Omega-3 fatty acids are essential fatty acids, a class of nutrients needed for our body to function normally.
These are the fats of life which help our cells to function properly.
Omega-3 cannot be produced be our body and should be supplied through the diet.
There are 2 very important types of Omega 3 acids , namely EPA and DHA, which have amazing health benefits.
KALOFLAX 90 Softgel : A Herbal Anti Oxidant & a good source of Omega 3, 6 & 9
See: http://nirogam.com/product_detail/16/Kaloflax-90-Softgels
For more information, please see the link below : http://herbscancure.com/blog/omg-facts-about-omega-3/
Omega -3 & Omega -6 Fatty acids and their Health EffectsZahir Khan
Omega-3 fatty acids are essential fatty acids, a class of nutrients needed for our body to function normally.
These are the fats of life which help our cells to function properly.
Omega-3 cannot be produced be our body and should be supplied through the diet
There are 3 very important types of Omega 3 acids
1.Alpha-linolenic acid (ALA)
2.Eicosapentaenoic acid (EPA)
3.Docosahexaenoic acid (DHA)
which have amazing health benefits
Omega 3 plays a major role in a number of functions in our body. Here are they:-
Relaxation and contraction of muscles
Blood clotting
Digestion
Fertility
Cell division
Growth
Movement of calcium and other substances in and out of cells.
Omega -3 & omega -6 acids and their health effects.Zahir Khan
Omega-3 fatty acids are essential fatty acids, a class of nutrients needed for our body to function normally.
These are the fats of life which help our cells to function properly.
Omega-3 cannot be produced be our body and should be supplied through the diet
Omega-3 fatty acids are essential fatty acids, a class of nutrients needed for our body to function normally.
These are the fats of life which help our cells to function properly.
Omega-3 cannot be produced be our body and should be supplied through the diet.
There are 2 very important types of Omega 3 acids , namely EPA and DHA, which have amazing health benefits.
KALOFLAX 90 Softgel : A Herbal Anti Oxidant & a good source of Omega 3, 6 & 9
See: http://nirogam.com/product_detail/16/Kaloflax-90-Softgels
For more information, please see the link below : http://herbscancure.com/blog/omg-facts-about-omega-3/
Omega -3 & Omega -6 Fatty acids and their Health EffectsZahir Khan
Omega-3 fatty acids are essential fatty acids, a class of nutrients needed for our body to function normally.
These are the fats of life which help our cells to function properly.
Omega-3 cannot be produced be our body and should be supplied through the diet
There are 3 very important types of Omega 3 acids
1.Alpha-linolenic acid (ALA)
2.Eicosapentaenoic acid (EPA)
3.Docosahexaenoic acid (DHA)
which have amazing health benefits
Omega 3 plays a major role in a number of functions in our body. Here are they:-
Relaxation and contraction of muscles
Blood clotting
Digestion
Fertility
Cell division
Growth
Movement of calcium and other substances in and out of cells.
Omega -3 & omega -6 acids and their health effects.Zahir Khan
Omega-3 fatty acids are essential fatty acids, a class of nutrients needed for our body to function normally.
These are the fats of life which help our cells to function properly.
Omega-3 cannot be produced be our body and should be supplied through the diet
Omega-6 is essential to the body and the main omega-6 acid required by the body is Linoleic acid.
To know more email us : support@nirogam.com
Visit: www.nirogam.com
Nirogam India Pvt. Ltd.
F-32 & 33, 1st Floor
DLF Centre Point, Sector – 11,
Bata Mor, Main Mathura Road,
Faridabad, Haryana (India) - 121006
Mob: +91-9958171405 # 9015525552
Ph: 0129-4076777, 4006805
Facebook: www.facebook.com/nirogam
Web: www.nirogam.com
Email: info@nirogam.com
Omega 3,6 & 9 Fatty AcidsOmega-3 and omega-6 fatty acids are PUFAs and omega-9 fatty acids are usually MUFAs. The omega numbers simply reference how many carbons away from the methyl end of the fatty acid chain that the first carbon-carbon double bond appears. If the double bond is three carbons away, it's called an omega-3 fatty acid.,
Nutrition for glowing skin, healthy hair and nailsDt. Shagun Tomar
This presentation includes all the essential nutrients required for healthy skin, nails and hair. The foods to include and exclude for healthier body. Also examples of which food group to consume and what all food is included in that also with some recipes for glowing skin and healthier hair and nails.
Diet is not all about loosing or gaining weight, its therapeutic benefits are often taken lightly by most of us. Planning of a therapeutic diet implies the ability to adopt the principal of normal nutrition to the various regimens for adequacy, correctness, economy and palatability. It requires recognition of the need for dietary supplements such as vitamin and mineral concentrates when the nature of the diet itself imposes severe restrictions, the patient's appetite is poor or absorption and utilization are impaired so that the diet cannot meet the needs of optimum nutrition.
There are several therapeutic benefits of a well balanced diet such as:
•Fuel to perform daily activities
•Nutrients for the body's cells
•Growth and repair of tissue
•Reinforcing the immune system
•Preventing chronic diseases of lifestyle
•Maintaining good mental health
•Ensuring healthy teeth and bones
Omega 3 fatty acids are the most important and least understood nutrition among people. Here we try to show you a glimpse of what it is.....Read more on our blog....
http://curegoutpainnow.com
The best long term results are obtained by eating a properly planned uric acid diet. Any diet plan that is prescribed for gout patients must be able to reduce the level of uric acid in the blood.
Stress and Nutrition "Diet for Stress Management"Fatima Kader
A crisp yet informative presentation on the importance of nutritional therapy for all those facing chronic stress. Stress being inevitable these days due to our existing lifestyle, ways to combat it becomes even more essential. For further details on diet for various disease conditions Contact: Clinical Nutritionist, Ms Fatima Kader (Urjaa Homeopathic Centre) www.urjaa.in
Omega−3 fatty acids, also called Omega-3
oils, ω−3 fatty acids or n−3 fatty acids,
are polyunsaturated fatty acids (PUFAs)
characterized by the presence of a double
bond three atoms away from the terminal
methyl group in their chemical structure.
They are widely distributed in nature, being
important constituents of animal lipid
metabolism, and they play an important
role in the human diet and in human
physiology.
https://www.slideshare.net/DauRamChandravanshi1
Impressive health benefits of pumpkin seeds A series of PresentationByMr...Mr.Allah Dad Khan
A series of PresentationByMr. Allah Dad Khan former DG Agriculture Extension KP Province and Visiting Professor the University of Agriculture Peshawar allahdad52@gmail.com
Role of Essential Fatty Acids by Sayali ParabSayali Parab
Role of Essential Fatty Acids. “Essential Fatty Acid" refers to fatty acids required for biological processes but does not include the fats that only act as fuel.
Omega-6 is essential to the body and the main omega-6 acid required by the body is Linoleic acid.
To know more email us : support@nirogam.com
Visit: www.nirogam.com
Nirogam India Pvt. Ltd.
F-32 & 33, 1st Floor
DLF Centre Point, Sector – 11,
Bata Mor, Main Mathura Road,
Faridabad, Haryana (India) - 121006
Mob: +91-9958171405 # 9015525552
Ph: 0129-4076777, 4006805
Facebook: www.facebook.com/nirogam
Web: www.nirogam.com
Email: info@nirogam.com
Omega 3,6 & 9 Fatty AcidsOmega-3 and omega-6 fatty acids are PUFAs and omega-9 fatty acids are usually MUFAs. The omega numbers simply reference how many carbons away from the methyl end of the fatty acid chain that the first carbon-carbon double bond appears. If the double bond is three carbons away, it's called an omega-3 fatty acid.,
Nutrition for glowing skin, healthy hair and nailsDt. Shagun Tomar
This presentation includes all the essential nutrients required for healthy skin, nails and hair. The foods to include and exclude for healthier body. Also examples of which food group to consume and what all food is included in that also with some recipes for glowing skin and healthier hair and nails.
Diet is not all about loosing or gaining weight, its therapeutic benefits are often taken lightly by most of us. Planning of a therapeutic diet implies the ability to adopt the principal of normal nutrition to the various regimens for adequacy, correctness, economy and palatability. It requires recognition of the need for dietary supplements such as vitamin and mineral concentrates when the nature of the diet itself imposes severe restrictions, the patient's appetite is poor or absorption and utilization are impaired so that the diet cannot meet the needs of optimum nutrition.
There are several therapeutic benefits of a well balanced diet such as:
•Fuel to perform daily activities
•Nutrients for the body's cells
•Growth and repair of tissue
•Reinforcing the immune system
•Preventing chronic diseases of lifestyle
•Maintaining good mental health
•Ensuring healthy teeth and bones
Omega 3 fatty acids are the most important and least understood nutrition among people. Here we try to show you a glimpse of what it is.....Read more on our blog....
http://curegoutpainnow.com
The best long term results are obtained by eating a properly planned uric acid diet. Any diet plan that is prescribed for gout patients must be able to reduce the level of uric acid in the blood.
Stress and Nutrition "Diet for Stress Management"Fatima Kader
A crisp yet informative presentation on the importance of nutritional therapy for all those facing chronic stress. Stress being inevitable these days due to our existing lifestyle, ways to combat it becomes even more essential. For further details on diet for various disease conditions Contact: Clinical Nutritionist, Ms Fatima Kader (Urjaa Homeopathic Centre) www.urjaa.in
Omega−3 fatty acids, also called Omega-3
oils, ω−3 fatty acids or n−3 fatty acids,
are polyunsaturated fatty acids (PUFAs)
characterized by the presence of a double
bond three atoms away from the terminal
methyl group in their chemical structure.
They are widely distributed in nature, being
important constituents of animal lipid
metabolism, and they play an important
role in the human diet and in human
physiology.
https://www.slideshare.net/DauRamChandravanshi1
Impressive health benefits of pumpkin seeds A series of PresentationByMr...Mr.Allah Dad Khan
A series of PresentationByMr. Allah Dad Khan former DG Agriculture Extension KP Province and Visiting Professor the University of Agriculture Peshawar allahdad52@gmail.com
Role of Essential Fatty Acids by Sayali ParabSayali Parab
Role of Essential Fatty Acids. “Essential Fatty Acid" refers to fatty acids required for biological processes but does not include the fats that only act as fuel.
Flaxseeds are the richest source of α-linolenic acid and lignans. It is also a considerable potential source of soluble fiber, antioxidants and high quality protein. The role of flaxseed lignans and ω-3 fatty acid in reducing the risks associated with cardiac and coronary disease, cancer (breast, colon, ovary and prostate) and other human health risk factors has been well known.
Omega-3 fatty acids are essential polyunsaturated fats found in fish, flaxseeds, and walnuts. They support heart health by reducing inflammation and improving cholesterol levels. Additionally, they promote brain function and development, potentially reducing depression and anxiety. These vital nutrients are crucial for overall well-being and must be obtained through diet.
IC Fitness Club, an institute of Fitness Science, founded by Deepak Bhardwaj with the aim to provide best educational and knowledgeable fitness courses to the gym trainers. Deepak Bhardwaj, The Principal, has been teaching the students since 2016 and founded IC Fitness Club ® - Best Personal Trainer Course in Delhi and Sports Nutrition Course in Delhi
Address: B-5, 1st floor, above Fed Bank, Dwarka Mor, Patel Garden, New Delhi, Delhi 110078
Phone: 088514 19719
The term essential fatty acids (EFA) refers to those polyunsaturated fatty acids (PUFA) that must be provided by foods because these cannot be synthesized in the body yet are necessary for health
Nutrilite by Amway. This presentation details about the sources, process and benefits of Nutrilite range of Supplements.
The Nutrilite Health Institute provides a comprehensive Principles of Nutrition course that covers the fundamentals of nutrition science. The course is designed to help individuals understand the importance of proper nutrition for overall health and wellness. The course material includes detailed PowerPoint presentations, audio and video resources, and interactive quizzes to enhance learning. To download the course materials, visit the Nutrilite Health Institute website and register for the course.
Nutrilite supplements have gained popularity and are considered to be of good quality. Nutrilite is a well-known brand that specializes in dietary supplements and multivitamins. Their products are sold globally and are backed by the Nutrilite Health Institute, which focuses on research and development in the field of nutrition.
It's important to note that the efficacy of any supplement depends on individual needs, health conditions, and lifestyle factors. Before incorporating any supplement into your routine, it is recommended to consult with a healthcare professional to ensure it aligns with your specific needs and goals.
If you're interested in learning more about the Nutrilite range of products and their benefits, I recommend visiting the Nutrilite Health Institute website. They provide detailed information about their products and offer resources to help individuals make informed decisions about their nutrition and wellness.
For information on Herbalife products or for help with your Nutrition please contact me on:
email: healthyestelle@gmail.com
skype: starestelle59
1. The macro and micro nutrients the body requires
2. The main functions of each nutrient
3. The best food sources for each nutrient
4. The five different food groups
5. The main nutrients of each of the food groups
6. Recommended daily servings
7. The main nutrients you receive from fruit and vegetables
8. Why these nutrients are so important for you
9. Four key nutrients, vitamin C, vitamin A and potassium
How you identify the fatty types you eatAhmed Wahdan
We all have our eating habits, some more or less good for our health. On fatty acids (lipids, fats), be aware that they are not equivalent. Some are in favor, others limit. If you identify those you consume regularly, you can then make a few adjustments to your highest good!
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
2. Content:
• Introduction
• Type
• Function of omega 3 and omega 6
• Sources of omega-3 and omega-6.
• Deficiency and disease of omega-3 and omega-6
• Health benefits
• Applications
2
3. Omega 3 Fatty Acid
Omega 3 fatty acids are essential fatty acids , a class of
nutrients needed for our body to functional normally.
These are the fats of life which help our cells to
function properly. Omega 3 can’t be produced be our
body and should be supplied through the diet.
3
5. ALPHA LINOLEIC ACID
Alpha-linolenic acid is an n-3 fatty acid. It is one of two essential
fatty acids, so called because they are necessary for health and can’t
be produced within the human body.
5
7. Docosahexaenoic Acid
Docosahexaenoic acid is an omega-3 fatty acid that is a primary
structural component of the human brain, cerebral cortex, skin,
sperm, testicles, and retina.
7
8. Function of omega-3 fatty Acids
Omega 3 plays a major role in a number of functions in our body. Here
are they:
• Relaxation and contraction of muscles
• Blood clotting
• Digestion
• Fertility
• Cell division
• Growth
• Movement of calcium and other substances in and out of the cells.
8
9. Source of omega-3
Fish and fish oil: sardines, salmon ,tuna, trout, cod.
Nuts and seeds: walnuts, flaxseed.
Veggies: spinach, cauliflower, Brussels, sprouts.
Oil: flaxseed oil, soybean oil.
Beans: kidney beans, pinto and mungo beans
Eggs.
9
10. Omega-3 Deficiency
1.rough or dry, bumpy skin
2.dry,dull brittle hair and dandruff
3.soft peeling or brittle nails
4. Excessive thirst
5. Difficulty sleeping.
10
13. Neuropsychiatric Disorders
Decreased blood levels of omega-3 fatty acids have be associated
with several neuropsychiatric conditions including attention deficit
(hyperactive)disorder, Alzheimer’s disease, schizophrenia and
depression.
13
14. Health Benefits
Reduce cardiovascular risk factors
Reduces morning stiffness, swollen joints and rheumatoid
arthritis.
Lower the risk of cancer
Reduces inflammation throughout the body
Reduces the risk of obesity
Maintains fluidity of cell membrane.
14
15. Omega-6 fatty Acids
A class of essential fatty acids found in fish oil, especially from
salmon and other cold water fish, that acts to lower the levels of
cholesterol and LDL in the blood. LDL is the “bad" cholesterol.
15
16. Function of Omega-6 fatty Acids
Omega-6 is essential to the body and the main omega 6 is
required by the body is linolenic acid.
Along with omega-3, omega-6 acids also play a crucial role in
brain function, normal growth and development.
It also helps to stimulate skin, enhance hair growth, maintain
bone health, regulate metabolism and maintain health
reproductive system.
16
17. Source of omega-6 fatty acids
• It is primarily found in vegetable oil, which are very much
abundant in all processed foods.
• Meat and dairy
• Grains and cereals
17
18. Omega-6 deficiency
Eczema or dry ,irritated skin
Water loss
Hair loss
Drying eyes
Arthritis
High cholesterol
Kidney damage
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20. Health benefits
Omega-6 suppresses the immune system leaving the body more
susceptible to disease.
Decease formation of blood clots.
Promotes increase in cellular growth, reduce to cancer.
It also decrease to arthritis, mood disorders, osteoporosis and
obesity.
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21. Applications
The fatty acids in omega-3 and omega-6 series have been integrated to
feed, food and nutraceutical products.
Oils derived from microorganisms, called single cell oils(SCO) are
sustainable alternatives for the nutritionally important fatty acids.
Dietary supplements are the largest segment in the application of omega-
3 PUFA but are slow growing.
The pharmaceutical category is set to witness significant growth as a
result of consumers opting for higher concentrated omega-3 PUFA
products and purchasing omega-3 PUFA products prescribed by doctor.
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