The document summarizes new features in version 1.35 of software for the SOCT Copernicus optical coherence tomography device. Key updates include an optical nerve head analysis module, improvements to the user interface to make examinations more ergonomic, automated image analysis capabilities, and various retina measurement tools. The software will be available for existing devices starting in late April 2007 following final testing and an upgrade preparation period.

1. SOCT Copernicus Training OPTOPOL Technology Sp. z o.o. ul. Żabia 42 42-400 Zawiercie www.optopol.com Paweł Wojdas [email_address] New features – New software pre market presentation

2. Presentation Part I Version 1.35 – description of new features Part II Market situation and competitors

3. Terminology: A-scan, B-scan, 3D-scan 3D- scan A-scan B-scan

8. Results review Tomogram window

9. Results review Automated Image analysis Normal retina Pathology (Drusen)

11. Results review Retina analysis window

13. Results review Retina measurements IS/OS to RPE thickness

14. Results review Nerve head analysis module

15. Results review Nerve head analysis module Fundus reconstruction image Disc marker(blue) cup marker (green) Retina cross section image Disc marker (blue) Cup marker (green) RNFL thickness map

16. Results review Nerve head analysis module Cup offset slider Disc and Cup parameters panel RNFL thickness graph around disc

19. How to find disc and cup position Nerve head analysis module Cup local width Disc local width

20. Disc and cup parameters Nerve head analysis module Disc area – measured along green line plane Cup area – measured along white line plane Rim area=Disc area – Cup area Advantages of this method: measured values are independend of tilt of scans

21. Disc and cup parameters Nerve head analysis module Cup volume measured for all scans from white line

22. Disc and cup parameters Nerve head analysis module Rim volume measured for all scans above white line

23. Disc and cup parameters Nerve head analysis module Cup depth

27. Cup to disk ratio Nerve head analysis module Normal Glaucoma

28. Cup to disk ratio Nerve head analysis module Glaucoma Normal

29. Editing recognized points Nerve head analysis module It is possible to reposition recognized points by dragging them using mouse - at cross section image Use handles to drag

30. Editing recognized points Nerve head analysis module It is possible to reposition automaticaly recognized points by dragging them using mouse - in cross section image Use handles to drag

32. RNFL thickness analysis Nerve head analysis module Use this handle to adjust radius - Parameters of analysed area can be edited manually Use this handle to adjust ring thickness

36. Power supply connection PC LCD PRN SEPARATING TRANSFORMER MEDICAL DEVICES NON MEDICAL DEVICES Low leakage current requirement for medical systems

38. End of part 1 Thank you