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Systemic lupus erythematosus
Clinical
presentation
• Gradual symptom onset
• Malar or discoid rash
• Joint, renal, serosal &/or neurologic
involvement
Laboratory
abnormalities
• Anemia, leukopenia, thrombocytopenia
• Positive ANA, anti–double-stranded DNA,
anti-Smith
• Low complement levels, increased immune
complexes

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Systemic lupus erythematosus HY

  • 1. Systemic lupus erythematosus Clinical presentation • Gradual symptom onset • Malar or discoid rash • Joint, renal, serosal &/or neurologic involvement Laboratory abnormalities • Anemia, leukopenia, thrombocytopenia • Positive ANA, anti–double-stranded DNA, anti-Smith • Low complement levels, increased immune complexes