Nevoid Hyperkeratosis Of The Nipple And Areola
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A 10-year-old female patient presented with a pigmented lesion on her right nipple that had appeared 3 months prior. Examination of the lesion revealed it was not clearly defined and had a slight papillomatous surface. No other lesions were seen on the areola. Differential diagnoses included nevoid hyperkeratosis of the nipple and areola or a melanocytic lesion. A biopsy was proposed but the parents did not consent. Dermoscopy may be useful in aiding diagnosis in this case.
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A 50-year-old woman was referred to a dermatologist for assessment of a lesion on her nose that had been present for 1 year. A biopsy confirmed it was a superficial basal cell carcinoma. She was treated with imiquimod 5% cream applied 5 times per week, which caused mild side effects after 2 weeks but cleared the lesion completely after 4 weeks of treatment.
Imiquimod
A 50-year-old woman was referred to a dermatology department for assessment of a lesion on her nose that had been present for 1 year. A biopsy confirmed it was a superficial basal cell carcinoma. She was treated with imiquimod 5% cream applied 5 times per week for 6 weeks. After 2 weeks of treatment, she developed mild erythema, crusting, and burning sensation at the site.
Pinkus
A 47-year-old man was referred for assessment of two lesions on his right gluteal and lower back that had been present for 3 years. The lesion was excised and histopathological examination revealed features consistent with fibroepithelioma of Pinkus (FEP). FEP is an uncommon variant of basal cell carcinoma first described by Hermann Pinkus in 1953. It presents as a single or multiple dome-shaped papules or large pedunculated tumors that can be pink, yellow, brown, or skin colored. Treatment options for FEP are similar to those for basal cell carcinoma.
Keratoacanthoma. spontaneous regresion
A 70-year-old woman was referred to a dermatologist for evaluation of a lesion on her forehead that had developed over the previous 4 weeks. A biopsy confirmed it was a keratoacanthoma. The patient did not attend her scheduled surgical treatment. When she returned 3 months later, the lesion had completely regressed, leaving only a scar. Keratoacanthomas are rapidly growing skin tumors that may occur as single or multiple lesions. They typically stop growing after 6-8 weeks, remain unchanged for 2-6 more weeks, then slowly regress over 2-12 months, often healing with scarring.
Keratoacanthoma. spontaneous regresion
A 70-year-old woman was referred to a dermatologist for evaluation of a lesion on her forehead that had developed over the previous 4 weeks. A biopsy confirmed it was a keratoacanthoma. The patient did not attend her scheduled surgical treatment. When she returned 3 months later, the lesion had completely regressed, leaving only a scar. Keratoacanthomas are rapidly growing skin tumors that may occur as single or multiple lesions. They typically stop growing after 6-8 weeks, remain unchanged for 2-6 more weeks, then slowly regress over 2-12 months, often healing with scarring.
Granuloma piogeno vih
A 45-year-old HIV-positive man presented with a lesion on his finger that had grown over the past 3 months. Upon excision and histological examination, the tumor was found to be a pyogenic granuloma, an overgrowth of blood vessels typically seen in HIV patients.
Granuloma piogeno vih
A 45-year-old HIV-positive man presented with a lesion on his finger that had grown over the past 3 months. Upon excision and histological examination, the tumor was found to be a pyogenic granuloma, an overgrowth of blood vessels typically seen in HIV patients.
Lichen planus afroamerican people
Lichen planus is a pruritic, papular skin condition characterized by violaceous polygonal papules and plaques that commonly appear on the wrists, genitals, and mucous membranes. While lichen planus does not typically have a racial predilection, one study found higher rates among African American children. In patients with dark skin like African Americans, the lesions will not appear violaceous but rather be pigmented, though they can still have a shiny appearance when light reflects off of them. The document then describes a case report of a 30-year-old African American female patient referred for assessment of pigmented lesions on her skin that had appeared over the prior 4 months.
Lichen planus afroamerican people
Lichen planus is a pruritic, papular skin condition characterized by violaceous polygonal papules and plaques that typically appear on the wrists, genitals, and mucous membranes. While lichen planus does not generally have a racial predilection, one study found a higher prevalence among African American children. In patients with dark skin, the lesions will not appear violaceous but rather be pigmented; however, they will still have the characteristic polygonal, flat-topped papules that shine when light reflects off of them. The document then describes a case report of a 30-year-old African American woman who presented with pigmented lichen planus lesions on her skin
Adalimumab in combination with methotrexate
This case report describes a 54-year old woman with severe plaque psoriasis who did not respond to various treatments including PUVA, cyclosporine, and methotrexate. She was started on adalimumab with an initial dose of 80 mg followed by 40 mg one week later and 40 mg every other week, which resulted in an improvement in her psoriasis. However, she did not have a complete response, so methotrexate 5 mg weekly was added to her treatment regimen. The combination of adalimumab and methotrexate proved to be safe and effective for her, with her psoriasis well controlled on this combination therapy.
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