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Evaluating a Guideline Treatment of panic disorder and Agoraphobia: clinical practice guideline (CPG)
What is EBM? Best Research Evidence Patient Values Clinical Expertise
Levels of evidence
National Health and Medical Research Council (NHMRC) levels of evidence  I Evidence obtained from a systematic review of all relevant randomised controlled trials  II Evidence obtained from at least one properly designed randomised controlled trial  III - 1 Evidence obtained from well-designed pseudorandomised controlled trials (alternate allocation or some other method)  III - 2 Evidence obtained from comparative studies (including systematic reviews of such studies) with concurrent controls and allocation not randomised, cohort studies, case-control studies, or interrupted time series with a control group  III - 3 Evidence obtained from comparative studies with historical control, two or more single arm studies, or interrupted time series without a parallel group  IV Evidence obtained from case series, either post-test or pretest/ post-test
Evidence Pyramid
Evidence Pyramid
Appraisal of Guidelines Research & Evaluation ( AGREE  )
Appraisal of Guidelines Research & Evaluation: Domains ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Appraisal of Guidelines Research & Evaluation:  CRITERIA ,[object Object]
A guide to the Development, Evaluation and Implementation of Clinical Practice Guidelines: NHMRC 1999 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Two Components of any Guideline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Limitations of Evidence ,[object Object],[object Object],[object Object],[object Object]
Clinical Practice Guidelines Depression Schizophrenia Bipolar Disorder Deliberate Self Harm Anorexia Nervosa Panic Disorder &  Agoraphobia Clinician Consumer
System Application of nationally developed CPGs Systematic Review  (Multi Disciplinary Panel) Draft CPG National Endorsement  (AUS/ NZ) Decision to Diffuse, disseminate  & develop implementation programs Local Adaptation Decision Support  System CPD  Community/ Media/ Consumer
Applying Guideline in Clinical Practice CPG to assess  Current practice Local Problem  Solving Provide Guide to pts
Local problem solving ,[object Object],[object Object],[object Object],[object Object],[object Object]
Applying Guideline in Clinical Practice PLAN MONITOR REVIEW ACT
Panic disorder and agoraphobia
Australian and New Zealand clinical practice guidelines for the treatment of panic disorder and agoraphobia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Australian and New Zealand clinical practice guidelines for the treatment of panic disorder and agoraphobia :  Method ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Australian and New Zealand clinical practice guidelines for the treatment of panic disorder and agoraphobia : Summary version by Andrews et al  March-2003) ,[object Object],[object Object],[object Object],[object Object],[object Object]
American Vs Aussie  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Appraisal of Guidelines Research & Evaluation:  Domains ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Would you join a guideline development group? ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Evaluating A Guideline Panic Disorder

  • 1. Evaluating a Guideline Treatment of panic disorder and Agoraphobia: clinical practice guideline (CPG)
  • 2. What is EBM? Best Research Evidence Patient Values Clinical Expertise
  • 4. National Health and Medical Research Council (NHMRC) levels of evidence I Evidence obtained from a systematic review of all relevant randomised controlled trials II Evidence obtained from at least one properly designed randomised controlled trial III - 1 Evidence obtained from well-designed pseudorandomised controlled trials (alternate allocation or some other method) III - 2 Evidence obtained from comparative studies (including systematic reviews of such studies) with concurrent controls and allocation not randomised, cohort studies, case-control studies, or interrupted time series with a control group III - 3 Evidence obtained from comparative studies with historical control, two or more single arm studies, or interrupted time series without a parallel group IV Evidence obtained from case series, either post-test or pretest/ post-test
  • 7. Appraisal of Guidelines Research & Evaluation ( AGREE )
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  • 13. Clinical Practice Guidelines Depression Schizophrenia Bipolar Disorder Deliberate Self Harm Anorexia Nervosa Panic Disorder & Agoraphobia Clinician Consumer
  • 14. System Application of nationally developed CPGs Systematic Review (Multi Disciplinary Panel) Draft CPG National Endorsement (AUS/ NZ) Decision to Diffuse, disseminate & develop implementation programs Local Adaptation Decision Support System CPD Community/ Media/ Consumer
  • 15. Applying Guideline in Clinical Practice CPG to assess Current practice Local Problem Solving Provide Guide to pts
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  • 17. Applying Guideline in Clinical Practice PLAN MONITOR REVIEW ACT
  • 18. Panic disorder and agoraphobia
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