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Anatomy and Physiology I
The Nervous System
Basic Structure and Function
Instructor: Mary Holman
Three Basic Functions of the
Nervous System
Sensory Function
Sensory or afferent neurons
Integrative Function
Interneurons
Motor Function
Motor or efferent neurons
Fig. 10.2a
Brain
Spinal
cord Spinal nerves (31 pairs)
Cranial nerves (12 pairs)
CNS vs PNS
Central Nervous System Peripheral Nervous System
Divisions of the Nervous System
Central Nervous System CNS
Brain
Spinal Cord
Peripheral Nervous System PNS
Cranial Nerves
Spinal Nerves
Ganglia
Sensory Receptors
Divisions of the PNS
Somatic Nervous System
Sensory neurons
Motor neurons to skeletal muscle only
Autonomic Nervous System
Autonomic sensory neurons - visceral
Motor neuron impulses to smooth & cardiac muscle,
glands and adipose tissue
Sympathetic vs. Parasympathetic Motor Divisions
Enteric Nervous System
Enteric complexes of the gut
Fig. 10.7
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Central nervous system Peripheral nervous system
Cell body
Interneurons
Dendrites
Axon
Axon
Sensory (afferent) neuron
Motor (efferent) neuron
Cell body
Axon
(central process)
Axon
(peripheral process)
Sensory
receptor
Effector
(muscle or gland)
Axon
terminal
Cells of Neural Tissue
• Neurons
The electrically excitable nerve cells
responsible for the functions of the
nervous system
• Neuroglia (glia, neuroglia, glial)
Support, nourish, & protect neurons
Fig. 10.1
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Dendrites
Cell body
Axon
Nuclei of
neuroglia
© Ed Reschke
The Neuron
600x
Fig. 10.3
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Cell body
Neurofibrils
Nucleus
Nucleolus
Dendrites
Impulse
Nodes of Ranvier
Myelin (cut)
Axon
Axon
Chromatophilic
substance
(Nissl bodies)
Axonal
hillock
Portion of a
collateral
Schwann
cell
Nucleus of
Schwann cell
Synaptic knob of
axon terminal
Neuron with
Myelinated
Axon
Fig. 10.6
Dendrites
Axon Axon
Axon
Direction
of impulse
(a) Multipolar
Central
process
Peripheral
process
(c) Unipolar
(b) Bipolar
(eyes,nose,ears)
Neuroglia of the PNS
• Schwann Cells
Produce myelin sheath
• Satellite Cells
Support neuronal clusters in
ganglia
Fig. 10.4a
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Dendrite
Node of Ranvier
Myelinated region of axon
Axon
Unmyelinated
region of axon
Neuron
cell body
Neuron
nucleus
Medullated or Myelinated Axon
Schwann cells
Neurolemma
containing nucleus
Fig. 10.4b
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Neurilemma
Myelin sheath
Neurofibrils
Axon
Axon
Node of Ranvier
Myelin
Schwann cell
nucleus
© Biophoto Associates/Photo Researchers, Inc.
650x
Schwann Cell
Fig. 10.4c
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Enveloping
Schwann cell
Schwann
cell nucleus
Unmyelinated
axon
Longitudinal
groove
Schwann Cell with non-myelinated Axons
Fig. 10.5
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Schwann
cell cytoplasm
Myelin
sheath
Myelinated
axon
Unmyelinated
axon
© Dennis Emery
30,000x
Neuroglia of the CNS
• Astrocytes
major support cells
provide nutrients, monitor metabolism etc
• Oligodendrocytes
myelinate axons in CNS
• Microglia
phagocytic
• Ependymal
line ventricles & central canal
produce cerebrospinal fluid (CSF)
Fig. 10.8
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Microglial cell
Axon
Oligodendrocyte
Astrocyte
Capillary
Neuron
Myelin
sheath (cut)
Node of
Ranvier
Ependymal
cell
Fluid-filled cavity
of the brain or
spinal cord
Neuroglia of CNS
Fig. 10.9
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Neuroglia
Neuron
cell body
Tissues and Organs: A Text-Atlas of Scanning Electron Microscopy, by R.G. Kessel and R.H. Kardon. ©1979 W.H. Freeman and Company
SEM 10,000x
Fig. 10.10
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Axon
Site of injury Schwann cells
(a)
(b)
(c)
(d)
(e)
Changes over
time
Motor neuron
cell body
Former connection
reestablished
Schwann cells
Form new myelin sheath
Schwann cell tube
extends distal to injury
Proximal end of injured axon
regenerates into tube of Schwann cells
Distal portion of
axon degenerates
Skeletal
muscle fiber
Axonal Repair

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Nervous System Structure and Function.ppt

  • 1. Anatomy and Physiology I The Nervous System Basic Structure and Function Instructor: Mary Holman
  • 2. Three Basic Functions of the Nervous System Sensory Function Sensory or afferent neurons Integrative Function Interneurons Motor Function Motor or efferent neurons
  • 3. Fig. 10.2a Brain Spinal cord Spinal nerves (31 pairs) Cranial nerves (12 pairs) CNS vs PNS Central Nervous System Peripheral Nervous System
  • 4. Divisions of the Nervous System Central Nervous System CNS Brain Spinal Cord Peripheral Nervous System PNS Cranial Nerves Spinal Nerves Ganglia Sensory Receptors
  • 5. Divisions of the PNS Somatic Nervous System Sensory neurons Motor neurons to skeletal muscle only Autonomic Nervous System Autonomic sensory neurons - visceral Motor neuron impulses to smooth & cardiac muscle, glands and adipose tissue Sympathetic vs. Parasympathetic Motor Divisions Enteric Nervous System Enteric complexes of the gut
  • 6. Fig. 10.7 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Central nervous system Peripheral nervous system Cell body Interneurons Dendrites Axon Axon Sensory (afferent) neuron Motor (efferent) neuron Cell body Axon (central process) Axon (peripheral process) Sensory receptor Effector (muscle or gland) Axon terminal
  • 7. Cells of Neural Tissue • Neurons The electrically excitable nerve cells responsible for the functions of the nervous system • Neuroglia (glia, neuroglia, glial) Support, nourish, & protect neurons
  • 8. Fig. 10.1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Dendrites Cell body Axon Nuclei of neuroglia © Ed Reschke The Neuron 600x
  • 9. Fig. 10.3 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Cell body Neurofibrils Nucleus Nucleolus Dendrites Impulse Nodes of Ranvier Myelin (cut) Axon Axon Chromatophilic substance (Nissl bodies) Axonal hillock Portion of a collateral Schwann cell Nucleus of Schwann cell Synaptic knob of axon terminal Neuron with Myelinated Axon
  • 10. Fig. 10.6 Dendrites Axon Axon Axon Direction of impulse (a) Multipolar Central process Peripheral process (c) Unipolar (b) Bipolar (eyes,nose,ears)
  • 11. Neuroglia of the PNS • Schwann Cells Produce myelin sheath • Satellite Cells Support neuronal clusters in ganglia
  • 12. Fig. 10.4a Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Dendrite Node of Ranvier Myelinated region of axon Axon Unmyelinated region of axon Neuron cell body Neuron nucleus Medullated or Myelinated Axon Schwann cells Neurolemma containing nucleus
  • 13. Fig. 10.4b Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Neurilemma Myelin sheath Neurofibrils Axon Axon Node of Ranvier Myelin Schwann cell nucleus © Biophoto Associates/Photo Researchers, Inc. 650x Schwann Cell
  • 14. Fig. 10.4c Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Enveloping Schwann cell Schwann cell nucleus Unmyelinated axon Longitudinal groove Schwann Cell with non-myelinated Axons
  • 15. Fig. 10.5 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Schwann cell cytoplasm Myelin sheath Myelinated axon Unmyelinated axon © Dennis Emery 30,000x
  • 16. Neuroglia of the CNS • Astrocytes major support cells provide nutrients, monitor metabolism etc • Oligodendrocytes myelinate axons in CNS • Microglia phagocytic • Ependymal line ventricles & central canal produce cerebrospinal fluid (CSF)
  • 17. Fig. 10.8 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Microglial cell Axon Oligodendrocyte Astrocyte Capillary Neuron Myelin sheath (cut) Node of Ranvier Ependymal cell Fluid-filled cavity of the brain or spinal cord Neuroglia of CNS
  • 18. Fig. 10.9 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Neuroglia Neuron cell body Tissues and Organs: A Text-Atlas of Scanning Electron Microscopy, by R.G. Kessel and R.H. Kardon. ©1979 W.H. Freeman and Company SEM 10,000x
  • 19. Fig. 10.10 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Axon Site of injury Schwann cells (a) (b) (c) (d) (e) Changes over time Motor neuron cell body Former connection reestablished Schwann cells Form new myelin sheath Schwann cell tube extends distal to injury Proximal end of injured axon regenerates into tube of Schwann cells Distal portion of axon degenerates Skeletal muscle fiber Axonal Repair