The nervous system controls and coordinates all essential functions of the human body. It has three main functions: sensory, which uses receptors to monitor changes inside and outside the body; integrative, which processes sensory input and makes decisions; and motor, which sends instructions to muscles, glands and organs to respond. The brain and spinal cord act as command centers, receiving sensory information and issuing instructions. The brain is located in the skull and controls thoughts and emotions, while the spinal cord is the reflex and conduction pathway in the vertebrae.