Rheumatic fever dr.aheed
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Rheumatic fever is an autoimmune disease that can develop after a streptococcal throat infection. It causes inflammation in connective tissues, especially the heart, joints, blood vessels, and skin. The inflammation is thought to be due to an immune cross-reaction between antigens in the streptococcal bacteria and human tissues. Symptoms vary depending on which tissues are affected but can include heart valve damage, arthritis, neurological disorders like chorea. Treatment involves antibiotics, salicylates like aspirin, and steroids depending on symptoms. Long term prevention requires ongoing antibiotics to prevent future streptococcal infections from triggering recurrences of rheumatic fever.
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10 Rheumatic Fever
Rheumatic fever is an inflammatory disease that can follow a streptococcal throat infection. It involves the heart valves, joints, skin, and brain. It is caused by an abnormal immune response that causes the body to attack its own tissues. Symptoms include heart valve damage, arthritis, abnormal movements, and skin rashes. Treatment involves antibiotics, anti-inflammatory drugs, and antibiotic prophylaxis long-term to prevent recurrence. It can cause permanent heart valve damage if not properly treated.
Rheumatic fever 2018
Define rheumatic fever.
what are the main causes of rheumatic fever.
List the clinical finding of rheumatic fever.
To list and identify the most commonly used laboratory tests to detect the rheumatic fever.
How to treat rheumatic fever .
To list some of the procedures that are used for the prevention of the rheumatic fever .
Rheumatic fever
Rheumatic fever is an inflammatory disease that can occur as a result of a streptococcal infection. It is caused by an autoimmune response where antibodies created to fight the bacterial infection mistakenly attack healthy tissues in the body, especially the heart valves, joints, skin, and brain. Symptoms include heart valve damage, arthritis, abnormal skin rashes, and involuntary movements. Treatment involves antibiotics to prevent recurrent streptococcal infections, anti-inflammatory drugs, and lifelong prophylaxis to prevent future episodes of rheumatic fever.
Rheumatic fever
Rheumatic fever is an inflammatory disorder that occurs as a result of a prior streptococcal throat infection. It affects connective tissues, especially the heart. The disease most commonly affects children ages 5-15. It is characterized by symptoms like polyarthritis, carditis, chorea, and subcutaneous nodules. Long term complications include rheumatic heart disease, which can lead to problems like heart failure. Treatment involves bed rest, antibiotics to eradicate streptococci, and anti-inflammatory drugs. Recurrences can be prevented with long-term antibiotic prophylaxis.
Rheumatic fever clinical features and diagnosis
This document provides information on rheumatic fever, including its:
1) Historical background, epidemiology, pathogenesis, pathology, and clinical features such as polyarthritis, pancarditis, chorea, and subcutaneous nodules.
2) Methods of diagnosis including evidence of preceding streptococcal infection through throat culture or elevated antibody titers, as well as detecting rheumatic activity with elevated inflammatory markers.
3) The role of echocardiography in diagnosis and its increased sensitivity over clinical exam alone.
Rheumatic fever
Rheumatic fever is caused by a prior Group A streptococcal infection and causes inflammation in the heart, joints, brain, and skin. It most commonly affects children between 5-15 years old. The pathogenesis involves antibodies produced against streptococcal antigens cross-reacting with human tissues. Diagnosis is based on revised Jones criteria from 2015 including migratory arthritis, carditis, chorea, erythema marginatum, and subcutaneous nodules. Treatment involves bed rest, antibiotics to eradicate the streptococcal infection, aspirin or other anti-inflammatory drugs, and management of any heart failure. Prevention relies on promptly treating streptococcal infections and long-term antibiotics to prevent recurrences.
Rheumatic fever
Rheumatic fever is an autoimmune disease that can occur as a result of a streptococcal throat infection. It affects multiple body systems but commonly involves the heart, joints, and brain. Symptoms may include heart inflammation (carditis), painful and migratory swollen joints (arthritis), jerky involuntary movements (chorea), and others. The disease is caused by an abnormal immune response that causes antibodies produced against streptococcal bacteria to also attack human tissues. Treatment involves bed rest, antibiotics to treat the initial infection, and anti-inflammatory drugs. Recurrences of the disease can be prevented with long-term antibiotic prophylaxis but cardiac damage may persist long-term in the form of rheumatic heart disease.
ACUTE RHEUMATIC FEVER IN INDIA
RF is an autoimmune response triggered by Group A streptococcal (GAS) pharyngitis. The molecular mimicry between antigens on GAS and host tissues can lead to cross-reactive antibodies that attack the heart, joints, brain, and skin, causing inflammation. Repeated episodes can lead to rheumatic heart disease (RHD). The risk is determined by interactions between the GAS virulence factors, host genetic susceptibility, and socioeconomic environment. Countries with comprehensive prevention programs have seen declines in RF, while it remains highly prevalent in developing nations with inadequate access to healthcare.
Recommended
10 Rheumatic Fever
Rheumatic fever is an inflammatory disease that can follow a streptococcal throat infection. It involves the heart valves, joints, skin, and brain. It is caused by an abnormal immune response that causes the body to attack its own tissues. Symptoms include heart valve damage, arthritis, abnormal movements, and skin rashes. Treatment involves antibiotics, anti-inflammatory drugs, and antibiotic prophylaxis long-term to prevent recurrence. It can cause permanent heart valve damage if not properly treated.
Rheumatic fever 2018
Define rheumatic fever.
what are the main causes of rheumatic fever.
List the clinical finding of rheumatic fever.
To list and identify the most commonly used laboratory tests to detect the rheumatic fever.
How to treat rheumatic fever .
To list some of the procedures that are used for the prevention of the rheumatic fever .
Rheumatic fever
Rheumatic fever is an inflammatory disease that can occur as a result of a streptococcal infection. It is caused by an autoimmune response where antibodies created to fight the bacterial infection mistakenly attack healthy tissues in the body, especially the heart valves, joints, skin, and brain. Symptoms include heart valve damage, arthritis, abnormal skin rashes, and involuntary movements. Treatment involves antibiotics to prevent recurrent streptococcal infections, anti-inflammatory drugs, and lifelong prophylaxis to prevent future episodes of rheumatic fever.
Rheumatic fever
Rheumatic fever is an inflammatory disorder that occurs as a result of a prior streptococcal throat infection. It affects connective tissues, especially the heart. The disease most commonly affects children ages 5-15. It is characterized by symptoms like polyarthritis, carditis, chorea, and subcutaneous nodules. Long term complications include rheumatic heart disease, which can lead to problems like heart failure. Treatment involves bed rest, antibiotics to eradicate streptococci, and anti-inflammatory drugs. Recurrences can be prevented with long-term antibiotic prophylaxis.
Rheumatic fever clinical features and diagnosis
This document provides information on rheumatic fever, including its:
1) Historical background, epidemiology, pathogenesis, pathology, and clinical features such as polyarthritis, pancarditis, chorea, and subcutaneous nodules.
2) Methods of diagnosis including evidence of preceding streptococcal infection through throat culture or elevated antibody titers, as well as detecting rheumatic activity with elevated inflammatory markers.
3) The role of echocardiography in diagnosis and its increased sensitivity over clinical exam alone.
Rheumatic fever
Rheumatic fever is caused by a prior Group A streptococcal infection and causes inflammation in the heart, joints, brain, and skin. It most commonly affects children between 5-15 years old. The pathogenesis involves antibodies produced against streptococcal antigens cross-reacting with human tissues. Diagnosis is based on revised Jones criteria from 2015 including migratory arthritis, carditis, chorea, erythema marginatum, and subcutaneous nodules. Treatment involves bed rest, antibiotics to eradicate the streptococcal infection, aspirin or other anti-inflammatory drugs, and management of any heart failure. Prevention relies on promptly treating streptococcal infections and long-term antibiotics to prevent recurrences.
Rheumatic fever
Rheumatic fever is an autoimmune disease that can occur as a result of a streptococcal throat infection. It affects multiple body systems but commonly involves the heart, joints, and brain. Symptoms may include heart inflammation (carditis), painful and migratory swollen joints (arthritis), jerky involuntary movements (chorea), and others. The disease is caused by an abnormal immune response that causes antibodies produced against streptococcal bacteria to also attack human tissues. Treatment involves bed rest, antibiotics to treat the initial infection, and anti-inflammatory drugs. Recurrences of the disease can be prevented with long-term antibiotic prophylaxis but cardiac damage may persist long-term in the form of rheumatic heart disease.
ACUTE RHEUMATIC FEVER IN INDIA
RF is an autoimmune response triggered by Group A streptococcal (GAS) pharyngitis. The molecular mimicry between antigens on GAS and host tissues can lead to cross-reactive antibodies that attack the heart, joints, brain, and skin, causing inflammation. Repeated episodes can lead to rheumatic heart disease (RHD). The risk is determined by interactions between the GAS virulence factors, host genetic susceptibility, and socioeconomic environment. Countries with comprehensive prevention programs have seen declines in RF, while it remains highly prevalent in developing nations with inadequate access to healthcare.
Acute rheumatic fever
Acute rheumatic fever is a multisystem disease caused by an autoimmune reaction to a Group A streptococcal infection. It commonly affects children between 5-14 years old in developing countries. Symptoms include migratory polyarthritis, carditis, chorea, and skin manifestations. Diagnosis is based on clinical features and evidence of a preceding streptococcal infection. Treatment involves antibiotics to prevent recurrence and symptom relief. Ongoing antibiotic prophylaxis is also needed long-term to prevent recurrence, especially in those who develop cardiac involvement.
Rheumatic fever
Rheumatic fever is an inflammatory disease that occurs as a delayed reaction to a Group A streptococcal throat infection. It most commonly affects children between 5-18 years old. The main manifestations include arthritis, carditis, chorea, and less commonly subcutaneous nodules and erythema marginatum. It is diagnosed using the revised Jones criteria which requires evidence of a preceding streptococcal infection and either two major manifestations or one major and two minor manifestations. Treatment involves primary prevention through antibiotic treatment of streptococcal infections, anti-inflammatory treatment such as aspirin for arthritis and steroids for carditis, supportive management of complications, and long-term secondary prevention through antibiotic prophylaxis.
Rheumatic Fever
Rheumatic fever is an autoimmune condition that occurs as a complication of group A streptococcal infection, usually streptococcal pharyngitis. It causes inflammation of the heart, joints, skin, and brain. Diagnosis is based on the modified Jones criteria which requires either two major manifestations like carditis, polyarthritis, chorea, subcutaneous nodules, or erythema marginatum or one major manifestation plus two minor manifestations along with evidence of a prior streptococcal infection. Treatment involves antibiotics and medications for symptom management.
Rheumatic fever in pediatrics
Rheumatic fever is a non-suppurative sequelae to group A streptococcal pharyngitis that causes inflammation in connective tissues like heart, blood vessels, joints, and brain. It is most common in children ages 5-15 from developing countries. The disease is caused by an abnormal immune response 1-3 weeks after streptococcal infection. Symptoms include migratory arthritis, heart valve damage, chorea, and subcutaneous nodules. Diagnosis is based on modified Jones criteria. Treatment involves antibiotics for streptococcal infection, aspirin or steroids for inflammation, and lifelong antibiotic prophylaxis to prevent recurrence, especially if carditis is present. Prognosis depends on age and whether
Rheumatic heart disease
Rheumatic heart disease is caused by an autoimmune reaction to strep throat infection. It involves inflammation of the heart valves and can lead to valve damage over time. The mitral and aortic valves are most commonly affected, resulting in stenosis or insufficiency. Symptoms may include fever, joint pain, or heart murmurs. Treatment involves antibiotics to prevent recurrence, along with medications, activity restriction, and possibly valve surgery for severe cases. Nursing care focuses on reducing fever, monitoring the heart for changes, limiting activity, and educating patients and their families.
Rheumatic fever
1) Acute rheumatic fever is a non-suppurative sequelae that occurs 1-3 weeks after a group A streptococcal infection, causing inflammatory damage to the heart, joints, skin and brain.
2) It most commonly affects children ages 5-15 and is more prevalent in developing countries.
3) The pathogenesis involves an autoimmune response triggered by antibodies produced against the streptococcal infection. This causes inflammatory lesions and damage to tissues.
4) Diagnosis is based on modified Jones criteria which requires evidence of prior streptococcal infection plus either two major clinical manifestations or one major and two minor manifestations. Treatment involves antibiotics to treat the initial infection along with anti-inflammatory drugs
Acute Rheumatic Fever
Acute rheumatic fever is an autoimmune disease that may occur following group A streptococcal throat infection.
Rheumatic fever
Rheumatic fever is an inflammatory disease that occurs as a result of a prior streptococcal infection. It commonly affects children between 5-15 years old. The major systems involved are the heart, joints, skin, and brain. In the heart, it can cause inflammation of the tissues and valves, leading to scarring and deformities over time. On pathology, it is characterized by lesions called Aschoff bodies in the heart muscle. Long term, it can progress to chronic rheumatic heart disease with permanent valve damage and heart failure. Prompt treatment of streptococcal infections can help prevent recurrent cases of rheumatic fever.
Ms mr rhd
This document discusses rheumatic heart disease, which is permanent heart valve damage caused by one or more attacks of acute rheumatic fever following a streptococcal throat infection. It covers the epidemiology, pathogenesis, clinical manifestations, diagnosis, and management of rheumatic heart disease. The pathogenesis involves an autoimmune response triggered by the throat infection that causes inflammation of the heart valves. Diagnosis is based on modified Jones criteria and physical exam may reveal murmurs from valve damage. Rheumatic heart disease remains an important cause of morbidity in developing countries.
Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in ...
Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in the Era of Doppler Echocardiography A Scientific Statement From the American Heart Association
Rheumatic Fever by Adnan Bhutto
Rheumatic fever is caused by a delayed immune response to group A beta-hemolytic streptococcal infection. It primarily affects the heart, joints, subcutaneous tissue, and brain. It is more common in developing countries and affects children between 5-15 years old. Symptoms include arthritis, carditis, Sydenham's chorea, subcutaneous nodules, and erythema marginatum. Diagnosis is based on modified Jones criteria and treatment involves antibiotics, anti-inflammatories, and long-term prevention of recurrent infections.
Rheumatic fever & acute rheumatic heart disease Rheumatic fever & acute rhe...
Rheumatic fever is caused by an autoimmune response following a Group A streptococcal throat infection. It can affect the heart, joints, brain and skin. Heart involvement occurs in 50% of cases and can lead to permanent valve damage over years. Diagnosis is based on Jones criteria of evidence of prior streptococcal infection and major/minor clinical manifestations. Treatment involves bed rest, antibiotics, anti-inflammatories and secondary prophylaxis with antibiotics to prevent recurrence. Recurrence risks are higher if the initial attack involved heart inflammation. Long term follow up is needed due to risk of developing chronic rheumatic heart disease.
ACUTE RHEUMATIC FEVER IN THE PAST AND PRESENT
Rheumatic fever is an inflammatory disease that can affect the heart, joints, brain and skin. It is caused by a prior untreated streptococcal throat infection. The disease was once very common but is now rare in developed countries. Symptoms include migratory arthritis, heart inflammation (carditis), abnormal movements (Sydenham's chorea), and subcutaneous nodules. Carditis is the most serious manifestation as it can lead to long-term heart valve damage and chronic rheumatic heart disease. Echocardiography plays an important role in the diagnosis of carditis. Prompt treatment of streptococcal infections and ongoing prevention medication can now largely prevent recurrent rheumatic fever in susceptible individuals.
Rheumatic fever
Acute rheumatic fever is an immune-mediated disease that can occur weeks after a Group A Streptococcal (GAS) infection. It most commonly affects children between 5-15 years of age in areas where GAS infections are endemic. The pathogenesis involves molecular mimicry between antigens in GAS and human tissues, leading to inflammation in multiple organs. Clinical manifestations include carditis, arthritis, skin lesions, and Sydenham's chorea. Diagnosis is based on the revised Jones criteria and evidence of a preceding GAS infection. Treatment involves antibiotics to eradicate any residual infection and aspirin or corticosteroids for symptom relief. Secondary prophylaxis with benzathine penicillin injections is important to
ACUTE RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
This document discusses acute rheumatic fever and rheumatic heart disease. It begins by outlining the objectives of understanding the epidemiology, pathogenesis, clinical features, laboratory studies, and management. It then describes how acute rheumatic fever is an autoimmune response to Group A streptococcal infection that causes inflammation in multiple organs. The Jones criteria are used for diagnosis and require certain major or minor clinical features. Management involves treating underlying streptococcal infections and suppressing inflammation. Primary prevention focuses on proper treatment of streptococcal pharyngitis to prevent recurrent rheumatic fever.
Acute rheumatic fever-definition,pathophysiology,clinical presentation and ma...
A detailed approach to ACUTE RHEUMATIC FEVER,based on Harrison Principles of internal medicine and Braunwald Textbook of Cardiology.Useful for post graduate seminars.
Rheumatic fever - all you need to know
Teaching presentation on Rheumatic fever, including etiology, clinical features, diagnosis and treatment. Evidence based approach in management.
Rheumatic fever
Rheumatic fever- a multifactorial disease that follows GAS pharyngitis in a susceptible individual who lives under deprived social conditions, characterized by acute inflammation of the heart, joints, skin, subcutaneous tissue & CNS, that gives rise to typical clinical feature including Arthritis, Carditis, Chorea, Subcutaneous nodules & Erythema marginatum.
Latent period of 2-3 weeks following GAS pharangitis.
Destructive effects on heart valves leads to RHD with serious hemodynamic disturbances causing HF, stroke & infective endocarditis.
Acute rheumatic fever
This document provides information on acute rheumatic fever (ARF), including its definition, incidence, pathophysiology, diagnosis, management, and secondary prevention. ARF is an autoimmune response to Group A streptococcal infection that causes inflammation of the heart, joints, brain and skin. It predominantly affects school-aged children and those in low socioeconomic conditions. Accurate diagnosis is important to avoid over- or under-treatment. Management involves treating streptococcal infections, suppressing inflammation, and long-term antibiotic prophylaxis to prevent recurrence.
Rheumatic heart disease: Acute Rheumatic Fever
This document summarizes rheumatic heart disease and acute rheumatic fever. It begins by introducing ARF as an autoimmune response to strep throat that causes inflammation in multiple organs including the heart. This can lead to rheumatic heart disease over time. It then covers the pathophysiology, diagnostic criteria, manifestations involving the heart, joints, skin and neurological system. Secondary prevention through antibiotic prophylaxis is discussed. Chronic rheumatic heart disease and its effects on the heart valves are also summarized.
Acute Rheumatic Fever
This document discusses acute rheumatic fever, an inflammatory disorder caused by an untreated Group A streptococcal infection. It is characterized by an inflammatory lesion of the connective tissues, especially the heart, joints, blood vessels, and skin. The main manifestations include carditis, arthritis, chorea, erythema marginatum, and subcutaneous nodules. The pathogenesis involves an autoimmune response triggered by the streptococcal infection that results in damage to connective tissues. Diagnosis is based on the Jones criteria of major and minor manifestations along with evidence of a prior streptococcal infection. Complications can include permanent cardiac damage if carditis is not properly treated.
L1.. rheumatic fever
Rheumatic fever is a sequel to group A streptococcal infection, usually of the throat. It causes chronic damage to the heart valves. The Jones criteria are used to diagnose it based on major manifestations like carditis or migratory polyarthritis, and minor criteria like fever or arthritis. Treatment involves antibiotics for the streptococcal infection, aspirin or steroids for inflammation, and lifelong antibiotic prophylaxis to prevent recurrence and further heart damage. Preventing initial streptococcal infections is key to reducing rheumatic fever incidence.
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Acute rheumatic fever
Acute rheumatic fever is a multisystem disease caused by an autoimmune reaction to a Group A streptococcal infection. It commonly affects children between 5-14 years old in developing countries. Symptoms include migratory polyarthritis, carditis, chorea, and skin manifestations. Diagnosis is based on clinical features and evidence of a preceding streptococcal infection. Treatment involves antibiotics to prevent recurrence and symptom relief. Ongoing antibiotic prophylaxis is also needed long-term to prevent recurrence, especially in those who develop cardiac involvement.
Rheumatic fever
Rheumatic fever is an inflammatory disease that occurs as a delayed reaction to a Group A streptococcal throat infection. It most commonly affects children between 5-18 years old. The main manifestations include arthritis, carditis, chorea, and less commonly subcutaneous nodules and erythema marginatum. It is diagnosed using the revised Jones criteria which requires evidence of a preceding streptococcal infection and either two major manifestations or one major and two minor manifestations. Treatment involves primary prevention through antibiotic treatment of streptococcal infections, anti-inflammatory treatment such as aspirin for arthritis and steroids for carditis, supportive management of complications, and long-term secondary prevention through antibiotic prophylaxis.
Rheumatic Fever
Rheumatic fever is an autoimmune condition that occurs as a complication of group A streptococcal infection, usually streptococcal pharyngitis. It causes inflammation of the heart, joints, skin, and brain. Diagnosis is based on the modified Jones criteria which requires either two major manifestations like carditis, polyarthritis, chorea, subcutaneous nodules, or erythema marginatum or one major manifestation plus two minor manifestations along with evidence of a prior streptococcal infection. Treatment involves antibiotics and medications for symptom management.
Rheumatic fever in pediatrics
Rheumatic fever is a non-suppurative sequelae to group A streptococcal pharyngitis that causes inflammation in connective tissues like heart, blood vessels, joints, and brain. It is most common in children ages 5-15 from developing countries. The disease is caused by an abnormal immune response 1-3 weeks after streptococcal infection. Symptoms include migratory arthritis, heart valve damage, chorea, and subcutaneous nodules. Diagnosis is based on modified Jones criteria. Treatment involves antibiotics for streptococcal infection, aspirin or steroids for inflammation, and lifelong antibiotic prophylaxis to prevent recurrence, especially if carditis is present. Prognosis depends on age and whether
Rheumatic heart disease
Rheumatic heart disease is caused by an autoimmune reaction to strep throat infection. It involves inflammation of the heart valves and can lead to valve damage over time. The mitral and aortic valves are most commonly affected, resulting in stenosis or insufficiency. Symptoms may include fever, joint pain, or heart murmurs. Treatment involves antibiotics to prevent recurrence, along with medications, activity restriction, and possibly valve surgery for severe cases. Nursing care focuses on reducing fever, monitoring the heart for changes, limiting activity, and educating patients and their families.
Rheumatic fever
1) Acute rheumatic fever is a non-suppurative sequelae that occurs 1-3 weeks after a group A streptococcal infection, causing inflammatory damage to the heart, joints, skin and brain.
2) It most commonly affects children ages 5-15 and is more prevalent in developing countries.
3) The pathogenesis involves an autoimmune response triggered by antibodies produced against the streptococcal infection. This causes inflammatory lesions and damage to tissues.
4) Diagnosis is based on modified Jones criteria which requires evidence of prior streptococcal infection plus either two major clinical manifestations or one major and two minor manifestations. Treatment involves antibiotics to treat the initial infection along with anti-inflammatory drugs
Acute Rheumatic Fever
Acute rheumatic fever is an autoimmune disease that may occur following group A streptococcal throat infection.
Rheumatic fever
Rheumatic fever is an inflammatory disease that occurs as a result of a prior streptococcal infection. It commonly affects children between 5-15 years old. The major systems involved are the heart, joints, skin, and brain. In the heart, it can cause inflammation of the tissues and valves, leading to scarring and deformities over time. On pathology, it is characterized by lesions called Aschoff bodies in the heart muscle. Long term, it can progress to chronic rheumatic heart disease with permanent valve damage and heart failure. Prompt treatment of streptococcal infections can help prevent recurrent cases of rheumatic fever.
Ms mr rhd
This document discusses rheumatic heart disease, which is permanent heart valve damage caused by one or more attacks of acute rheumatic fever following a streptococcal throat infection. It covers the epidemiology, pathogenesis, clinical manifestations, diagnosis, and management of rheumatic heart disease. The pathogenesis involves an autoimmune response triggered by the throat infection that causes inflammation of the heart valves. Diagnosis is based on modified Jones criteria and physical exam may reveal murmurs from valve damage. Rheumatic heart disease remains an important cause of morbidity in developing countries.
Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in ...
Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in the Era of Doppler Echocardiography A Scientific Statement From the American Heart Association
Rheumatic Fever by Adnan Bhutto
Rheumatic fever is caused by a delayed immune response to group A beta-hemolytic streptococcal infection. It primarily affects the heart, joints, subcutaneous tissue, and brain. It is more common in developing countries and affects children between 5-15 years old. Symptoms include arthritis, carditis, Sydenham's chorea, subcutaneous nodules, and erythema marginatum. Diagnosis is based on modified Jones criteria and treatment involves antibiotics, anti-inflammatories, and long-term prevention of recurrent infections.
Rheumatic fever & acute rheumatic heart disease Rheumatic fever & acute rhe...
Rheumatic fever is caused by an autoimmune response following a Group A streptococcal throat infection. It can affect the heart, joints, brain and skin. Heart involvement occurs in 50% of cases and can lead to permanent valve damage over years. Diagnosis is based on Jones criteria of evidence of prior streptococcal infection and major/minor clinical manifestations. Treatment involves bed rest, antibiotics, anti-inflammatories and secondary prophylaxis with antibiotics to prevent recurrence. Recurrence risks are higher if the initial attack involved heart inflammation. Long term follow up is needed due to risk of developing chronic rheumatic heart disease.
ACUTE RHEUMATIC FEVER IN THE PAST AND PRESENT
Rheumatic fever is an inflammatory disease that can affect the heart, joints, brain and skin. It is caused by a prior untreated streptococcal throat infection. The disease was once very common but is now rare in developed countries. Symptoms include migratory arthritis, heart inflammation (carditis), abnormal movements (Sydenham's chorea), and subcutaneous nodules. Carditis is the most serious manifestation as it can lead to long-term heart valve damage and chronic rheumatic heart disease. Echocardiography plays an important role in the diagnosis of carditis. Prompt treatment of streptococcal infections and ongoing prevention medication can now largely prevent recurrent rheumatic fever in susceptible individuals.
Rheumatic fever
Acute rheumatic fever is an immune-mediated disease that can occur weeks after a Group A Streptococcal (GAS) infection. It most commonly affects children between 5-15 years of age in areas where GAS infections are endemic. The pathogenesis involves molecular mimicry between antigens in GAS and human tissues, leading to inflammation in multiple organs. Clinical manifestations include carditis, arthritis, skin lesions, and Sydenham's chorea. Diagnosis is based on the revised Jones criteria and evidence of a preceding GAS infection. Treatment involves antibiotics to eradicate any residual infection and aspirin or corticosteroids for symptom relief. Secondary prophylaxis with benzathine penicillin injections is important to
ACUTE RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
This document discusses acute rheumatic fever and rheumatic heart disease. It begins by outlining the objectives of understanding the epidemiology, pathogenesis, clinical features, laboratory studies, and management. It then describes how acute rheumatic fever is an autoimmune response to Group A streptococcal infection that causes inflammation in multiple organs. The Jones criteria are used for diagnosis and require certain major or minor clinical features. Management involves treating underlying streptococcal infections and suppressing inflammation. Primary prevention focuses on proper treatment of streptococcal pharyngitis to prevent recurrent rheumatic fever.
Acute rheumatic fever-definition,pathophysiology,clinical presentation and ma...
A detailed approach to ACUTE RHEUMATIC FEVER,based on Harrison Principles of internal medicine and Braunwald Textbook of Cardiology.Useful for post graduate seminars.
Rheumatic fever - all you need to know
Teaching presentation on Rheumatic fever, including etiology, clinical features, diagnosis and treatment. Evidence based approach in management.
Rheumatic fever
Rheumatic fever- a multifactorial disease that follows GAS pharyngitis in a susceptible individual who lives under deprived social conditions, characterized by acute inflammation of the heart, joints, skin, subcutaneous tissue & CNS, that gives rise to typical clinical feature including Arthritis, Carditis, Chorea, Subcutaneous nodules & Erythema marginatum.
Latent period of 2-3 weeks following GAS pharangitis.
Destructive effects on heart valves leads to RHD with serious hemodynamic disturbances causing HF, stroke & infective endocarditis.
Acute rheumatic fever
This document provides information on acute rheumatic fever (ARF), including its definition, incidence, pathophysiology, diagnosis, management, and secondary prevention. ARF is an autoimmune response to Group A streptococcal infection that causes inflammation of the heart, joints, brain and skin. It predominantly affects school-aged children and those in low socioeconomic conditions. Accurate diagnosis is important to avoid over- or under-treatment. Management involves treating streptococcal infections, suppressing inflammation, and long-term antibiotic prophylaxis to prevent recurrence.
Rheumatic heart disease: Acute Rheumatic Fever
This document summarizes rheumatic heart disease and acute rheumatic fever. It begins by introducing ARF as an autoimmune response to strep throat that causes inflammation in multiple organs including the heart. This can lead to rheumatic heart disease over time. It then covers the pathophysiology, diagnostic criteria, manifestations involving the heart, joints, skin and neurological system. Secondary prevention through antibiotic prophylaxis is discussed. Chronic rheumatic heart disease and its effects on the heart valves are also summarized.
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Similar to Rheumatic fever dr.aheed
Acute Rheumatic Fever
This document discusses acute rheumatic fever, an inflammatory disorder caused by an untreated Group A streptococcal infection. It is characterized by an inflammatory lesion of the connective tissues, especially the heart, joints, blood vessels, and skin. The main manifestations include carditis, arthritis, chorea, erythema marginatum, and subcutaneous nodules. The pathogenesis involves an autoimmune response triggered by the streptococcal infection that results in damage to connective tissues. Diagnosis is based on the Jones criteria of major and minor manifestations along with evidence of a prior streptococcal infection. Complications can include permanent cardiac damage if carditis is not properly treated.
L1.. rheumatic fever
Rheumatic fever is a sequel to group A streptococcal infection, usually of the throat. It causes chronic damage to the heart valves. The Jones criteria are used to diagnose it based on major manifestations like carditis or migratory polyarthritis, and minor criteria like fever or arthritis. Treatment involves antibiotics for the streptococcal infection, aspirin or steroids for inflammation, and lifelong antibiotic prophylaxis to prevent recurrence and further heart damage. Preventing initial streptococcal infections is key to reducing rheumatic fever incidence.
Rf
Rheumatic fever is caused by a prior streptococcal infection and results in inflammation of the heart, joints, nervous system and skin. It occurs in about 2% of individuals after strep throat. Genetics and socioeconomic factors influence susceptibility. Diagnosis is based on evidence of a prior strep infection and meeting criteria involving heart, joints, rash and chorea symptoms. Treatment focuses on relieving symptoms, preventing recurrence with long-term antibiotics, and managing any heart valve damage.
Rheumatic fever
Rheumatic fever is an inflammatory disease that can occur 2-3 weeks after a streptococcal infection like strep throat. It is caused by an autoimmune reaction where antibodies created to fight streptococcus mistakenly attack heart, joints, brain and skin tissues. Treatment involves antibiotics to eliminate streptococcus, medications to reduce inflammation and symptoms, and preventing recurrent episodes through ongoing antibiotic prophylaxis. Complications can include long-term heart valve damage leading to mitral stenosis, regurgitation or heart failure if not properly treated.
ACUTE RHEUMATIC FEVER PPT.pptx
Acute rheumatic fever is an auto immune disease, triggered by infection with specific strains of Streptococcus pyogenes, i.e. group A Streptococcus (GAS)
It affects the various organs like heart, joints, blood vessels , brain and connective tissues
RheumaticFever.ppt
1. Acute rheumatic fever is a systemic disease that primarily affects the heart, joints, skin, and brain in children following a streptococcal throat infection.
2. It is caused by an autoimmune response 2-3 weeks after streptococcal pharyngitis.
3. Diagnosis is based on the modified Jones criteria and treatment involves antibiotics for streptococcal infections, anti-inflammatory drugs like aspirin and steroids, and long-term antibiotic prophylaxis to prevent recurrent attacks.
RheumaticFever (1).ppt
1. Acute rheumatic fever is a non-suppurative sequelae that occurs 1-3 weeks after a Group A streptococcal infection of the throat, and results in immune-mediated damage to connective tissues, especially the heart valves.
2. It most commonly affects children between 5-15 years of age, and is diagnosed based on the modified Jones criteria which looks for major manifestations like carditis, polyarthritis, chorea or minor manifestations along with evidence of a prior streptococcal infection.
3. Treatment involves antibiotics to treat the initial strep infection, anti-inflammatory drugs like aspirin and steroids to reduce inflammation, and long-term antibiotic prophylaxis to prevent
K rheumatic fever-yds
1. Acute rheumatic fever is a systemic disease that follows group A streptococcal infection and causes inflammation of connective tissues, especially the heart.
2. It most commonly affects children ages 5-15 and is more prevalent in developing countries. The symptoms include migratory arthritis, carditis, chorea, and subcutaneous nodules.
3. Diagnosis is based on the modified Jones criteria of either two major symptoms or one major and two minor symptoms along with evidence of a prior streptococcal infection. Treatment involves antibiotics to treat strep, anti-inflammatories, and long-term antibiotic prophylaxis to prevent recurrence.
Acute rheumatic fever
Rheumatic fever is an inflammatory disease that affects the heart, joints, skin and nervous system following a streptococcal throat infection. It can cause permanent heart valve damage. Symptoms include fever, arthritis and heart inflammation. Treatment focuses on relieving symptoms, eliminating streptococcal infection, and preventing cardiac damage through bed rest and medications like salicylates or corticosteroids. Long-term antibiotic prophylaxis is needed to prevent recurrences, especially for those who develop heart valve problems.
Acute rheumatic fever
This document provides information on acute rheumatic fever. It defines rheumatic fever as an autoimmune condition that can occur weeks after a streptococcal throat infection. It affects children aged 5-15 and can cause arthritis, carditis, chorea, erythema marginatum, and subcutaneous nodules. Carditis is the most serious manifestation, often resulting in long term rheumatic heart disease. The document reviews the epidemiology, etiology, pathogenesis, clinical manifestations, diagnosis according to the revised Jones criteria, and long term sequelae including rheumatic heart disease.
ARF DEV (1).pptx
- Acute rheumatic fever is an autoimmune disease that develops after a streptococcal infection. It can cause inflammation in joints, heart valves, brain, and skin.
- The document discusses the etiology, pathogenesis, clinical features, and management of acute rheumatic fever. It is caused by an immune reaction to a streptococcal infection that results in cross-reactivity with human tissues. Common symptoms include polyarthritis, carditis, chorea, and erythema marginatum.
- Diagnosis involves confirming a preceding streptococcal infection through elevated antibody titers as well as evidence of systemic inflammation from tests like ESR and CRP. Echocardiography and ECG can
Acute rheumatic fever & rheumatic heart disease
Acute rheumatic fever & Rheumatic heart disease presentation, diagnosis, management, prophylaxis, complications and follow up.
Rheumatic heart disease
Rheumatic fever is an autoimmune disease that can develop as a result of a streptococcal throat infection. It causes inflammation of the heart, joints, brain, and skin. The disease is most common in children ages 5-15 in developing countries. It is diagnosed using the Modified Jones Criteria which looks for major criteria like heart inflammation, arthritis, subcutaneous nodules, and minor criteria like fever and joint pain along with evidence of a prior streptococcal infection. Treatment involves antibiotics to treat the infection as well as medications for symptoms while long term prevention relies on regular antibiotics.
Rheumatic fever
Rheumatic fever is an autoimmune condition that can occur 2-4 weeks after a streptococcal throat infection. It is characterized by inflammation of the heart, blood vessels, joints, brain and skin. It most commonly affects children ages 5-15 and is caused by certain strains of streptococcus bacteria. Left untreated, it can cause long term heart damage known as rheumatic heart disease. Treatment involves antibiotics to treat infections as well as medications to reduce inflammation and manage symptoms. Long term preventative antibiotics may also be needed to prevent recurrent infections and further heart damage.
RHD and IE.pptx
Rheumatic fever is an inflammatory disease that can occur after a streptococcal throat infection and cause permanent heart damage known as rheumatic heart disease. Rheumatic heart disease involves valve damage, usually to the mitral valve, which initially causes regurgitation and later stenosis. Infective endocarditis is a bacterial infection of the heart valves or inner lining of the heart. It commonly involves the formation of vegetations on the valves. Diagnosis involves blood cultures and echocardiography. Treatment consists of prolonged intravenous antibiotics targeting the specific bacterium along with surgery in some severe cases. Prophylactic antibiotics are recommended for at-risk patients undergoing certain medical procedures to prevent transient bacteremias from causing infective
Bacterial endocarditis
This document provides an overview of infective endocarditis, including its definition, epidemiology, anatomy, pathogenesis, classification, etiology, risk factors, clinical manifestations, diagnosis, management, and complications. Infective endocarditis is a bacterial or fungal infection of the heart valves or endocardium. It most commonly affects the mitral valve and is usually caused by streptococci, staphylococci, or enterococci. It can be acute or subacute and is diagnosed using the modified Duke criteria.
Rheumatic heart disease agp
Rheumatic fever and rheumatic heart disease are conditions that can occur after a streptococcal throat infection. Rheumatic fever is an inflammatory disease that affects the heart, joints, skin, and blood vessels. It is characterized by lesions called Aschoff bodies and rheumatic granulomas. Long term, it can lead to rheumatic heart disease where the heart valves are damaged. The disease process involves an immune response to streptococcal antigens that causes inflammation and tissue damage. Symptoms vary by the organs involved but can include fever, arthritis, heart valve abnormalities, and skin rashes.
2010 3-17-hfrs
Hemorrhagic Fever with Renal Syndrome (HFRS) is caused by Hantaan viruses. It is characterized by fever, hemorrhage, proteinuria, shock, and acute renal failure. There are typically five phases: febrile, hypotensive, oliguric, diuretic, and convalescent. Laboratory findings include leukocytosis, thrombocytopenia, increased BUN and creatinine, and detection of Hantaan virus antigen or antibody. The disease is diagnosed based on clinical features, epidemiological data, and laboratory examinations.
5 Hemorrhagic Fever With Renal Syndrome
Hemorrhagic Fever with Renal Syndrome (HFRS) is caused by Hantaan viruses. It is characterized by fever, hemorrhage, acute kidney injury, and typically progresses through five phases - febrile, hypotensive, oliguric, diuretic, and convalescent. The febrile phase involves high fever, flushed skin, hemorrhaging, and protein in the urine. Later phases can involve shock, reduced urine output, electrolyte imbalances, and eventual recovery of kidney function.
Rheumatic fever in children
This document provides information about acute rheumatic fever, including its etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis, treatment, and prognosis. It is caused by a delayed immune response to a Group A streptococcal infection. It most commonly affects children ages 5-15 and can cause inflammation of the heart, joints, subcutaneous tissue, and brain. Diagnosis is based on the modified Jones criteria and treatment involves antibiotics, anti-inflammatories, and long-term antibiotic prophylaxis to prevent recurrences. While arthritis and chorea typically resolve, carditis can cause permanent heart valve damage.
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Acute rheumatic fever & rheumatic heart disease
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Rheumatic fever dr.aheed
- 1. Type to enter a caption. Rheumatic Fever DR.AHEED KHAN DNB RESIDENT DEPARTMENT OF PEDIATRICS MAX HOSPITAL PPG {aheedk@gmail.com}
- 2. Type to enter a caption. Multisystem Immunological disorder initiated by group A beta hemolytic Streptococus It is characterized by an exudative and proliferative inflammatory lesion of the connective tissue, especially that of the heart joints, blood vessels and subcutaneous tissue.
- 3. ETIOLOGY • An untreated Group- A beta hemolytic streptococcal infection is the commonest antecedent event that precipitates an attack of Acute Rheumatic Fever. It is a delayed non-suppurative sequelae to URTI with GABH streptococci.
- 4. licks the joints; bites the heart• Acute ARF is an immuno-inflammatory condition that presents as • carditis • Arthritis • chorea • subcutaneous nodules • erythema marginatum
- 5. The portal of entry is usually the fauces. Sore throat Frank scarlet fever Otitis media Other streptococcal infection precede the onset of the disease Type to enter a caption.
- 6. • Group A streptococcus(e.g., M types-1, 3, 5, 6, 18, 24) are more frequently isolated from patients with acute rheumatic fever. • cross reactive antigens: • cardiac myofibrillar sm Ag-cell wall/ cell membrane Ag • heart valve fibroblast Ag- cell membrane Ag • subthalamic and caudate nuclei Ag-Gp- A cell membrane Strep Ag • heart valve and connective tissue- Gp-A carbohydrate Ag Type to enter a caption. cross reactivity
- 7. epidemiology • The incidence of both initial attacks and recurrences of acute rheu • India- 0.5-11 per 1000. • no significant difference in males and females; c • spring and winter season
- 8. Predisposing factors - low socioeconomic status overcrowding poor nutrition poor hygiene - genetic predisposition.
- 9. pathogenesis The cytotoxicity theory - streptolysin 0 has a direct cytotoxic effect on mammalian cells in tissue culture. The Immunological theory immunologic cross-reactivity between group A streptococcal co
- 10. PathologyInflammatory Lesions in 1. Heart 2. Brain 3. Joints 4. Skin Aschoff bodies in the atrial myocardium- Swelling, fragmentation of collagen fibres
- 12. aschoff bodies central necrosis surrounded by ring of plump histiocytes aschoff bodies
- 13. T. Duckett Jones Criteria for both initial attack and recurrence 5 major and 4 minor+ Evidence of recent GAS infection first in 1944; various versions; latest in 2015- risk groups and lab criteria low risk-<2 per one lakh school age children; high risk- >2
- 14. major criteria Type to enter a caption.
- 15. newest concept of subclinical carditis- silent carditis- 0-53%/isolated arthritis and/or pure chorea without auscultatory findings of valvular dysfunction
- 16. MINOR CRITERIAS
- 17. Type to enter a caption.
- 18. Type to enter a caption.
- 19. expected clinical courseOnly carditis cause permanent cardiac damage. S/O mild carditis disappear in weeks. Sever carditis may last for 2 to 6 months. Arthritis subside within few days to wks & dose not cause perm Chorea subsides in 6 to 7 months & dose not cause permanent
- 20. treatment Oral salicylates – Patients with typical migratory polyarthritis and those with carditis without cardiomegaly or CCF. •Aspirin -100 mg/kg/24 hr divided qid PO for 3-5 days. followed by 75 mg/kg/24 hr divided qid PO for 4 wk. ANTIBIOTIC THERAPY 10 days of orally administered penicillin or erythromycin. Single intramuscular injection of benzathine penicillin .
- 21. Corticosteroids- Patients with carditis & cardiomegaly or CCF Prednisone - 2 mg/kg/24 hr in 4 divided doses for 2-3 wk. Followed by a tapering of the dose. At the beginning of the tapering of the prednisone dose, aspirin should be started at 75 mg/kg/24 hr in 4 divided doses for 6 wk. Chorea- Phenobarbitone 15 to 30 mg every 6 to 8 hours. Haloperidol (0.01-0.03 mg/kg/ 24 hr divided bid PO) Chlorpromazine(0.5 mg/kg q 4-6 hr PO)
- 23. duration Type to enter a caption.
- 24. thank you