My 2013 PBMI presentation on my thoughts about using data and consumer engagement to shift the pharamcy industry to a industry focused on value as part of the overall health reform efforts.
Business model approaches to survive and thrive ncpdp - finalGeorge Van Antwerp
My presentation for an NCPDP educational event on 11/2/10 regarding the future of pharmacy. I focus on how technology is creating challenges and opportunities for the pharmacy business model.
I'm giving a presentation on 9/19/13 to 3 CBI conferences - Point of Care Summit, Retail Strategy Summit, and Strategic Distribution Planning for Specialty. The topic is how retail pharmacy can serve as the Digital Patient Home in the future. This highlights the emerging opportunity, what some companies are doing, and some of the emerging technology and trends.
Engaging the hard_to_engage_through_innovative_channelsGeorge Van Antwerp
A presentation from the Care Continuum Alliance (CCA) that I gave with Aetna 2 years ago. I found it posted online and decided to share it.
http://www.carecontinuumalliance.org/theforum11/Presentations/Engaging_the_Hard_to_Engage_Through_Innovative_Channels.pdf
Business model approaches to survive and thrive ncpdp - finalGeorge Van Antwerp
My presentation for an NCPDP educational event on 11/2/10 regarding the future of pharmacy. I focus on how technology is creating challenges and opportunities for the pharmacy business model.
I'm giving a presentation on 9/19/13 to 3 CBI conferences - Point of Care Summit, Retail Strategy Summit, and Strategic Distribution Planning for Specialty. The topic is how retail pharmacy can serve as the Digital Patient Home in the future. This highlights the emerging opportunity, what some companies are doing, and some of the emerging technology and trends.
Engaging the hard_to_engage_through_innovative_channelsGeorge Van Antwerp
A presentation from the Care Continuum Alliance (CCA) that I gave with Aetna 2 years ago. I found it posted online and decided to share it.
http://www.carecontinuumalliance.org/theforum11/Presentations/Engaging_the_Hard_to_Engage_Through_Innovative_Channels.pdf
Better Together 2019 Patient Services Survey - Condition Resultsaccenture
Accenture Life Sciences online survey of 4,000 patients across four countries and three conditions reveals how patients use and value services from patient organizations. Explore the unique differences by condition. Visit https://accntu.re/2Y9CGqw to learn more.
On the 15th April, Creation Healthcare presented the winners of the Healthcare Engagement Strategy Awards 2010 at the Hilton Park Lane in London, United Kingdom.
Better Together: 2019 Patient Services Survey - Country Resultsaccenture
Accenture Life Sciences survey of 4,000 patients across four countries and three conditions reveals how patients use and value services from patient organizations. Explore the unique differences by country. Visit https://accntu.re/2Y9CGqw to learn more.
Trendwatchers from around the world came together to identify the big shifts critical to pharmaceutical brands and healthcare marketers.
What's inside: 2016 will be the year an old debate reignites and simple digital tools fuel an incredible new era of clinical study. The patient journey will be rerouted and the tug of war at the point of care will get much more intense. Caregiving will approach a cliff, healthcare teams will get bigger, and patients will come to the exam room with new expectations. The science of motivation will face a crossroads and you’ll probably lose you Fitbit.
2015 Health Trends: New challenges for a changing industry
In the second of their 4-part annual trend report series, GSW takes a closer look at healthcare. From evolutions in doctor-patient relationships to strategies in benefit design to the changing mind-set of physicians, a new landscape takes shape.
Evaluating the Brand Value of Healthcare EntitiesPYA, P.C.
PYA Principal Jim Lloyd co-presented with PYA colleague Anna Bhat at the NACVA and Consultants Training Institute’s (CTI) Advanced Healthcare Valuation and Consulting Symposium, December 12-13, 2014, on the topic, “Evaluating the Brand Value of Healthcare Entities,” providing a comprehensive overview regarding:
Healthcare affiliations in which “brand” is a key factor.
Detailed discussion regarding healthcare entity brands.
Methodologies commonly used to value brands.
Evaluating a healthcare entity’s brand strength.
Capitalizing on your entity’s brand.
Healthcare Management PowerPoint Presentation Slides is designed especially for the medical industry professionals. Use this PPT slideshow to showcase all the essentials of healthcare administration with a dash of visual brilliance. Demonstrate the key trends and vital stats of the healthcare industry through our content-driven PowerPoint theme. Communicate details about global healthcare economy, and global spending stats. Illustrate the key demand and supply drivers associated with public health management. Employ our audience-friendly medical administration PPT template deck to elucidate stakeholders in the public health system. Cutting-edge graphics and innovative data visualization designs simplify the explanation. Use diagrams featured in this PowerPoint presentation to describe essential public health services. You will also find infographic-style designs to help elaborating concepts like hospital and corporate tie-ups. Utilize the Venn diagram to emphasize the pharma company operating model. Convey the research and development protocol followed in the pharmaceutical industry. Our comprehensive PPT layout contains oodles of other core aspects of hospital management. This includes cost accounting, financial management, data analysis, strategic planning, marketing, and KPI metrics and dashboards. So, hit the download button and captivate your audience. Our Healthcare Management PowerPoint Presentation Slides are topically designed to provide an attractive backdrop to any subject. Use them to look like a presentation pro. https://bit.ly/3lZSJyR
How do we see the healthcare's digital future and its impact on our lives?Jane Vita
"Healthcare is undergoing major changes spurred on by, but not limited to, technology.
Digitalisation is changing the way we think about health, what taking care of it really entails, our personal role in healthcare systems and the way we interact with technology in the context of health.
In many ways, we are entering a post-institutional age of increased personal responsibility, which presents healthcare service providers and other players in the field with major opportunities and great risks. Technology has the potential to empower people and help them become more active in the management of their and their families’ health. This will change the relationship of the patient and the caregiver in profound ways." Mirkka Länsisalo
A co-creation with Mirkka Läansisalo and Sala Heinänen, at Futurice.
Reaching Out, Inviting In: How Medical Call Centers Can Give Hospitals an Edg...TinaMinnick
Certainly the advent of value‐based purchasing attaches a persuasive incentive for improved core measures and HCAHPS performance, but as any hospital that has experienced a negative letter to the editor or defaming remark on a website will attest, the hard and soft costs of patient satisfaction can impact more than just the bottom line. Forward‐thinking organizations not only seek to understand the relationship between patient communications and satisfaction,they are forging it.
In recent years, medical device manufacturers have embarked on an acquisition binge. We’ve seen a series of blockbuster deals as well as numerous smaller transactions. This M&A bonanza has been sparked in part by the belief that absolute scale creates competitive advantage.
But does it? In many other industries, we find a clear correlation between overall scale and profitability. Classic strategy has long focused on building scale because larger companies tend to wield more influence with customers and have a greater ability to maintain pricing discipline. They also benefit from the most accumulated experience with driving down costs and can spread costs over the widest base of business.
Yet in medtech, the correlation between industry scale and profitability is quite weak. Instead, Bain research shows that profitability is more a function of category leadership than overall scale.
Evolve the life insurance value proposition from compensation to wellness to drive relevancy and growth.
Read more: https://www.accenture.com/ca-en/insight-livening-up-life-insurance
10 most prominent telehealth solution providers in 2021insightscare
In this issue of Insights Care, we bring forth the efforts of “10 Most Prominent Telehealth Solution Providers in 2021” that ensured everyone had access to medical consultation.
White Paper - Internet Marketing Strategies For The Medical Device Industryjerryme5
This is a White Paper that I wrote, while employed at Exemplum, that talks about various marketing strategies that medical device companies can use to leverage the Internet to market their products more effectivelty.
Ideas from MediaPost's Marketing for Health ConferenceGSW
This week, we had the opportunity to attend MediaPost’s first annual Marketing Health conference. Thirty-eight speakers – including our own Ritesh Patel and Leigh Householder – from the top agencies and brands in our industry took to the stage to talk about big shifts in digital possibilities and fast-changing consumer expectations. Inside, you’ll find a quick-scan summary of the conference’s content, including short stories, big data points, memorable quotes and even a few share-worthy charts.
Digital Health Funding 2014 Midyear Report by @Rock_HealthRock Health
A summary of the companies, investors and themes that drove digital health funding to a record $2.3B only halfway through 2014, exceeding the entire 2013 total. Includes details on crowdfunding, exits, and digital health in the public markets, encompassing our new index of publicly-traded digital health companies. Purchase this report here: https://gumroad.com/l/WURST
Updated on July 21, 2014 to reflect final Q2 data on venture funding and deals.
Better Together 2019 Patient Services Survey - Condition Resultsaccenture
Accenture Life Sciences online survey of 4,000 patients across four countries and three conditions reveals how patients use and value services from patient organizations. Explore the unique differences by condition. Visit https://accntu.re/2Y9CGqw to learn more.
On the 15th April, Creation Healthcare presented the winners of the Healthcare Engagement Strategy Awards 2010 at the Hilton Park Lane in London, United Kingdom.
Better Together: 2019 Patient Services Survey - Country Resultsaccenture
Accenture Life Sciences survey of 4,000 patients across four countries and three conditions reveals how patients use and value services from patient organizations. Explore the unique differences by country. Visit https://accntu.re/2Y9CGqw to learn more.
Trendwatchers from around the world came together to identify the big shifts critical to pharmaceutical brands and healthcare marketers.
What's inside: 2016 will be the year an old debate reignites and simple digital tools fuel an incredible new era of clinical study. The patient journey will be rerouted and the tug of war at the point of care will get much more intense. Caregiving will approach a cliff, healthcare teams will get bigger, and patients will come to the exam room with new expectations. The science of motivation will face a crossroads and you’ll probably lose you Fitbit.
2015 Health Trends: New challenges for a changing industry
In the second of their 4-part annual trend report series, GSW takes a closer look at healthcare. From evolutions in doctor-patient relationships to strategies in benefit design to the changing mind-set of physicians, a new landscape takes shape.
Evaluating the Brand Value of Healthcare EntitiesPYA, P.C.
PYA Principal Jim Lloyd co-presented with PYA colleague Anna Bhat at the NACVA and Consultants Training Institute’s (CTI) Advanced Healthcare Valuation and Consulting Symposium, December 12-13, 2014, on the topic, “Evaluating the Brand Value of Healthcare Entities,” providing a comprehensive overview regarding:
Healthcare affiliations in which “brand” is a key factor.
Detailed discussion regarding healthcare entity brands.
Methodologies commonly used to value brands.
Evaluating a healthcare entity’s brand strength.
Capitalizing on your entity’s brand.
Healthcare Management PowerPoint Presentation Slides is designed especially for the medical industry professionals. Use this PPT slideshow to showcase all the essentials of healthcare administration with a dash of visual brilliance. Demonstrate the key trends and vital stats of the healthcare industry through our content-driven PowerPoint theme. Communicate details about global healthcare economy, and global spending stats. Illustrate the key demand and supply drivers associated with public health management. Employ our audience-friendly medical administration PPT template deck to elucidate stakeholders in the public health system. Cutting-edge graphics and innovative data visualization designs simplify the explanation. Use diagrams featured in this PowerPoint presentation to describe essential public health services. You will also find infographic-style designs to help elaborating concepts like hospital and corporate tie-ups. Utilize the Venn diagram to emphasize the pharma company operating model. Convey the research and development protocol followed in the pharmaceutical industry. Our comprehensive PPT layout contains oodles of other core aspects of hospital management. This includes cost accounting, financial management, data analysis, strategic planning, marketing, and KPI metrics and dashboards. So, hit the download button and captivate your audience. Our Healthcare Management PowerPoint Presentation Slides are topically designed to provide an attractive backdrop to any subject. Use them to look like a presentation pro. https://bit.ly/3lZSJyR
How do we see the healthcare's digital future and its impact on our lives?Jane Vita
"Healthcare is undergoing major changes spurred on by, but not limited to, technology.
Digitalisation is changing the way we think about health, what taking care of it really entails, our personal role in healthcare systems and the way we interact with technology in the context of health.
In many ways, we are entering a post-institutional age of increased personal responsibility, which presents healthcare service providers and other players in the field with major opportunities and great risks. Technology has the potential to empower people and help them become more active in the management of their and their families’ health. This will change the relationship of the patient and the caregiver in profound ways." Mirkka Länsisalo
A co-creation with Mirkka Läansisalo and Sala Heinänen, at Futurice.
Reaching Out, Inviting In: How Medical Call Centers Can Give Hospitals an Edg...TinaMinnick
Certainly the advent of value‐based purchasing attaches a persuasive incentive for improved core measures and HCAHPS performance, but as any hospital that has experienced a negative letter to the editor or defaming remark on a website will attest, the hard and soft costs of patient satisfaction can impact more than just the bottom line. Forward‐thinking organizations not only seek to understand the relationship between patient communications and satisfaction,they are forging it.
In recent years, medical device manufacturers have embarked on an acquisition binge. We’ve seen a series of blockbuster deals as well as numerous smaller transactions. This M&A bonanza has been sparked in part by the belief that absolute scale creates competitive advantage.
But does it? In many other industries, we find a clear correlation between overall scale and profitability. Classic strategy has long focused on building scale because larger companies tend to wield more influence with customers and have a greater ability to maintain pricing discipline. They also benefit from the most accumulated experience with driving down costs and can spread costs over the widest base of business.
Yet in medtech, the correlation between industry scale and profitability is quite weak. Instead, Bain research shows that profitability is more a function of category leadership than overall scale.
Evolve the life insurance value proposition from compensation to wellness to drive relevancy and growth.
Read more: https://www.accenture.com/ca-en/insight-livening-up-life-insurance
10 most prominent telehealth solution providers in 2021insightscare
In this issue of Insights Care, we bring forth the efforts of “10 Most Prominent Telehealth Solution Providers in 2021” that ensured everyone had access to medical consultation.
White Paper - Internet Marketing Strategies For The Medical Device Industryjerryme5
This is a White Paper that I wrote, while employed at Exemplum, that talks about various marketing strategies that medical device companies can use to leverage the Internet to market their products more effectivelty.
Ideas from MediaPost's Marketing for Health ConferenceGSW
This week, we had the opportunity to attend MediaPost’s first annual Marketing Health conference. Thirty-eight speakers – including our own Ritesh Patel and Leigh Householder – from the top agencies and brands in our industry took to the stage to talk about big shifts in digital possibilities and fast-changing consumer expectations. Inside, you’ll find a quick-scan summary of the conference’s content, including short stories, big data points, memorable quotes and even a few share-worthy charts.
Digital Health Funding 2014 Midyear Report by @Rock_HealthRock Health
A summary of the companies, investors and themes that drove digital health funding to a record $2.3B only halfway through 2014, exceeding the entire 2013 total. Includes details on crowdfunding, exits, and digital health in the public markets, encompassing our new index of publicly-traded digital health companies. Purchase this report here: https://gumroad.com/l/WURST
Updated on July 21, 2014 to reflect final Q2 data on venture funding and deals.
This is a long version of what I'm presenting at PCMA on 2/8/12. It includes more data that I'll be sharing and summarizing during my verbal presentation.
My talk during the Digital4 Pharma conference, July 2016 in Greece. My talk described the digital transformation of Takeda with our vision and how Takeda Pharmaceutical explore initiatives and trends in order to provide better services to healthcare professionals. Virtual Reality was one of the experiments which Takeda Hellas implemented in the framework of digital new way of thinking. Key findings are cross-functional collaboration, focus on the objectives and needs of our HCPs. Conclusion: if we benefit from the combination of the technology and traditional marketing aspects then the results will be a good mix of creative and quality actions .
StartUp Health - Private Market Perspectives - Digital Healthcare Innovation ...Healthegy
Presentation by StartUp Health at Digital Healthcare Innovation Summit 2016.
Participant:
Katya Hancock, Director of Strategic Partnerships – StartUp Health
Introduced By:
Tom Salemi, Content Director – Healthegy
Powered by:
Healthegy
For more healthcare innovation
Visit us at Healthegy.com
Digital Strategy for Kosmostrars - Nestle. by "Pretty Fly"Dmitry Zorkin
Презентация команды "Pretty Fly" для кампуса ИКРы 2013г. Данная стратегия была разработана и подготовлена при участии:
Елена Зоркина
Анастасия Шмагина
Максим Корнев
Дмитрий Зоркин
Ролик снятый в поддержку "смерти рекламы" - http://www.youtube.com/watch?v=xBoPeQ0uIOc
Aleksandar Stojanovic shocked and woke up some sleeping marketers, brand directors and communication leaders from the pharma and healthcare industry during his talk at the "Global Pharma Marketing Summit" in 2012, where he enjoed giving some candid real-world advice on "How to crack the corporate piggybank for serious digital investments." On a side note he shared some hints on how to make pharma marketing and brand stories suck less.
What the Shift to Value Means for PharmaceuticalsMedullan
With the transition to value, payers are insisting that pharmaceutical manufacturers deliver real world evidence of their drug’s efficacy before being allowed on formulary. The cost of new specialty treatments has forced companies to bolster and go beyond clinical trial, proving that their drugs improve health outcomes and reduce the cost of care in actual use. Gathering and compiling the myriad of needed data points requires a digital strategy that connects patients, providers, and payers. These comprehensive digital technology platforms are also effective tools for delivering competitive differentiation, better speed to market, and a source for new and expanded revenues.
How Pharma Can Use Digital Health to Drive Value | A Medullan WebinarMedullan
With the shift to value, healthcare payers are insisting that pharmaceutical manufacturers deliver real world evidence of their drug’s efficacy before being allowed on formulary. The cost of new specialty treatments has forced companies to bolster and go beyond clinical trial, proving that their drugs improve health outcomes and reduce the cost of care with real world evidence.
So how do pharmaceutical companies gather these data points and what kind of digital tools should they use?
The healthcare delivery model is being transformed and each stakeholder has an integral part to play in its much needed success. Healthcare delivery organizations, payers, and employers have typically shouldered much of this responsibility, and now patients are being added to the mix as their consumer influence and purchasing power grows. Porter Research President Cynthia Porter will explore this evolution and the industry trends that have turned previously backseat patients into some of healthcare's most powerful drivers.
Presented in April 2012 at Breakthrough 2013 - the Medecision Client Forum
Analytics-Driven Healthcare: Improving Care, Compliance and CostCognizant
In the face of skyrocketing costs, the healthcare industry is addressing inefficiencies by improving data sharing and collaboration across the industry value chain and applying analytics to improve operations and patient outcomes.
This is a deck I created to frame out my vision about healthcare and used in my job search. This is the exciting space in healthcare right now - communications, segmentation, data mining.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The hemodynamic and autonomic determinants of elevated blood pressure in obes...
PBMI 2013 Presentation on Shift From FFS to Value
1. Pharmacy – Data, COEs, Predictive
Models, and Consumer Engagement
George Van Antwerp
VP, Product Development
inVentiv Medical Management
February 2013
2. Caregiver PCP
Patient
Case Manager Pharmacy
Pharmacist Pharma
Health PBM
Insurer
Employer
2
3. My Predictions For 2013
1. Reform will happen.
2. Big Data will be a focus.
3. Physicians grab power through “ACOs”.
4. mHealth will drive innovation and patient engagement.
5. Incentives and gamification will become the norm.
6. Home testing and remote monitoring will increase.
7. Pharmacies will address the PCP shortage.
8. Telemedicine will hit a tipping point.
9. Transparency will empower consumers.
10. Generics will no longer be a focus.
3
4. Learning Objectives
• Explain the pharmacy industry implications of the shift from Fee For
Service to Outcomes Based Contracting
• List examples of how leading edge companies are using technology
and Big Data to embrace this change
• Outline options for PBMs and pharmacies to take a more active role
within the expanded care team with a focus on the Triple Aim of cost,
quality, and consumer experience
4
5. What Is Population Health Management?
Source: Outcomes Guidelines Report Volume 5. (2010). Washington, DC: Care Continuum Alliance
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6. Adherence Is Our Foundation For Growing The
Role Of Pharmacy
• Adherence has been shown to drive lower medical costs1:
– CHF savings $8,881 / year
– Hypertension $4,337 / year
– Diabetes $4,413 / year
– Dyslipidemia $1,860 / year
• Adherence has also been shown to reduce absenteeism by 7 days
per year per patient with chronic diseases (~$1,700 in savings) 2
• Additionally, there is a significant gap between perceived adherence
(which is high) and actual adherence (which is low) signaling a need
for increased intervention3
1 – Health affairs article - http://www.cimit.org/images/events/ciw/Adherence-Health-Affairs.pdf
2 - http://www.drugstorenews.com/article/cvs-caremark-research-finds-link-between-medication-adherence-employee-productivity
3 – Gap in perceived versus actual adherence identified in 2011 Express Scripts Drug Trend Report
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7. Growth Requires Integration Of
Medical And Rx Data
Source: PBMI 2012 Specialty Drug Report, Prime Therapeutics 2012 Drug Trend Report
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8. The Value Of Pharmacy On Quality Is
Increasingly Being Recognized
Source: CVS Caremark 2012 Insights Report
8
9. Evidence-based medicine Accountable Care
Warning:
Bundled
Payments New Paradigm VBID
Ahead
Comparative Effectiveness
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10. Pay For Value Not Service
“Fee-for-service payments drive up health care costs and
potentially lower the value of care for two main reasons.
First, they encourage wasteful use, especially of high-cost
items and services. Second, they do nothing to align
financial incentives between different providers.”
Quote from http://www.americanprogress.org/issues/healthcare/report/2012/09/18/38320/alternatives-to-
fee-for-service-payments-in-health-care/
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11. Employer Premiums Tied To Health Outcomes
12%
of employers penalized or
30%
of difference in premiums
incented employees based on allowed by the ACA based on
outcomes in 2011 according to “meeting employer defined
Towers Watson health targets”
http://www.towerswatson.com/united-states/press/5708
http://www.huffingtonpost.com/2012/06/29/health-plans-obese-smokers-supreme-court_n_1636139.html
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12. Outcomes Based Thinking Creates A New
Way Of Looking At The Value Chain
“Dr. Google” Population
Physician
mHealth Pharmacy Health
Encounter
P2P Mgmt
Where did they go from information?
Feeling Sick What information or apps did you prescribe? Cure
Annual Exam How did you improve their PAM score? Remission
Were they satisfied with their experience? Survivorship
Did you pull in their caregiver?
What are their goals?
How will they judge improvement?
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13. People Aren’t A Disease
I can’t wait to lower
X
my A1c by 2 points.
That would be
great!
I hope I’m mobile
enough to take my
grandkids to Disney!
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14. Understanding Consumers Allows For
Information To Be “Prescribed”
Go to this
website
Watch this video
Download this
mobile app
Join this
community
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15. Not about access but about outcomes
Shift from Rx costs to total costs
Transition away from rebates Look at quality of life
Physician and pharmacist collaboration
De-emphasize eRx for PHR and EMR
15
16. Lowest Most
Trend Generics
Lowest
Best
Error
Rebates
Rate
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21. Examples Of True Outcomes Based Contracting In
Pharmacy Are Limited
• Merck – Cigna Diabetes
• Rebif – Prime Therapeutics MS
• Sanofi – Health Alliance Osteoporosis
• Pfizer – Humana Alzheimers, pain, cardiovascular
• Bayer – Denmark Levitra
• J&J– UK Velcade
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22. Cigna-Merck Diabetes Contract
• The two-part contract with Merck provided discounts if CIGNA
customers with diabetes lowered their blood sugar levels,
regardless of the medication they were taking, and also provided
for additional discounts if people who were prescribed Merck’s drugs
Januvia and Janumet took their medications according to their physicians’
instructions. Discounts will be shared in various ways with CIGNA employer
clients.
• Kang said that the idea of paying less for medications if they are successful
is counter-intuitive and not at all like other performance-based contracts on
the market today. What makes this unique approach so successful is that
everyone’s incentives line up behind helping customers keep their diabetes
under control. CIGNA’s costs are lowered, medication adherence increases,
resulting in health benefits for individuals and improved productivity and
lower health care costs for their employers.
http://www.vbhealth.org/outcomes-based-contracting-2/cigna-merck-obctm-delivers-on-vbbd-dividends
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24. Prime Therapeutics CareCentered Contracting
• Through CareCentered Contracting, pharmaceutical companies
agree to either refund the cost of the drug for patients whose
medication does not work as expected, such as an osteoporosis
patient who suffers a fracture, or cover the cost of treating such
an event. The health outcomes and medication adherence of
patients are not typically factors in pricing negotiations.
• CareCentered Contracting includes these components in order
to reduce uncertainty about the effectiveness of medications and
possible side effects for members and increase accountability
between pharmaceutical manufacturers and health plans.
http://blog.primetherapeutics.com/blog/outcomes-based-contracting
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31. Do You Really Think That 99 Seconds Is Enough
Time For A Patient To Understand Their Drug?
http://www.thedoctorweighsin.com/what-physicians-spend-10-mins-of-every-conversation-doing-can-drive-or-diminish-patient-engagement/
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32. What Are Some Opportunities For Outcomes-
Based Alignment?
• PBMs contracting with retail pharmacies based on
patient satisfaction or adherence
• Employers contracting with PBMs based on
improvements in overall medical spend
• Linking mail order rates to the patient experience based
on a metric like Net Promoter Score
• Replacing rebate contracting with outcomes based
contracting
• Paying for gaps-in-care addressed at the POS
• Linking employee engagement to lower health
premiums
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36. Walgreens’ WellTransitions Program
• Medication review – pharmacists review patients’ prescriptions upon
admission to the hospital and at discharge; check for potential
interactions and simplification of medication regimen
• Bedside medication delivery – Walgreens pharmacy staff member
delivers medication the patient will need to take after discharge to the
patient’s room and offers medication education and instruction
• Patient counseling – pharmacists provide medication counseling to
both the patient and caregiver and work in close communication with
the medical staff
• Regularly-scheduled follow-up calls – pharmacists conduct regular calls
to follow up on patient progress, discuss regimen and answer any
questions or concerns
• 24/7 pharmacist support – pharmacy staff is available to answer patient
questions 24/7 either over the phone or online
http://news.walgreens.com/article_display.cfm?article_id=5648
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40. Shifting The Pharmacy / Pharmacist Role To Be Part
Of The Expanded Care Team Is Critical
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41. Learning Objectives
• Explain the pharmacy industry implications of the shift from Fee For
Service to Outcomes Based Contracting
– Mx and Rx integration of data
– New metrics
– MD collaboration
• List examples of how leading edge companies are using technology
and Big Data to embrace this change
– Predictive adherence models
– Pharma contracting around outcomes
• Explore options for PBMs and pharmacies to take a more active role
within the expanded care team with a focus on the Triple Aim of cost,
quality, and consumer experience
– Prevention
– Engagement
– Re-admissions
– mHealth
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42. Thank You
George Van Antwerp
VP, Product Development
inVentiv Medical Management
george.vanantwerp@inventivMM.com
www.georgevanantwerp.com
@gvanantwerp
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