Ovorest Presentation.pptx
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This document summarizes the composition and use of the Ovorest birth control pill. The 21 white pills each contain 0.15 mg of levonorgestrel and 0.03 mg of ethinyl estradiol for contraception. The 7 brown pills are inert. Levonorgestrel is a widely used progestin that works by inhibiting ovulation and thickening cervical mucus. Ovorest can be used for contraception, treatment of abnormal uterine bleeding, and painful periods, but is contraindicated in several medical conditions. Patients take one white pill daily for 21 days followed by one brown pill daily for 7 days, with withdrawal bleeding typically occurring 2-4 days after the last white pill. Common side
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Ovorest Presentation.pptx
- 1. Brand Name Pill/ Cycle Composition/Pill White Pill Brown Pill Ovorest 21+7 Ethinyl Estradiol BP 0.03 mg + Levonorgestrel BP 0.15 mg Ferrous Fumarate BP 75.0 mg
- 2. • The 21 white active tablets contain 0.15 mg Levonorgestrel and 0.03 mg Ehinylestradiol each. • The 7 brown tablets are inert. • Each brown tablet contains Ferrous Fumarate BP 75 mg.
- 3. Levonorgestrel is a second-generation progestin. It is the most widely prescribed birth control progestin worldwide.
- 4. PHARMACOLOGICAL ACTION • Oral contraceptives of the combination type act by a multiplicity of mechanisms. • Ovulation is inhibited by suppression of gonadotropin release, particularly the mid-cycle peaks and the viscosity of the cervical mucus is increased impairing sperm penetration, and an endometrium, less receptive for implantation is formed.
- 5. INDICATIONS • A low dose oral contraceptive pill. • OVOREST is indicated for fertility control in women and for the control of cases of dysfunctional uterine bleeding (changes in hormones that directly affect the menstruation cycle, the condition is called dysfunctional uterine bleeding (DUB).) • Symptomatic treatment of primary dysmenorrhea (painful periods) where contraception is also desired.
- 6. CONTRA-INDICATIONS • Impaired liver function • Severe Migraine • Coronary-artery disease and undiagnosed vaginal bleeding. • Epilepsy, asthma, hypertension, depression or states in which fluid retention occur. • Must be avoided in known or suspected pregnancy.
- 7. DOSAGE • OVOREST tablets must be taken as directed and at intervals not exceeding 24 hours. • Patients should be instructed to take the tablets at the same time every day, preferably after the evening meal or at bedtime. • During the first cycle of administration, the patient is instructed to take one white tablet daily for 21 consecutive days beginning on Day 1 of her menstrual cycle, i.e. the first day of bleeding. • One brown inert tablet is taken daily for the next 7 consecutive days. • Withdrawal bleeding should usually occur 2 to 4 days after the last white tablet is taken.
- 8. SIDE-EFFECTS • Nausea and/or vomiting • Temporary slight intermenstrual bleeding • Headache Change in libido • Change in menstrual flow • Depressive moods • Breast changes including tenderness and enlargement.
- 9. Benefits of less androgenic effects: • No or improves – Acne • Hirsutism (unwanted hair growth) • Less or no weight gain • Favorable influences on lipid profile
- 10. Key Selling Point • Efficient low dose oral contraceptive pill • Effective in reducing dysfunctional uterine bleeding • Effective in reducing dysmenorrhoea
- 11. Thanks