Splash Non Intact Skin Mucous Membrane Risk is more with Larger Volume Severe Injury
  • 28. RISKS FROM BODY FLUIDS Known Infectious Blood Body Fluids (Blood Contaminated) Semen Vaginal Secretions Breast milk Concentrated Virus (Used In Labs) Potentially Infectious CSF Pleural Fluid Pericardial Fluids Peritoneal Fluids Amniotic Fluids Synovial Fluids Tissue Samples Non Infectious If not Visibly Bloody Tears Saliva Urine Feces Sweat Emesis
  • 29. Needlestick Injuries Most frequently during & after an injection – Recapping, carrying needles and syringes – Patient movement (children) – Inappropriate disposal
  • 30. Prevent Needlesticks • Organizing the physical layout of the Injection work area • Minimize handling of injection equipment » Do not carry, Do not Recap or bend • Cleaning the Injection environment – Before and after injections • Safe disposal to Prevent injuries to public
  • 31. Immediate Management of NSI • IMMEDIATELY clean Exposure site – The most important part of PEP • Skin wounds should be washed with soap and running water • No evidence that antiseptics are useful and caustic agents (bleach) may do more harm than good • Mucous membranes flushed thoroughly with water(no soap) • Eyes irrigated with a liter of saline
  • 32. Post Exposure Prophylaxis Guidelines • Immediate first aid • Report incident • Risk assessment • Counselling • Decision regarding use of PEP • Follow-up
  • 33. NSI :Hepatitis B - Risk of Disease depends on the HBeAg status Both +ve 37-62% Only HbsAg +ve 23-37% Seroconversion HBV Remains active in dried blood at Room Temperature for at least 1 Week
  • 34. Hepatitis B Vaccination in HCP GOOD NEWS • Those HCP’s who have been vaccinated; the vaccine offers virtually complete protection to responders. • Hence all HCP should be HB vaccinated BAD NEWS • Most HCP’s are NOT vaccinated • 6-10% of vaccinees do NOT develop antibody • Repeat vaccine series – 30-50% respond • Really bad news: CDC estimates that 50-75 HCW • die from Hep B each year
  • 35. Blood Test immediately and at 6 mths LFT and Anti HCV at 4 – 6 Mths Interferon not recommended for prophylaxis No Active Prophylaxis-Immunoglobulins not effective Determine status of Source (Anti-HCV) HEPATITIS C – POST EXPOSURE MANAGEMENT
  • 37. Rationale for HIV PEP • HIV infects dendritic cells (DC) then regional lymph nodes before becoming systemic • AZT blocks infectivity of HIV infected DC • Goal of PEP : halt viral replication before systemic infection is established • Peri-natal prophylaxis has been effective
  • 38. FOR HIV-VIRUS Time is ESSENCE • Animal studies show that PEP should be given within 2-8 hours of exposure for maximal effect • PEP may have some benefit up to 36 hrs but seems to be ineffective if given later
  • 39. Exposure code (EC) Exposure EC 1 Mucous Membrane / skin integrity compromised , Small Vol, Few drops Short Duration EC 2 1. Mucous Membrane / skin integrity, large volume,long duration (several minutes or more ) 2. Percutaneous Exposure ,Less severe (solid needle/Superficial scratch) EC 3 Percutaneous, more severe Hollow needle, major wound , bloody device PEP-HIV Classification of Exposure - NACO
  • 40. Source Code (SC) HIV status of Source SC 1 HIV +ve , Low Titer Exposure, asymptomatic with High CD4 Counts SC 2 HIV +ve, High Titer Exposure ( Advanced AIDS, Primary HIV infection/High Viral load or Low CD4 Counts) UnKnown Status or Source is Unknown PEP-HIV Classification of Source -NACO
  • 41. Exposure code (EC) Source Code (SC) Treatment EC 1 SC 1 PEP may be warranted* EC 1 SC 2 Consider Basic Regime EC 2 SC 1 Recommend Basic Regime ( most exposures in this category) EC 2 SC 2 Recommend Expanded Regime EC 3 SC 1or2 Recommend Expanded Regime 2/3 Unknown Consider basic regime PEP-HIV Treatment – NACO
  • 42. ANTIRETROVIRALS FOR PEP  Reverse transcriptase inhibitors RTI  Nucleoside Reverse Transcriptase Inhibitors (NRTI) - Ziduvidine, Lamuvidine  Non nucleoside (NNRTI) - Nevirapine (not recommended)  Protease inhibitors (PI)-Nelfinavir,Indinavir  Single drug v/s multiple drugs for PEP - no direct supportive evidence  Theoretical advantage of adding an agent at a different level
  • 43. Conclusion • Ensure reporting setup • Update oneself on all aspects of PEP • Ensure supply of (Start up packs) PEP medications in your setup. • The psychological impact of an exposure can be enormous • Your patience and understanding may be the best PEP of all
  • 44. Be Needle Smart –Do NOT recap –Do NOT bend –Do NOT remove –Do NOT transport –Do NOT re-use
  • 45. 11