Central face begins to develop by 4th week, when olfactory placodes appear on both sides of the frontonasal process.
Gradually both placodes develop to form the median and lateral nasal process.
Upper lip is formed by 6th week by fusion of two median nasal processes in midline and the maxilllary process of the 1st branchial arch.
PRE-NATAL GROWTH AND DEVELOPMENT OF PALATEFormation of primary and secondary palate
Elevation of palatal shelves
Fusion of palatal shelves
Central face begins to develop by 4th week, when olfactory placodes appear on both sides of the frontonasal process.
Gradually both placodes develop to form the median and lateral nasal process.
Upper lip is formed by 6th week by fusion of two median nasal processes in midline and the maxilllary process of the 1st branchial arch.
PRE-NATAL GROWTH AND DEVELOPMENT OF PALATEFormation of primary and secondary palate
Elevation of palatal shelves
Fusion of palatal shelves
This Presentation includes systematic compilation of the anatomy, physiology, biochemistry and pathology related to saliva and salivary glands. it also mentions about the role of saliva in dentistry. Any additions or mistakes are welcome!
Please do leave your comments and let me know if the presentations has helped you!
The presentation is available on request. Mail me at apurvathampi@gmail.com
Coronal and radicular pulp
Apical foramen
Accessory canal
Functions of dental pulp
Components of dental pulp
Functions of pulpal extracellular matrix
Organization of cells in the pulp
The principle cells of the pulp
The pathways of collagen synthesis
Matrix and ground substances
Vasculature and lymphatic supply
Innervation of Dentin- pulp complex
Disorders of the dental pulp
Advances in pulp vitality testing
This Presentation includes systematic compilation of the anatomy, physiology, biochemistry and pathology related to saliva and salivary glands. it also mentions about the role of saliva in dentistry. Any additions or mistakes are welcome!
Please do leave your comments and let me know if the presentations has helped you!
The presentation is available on request. Mail me at apurvathampi@gmail.com
Coronal and radicular pulp
Apical foramen
Accessory canal
Functions of dental pulp
Components of dental pulp
Functions of pulpal extracellular matrix
Organization of cells in the pulp
The principle cells of the pulp
The pathways of collagen synthesis
Matrix and ground substances
Vasculature and lymphatic supply
Innervation of Dentin- pulp complex
Disorders of the dental pulp
Advances in pulp vitality testing
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Surgical anatomy of palate by Dr. Amit Suryawanshi .Oral & Maxillofacial Su...All Good Things
Description:
Hi. This is Dr. Amit T. Suryawanshi. Oral & Maxillofacial surgeon from Pune, India. I am here on slideshare.com to share some of my own presentations presented at various levels in the field of OMFS. Hope this would somehow be helpful to you making your presentations. All the best & your replies are welcomed!
Surgical anatomy of palate. by Dr. Amit T. Suryawanshi, Oral Surgeon, Pune All Good Things
Hi. This is Dr. Amit T. Suryawanshi. Oral & Maxillofacial surgeon from Pune, India. I am here on slideshare.com to share some of my own presentations presented at various levels in the field of OMFS. Hope this would somehow be helpful to you making your presentations. All the best.
Development of palate /certified fixed orthodontic courses by Indian dental a...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
My soft palate / dental implant courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
In this seminar we will learn about the development or tongue and oropharynx starting with Pharynx, its Boundaries and Parts, Structure, layers, muscles of pharynx. Then cover the Blood supply, nerve supply and Lymphatic drainage pharynx.
We will also read about Oropharynx and its Relations,
Waldeyer’s lymphatic ring and Physiology of deglutition
Tongue, its Parts, External features and Papillae of the tongue
Muscles of the tongue, Blood supply of the tongue , Arterial and nerve supply, Venous and lymphatic drainage. Development of the tongue and Physiology of taste sensation
Developmental disturbances of the tongue and Periodontal implications are other parts of this seminar
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
2. Content
Introduction
Development of palate
Hard palate
Soft palate
Muscles
Blood supply
Nerve supply
funtions
Clinical consideration
3. Introduction
Palate is the roof of the mouth. It separates the oral
cavity from the nasal cavity
Lies in the roof of the oral cavity
Has two parts:
Hard (bony) palate anteriorly
Soft (muscular) palate posteriorly
4. Development of the Palate
Initially, during the 6th week of
intrauterine development, there
is a common oro-nasal cavity
bounded anteriorly by the
primary palate and occupied
mainly by the developing
tongue
5. The medial part is also known as the primary palate
because it develops first and is a floor to the nasal pits.
Lateral palatine process develop from the maxillary
tissues laterally & grow to midline.
6. The primary palate is formed by
the merging of the two median
nasal processes
7. Between the 7th and 8th weeks of
development, formation of the
secondary palate occurs
8. Formation of the palate involves
the fusion of two processes: the
right and left maxillary processes
and the medial nasal process
9. The median nasal process grows
downward and forward to form
the nasal septum
10. The growth into the
stomodeum from the
inside of the maxillary
processes is called the
right and left lateral
palatine processes,
which at first grows
downward to the
elevated tongue
11. As a result of the enlargement of
the mandible and a change in
the degree of flexion of the fetus
head, the tongue drops to the
floor of the stomodeum
12. When the tongue is removed
from the path of the growing
lateral palatine processes, the
processes are straightened to a
horizontal position
13. Then the lateral
palatine processes
grows medially at the
midline and fuse with
each other and with
the lower border of the
nasal septum to give
rise to the hard and soft
palate
14. At their anterior
borders, they meet and
fuse with the posterior
border of the
premaxillary growth
(primary palate)
The structure thus
formed is at once the
roof of the oral cavity
and the floor of the
nasal cavity
15.
16.
17. Hard Palate
Lies in the roof of the oral
cavity
Forms the floor of the
nasal cavity
Formed by:
Palatine processes of
maxillae in front
Horizontal plates of
palatine bones behind
Bounded by alveolar
arches
18. Posteriorly, continuous
with soft palate
Its undersurface
covered by
mucoperiosteum
Shows transverse ridges
in the anterior parts
19.
20. SOFT PALATE
movable muscular fold
suspended from post border of
hard palate
Separates nasopharynx from
oropharynx
Traffic controller
2 surfaces
2 borders
2 folds of mucous membrane
21.
22. Soft Palate
Covered on its upper and lower
surfaces by mucous membrane
Composed of:
Muscle fibers
An aponeurosis
Lymphoid tissue
Glands
Blood vessels
Nerves
23. Palatine Aponeurosis
Fibrous sheath
Attached to posterior
border of hard palate
Is flattened tendon of
tensor velli palatini
Splits to enclose
musculus uvulae
Gives origin & insertion to
palatine muscles
24. Muscles
Tensor veli palatini
Origin: spine of
sphenoid;,scaphoid fossa,
auditory tube
Insertion: forms palatine
aponeurosis which is attached
to
(a) Posterior border of hard
palate
(b)Inf surface of palate behind
palatine crest
Action: Tenses soft palate,opens
auditory tube
25. Muscles
Levator veli palatini
Origin: petrous temporal bone,
auditory tube, Enters pharynx by
passing over the upper concave
margin of sup constrictor
Insertion: palatine aponeurosis
Action: Raises soft palate also
dilates auditory tube
27. Muscles
Palatopharyngeus
Origin: Ant Fasciculus
Post border of hard palate
Post fasciculus:palatine
aponeurosis
Insertion: posterior border of
thyroid cartilage
Action: Elevates wall of the
pharynx
29. Blood Supply
Greater palatine branch of the maxillary artery
Ascending palatine, branch of the facial artery
Palatine br of Ascending pharyngeal, branch of
the external carotid artery
VEINS;
Pterygoid and tonsillar plexus of veins
Lymphatics
Upper deep cervical&retropharyngeal
30. Sensory Nerve Supply
General Sensory:Mostly by the maxillary nerve
through its branches:
Middle lesser palatine nerve
Posterior lesser palatine nerve
Special Sensory:For taste sensations: lesser
palatine nerves:greater petrosal nerve :
geniculate ganglion :facial nerve nucleus of
solitary tract.
Secretomotor;Lesser palatine nerves Derived from
sup. salivatory nucleus Travel through greater
petrosal nerves.
31. Motor Nerve Supply
All the muscles, except tensor veli palatini, are
supplied by the:
Pharyngeal plexus
Tensor veli palatini supplied by the:
Nerve to medial pterygoid, a branch of the
mandibular division of the trigeminal nerve
32. Movements & functions of Soft palate
Controls 2 gates
Isolates mouth from Oropharynx during chewing
Separates Oropharynx from nasopharynx
Vary degree of closure of pharyngeal isthmus to modify
quality of voice during coughing and sneezing
34. Clinical Considerations
Cleft palate – is the result of the
non-fusion of the 2 palatine
processes and the inferior
border of the nasal septum
Uranoschisis – cleft hard palate
35. Torus palatinus
Is a bony protrusion on the
palate.
Palatal tori are usually present
on the midline of the hard
palate.
42. Signs and symptoms
-open connection between the oral cavity and nasal cavity is called velopharyngeal
inadequacy (VPI).
-air leaks into the nasal cavity resulting in a hypernasal voice resonance and nasal emissions
while talking.
Treatment
treatment options include speech therapy, prosthetics, augmentation of the posterior
pharyngeal wall, lengthening of the palate, and surgical procedures
43. Paralysis of the soft palate
The pharyngeal isthmus can not be
closed during swallowing and speech
Nasal regurgitation
Nasal twang
Flattening of Palatoglossal arch
44. Incisive Canal Cyst
Incisive canal cysts usually present as asymptomatic
palatal swellings
45. Smoker’s palate/ Stomatitis nicotina
it is a diffuse white patch on the hard palate, usually
caused by tobacco smoking, usually pipe or cigar
smoking.
It is a painless, and it is caused by a response of the
palatal oral mucosa to chronic heat
46. REFREANCES
GRAY’S ANATOMY 40TH EDITION
ATLAS OF HUMAN ANATOMY-NETTER 2006
WHEELERS’S DENTAL ANATOMY
TEN-CATES’S – ORAL HISTOLOGY
ORAL DEVLOPMENET AND HISTOLOGY, JAMES K AVERY, 3RD EDITION
NEVILLE, ORAL & MAXILLOFACIAL PATHOLOGY
47. Thanking you
Guided by-
Dr. Basavaraj kallalli ( Dean & HOD)
Dr. Kamala.R .(Professor)
Dr. Shurthi. Patil (Sr. Lecturer)
Dr. Ankur (sr. lecturer)
Dr. piyush (sr. lecturer)
Presented by :-
Parthsarthi gautam
P.G student
Narsinhbhai patel dental college &
hospital