John Donahue is a 45-year-old high school principal who has suffered from panic attacks for 15 years. His symptoms include intense fear, heart palpitations, nausea, dizziness, and fears of losing control. He meets the criteria for panic disorder with agoraphobia. John likely developed this disorder due to genetic and social factors like his family history of anxiety disorders and stressful life events. His condition is maintained by safety behaviors, cognitions about panic attacks being dangerous, and anticipatory anxiety. Treatment involves cognitive behavioral therapy and exposure therapy, with John gradually facing feared situations to overcome his avoidance.