Non-sampling error can occur during various stages of a study including population specification, coverage, selection, data collection, and analysis. Population specification bias occurs when the target population is poorly defined. Coverage bias results from a mismatch between the sampling frame and target population. Selection bias arises from systematic differences between selected and non-selected study elements. Non-response bias is due to differences between participants and non-participants. Response and data processing/analysis biases stem from invalid or inappropriate data. Minimizing these biases requires clearly defining populations, comprehensive training, quality control procedures, and error detection methods.