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Necrotizing enterocolitis HY
- 1. Necrotizing enterocolitis
Pathogenesis
• Gut mucosal wall invasion by gas-producing bacteria
• Intestinal inflammation, necrosis
Risk
factors
• Prematurity
• Very low birth weight (<1.5 kg [3.3 lb])
• Enteral feeding
Clinical
findings
• Nonspecific: apnea, lethargy, vital sign instability
• Gastrointestinal
• Abdominal distension
• Feeding intolerance, bilious emesis
• Bloody stools
X-ray
findings
• Pneumatosis intestinalis (air in bowel wall)
• Pneumoperitoneum (free air under diaphragm)
Complications
• Sepsis, disseminated intravascular coagulation
• Late: strictures, short-bowel syndrome
![Necrotizing enterocolitis
Pathogenesis
• Gut mucosal wall invasion by gas-producing bacteria
• Intestinal inflammation, necrosis
Risk
factors
• Prematurity
• Very low birth weight (<1.5 kg [3.3 lb])
• Enteral feeding
Clinical
findings
• Nonspecific: apnea, lethargy, vital sign instability
• Gastrointestinal
• Abdominal distension
• Feeding intolerance, bilious emesis
• Bloody stools
X-ray
findings
• Pneumatosis intestinalis (air in bowel wall)
• Pneumoperitoneum (free air under diaphragm)
Complications
• Sepsis, disseminated intravascular coagulation
• Late: strictures, short-bowel syndrome](https://image.slidesharecdn.com/necrotizingenterocolitis-210609125856/85/Necrotizing-enterocolitis-HY-1-320.jpg)
