The document discusses a new hypothesis testing method that addresses challenges in hypothesis testing, particularly the absence of control groups and small sample sizes. It proposes using regression analysis to measure the effect size of treatments applied in a single store, incorporating factors such as trend, seasonality, and macroeconomic variables. Additionally, it highlights the advantages of this method, including generating p-values and confidence intervals, while also addressing issues related to autocorrelation and heteroskedasticity in regression analysis.