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MUTATIONS
Changes in the gene
http://www.youtube.com/watch?v=5raJePXu0
OQ&feature=related SNPs and Mutation
Why is a change in the
code (mutation)
important for survival?
Give an example.
While the copying of DNA is a
very accurate process, what
happens when a letter is
altered?
VC: DNA Mutation
Given the code of a DNA molecule,
what would be the code of the new
DNA strand?
1 T A C CGGA T GC C AGA T C AAA T C
2 A T GGC C T A CGG T C T AG T T T AG
1 T A C CGGA T GC C AGA T C AAA T C
2
B. What happened in the DNA code?
1 T A C CGGA T GC C AGA T C AAA T C
2 A T GGC C T A CGG T C T AG T T T AG
2 A T CGC C T A CGG T C T AG T T T AG
A. Normal DNA Code
C. What is the NEW DNA code?
3 A T CGC C T A CGG T C T AG T T T AG
POINT MUTATION
B. What happened in the DNA code?
1 T A C CGGA T GC C AGA T C AAA T C
2 A T GGC C T A CGG T C T AG T T T AG
2 A T GC C T A CGG T C T AG T T T AG
A. Normal DNA Code
C. What is the NEW DNA code?
3 A T GCC T A CGG T C T AG T T T AG
FRAME SHIFT MUTATION
B. What happened in the DNA code?
1 T A C CGGA T GC C AGA T C AAA T C
2 A T GGC C T A CGG T C T AG T T T AG
2 A T GGC C T A CGG T C T AG T T T AG
A. Normal DNA Code
C. What is the NEW DNA code?
3 ATGTGC C TACGGT C TAGT T TAG
FRAME SHIFT MUTATION
T
2. CODE IS READ.
1 T A C CGGA T GC C AGA T C AAA T C
2 A T GGC C T A CGG T C T AG T T T AG
3 A T CGC C T A CGG T C T AG T T T AG
4 UAGCGGAUGC CAGAUCAAAUC
5 UAG CGG AUG CCA GAU CAA AUC
6 Stop Arg Meth Prol Aspa Glut Isol
U A C Correct code: Tyrosine
Notes on Mutation

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Notes on Mutation

  • 3. Why is a change in the code (mutation) important for survival? Give an example.
  • 4. While the copying of DNA is a very accurate process, what happens when a letter is altered? VC: DNA Mutation
  • 5. Given the code of a DNA molecule, what would be the code of the new DNA strand? 1 T A C CGGA T GC C AGA T C AAA T C 2 A T GGC C T A CGG T C T AG T T T AG 1 T A C CGGA T GC C AGA T C AAA T C 2
  • 6. B. What happened in the DNA code? 1 T A C CGGA T GC C AGA T C AAA T C 2 A T GGC C T A CGG T C T AG T T T AG 2 A T CGC C T A CGG T C T AG T T T AG A. Normal DNA Code C. What is the NEW DNA code? 3 A T CGC C T A CGG T C T AG T T T AG POINT MUTATION
  • 7. B. What happened in the DNA code? 1 T A C CGGA T GC C AGA T C AAA T C 2 A T GGC C T A CGG T C T AG T T T AG 2 A T GC C T A CGG T C T AG T T T AG A. Normal DNA Code C. What is the NEW DNA code? 3 A T GCC T A CGG T C T AG T T T AG FRAME SHIFT MUTATION
  • 8. B. What happened in the DNA code? 1 T A C CGGA T GC C AGA T C AAA T C 2 A T GGC C T A CGG T C T AG T T T AG 2 A T GGC C T A CGG T C T AG T T T AG A. Normal DNA Code C. What is the NEW DNA code? 3 ATGTGC C TACGGT C TAGT T TAG FRAME SHIFT MUTATION T
  • 9. 2. CODE IS READ. 1 T A C CGGA T GC C AGA T C AAA T C 2 A T GGC C T A CGG T C T AG T T T AG 3 A T CGC C T A CGG T C T AG T T T AG 4 UAGCGGAUGC CAGAUCAAAUC 5 UAG CGG AUG CCA GAU CAA AUC 6 Stop Arg Meth Prol Aspa Glut Isol U A C Correct code: Tyrosine