This document discusses neural tissue mobilization of the upper limb. It defines neurodynamics as the clinical application of nervous system mechanics and physiology as they relate to musculoskeletal function. Neurodynamic tests are described to assess the median, ulnar, and radial nerves. The tests involve moving the associated joints in specific positions and directions to apply tension or sliding movement to the nerves while monitoring for symptoms. Structural differentiation is used to identify the level of nerve involvement. Contraindications for neural tissue mobilization include certain nervous system disorders or areas of instability. The goal is to assess nerve mobility and produce tension or gliding of the nerves for non-irritable neurogenic or neuropathic conditions.