Learn the symptoms of Gastroesophageal Reflux Disease (GERD) and Barrett’s esophagus, and when they may warrant further medical attention. Hear the latest in treatment methods, including radio frequency ablation and endoscopic ultrasound.
GERD | Gastro esophageal reflux disease-a brief medical study martinshaji
Gastro esophageal reflux disease (GERD) is a chronic digestive disease. GERD occurs when stomach acid or, occasionally, stomach content, flows back into your food pipe (esophagus). The backwash (reflux) irritates the lining of your esophagus and causes GERD. This is a very common condition observed
please comment
thank you
Ulcers are the areas of degeneration and necrosis of gastro intestinal mucosa exposed to acid of the alimentary tract that is exposed to hydrochloric acid and pepsin they occur most commonly (98-99%) in either the duodenum or the stomach in the ratio 4:1
GERD | Gastro esophageal reflux disease-a brief medical study martinshaji
Gastro esophageal reflux disease (GERD) is a chronic digestive disease. GERD occurs when stomach acid or, occasionally, stomach content, flows back into your food pipe (esophagus). The backwash (reflux) irritates the lining of your esophagus and causes GERD. This is a very common condition observed
please comment
thank you
Ulcers are the areas of degeneration and necrosis of gastro intestinal mucosa exposed to acid of the alimentary tract that is exposed to hydrochloric acid and pepsin they occur most commonly (98-99%) in either the duodenum or the stomach in the ratio 4:1
Servikal İntraepitelyal Neoplazilerde (CIN) Yönetim nasıl olmalıdır?
HPV virüsü tipi takipte önemli midir? CIN1, CIN2 ve CIN3 te tedavi yöntemi ne olmalıdır?
This presentation summarizes the state of the art with respect to the management of GIST. It covers the basics of surgical and medical management including the role of neoadjuvant and adjuvant targeted therapy. www.ellenhornmd.com
GERD is most common gastric problem in community affecting large number of people. Diagnosis and management is very simple with understanding.
http://www.youtube.com/c/DrDhavalMangukiyaGastrosurgeonSurat
https://gastrosurgerysurat.blogspot.com/
https://drdhavalmangukiya.com/
Gastroesophageal Reflux Disease (GERD) is a common disorder that has undergone many paradigm changes in the last 15 years. We discuss the current paradigms in the pathophysiology, diagnosis and management of GERD.
GERD (Gastro Esophageal Reflux Disease) is one of the commonest medical conditions found in the community today. GERD patients often suffer from frequent symptoms and require long term medication. However, how much of what we know about GERD is truly fact based on medical evidence? We challenge traditional paradigms to GERD
What may have seemed like science fiction, surgery without an incision, is now a reality that is making lives better for patients suffering from chronic acid reflux also known as gastroesophageal reflux disease (GERD). Peter Janu, MD, a general surgeon, provides basic information about GERD as well as common treatment options including the new TIF (transoral incisionless fundoplication) procedure for the treatment of GERD.
GERD (gastroesophageal reflux disease, or chronic acid reflux) is a condition in which acid-containing contents in your stomach persistently leak back up into your esophagus, the tube from your throat to your stomach.
Although GERD itself isn't a life threatening condition, it can lead to more serious health issues and complications if it's left untreated.
Its an overview about Gastro-Esophageal Reflux Disease, mainly focused on Clinical features, Role of Investigation, Diagnostic Criteria, Management plan.
It was mainly prepared for a scientific seminer. It may help others as well.
Pediatric Talk: Managing Arthritis During the Holidays - Dr. Marla Guzman - ...Summit Health
While holiday celebrations and activities are great fun, it’s also a disruptor to the daily routine. Our expert will share tips to help you navigate holiday season stressors to minimize your child’s risk of a potential flare-up. This virtual event is hosted by the Arthritis Foundation.
Safety and Success in a Post-Pandemic Society - Daniela Accurso, MD, MPH - 7...Summit Health
The Covid-19 Pandemic has been a health crises that we have been fighting for the last year and a half. Dr. Accurso’s presentation is focused on reviewing how far we have come as a society and to address the questions, health concerns, and important precautions we need to take as we integrate ourselves back into a healthy community.
Melanoma: Prevention, Detection and Treatment - Stephanie Badalamenti, MD - L...Summit Health
Sun safety needs to start at an early age, and continue throughout life, in order to reduce the risk for skin cancer. Learn about prevention and ways to reduce your risk, screening for skin cancer and innovations in treatments.
Melanoma: Prevention, Detection and Treatment - Stephanie Badalamenti, MD - L...Summit Health
Sun safety needs to start at an early age, and continue throughout life, in order to reduce the risk for skin cancer. Learn about prevention and ways to reduce your risk, screening for skin cancer and innovations in treatments.
Shoulder Pain Relief: Common Rotator Cuff Injuries & Treatment Options - And...Summit Health
If you are experiencing shoulder pain, a rotator cuff tear could be the issue. Learn about how, and why, rotator cuff tears happen, how the condition and severity is diagnosed, and the non-surgical and surgical treatment options available.
My Knee Hurts! A Look at Joint Pain in Children - Marla Guzman, MD - 1.12.2021Summit Health
Is your child complaining of joint pain? Learn about concerning symptoms and when to seek medical advice. Our expert discusses the various causes of joint pains in children, how a pediatric rheumatologist evaluates musculoskeletal complaints, and available treatment options.
Mildred “Mitch” Bentler, MA, RD, CSP, CDE, presented a virtual lecture at on diabetes prevention. According to Ms. Bentler,
“A combination of small changes can really make an impact on lowering your blood sugar. Increasing physical activity and adopting healthier eating habits can go a long way to reducing your diabetes risk.”
Why Does My Stomach Ache? - Dennis Han, MD, Gastroenterologist - Morristown &...Summit Health
Do you have stomach issues which are bothering you and you can't figure out why? Learn about conditions that could be causing abdominal pain or discomfort at this virtual program. Our expert will discuss different conditions such as: Irritable Bowel Syndrome; Inflammatory Bowel Disease; Celiac Disease and other conditions that require a gluten-free diet; and GERD (Reflux). He will explain the differences between these various conditions, how they are diagnosed, and treatment options available. Hosted by Morristown & Morris Township Public Library.
Know Your Numbers and What They Mean for Your Overall Health - Madison Public...Summit Health
What does your blood pressure, BMI, cholesterol, blood sugar and vitamin levels tell you about your health? Our expert will discuss how these numbers tell a story, and why it’s important to understand what that story means to your overall health. Dr. Im-Imamura will also share tips for helping you get these numbers where they should be, and how increasing physical activity and improving nutrition are key factors that can impact those numbers in a good way.
Presented as part of the Madison Public Library Virtual Seminar Series.
Understanding Knee Arthritis and Cartilage Disorders - Maurice M. Pine Free P...Summit Health
Many people suffer from pain, swelling, stiffness, and loss of knee function as a result of knee arthritis. Our expert will discuss the causes, symptoms, and nonsurgical and surgical treatment options available. Hosted by Maurice M. Pine Free Public Library.
Pulmonologist, Jenny Kim, MD, FCCP of our Sleep Disorders Center partnered with the Livingston Health Department to present, Can’t Sleep? The ABCs of Your ZZZs to the community. During the session, Dr. Kim discussed tips for improving sleep and treatment options for common sleep disorders.
Christina Lavner, RDN, Nutrition Services, presented Healthy Eating for Cancer Survivorship, as the second session of our Now What? A Cancer Survivorship Speaker Series for patients wanting to learn more about nutrition that will benefit them during and after treatment. Be sure to check out upcoming presenters in this series and pass the word on to any patients you think would be interested in the information. The next presentation in this series is November 16, Coping with Treatment Side Effects, presented by Constance Gore, RN-APN
Guide to Eating an Anti-Inflammatory Diet Virtual Lecture - Christina Lavner,...Summit Health
An anti-inflammatory diet, along with exercise, can yield many health benefits, such as improved symptoms of many chronic conditions, reduced cancer risk, and a lower risk of obesity, heart disease, and diabetes. Learn more about this healthy way of eating and how to get started.
While most common in teens, the onset of acne can be troubling at any age. Depending on its severity, acne can cause emotional distress and scar the skin. The earlier you start treatment, the lower your risk of such problems. Learn about the causes of acne and effective treatment options for adolescents and adults.
Living a Heart Healthy Life - Liliana Cohen - West Orange Public Library - 2....Summit Health
Learn how to make healthy choices that impact heart health, the typical mistakes to avoid, and how to recognize the signs and symptoms of a heart attack.
Heart of the Matter - Ali Ahmad, MD, FACC - Livingston Library - 1.6.2020Summit Health
Heart disease is the leading killer of adults nationwide and it carries a significant morbidity for the population at risk. Learn about traditional and non-traditional risk factors associated with coronary artery disease, and how to modify your risk and prevent heart disease. Also, learn about how heart disease affects different ethnic backgrounds, particularly the high-risk groups, such as South Asians.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
2. GERD Overview
• Reflux occurs when the stomach contents reflux or
back up into the esophagus and/or mouth.
Reflux is a normal process that occurs in healthy individuals
Most episodes are brief and do not cause symptoms or
complications
Mostly after meals, rarely at night
Results from transient relaxation of the muscle sphincter in
lower esophagus
• People with GERD experience symptoms or
complications as a result of the reflux
3.
4. GERD is a Common Problem
80 Males
Females
60
Prevalence (%)
Any episode
of GERD symptoms
40
At least weekly
20 episodes of GERD
symptoms
0
25–34 35–44 45–54 55–64 65–74
Age (years) Locke et al. Gastroenterology 1997
5. Symptoms of GERD
• Typical symptoms
Pain in the upper abdomen
Burning chest pain
Food getting stuck (dysphagia)
Pain upon swallowing (odynophagia)
Taste of acid or food in throat or food or fluid coming up
without effort (regurgitation)
• Atypical symptoms
Persistent sore throat
Sense of a lump in the throat
Waking up with a choking sensation
6. Symptoms of GERD
• Atypical symptoms continue
Persistent laryngitis/hoarseness
Chronic cough, new onset asthma, or asthma only at night
Worsening dental disease
Recurrent Pneumonia
Chronic sinusitis
7. Natural History of GERD
• Majority of patients do very well and only require
symptom control
• Minority will develop serious complications
8. Potential Complications of
GERD
• Severe esophageal inflammation and esophageal
ulcer formation
• Esophageal stricture formation (narrowing diameter)
• Barrett’s esophagus
• Esophageal cancer
• Hoarseness
• Pneumonia which if frequent may lead to permanent
lung damage
9. Barrett’s Esophagus
• Changing in the lining of the esophagus to become
intestine like lining
• Exact number of effected individual is unknown
Overall 1.6%
• 1.4% no GERD symptoms
• 2.3% with GERD symptoms
Risks factors
• Male
• Caucasian
• Smoking
• Hiatal hernia
• Increased visceral fat deposition
Ronkainen J, et al. Prevalence of Barrett's esophagus in the general population: an endoscopic study. Gastroenterology.
2005;129:1825-31.
Bonino JA. Barret’s esophagus. Current opinion in gastroenterology 2006,22:406-411
10. Barrett’s Esophagus and
Esophageal Cancer
• The exact increase risk is unclear
Increased risk by 30-125 folds
• Esophageal cancer is uncommon
Life time risk of developing esophageal cancer 0.4-0.5 per
100 patients per year
• 1% per year in LGD
• 10% per year in HGD
• Risk to progress to HGD is 0.9 per year
• Likely progression from Barrett’s LGD HGD
Ad Ca
~18% in LGD
~ 34% HGD
11. Surveillance for Barrett’s
Esophagus
• Not clear if useful but usually recommended
• At first endoscopy perform extensive biopsy
No dysplasia, confirmed by second endoscopy within 1 year
→ EGD in 3-5 years
LGD EGD in 1 year vs. treatment
HGD In individual with reasonable life
expectancy consider treatment
12. Treatment of Barrett’s
Esophagus
• Control acid and inflammation usually by medication
• Eradication of Barrett’ tissue by heat or cold or other
methods
• Removal of early cancer endoscopically
• For advanced cancer either surgery or chemotherapy
and radiation therapy
13. HALO Device (Barrx Device)
• A device delivers heat to get rid of Barrett’s tissue
• Usually recommended for patients with dysplasia and
few selected patients without dysplasia
About 90% chance of eliminating dysplasia and
Barrett’s esophagus and at least tow fold decrease
in cancer risk
Durable at 5 years but no longer term data
14. When Do I Need to Seek
Medical Care?
• Symptoms are getting worse or inability to control
them
• When you are in doubt if something wrong
• Need to seek immediate medical care
•
Trouble swallowing/chocking or sensation of food being
stuck or lump in throat
•
Unintentional weight loss
Chest pain
Vomiting blood or having bowel movements that are black or
look like tar
15. Diagnosing GERD
• Clinical by history and therapeutic trial
• Endoscopy
• PH testing
• Esophageal manometry
• Radiology
16. Treatment of GERD
• Life style modification
• Medications
• Endoscopic procedure
• Surgery
17. Life Style modification
Not clear if it is effective but usually recommended
• Lose weight (if you are overweight)
• Raise the head of your bed by 6 to 8 inches
• Avoid foods that make your symptoms worse
• Coffee, chocolate, alcohol, peppermint, and fatty foods
• Cut down on the amount of alcohol you drink
• Stop smoking
• Frequent small meal, avoid overeating
• Eat a bunch of small meals each day
• Avoid lying down for 3 hours after a meal
20. Medications
• Antacids work for mild infrequent episodes of GERD
or as adjuvant to other medication in more severe
case
• Antihistamine work in mild GERD and not very
effective to heal severe esophageal inflammation
21. Medications
• PPI as class are the strongest medication
Heal inflammation over 80%
Most work better if taken before meals
Usually once a day and occasionally twice a day
For symptoms control only initial treatment is 8 weeks
• If symptoms relapse within 3 months usually are needed for long term
Goal of therapy is to use the lowest effective dose of
medication
Usually safe but can lead to decrease bone dentistry and
nutrient absorption and increase risk of infections especially
clostridium difficile
22. My Medications Are Not Working
What Should I Do ?
• If PPI, are you taking it before meal?
• Change to different PPI
• PPI twice a day
• Additional testing
• Consideration for surgery
23. Surgery for GERD
• Goal to increase barrier to acid reflux with minimal impact on the
ability to swallow
• Surgery plays an important role in patients with large hiatus
hernia and those unable or unwilling to take long term
medications
• Majority are done laparoscopically, result depends on surgeon
experience
• Potential complications
Difficulty swallowing (5%)
Sense of bloating and gas
Breakdown of the repair (1 to 2 percent of patients per year)
Diarrhea due to inadvertent injury to the nerves
24.
25. Summary
• GERD is common and in a majority of
cases has benign course
• Use lowest effective dose of medication
• Trouble swallowing, chest pain or
bleeding seek immediate attention
• Barrett’s esophagus in a majority of
cases does not lead to cancer, but
keeping an eye on it is advisable
26. For more information
Call (908) 273.4300
Visit: summitmedicalgroup.com
Connect with us on
Facebook/SummitMedicalNJ
Twitter: @SummitMedicalNJ
Editor's Notes
Prevalence western country 10-20%, less in Asia, 7% of population may need long tern medication Mild one episode per week Severe >3 per week