Richard Feynman is credited with the birth of nanotechnology in 1959 when he challenged scientists that manipulating matter at the nanoscale was possible if the laws of physics allowed. Nanobiotechnology was initiated in 1980 with the development of atomic force microscopy that enables atomic-level imaging. Nanobiotechnology involves creating functional materials and devices through understanding and controlling matter at the nanometer scale of 1 to 100 nm, where new properties emerge. Applications include biomedical imaging, advanced drug delivery, biosensing, and regenerative medicine.
The document describes a nanoparticle-based method for detecting enzyme activity using quantum dots. Specifically:
- Enzymes catalyze chemical reactions in the body, and abnormal enzyme activity can indicate disease. The method allows simple detection of enzyme activity.
- It uses quantum dots that fluoresce at one wavelength. When an enzyme modifies a substrate linked to the dots, a dye molecule emits at a different wavelength via FRET.
- By measuring the ratio of dye to dot fluorescence, the assay can quantify enzyme activity levels down to subnanomolar concentrations, comparable to current methods. It has potential applications in disease screening, drug development, and detecting other chemical changes.
Protein based nanostructures for biomedical applications karoline Enoch
Proteins are kind of natural molecules that show unique
functionalities and properties in biological materials and
manufacturing feld. Tere are numerous nanomaterials
which are derived from protein, albumin, and gelatin. Tese
nanoparticles have promising properties like biodegradability, nonantigenicity, metabolizable, surface modifer, greater
stability during in vivo during storage, and being relatively
easy to prepare and monitor the size of the particles.
These particles have the ability to attach covalently with
drug and ligand
This document discusses viral nanoparticles and their applications. It begins with an introduction to viruses and their structure. Viruses can be engineered as nanomachines through genetic engineering, bioconjugation, biomineralization, and encapsulation. Viral nanoparticles have applications in targeted drug delivery, vaccines, imaging, and plant disease management. Challenges include issues with purity, scaling up production, and structural complexity. Overall, viral nanoparticles show promise as biological nanocarriers for applications in biomedicine and agriculture due to their ability to be chemically and genetically modified to carry drugs, toxins, and targeting sequences.
DNA Nanotechnology: Concept and its Applications
DNA Nanotechnology # Various 2 and 3 dimensional shapes of DNA nanotechnology # DNA Origami # with their application and Future scope
This document discusses nanomedicine and its potential applications. Nanomedicine uses engineered nanodevices and nanostructures to monitor, repair, construct and control human biological systems at the molecular level. The goals of nanomedicine include improved diagnostics, treatment and prevention through a personalized single platform that integrates detection, diagnostics, treatment. Some potential applications discussed include using nanoparticles to deliver drugs precisely to tumor sites, detecting cancer at the molecular level, and developing multifunctional therapeutics. While nanomedicine is not fully realized yet, it could change medicine by making therapies more effective, economical and safe compared to current methods.
This document provides an introduction to nanobiotechnology, including its concepts, scope, applications, and future prospects. It defines nanobiotechnology as the combination of nanotechnology and biotechnology, manipulating matter at the nanoscale (1-100 nm) for biological applications. Examples of current applications include growing whole organs like bladders using stem cells, developing targeted cancer drug delivery, and creating polymers to detect metabolites. The future scope may include using molecular manufacturing to program nanobots for delicate surgeries and environmental repair like reconstructing the ozone layer. Overall, the document outlines how nanobiotechnology interfaces biology and nanoscale engineering.
Richard Feynman is credited with the birth of nanotechnology in 1959 when he challenged scientists that manipulating matter at the nanoscale was possible if the laws of physics allowed. Nanobiotechnology was initiated in 1980 with the development of atomic force microscopy that enables atomic-level imaging. Nanobiotechnology involves creating functional materials and devices through understanding and controlling matter at the nanometer scale of 1 to 100 nm, where new properties emerge. Applications include biomedical imaging, advanced drug delivery, biosensing, and regenerative medicine.
The document describes a nanoparticle-based method for detecting enzyme activity using quantum dots. Specifically:
- Enzymes catalyze chemical reactions in the body, and abnormal enzyme activity can indicate disease. The method allows simple detection of enzyme activity.
- It uses quantum dots that fluoresce at one wavelength. When an enzyme modifies a substrate linked to the dots, a dye molecule emits at a different wavelength via FRET.
- By measuring the ratio of dye to dot fluorescence, the assay can quantify enzyme activity levels down to subnanomolar concentrations, comparable to current methods. It has potential applications in disease screening, drug development, and detecting other chemical changes.
Protein based nanostructures for biomedical applications karoline Enoch
Proteins are kind of natural molecules that show unique
functionalities and properties in biological materials and
manufacturing feld. Tere are numerous nanomaterials
which are derived from protein, albumin, and gelatin. Tese
nanoparticles have promising properties like biodegradability, nonantigenicity, metabolizable, surface modifer, greater
stability during in vivo during storage, and being relatively
easy to prepare and monitor the size of the particles.
These particles have the ability to attach covalently with
drug and ligand
This document discusses viral nanoparticles and their applications. It begins with an introduction to viruses and their structure. Viruses can be engineered as nanomachines through genetic engineering, bioconjugation, biomineralization, and encapsulation. Viral nanoparticles have applications in targeted drug delivery, vaccines, imaging, and plant disease management. Challenges include issues with purity, scaling up production, and structural complexity. Overall, viral nanoparticles show promise as biological nanocarriers for applications in biomedicine and agriculture due to their ability to be chemically and genetically modified to carry drugs, toxins, and targeting sequences.
DNA Nanotechnology: Concept and its Applications
DNA Nanotechnology # Various 2 and 3 dimensional shapes of DNA nanotechnology # DNA Origami # with their application and Future scope
This document discusses nanomedicine and its potential applications. Nanomedicine uses engineered nanodevices and nanostructures to monitor, repair, construct and control human biological systems at the molecular level. The goals of nanomedicine include improved diagnostics, treatment and prevention through a personalized single platform that integrates detection, diagnostics, treatment. Some potential applications discussed include using nanoparticles to deliver drugs precisely to tumor sites, detecting cancer at the molecular level, and developing multifunctional therapeutics. While nanomedicine is not fully realized yet, it could change medicine by making therapies more effective, economical and safe compared to current methods.
This document provides an introduction to nanobiotechnology, including its concepts, scope, applications, and future prospects. It defines nanobiotechnology as the combination of nanotechnology and biotechnology, manipulating matter at the nanoscale (1-100 nm) for biological applications. Examples of current applications include growing whole organs like bladders using stem cells, developing targeted cancer drug delivery, and creating polymers to detect metabolites. The future scope may include using molecular manufacturing to program nanobots for delicate surgeries and environmental repair like reconstructing the ozone layer. Overall, the document outlines how nanobiotechnology interfaces biology and nanoscale engineering.
introduction to Nanobiotechnology
what is nanotechnology
bionanotechnology
classical biotechnology industrial production using biological system
modern biotechnology from industrial processes to noval therapeutics
modern biotechnology immunological enzymatic and neucleic acid based technology
Dna based technology
self assembly and supramolecular chemistry
formation of ordered structure at nano scale
This document discusses cytotoxicity and methods for measuring it in vitro. It defines cytotoxicity as the ability of chemicals or cells to destroy living cells, which can lead to necrosis, apoptosis, or cytostasis. Measuring cytotoxicity is important for drug development and safety testing. In vitro assays are now commonly used as they are faster, cheaper, and more accurate than animal models. Several types of cytotoxicity assays are described, including dye exclusion assays like trypan blue, colorimetric assays like MTT, fluorometric assays like CFDA-AM, and luminometric assays like ATP assays. These assays measure endpoints such as membrane integrity, enzyme activity, proliferation, and ATP production to determine cytotoxic effects of chemicals on cells.
This document discusses the use of nanoparticles in drug delivery systems. Nanoparticles can be used to more precisely control the release of drugs in the body over time compared to traditional drug dosing. Magnetic nanoparticles are particularly useful as they can be guided to specific target sites in the body using external magnetic fields. The document outlines various methods for synthesizing magnetic nanoparticles and functionalizing them for drug delivery applications. Characterization techniques are also discussed for analyzing the nanoparticles. The document concludes that magnetic nanoparticles have the potential to improve drug targeting and control drug release while maintaining low toxicity.
Use of Nanotechnology in Diagnosis and Treatment of CancerAnas Indabawa
The document discusses how nanotechnology can be used for cancer diagnosis and treatment. It describes several nanoscale devices such as nanopores, nanotubes, quantum dots, dendrimers, liposomes, nanoshells, and nanorobots that can help detect genetic mutations associated with cancer, target delivery of drugs to cancer cells, and enable non-invasive cancer diagnosis and treatment with localized heat therapy. The manipulation of matter at the nanoscale allows more precise cancer detection and targeted therapy with fewer side effects than traditional approaches.
Nanotechnology offers promising applications in diagnostic pathology through the use of nanoscale devices and materials. Some key applications discussed in the document include using cantilevers to detect cancer biomarkers, nanopores for efficient DNA sequencing, nanotubes to map DNA mutations, nanoshells that absorb light for cancer treatment, dendrimers for drug delivery, magnetic nanoparticles as MRI contrast agents, quantum dots as fluorescent probes, and graphene oxide sheets for attaching antibodies for medical diagnosis. Overall, nanotechnology enables detection, imaging, and analysis at the molecular level for early disease diagnosis and targeted treatment.
This document discusses cell culture based vaccine production. It begins by introducing different types of vaccines and traditional egg-based vaccine production methods and their limitations. It then describes the importance and advantages of cell culture based methods, including types of cells used. The key steps of the cell culture based production process are outlined, including strain selection, bulk production, purification, virus inactivation, formulation, quality control testing, and lot release. Specific cell culture based vaccines for influenza, rabies, dengue, and Ebola are discussed. The conclusion emphasizes the potential for cell culture to replace egg-based methods by producing vaccines faster and in larger quantities to meet global demand.
This document discusses nanotechnology and its applications in medicine. It begins with the origins and definitions of nanotechnology. Some key approaches to nanofabrication include top-down and bottom-up methods. Nanocarriers such as liposomes, dendrimers, micelles, and nanoparticles can be used for targeted drug delivery. Nanotechnology has applications in regenerative medicine, disease diagnosis using nanomolecular diagnostics, and in-vitro diagnostics including nano biosensors and nanoarrays. Overall, nanomedicine holds promise for earlier disease detection and more targeted treatment approaches.
NANO TECHNOLOGY IN DRUG DELIVERY SYSTEMsathish sak
This document discusses how nanoparticles can be used for targeted drug delivery in cancer and inflammation. Nanoparticles less than 100nm in size can be engineered from biodegradable materials to efficiently carry drugs and be taken up by targeted cells. They allow for higher doses of drugs to be delivered directly to diseased cells over prolonged periods of time, reducing side effects. Examples discussed include using nanoparticles to target cancer cells, tumor angiogenesis, infected macrophages, and inflammatory molecules. The future potential of nanotechnology for improved targeted drug delivery is promising.
Natural Biological assembly at nanoscale slidesnida fatima
The document discusses natural biological assembly at the nanoscale. It covers self-assembly of DNA and proteins. DNA can self-assemble into nanostructures through techniques like DNA origami which uses a long viral DNA folded with short staple strands. Proteins self-assemble through folding and interacting subunits. Examples given are ferritin protein cages and peptide nanofibers. Applications of biological nanostructures include drug delivery, sensors, information storage and pollution detection.
The document discusses various applications of nanotechnology in biomedical fields such as medicine and healthcare. It describes how nanotechnology can be used to develop targeted drug delivery systems, lab-on-chip devices for disease detection and diagnosis, bionanomaterials for medical applications, and nanoscale machines and sensors. It also discusses how nanotechnology enables more precise detection and treatment of diseases like cancer at the molecular level with fewer side effects.
Applications of nanobiotechnology in medicineRameshPandi4
Nanomedicine uses nanotechnology to detect and treat diseases at the molecular level. Applications include using nanoparticles for targeted drug delivery to cancer sites, using nanobots to identify and destroy cancer cells, using photodynamic therapy to destroy tumors by activating nanoparticles with light, and developing nanorobots to remove plaque from arteries or break up kidney stones. Future applications may involve cell-sized robots to detect diseases by floating through the bloodstream or developing respirocytes as artificial red blood cells to deliver oxygen throughout the body.
Nanotechnology & nanobiotechnology by kk sahuKAUSHAL SAHU
Introduction &definition
a) Nanotechnology
b) Nanobiotechnology
History
Terms related to Nanotechnology
Nanoscale technology
Some Nanoscale related terms
What are Nanosensors
How nanosensors work
DNA Nanotechnology
How Nanotechnology works in different fields
Advantages & application of Nanotechnology
Disadvantages
Conclusion
References
Introduction
Definition
History
Advantages of nanobiotechnology
Applications of nanobiotechnology
Drawback of nanobiotechnology
New features in the nanobiotechnology
Conclusion
References
Nanotechnology involves manipulating matter at the nanoscale, between 1 to 100 nanometers. Nanobiotechnology applies nanotechnology to biological systems. It develops tools to study biological phenomena at the nanoscale. Some key applications of nanotechnology and nanoparticles include medicine for targeted drug delivery, electronics for smaller devices, energy like solar cells, and environmental areas like water filtration. Nanoparticles are synthesized using various methods and have properties dependent on their size. While nanotechnology provides advantages like improved materials and devices, concerns also exist around health and environmental effects of nanoparticles.
Application of Biological Assemblies in NanoBiotechnology PPtZohaib HUSSAIN
The document discusses several applications of biological assemblies in nanobiotechnology. It describes how biological assemblies, such as hemoglobin, are the functional forms of molecules and can be used to build larger structures. It then discusses using drug nanocrystals to improve drug solubility and bioavailability. Next, it covers using nano-containers like liposomes for targeted drug delivery. The document also discusses using protein crystals called S-layers for nanolithography and peptide templates for controlling biomineralization. Finally, it discusses the potential of utilizing biomineralization principles in nanotechnology applications like tissue engineering.
Applications of nanobiotechnology by kk sahuKAUSHAL SAHU
INTRODUCTION
DEFINITION
HISTORY
NANOSCALE
NANOPARTICLES
NANOBIOTECHNOLOGY
NANOTOOLS
APPLICATIONS
RESEARCH
CONCLUSION
REFRENCES
Nanotechnology is the design, characterization and application of structures, devices and systems by controlling shape and size at the nanometer scale!” defines the Royal Academy of Engineering in London in 2004 .
Concepts that are enhanced through nanobiology include: nanodevices, nanoparticles, and nanoscale phenomena that occurs within the discipline of nanotechnology.
This document discusses various nanotechnology approaches for drug delivery, including nanoparticles for encapsulating and delivering drugs. It describes several types of nanoparticles - lipid-based, polymer-based, metallic, biological - that can be used for targeted drug delivery. It also highlights some achievements of nanotechnology in developing improved drug formulations, as well as challenges in the field and priority research areas like cancer nanotechnology.
Introduction to Nanobiotechnology note.pdfyusufzako14
Nanobiotechnology combines nanotechnology and biotechnology to build and manipulate devices at the nanoscale for studying and engineering biological systems. It allows characterization of biological structures and functions at the nanoscale level. Key applications of nanobiotechnology include developing nanoprobes, nanoparticles, and nanodevices for applications in diagnostics, therapeutics, drug delivery, and tissue engineering in the fields of biology and medicine. Some examples discussed are using nanoparticles for imaging and drug delivery, developing nanosensors for cancer detection, and exploring the use of nanorobots for targeted drug delivery and tissue repair.
introduction to Nanobiotechnology
what is nanotechnology
bionanotechnology
classical biotechnology industrial production using biological system
modern biotechnology from industrial processes to noval therapeutics
modern biotechnology immunological enzymatic and neucleic acid based technology
Dna based technology
self assembly and supramolecular chemistry
formation of ordered structure at nano scale
This document discusses cytotoxicity and methods for measuring it in vitro. It defines cytotoxicity as the ability of chemicals or cells to destroy living cells, which can lead to necrosis, apoptosis, or cytostasis. Measuring cytotoxicity is important for drug development and safety testing. In vitro assays are now commonly used as they are faster, cheaper, and more accurate than animal models. Several types of cytotoxicity assays are described, including dye exclusion assays like trypan blue, colorimetric assays like MTT, fluorometric assays like CFDA-AM, and luminometric assays like ATP assays. These assays measure endpoints such as membrane integrity, enzyme activity, proliferation, and ATP production to determine cytotoxic effects of chemicals on cells.
This document discusses the use of nanoparticles in drug delivery systems. Nanoparticles can be used to more precisely control the release of drugs in the body over time compared to traditional drug dosing. Magnetic nanoparticles are particularly useful as they can be guided to specific target sites in the body using external magnetic fields. The document outlines various methods for synthesizing magnetic nanoparticles and functionalizing them for drug delivery applications. Characterization techniques are also discussed for analyzing the nanoparticles. The document concludes that magnetic nanoparticles have the potential to improve drug targeting and control drug release while maintaining low toxicity.
Use of Nanotechnology in Diagnosis and Treatment of CancerAnas Indabawa
The document discusses how nanotechnology can be used for cancer diagnosis and treatment. It describes several nanoscale devices such as nanopores, nanotubes, quantum dots, dendrimers, liposomes, nanoshells, and nanorobots that can help detect genetic mutations associated with cancer, target delivery of drugs to cancer cells, and enable non-invasive cancer diagnosis and treatment with localized heat therapy. The manipulation of matter at the nanoscale allows more precise cancer detection and targeted therapy with fewer side effects than traditional approaches.
Nanotechnology offers promising applications in diagnostic pathology through the use of nanoscale devices and materials. Some key applications discussed in the document include using cantilevers to detect cancer biomarkers, nanopores for efficient DNA sequencing, nanotubes to map DNA mutations, nanoshells that absorb light for cancer treatment, dendrimers for drug delivery, magnetic nanoparticles as MRI contrast agents, quantum dots as fluorescent probes, and graphene oxide sheets for attaching antibodies for medical diagnosis. Overall, nanotechnology enables detection, imaging, and analysis at the molecular level for early disease diagnosis and targeted treatment.
This document discusses cell culture based vaccine production. It begins by introducing different types of vaccines and traditional egg-based vaccine production methods and their limitations. It then describes the importance and advantages of cell culture based methods, including types of cells used. The key steps of the cell culture based production process are outlined, including strain selection, bulk production, purification, virus inactivation, formulation, quality control testing, and lot release. Specific cell culture based vaccines for influenza, rabies, dengue, and Ebola are discussed. The conclusion emphasizes the potential for cell culture to replace egg-based methods by producing vaccines faster and in larger quantities to meet global demand.
This document discusses nanotechnology and its applications in medicine. It begins with the origins and definitions of nanotechnology. Some key approaches to nanofabrication include top-down and bottom-up methods. Nanocarriers such as liposomes, dendrimers, micelles, and nanoparticles can be used for targeted drug delivery. Nanotechnology has applications in regenerative medicine, disease diagnosis using nanomolecular diagnostics, and in-vitro diagnostics including nano biosensors and nanoarrays. Overall, nanomedicine holds promise for earlier disease detection and more targeted treatment approaches.
NANO TECHNOLOGY IN DRUG DELIVERY SYSTEMsathish sak
This document discusses how nanoparticles can be used for targeted drug delivery in cancer and inflammation. Nanoparticles less than 100nm in size can be engineered from biodegradable materials to efficiently carry drugs and be taken up by targeted cells. They allow for higher doses of drugs to be delivered directly to diseased cells over prolonged periods of time, reducing side effects. Examples discussed include using nanoparticles to target cancer cells, tumor angiogenesis, infected macrophages, and inflammatory molecules. The future potential of nanotechnology for improved targeted drug delivery is promising.
Natural Biological assembly at nanoscale slidesnida fatima
The document discusses natural biological assembly at the nanoscale. It covers self-assembly of DNA and proteins. DNA can self-assemble into nanostructures through techniques like DNA origami which uses a long viral DNA folded with short staple strands. Proteins self-assemble through folding and interacting subunits. Examples given are ferritin protein cages and peptide nanofibers. Applications of biological nanostructures include drug delivery, sensors, information storage and pollution detection.
The document discusses various applications of nanotechnology in biomedical fields such as medicine and healthcare. It describes how nanotechnology can be used to develop targeted drug delivery systems, lab-on-chip devices for disease detection and diagnosis, bionanomaterials for medical applications, and nanoscale machines and sensors. It also discusses how nanotechnology enables more precise detection and treatment of diseases like cancer at the molecular level with fewer side effects.
Applications of nanobiotechnology in medicineRameshPandi4
Nanomedicine uses nanotechnology to detect and treat diseases at the molecular level. Applications include using nanoparticles for targeted drug delivery to cancer sites, using nanobots to identify and destroy cancer cells, using photodynamic therapy to destroy tumors by activating nanoparticles with light, and developing nanorobots to remove plaque from arteries or break up kidney stones. Future applications may involve cell-sized robots to detect diseases by floating through the bloodstream or developing respirocytes as artificial red blood cells to deliver oxygen throughout the body.
Nanotechnology & nanobiotechnology by kk sahuKAUSHAL SAHU
Introduction &definition
a) Nanotechnology
b) Nanobiotechnology
History
Terms related to Nanotechnology
Nanoscale technology
Some Nanoscale related terms
What are Nanosensors
How nanosensors work
DNA Nanotechnology
How Nanotechnology works in different fields
Advantages & application of Nanotechnology
Disadvantages
Conclusion
References
Introduction
Definition
History
Advantages of nanobiotechnology
Applications of nanobiotechnology
Drawback of nanobiotechnology
New features in the nanobiotechnology
Conclusion
References
Nanotechnology involves manipulating matter at the nanoscale, between 1 to 100 nanometers. Nanobiotechnology applies nanotechnology to biological systems. It develops tools to study biological phenomena at the nanoscale. Some key applications of nanotechnology and nanoparticles include medicine for targeted drug delivery, electronics for smaller devices, energy like solar cells, and environmental areas like water filtration. Nanoparticles are synthesized using various methods and have properties dependent on their size. While nanotechnology provides advantages like improved materials and devices, concerns also exist around health and environmental effects of nanoparticles.
Application of Biological Assemblies in NanoBiotechnology PPtZohaib HUSSAIN
The document discusses several applications of biological assemblies in nanobiotechnology. It describes how biological assemblies, such as hemoglobin, are the functional forms of molecules and can be used to build larger structures. It then discusses using drug nanocrystals to improve drug solubility and bioavailability. Next, it covers using nano-containers like liposomes for targeted drug delivery. The document also discusses using protein crystals called S-layers for nanolithography and peptide templates for controlling biomineralization. Finally, it discusses the potential of utilizing biomineralization principles in nanotechnology applications like tissue engineering.
Applications of nanobiotechnology by kk sahuKAUSHAL SAHU
INTRODUCTION
DEFINITION
HISTORY
NANOSCALE
NANOPARTICLES
NANOBIOTECHNOLOGY
NANOTOOLS
APPLICATIONS
RESEARCH
CONCLUSION
REFRENCES
Nanotechnology is the design, characterization and application of structures, devices and systems by controlling shape and size at the nanometer scale!” defines the Royal Academy of Engineering in London in 2004 .
Concepts that are enhanced through nanobiology include: nanodevices, nanoparticles, and nanoscale phenomena that occurs within the discipline of nanotechnology.
This document discusses various nanotechnology approaches for drug delivery, including nanoparticles for encapsulating and delivering drugs. It describes several types of nanoparticles - lipid-based, polymer-based, metallic, biological - that can be used for targeted drug delivery. It also highlights some achievements of nanotechnology in developing improved drug formulations, as well as challenges in the field and priority research areas like cancer nanotechnology.
Introduction to Nanobiotechnology note.pdfyusufzako14
Nanobiotechnology combines nanotechnology and biotechnology to build and manipulate devices at the nanoscale for studying and engineering biological systems. It allows characterization of biological structures and functions at the nanoscale level. Key applications of nanobiotechnology include developing nanoprobes, nanoparticles, and nanodevices for applications in diagnostics, therapeutics, drug delivery, and tissue engineering in the fields of biology and medicine. Some examples discussed are using nanoparticles for imaging and drug delivery, developing nanosensors for cancer detection, and exploring the use of nanorobots for targeted drug delivery and tissue repair.
This document discusses applications of nanotechnology in medicine. It describes how nanotechnology can be used for targeted drug delivery, cancer treatment through radio therapy, and biosensors. Targeted drug delivery uses nanoparticles to deliver drugs directly to diseased cells to minimize side effects. Radio therapy employs nanoparticles less than 50nm in size that can enter and exit cells to preferentially treat cancer. Biosensors combine biological components with detectors, and nanomaterials improve biosensor sensitivity for applications like food quality monitoring and medical diagnostics. While promising, nanomedicine also faces challenges like inconsistent nanoparticle effects that could become dangerous without further research.
This document discusses applications of nanotechnology in medicine. It describes how nanotechnology can be used for targeted drug delivery, cancer treatment through radio therapy, and biosensors. Targeted drug delivery uses nanoparticles to deliver drugs directly to diseased cells to minimize side effects. Radio therapy employs nanoparticles less than 50nm in size that can enter and exit cells to preferentially treat cancer. Biosensors combine biological components with detectors, and nanomaterials improve biosensor sensitivity for applications like food quality testing and medical diagnostics. While promising, nanomedicine also faces challenges like inconsistent nanoparticle effects that could become dangerous without further research.
role of nanotechonolgy in diagnostic pathology.pptxBVDUPathology1
Nanotechnology involves engineering materials and devices on the nanoscale (1-100 nm) and can be applied to diagnostic pathology. It allows for early disease detection by taking advantage of nanoparticles' high surface area and ability to interact with biomolecules. Common nanodiagnostic techniques include magnetic nanoparticles for MRI contrast, nanochips for DNA analysis, microfluidics to automate biochemical assays, and nanoarrays for high-throughput screening of proteins and nucleic acids. Future applications may integrate multiple functions like imaging, detection, targeted drug delivery, and treatment monitoring into single nanodevices.
This document discusses nanotechnology in medicine. It provides an introduction to nanotechnology and its history. It describes how nanotechnology is being used for targeted drug delivery, nasal vaccinations, carbon nanotubes, and potential future nano robots. Some applications of nanotechnology discussed are in diagnosis and treatment of diseases, nano biopharmaceutics, and overcoming challenges like crossing the blood brain barrier. Both advantages like better targeting and diagnostics and disadvantages like potential side effects are covered. Future challenges for nanomedicine are also outlined.
The document discusses the field of nanomedicine, which uses nanotechnology and medicine to develop novel therapies and improve existing treatments. It describes how atoms and molecules are manipulated at the nanoscale to interact with human cells. Examples of nanomedicine applications provided include quantum dots to detect and locate cancer cells, nanoparticles to deliver chemotherapy drugs directly to cancer cells, and nanotubes to identify DNA changes associated with cancer. The document outlines the advantages of nanomedicine in more precise targeting and delivery of drugs while reducing side effects, and the potential it holds to transform medicine.
Nanotechnology shows promise for medical diagnosis and treatment. It involves constructing and engineering functional systems at the atomic or nanoscale level, where unique properties emerge. Various nanodevices like quantum dots, magnetic nanoparticles, nanoshells, and dendrimers can be used for cancer detection, DNA sequencing, and drug delivery. Challenges include safety concerns over nanoparticle interactions and the need for multidisciplinary collaboration to advance applications. Overall, the integration of nanotechnology into healthcare has potential to transform disease diagnosis, monitoring, and therapy.
B.pharmacy notes of pharmaceutical nanotechnologyGulviShivaji
This document discusses trends in nanomaterials applications for bionanosensors and nanomedicine. It begins with definitions of key terms like nanotechnology, nanobiotechnology, and nanomedicine. It then discusses the state of the art in fields like nanomedicine, nanobiosensors, and nanomaterials. Specific topics covered include nanosensing devices, nanobiosensors, considerations of nanomaterial toxicology, and conclusions. Application domains for nanomedicine discussed include diagnostics, drug delivery, regenerative medicine, and cells therapy. The principles and components of nanobiosensors are also summarized, along with different sensing techniques like electrochemical, optical, and piezoelectric biosensors.
Nanoparticles between 1-100 nanometers in size are widely used in pharmaceutical analysis. They are used in (1) electrochemical analysis by constructing sensors and enhancing electron transfer, (2) clinical analysis by targeting biomarkers and improving detection sensitivity, and (3) separation analysis by acting as separation agents. Nanoparticles are also used to (4) enhance laser induced breakdown spectroscopy by lowering the breakdown threshold. They have various other applications including diagnostics, targeted drug delivery, and as biosensors and biolabels.
Clinical applications of bionanotechnologyHari kesavan
Bionanotechnology is a science that sits at the convergence of nanotechnology and biology. Nanobiology and nanobiotechnology are other names that are used interchangeably with bionanotechnology.
NANO BIOSENSORS AND INTERNET OF NANO THINGS (2022)anjana_rasheed
Nano biosensors and the Internet of Nano Things (IoNT) were discussed. Key points:
1. Nano biosensors use nanomaterials to improve sensitivity of traditional biosensors and can be portable, wearable or implantable.
2. IoNT is a collection of nano-scale sensor networks that transmit data through the cloud for remote monitoring applications.
3. Challenges for nano biosensors and IoNT include limited capabilities, compatibility issues, and health concerns about implanting electronic devices.
Nanorobots are tiny machines that could be used for medical applications in the future. They are approximately 10-9 meters in size. Nanorobots may have components like power sources, sensors, manipulators and payloads to carry drugs. They could be designed in different shapes and sizes to perform tasks like targeting and destroying cancer cells, breaking up blood clots or kidney stones, or precisely delivering drugs. While nanorobots show promise for rapid disease treatment, their design and safety would need to be carefully evaluated before human use due to regulatory challenges. Overall, nanorobots may revolutionize medicine if technical hurdles are overcome.
Principles of Nanobiotechnology. ppt.pptyusufzako14
Nanobiotechnology uses nanotechnology to analyze and engineer biological systems at the nanoscale level. The document provides an overview of key concepts in nanobiotechnology including:
- Nanoparticles which are between 1-100 nm and have unique physical and chemical properties compared to larger particles.
- Applications of nanotechnology in areas like medicine, where nanomedicine uses nanoparticles for imaging, drug delivery, and therapy. For example, iron oxide nanoparticles can improve MRI imaging of cancer tumors.
- Nanoparticles are also used for rapid medical diagnostics and early detection of diseases through sensors and probes. Gold nanoparticles attached to antibodies can provide quick flu virus diagnosis.
- Nanoparticles allow more targeted drug delivery
Nanosensor-basics, application and future.pptxdebeshidutta2
Nanosensors use components like an analyte, sensor, transducer and detector to detect changes in electrical signals or other physical properties when molecules interact with sensor materials like carbon nanotubes or graphene. They can function as chemical or mechanical sensors and are used in applications such as pollution monitoring, medical diagnosis, MEMS devices, and more. Future applications of nanosensors include rapid COVID-19 detection and continued development in clinical diagnostics and other fields.
Nano biotechnology, often referred to as nanobiotechnology, is a multidiscipl...ItsJimmy
It is a presentation related to nanobiotechnology which covered it's aspects including it's introduction, scope , uses , application and also includes nanofibers and nanotechnology.
Nanobiotechnology has many potential applications in areas like medicine, genomics, and robotics. It offers novel opportunities for molecular disease imaging, targeted drug delivery, and therapeutic intervention. Some key areas of focus are using nanoparticles for controlled drug release, protein-based drug delivery systems, magnetic nanoparticles for imaging and therapy, and gene delivery vectors like liposomes and dendrimers. Nanotechnology also has applications in cancer research, cardiovascular disorders, neuroscience, molecular diagnostics, and gene therapy. It provides tools for protein analysis, single-cell studies, and tissue engineering scaffolds. Overall, nanobiotechnology holds promise for advancing healthcare through applications in various areas of medicine and biotechnology.
A nanometer is a billionth of a meter
It's difficult to imagine anything so small, but think of
something only 1/80,000 the width of a human hair
Ten hydrogen atoms could be laid side-by- side in a single nanometer.
Nanotechnology is the creation of useful materials, devices, and systems through the manipulation of matter on this miniscule scale
There are many interesting nanodevices being developed that have a potential to improve cancer detection, diagnosis, and treatment
Nano electronics- role of nanosensors, pdf fileRishu Mishra
This document discusses nanosensors and their roles and applications in nanoelectronics. It describes how nanosensors can convey information about nanoparticles and have various medical and other uses. Some key applications of nanosensors discussed are in computers to make processors more powerful, in energy production to create more efficient solar cells, and in medical diagnostics to detect biomolecules in real time. Nanosensors are also discussed as having potential uses in chemical sensing by detecting various gas molecules and in detecting single molecules using nano-cantilevers. The document outlines several approaches for producing nanosensors, including top-down lithography, bottom-up assembly of individual atoms/molecules, and self-assembly of starter molecules.
A Review Paper on Latest Biomedical Applications using Nano-Technologyijsrd.com
At present, Nano technology has been improved in many ways but it had improved a lot in the case of Nano Medicine.It also plays a major role in engineering basis. The application of nano technology in medicine is called as Nano medicine. This paper explains the detail regarding Nano medicine. Nano technology has many molecular properties and applications of biological nano structure. These have physical, chemical and biological properties. These are mainly used to diagonize diseases from our body. Nano technology has special application in Nano medicine using Nano robot. This paper relates the use of Nano robots in surgeries. thes Nano robots are not oly safebut also faster. The size of these nano robot is 1-100nm.These use to cure many problems.
EWOCS-I: The catalog of X-ray sources in Westerlund 1 from the Extended Weste...Sérgio Sacani
Context. With a mass exceeding several 104 M⊙ and a rich and dense population of massive stars, supermassive young star clusters
represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions
among stars.
Aims. In this paper we present the Extended Westerlund 1 and 2 Open Clusters Survey (EWOCS) project, which aims to investigate
the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars.
The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.
Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically,
the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec.
Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within
and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation
were carried out using the ACIS-Extract software.
Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a
photon flux threshold of approximately 2 × 10−8 photons cm−2
s
−1
. The X-ray sources exhibit a highly concentrated spatial distribution,
with 1075 sources located within the central 1 arcmin. We have successfully detected X-ray emissions from 126 out of the 166 known
massive stars of the cluster, and we have collected over 71 000 photons from the magnetar CXO J164710.20-455217.
Or: Beyond linear.
Abstract: Equivariant neural networks are neural networks that incorporate symmetries. The nonlinear activation functions in these networks result in interesting nonlinear equivariant maps between simple representations, and motivate the key player of this talk: piecewise linear representation theory.
Disclaimer: No one is perfect, so please mind that there might be mistakes and typos.
dtubbenhauer@gmail.com
Corrected slides: dtubbenhauer.com/talks.html
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills MN
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptxMAGOTI ERNEST
Although Artemia has been known to man for centuries, its use as a food for the culture of larval organisms apparently began only in the 1930s, when several investigators found that it made an excellent food for newly hatched fish larvae (Litvinenko et al., 2023). As aquaculture developed in the 1960s and ‘70s, the use of Artemia also became more widespread, due both to its convenience and to its nutritional value for larval organisms (Arenas-Pardo et al., 2024). The fact that Artemia dormant cysts can be stored for long periods in cans, and then used as an off-the-shelf food requiring only 24 h of incubation makes them the most convenient, least labor-intensive, live food available for aquaculture (Sorgeloos & Roubach, 2021). The nutritional value of Artemia, especially for marine organisms, is not constant, but varies both geographically and temporally. During the last decade, however, both the causes of Artemia nutritional variability and methods to improve poorquality Artemia have been identified (Loufi et al., 2024).
Brine shrimp (Artemia spp.) are used in marine aquaculture worldwide. Annually, more than 2,000 metric tons of dry cysts are used for cultivation of fish, crustacean, and shellfish larva. Brine shrimp are important to aquaculture because newly hatched brine shrimp nauplii (larvae) provide a food source for many fish fry (Mozanzadeh et al., 2021). Culture and harvesting of brine shrimp eggs represents another aspect of the aquaculture industry. Nauplii and metanauplii of Artemia, commonly known as brine shrimp, play a crucial role in aquaculture due to their nutritional value and suitability as live feed for many aquatic species, particularly in larval stages (Sorgeloos & Roubach, 2021).
Current Ms word generated power point presentation covers major details about the micronuclei test. It's significance and assays to conduct it. It is used to detect the micronuclei formation inside the cells of nearly every multicellular organism. It's formation takes place during chromosomal sepration at metaphase.
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/
ESR spectroscopy in liquid food and beverages.pptxPRIYANKA PATEL
With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...AbdullaAlAsif1
The pygmy halfbeak Dermogenys colletei, is known for its viviparous nature, this presents an intriguing case of relatively low fecundity, raising questions about potential compensatory reproductive strategies employed by this species. Our study delves into the examination of fecundity and the Gonadosomatic Index (GSI) in the Pygmy Halfbeak, D. colletei (Meisner, 2001), an intriguing viviparous fish indigenous to Sarawak, Borneo. We hypothesize that the Pygmy halfbeak, D. colletei, may exhibit unique reproductive adaptations to offset its low fecundity, thus enhancing its survival and fitness. To address this, we conducted a comprehensive study utilizing 28 mature female specimens of D. colletei, carefully measuring fecundity and GSI to shed light on the reproductive adaptations of this species. Our findings reveal that D. colletei indeed exhibits low fecundity, with a mean of 16.76 ± 2.01, and a mean GSI of 12.83 ± 1.27, providing crucial insights into the reproductive mechanisms at play in this species. These results underscore the existence of unique reproductive strategies in D. colletei, enabling its adaptation and persistence in Borneo's diverse aquatic ecosystems, and call for further ecological research to elucidate these mechanisms. This study lends to a better understanding of viviparous fish in Borneo and contributes to the broader field of aquatic ecology, enhancing our knowledge of species adaptations to unique ecological challenges.
Cytokines and their role in immune regulation.pptx
Nanotechnology ppt.pptx
1. Miniaturized Devices - Nanotechnology
and Biomedical Devices
Course Name: Biophysics and Nanosciences
Course Code: SIAS BT 1 3 02 C 4004
Submitted By -
Versha Rai
221254
MSc. Biotechnology
Submitted To -
Dr. Ram Gopal Nitharwal
Dept. of Biotechnology
Central University of Haryana
3. INTRODUCTION:
Nanotechnology
❖ A nanometer is one-billionth of a meter.
❖ Nanotechnology is the DESIGN, FABRICATION and UTILIZATION of MATERIALS, STRUCTURES and
DEVICES which are less than 100 nm.
Why Nanotechnology?
❖ ULTRASMALL (miniaturized) sensors, communication and navigation systems with very LOW MASS,
VOLUME and POWER CONSUMPTION are NEEDED.
4. MINIATURIZED DEVICES:
❖ Miniaturized devices are small-scale electronic or mechanical systems that have been designed
and manufactured to be significantly smaller.
❖ They have applications in various fields, including electronics, medicine, and engineering.
Examples: microchips, microsensors.
❖ Nanotechnology plays a crucial role in the development and functioning of miniaturized
devices.
5.
6. Here are some ways nanotechnology is involved in miniaturized devices:
1. Nano-scale Manufacturing: Nanotechnology enables the fabrication of tiny components with extraordinary
precision, allowing for the assembly of miniaturized devices with high levels of integration and performance.
2. Improved Materials: Nanomaterials, such as carbon nanotubes and nanoparticles, can be used to create
stronger, lighter and more conductive materials, which are essential for miniaturized devices.
3.Energy Efficiency: Nanotechnology can help reduce power consumption in miniaturized electronic devices,
extending battery life and making them more efficient.
4. Biomedical Applications: Nanotechnology has enabled the development of miniaturized medical devices
for drug delivery, diagnostics, and imaging at the cellular and molecular levels.
8. Examples of Biomedical Devices:
1. Nanoparticles for Drug Delivery:
❖ Made of biocompatible materials like lipids or polymers, can carry drugs to specific cells or tissues.
Ex - liposomal doxorubicin is used to treat cancer.
2. Nanobiosensors:
❖ Nanoscale biosensors can detect specific biomolecules or pathogens.
Ex - carbon nanotubes with antibodies can be used to detect proteins associated with diseases
3. Nanorobots for Targeted Therapy:
❖ Nanorobots, controlled remotely or autonomously, can navigate through the body to deliver drugs
or perform specific tasks, such as removing clots or cancer cells.
4. Nanoparticles for Gene Therapy:
❖ Nanotechnology is used to deliver genetic material to correct or replace faulty genes. Lipid
nanoparticles and viral vectors at the nanoscale are employed in gene therapy applications.
9. NANOTUBES-MARKING MUTATIONS:
❖ A nanodevice that will help identify DNA changes associated with cancer is the nanotube.
❖ Nanotubes are carbon rods about half the diameter of a molecule of DNA that not only can detect the
presence of altered genes, but they may help to pinpoint the exact location of those changes.
❖ To prepare DNA for nanotube analysis, scientists must attach a bulky molecule to regions of the DNA
that are associated with cancer.
❖ They can design tags that seek out specific mutations in the DNA and bind to them.
❖ Once the mutation has been tagged, researchers use a nanotube tip resembling the needle on a record
player to trace the physical shape of DNA and pinpoint the mutated regions.
❖ Nanotube creates a map showing the shape of the DNA molecule, including the tags identifying
important mutations.
❖ Since the location of mutations can influence the effects they have on a cell, these techniques will be
important in predicting disease.
12. MICROFLUIDICS (LAB ON A CHIP):
❖ The newest technologies within nanodiagnostics involve microfluidic or "lab on a chip" systems,
in which the DNA sample is completely unknown.
❖ The idea behind this kind of chip is simple: the combination of numerous processes of DNA
analysis are combined on a single chip composed of a single glass and silicon substrate.
❖ The device itself is composed of microfabricated fluidic channels, heaters, temperature sensors,
electrophoretic chambers, and fluorescence detectors to analyze nanoliter-size DNA samples.
❖ This device is described as capable of measuring aqueous reagent and DNA-containing solutions,
mixing the solutions together, amplifying or digesting the DNA to form discrete products, and
then separating and detecting those products.
❖ Using a pipette, a sample of DNA containing solution is placed on one fluid-entry port and a
reagent containing solution on the other port. Capillary action draws both solutions into the
device.