The document describes Nanonics Imaging Ltd's Nanonics Optometronic 4000 system, which provides an integrated platform for optical, electrical, and thermal characterization at the micro and nanoscale. The system uniquely combines atomic force microscopy (AFM) with near-field scanning optical microscopy (NSOM) using specialized fiber optic probes. This allows for correlated structural and optical measurements in the near and far field. The system is positioned to be a leading platform for photonics characterization in the 21st century, known as the Century of Photonics.
Scanning electron microscopy (SEM) Likhith KLIKHITHK1
Scanning Electron Microscope functions exactly as their optical counterparts except that they use a focused beam of electrons instead of light to “image” the specimen and gain information as to its structure and composition. Given sufficient light, the unaided human eye can distinguish two points 0.2 mm apart. If the points are closer together, they will appear as a single point. This distance is called the resolving power or resolution of the eye. Similarly, light microscopes use visible light (400- 700nm) and transparent lenses to see objects as small as about one micrometer (one millionth of a meter), such as a red blood cell (7 μm) or a human hair (100 μm). Light microscope has a magnification of about 1000x and enables the eye to resolve objects separated by 200 nm. Electron Microscopes were developed due to the limitations of light microscopes, which are limited by the physics of light. Electron Microscopes are capable of much higher magnifications and have a greater resolving power than a light microscope, allowing it to see much smaller objects at sub cellular, molecular and atomic level. The smallest the wavelength of the illuminating sources is the best resolution of the microscope. De Broglie defined the wavelength of moving particles (electron) λ = h/mv, Where λ= wavelength of particles, h= Planck, s constant, m= mass of the particle (electron), v= velocity of the particles; after substituting the known values, λ = 12.3 Ao/V. The resolution of an optical microscope is defined as the shortest distance between two points on a specimen that can still be distinguished by the observer or camera system as separate entities. Resolution (r) = λ/ (2NA), Where λ is the imaging wavelength, NA is objective numerical aperture. Magnification is the process of enlarging the appearance, not physical size, of something. Magnification is defined as the ratio of image distance versus object distance. M= v/u, Where M= magnification, u= object distance, v= image distance. Magnification is also defined as the ratio of the resolving power of the eye to resolving power (δ) of the microscope M= δ eye/ δ microscope.
Scanning electron microscopy (SEM) Likhith KLIKHITHK1
Scanning Electron Microscope functions exactly as their optical counterparts except that they use a focused beam of electrons instead of light to “image” the specimen and gain information as to its structure and composition. Given sufficient light, the unaided human eye can distinguish two points 0.2 mm apart. If the points are closer together, they will appear as a single point. This distance is called the resolving power or resolution of the eye. Similarly, light microscopes use visible light (400- 700nm) and transparent lenses to see objects as small as about one micrometer (one millionth of a meter), such as a red blood cell (7 μm) or a human hair (100 μm). Light microscope has a magnification of about 1000x and enables the eye to resolve objects separated by 200 nm. Electron Microscopes were developed due to the limitations of light microscopes, which are limited by the physics of light. Electron Microscopes are capable of much higher magnifications and have a greater resolving power than a light microscope, allowing it to see much smaller objects at sub cellular, molecular and atomic level. The smallest the wavelength of the illuminating sources is the best resolution of the microscope. De Broglie defined the wavelength of moving particles (electron) λ = h/mv, Where λ= wavelength of particles, h= Planck, s constant, m= mass of the particle (electron), v= velocity of the particles; after substituting the known values, λ = 12.3 Ao/V. The resolution of an optical microscope is defined as the shortest distance between two points on a specimen that can still be distinguished by the observer or camera system as separate entities. Resolution (r) = λ/ (2NA), Where λ is the imaging wavelength, NA is objective numerical aperture. Magnification is the process of enlarging the appearance, not physical size, of something. Magnification is defined as the ratio of image distance versus object distance. M= v/u, Where M= magnification, u= object distance, v= image distance. Magnification is also defined as the ratio of the resolving power of the eye to resolving power (δ) of the microscope M= δ eye/ δ microscope.
Plenary lecture given by Prof. Kenneth Gonsalves (ITT Mandi, India) on September 12, 2017 in Gramado (Brazil) during the XVI B-MRS Meeting. Acknowledgment: ITT Mandi.
Electron Beam Lithography review paper - EE541 Dublin City UniversityRay Tyndall
Nano and Microelectronic device manufacturing review paper on Electron Beam Lithography for the semiconductor industry for grading in the end of term assignment for Dublin City University module EE541.
In light microscopy, illuminating light is passed through the sample as uniformly as possible over the field of view. For thicker samples, where the objective lens does not have sufficient depth of focus, light from sample planes above and below the focal plane will also be detected. The out of focus light will add blur to the image reducing the resolution. In fluorescence microscopy, any dye molecules in the field of view will be stimulated, including those in out-of-focus planes. Confocal microscopy provides a means of rejecting the out-of-focus light from the detector such that it does not contribute blur to the images being collected. This technique allows for high-resolution imaging in thick tissues.
In a confocal microscope, the illumination and detection optics are focused on the same diffraction limited spot in the sample, which is the only spot imaged by the detector during a confocal scan. To generate a complete image, the spot must be moved over the sample and data collected point by point.
A significant advantage of the confocal microscope is the optical sectioning provided, which allows for 3D reconstruction of a sample from high-resolution stacks of images. The primary functions of a confocal microscope are to produce a point source of light and reject out-of-focus light, which provides the ability to image deep into tissues with high resolution, and optical sectioning for 3D reconstructions of imaged samples. The basic principle include illumination and detection optics are focused on the same diffraction-limited spot, which is moved over the sample to build the complete image on the detector. The entire field of view is illuminated during confocal imaging, anything outside the focal plane contributes little to the image, lessening the haze observed in standard light microscopy with thick and highly-scattering samples, and providing optical sectioning.
Plenary lecture given by Prof. Kenneth Gonsalves (ITT Mandi, India) on September 12, 2017 in Gramado (Brazil) during the XVI B-MRS Meeting. Acknowledgment: ITT Mandi.
Electron Beam Lithography review paper - EE541 Dublin City UniversityRay Tyndall
Nano and Microelectronic device manufacturing review paper on Electron Beam Lithography for the semiconductor industry for grading in the end of term assignment for Dublin City University module EE541.
In light microscopy, illuminating light is passed through the sample as uniformly as possible over the field of view. For thicker samples, where the objective lens does not have sufficient depth of focus, light from sample planes above and below the focal plane will also be detected. The out of focus light will add blur to the image reducing the resolution. In fluorescence microscopy, any dye molecules in the field of view will be stimulated, including those in out-of-focus planes. Confocal microscopy provides a means of rejecting the out-of-focus light from the detector such that it does not contribute blur to the images being collected. This technique allows for high-resolution imaging in thick tissues.
In a confocal microscope, the illumination and detection optics are focused on the same diffraction limited spot in the sample, which is the only spot imaged by the detector during a confocal scan. To generate a complete image, the spot must be moved over the sample and data collected point by point.
A significant advantage of the confocal microscope is the optical sectioning provided, which allows for 3D reconstruction of a sample from high-resolution stacks of images. The primary functions of a confocal microscope are to produce a point source of light and reject out-of-focus light, which provides the ability to image deep into tissues with high resolution, and optical sectioning for 3D reconstructions of imaged samples. The basic principle include illumination and detection optics are focused on the same diffraction-limited spot, which is moved over the sample to build the complete image on the detector. The entire field of view is illuminated during confocal imaging, anything outside the focal plane contributes little to the image, lessening the haze observed in standard light microscopy with thick and highly-scattering samples, and providing optical sectioning.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
2. THE SYSTEM
Unique Combination of
AFM and Optics
Singular Fiber Optic
Probes
Leading To A World Of Optical Characterization For
THE CENTURY OF PHOTONICS
In The Near and Far-field Structurally Correlated &
Integrated With Electrical & Thermal Measurements
The Next Evolution Integrated Optical CharacterizationTM
9. With FC/PC Connector
The connection from the
nano to micro world
The Nano
World
The Micro
World
The Next Evolution Integrated Optical CharacterizationTM
10. Interconnects near-field optics with the
worlds of nanoalignment & tests &
measurements
The Next Evolution Integrated Optical CharacterizationTM
11. NanoOptical Probes
Glass Insulated Coaxial
NanoElectrical NanoWire
Probes
NanoHeaters or
Nanothermocouples
Nanopipette Fountain Pens
for On-line Gas
Based NanoDeposition
Single Nanoparticle Scattering
Probes With A Variety of Metal
Nanoparticles Such As Co, Au, Ni
All Probes Are Non-Obscuring
With Probe
Tips Exposed From
Above Unlike
Standard Silicon Probes
All Probes are
Multiprobe friendly
A NanoToolKitTM
of Unique Multiprobe Friendly
and Optically Friendly Probes
The Next Evolution Integrated Optical CharacterizationTM
12. Simply Change The Probe To
Change The Function
The Next Evolution Integrated Optical CharacterizationTM
13. Specialized Lens fibers produced by
Nanonics and nanocharacterized by NSOM
Nanonics 3D Collage of
AFM Topography and
Collection Mode NSOM
of an Integral Fiber
MicroLens
14. Obviously Unprecedented
Profiling Can Be Done In The
Near-field and Far-field
By Collecting With the Tip
In What Is
Called Collection Mode
The Next Evolution Integrated Optical CharacterizationTM
16. Line scan of the NSOM image
ΔX=0.7 μm
2.521.510.50
2.5
2
1.5
1
0.5
0
X[µm]
Z[MHz]
The Next Evolution Integrated Optical CharacterizationTM
17. 3D NSOM distribution of the optical signal
transmitted from the surface at different distances
from the sample surface
60μm
contact
contact
5μm 15μm 20μm
30μm 40μm 50μm 60μm
10μm
The Next Evolution Integrated Optical CharacterizationTM
18. Spot width at different heights from the
surface – Normalized intensity
Contact =0.5um
5um lift =2.5um
10um lift =5.1um
15um lift =9um
The Next Evolution Integrated Optical CharacterizationTM
19. contact 5um 10um
20um15um 25um
Profile as a function of distance
The Next Evolution Integrated Optical CharacterizationTM
21. And The Optometronic 4000 also allows
for injection top and the bottom injection
as with all Nanonics platforms
The Next Evolution Integrated Optical CharacterizationTM
22. And hybrid structures are being
devised all the time in
continuous developments
APL 2010
plasmonics
integration
The Next Evolution Integrated Optical CharacterizationTM
Studied With
Collection Mode
23. Near-field phase mapping exploiting intrinsic
oscillations of NSOM aperture probe
OPTICS EXPRESS 12014, 20 June
2011 / Vol. 19, No. 13
The Next Evolution Integrated Optical CharacterizationTM
24. Fiber Lens NanoAlignment & Light Injection
Into a Silicon Waveguide lying flat on the
sample stage
The Next Evolution Integrated Optical CharacterizationTM
25. Simultaneous injection into a
silicon waveguide & evanescent
field collection
The Next Evolution Integrated Optical CharacterizationTM
26. Simultaneous injection and
evanescent field imaging
collection near-field imaging
8.0µm 8.0µm
AFM
Collection NSOM
The Next Evolution Integrated Optical CharacterizationTM
28. Evanescent wave decay as a function
of height from waveguide surface
• Single point measurement
The Next Evolution Integrated Optical CharacterizationTM
29. But often injection and imaging
the evanescent field is not enough
The Next Evolution in SPMTM
Injection
&
Collection
From the
Side
30. Nanonics NSOM/AFM Probes With
Exposed Tips Allow For Effective Side
Wall Imaging Both Optically and
Structurally
The Next Evolution in SPMTM
31. The Scanners & Probes Also
Allow For Deep Trench Imaging
Exemplary Structures Are Shown
Can Be Imaged By Nanonics Due To
Availability of::
• Large Z Scanning Range 85µ
• The Long Tip Length of 100µ
• The Very High 10:1 Aspect Ratio
Of Nanonics Tips
• And STFMTM
Which Allows A Soft
Touch AC Mode To Keep These
Large Particles In Place
10µ x 10µ AFM Image of a
0µ deep and 2µ wide trench
For Comparison
Similar Imaging
With Silicon
Cantilever
FIB Etched Trench
The Next Evolution in SPMTM
32. Illumination Mode Apertured NSOM: With
One of the First Nanonics Instruments Built
Near-field illumination
producing all k vectors for
exciting plasmonic energy
transport at will
Lens
Maier et al at Cal Tech Used Nanonics’ First
System Introduced 18 years Ago In
This Highly Cited NSOM Measurement.
This, Opened NSOM Application For Plasmon
Characterization.
The Instrumentation As With All Nanonics
Instrumentation Allowed For A Completely Free
Optical Axis From Above Allowing Independent
Placement of the Microscope Lens
and NSOM probe To Allow the Detection
of Plasmon Propagation.
The Paper Has Been Cited Over 1800 Times
The Next Evolution Integrated Optical CharacterizationTM
35. Distributed feedback laser
AFM & NSOM image
at higher injection currents
22.5mA
Collage of AFM
with Light
Distribution
2D NSOM
The Next Evolution Integrated Optical CharacterizationTM
36. High current 50 mA
NSOM & AFM
AFM
Collage of AFM with
Light Distribution
AFM 20.5 mA
for comparison
The Next Evolution Integrated Optical CharacterizationTM
37. Laser cavity height as a
function of injection current
The Next Evolution Integrated Optical CharacterizationTM
39. 1. Correlation of the
light distribution and
geometric structure of
the v groove laser
2. Notice the 150 nm
offset
3. Such information
critical to understand
the distribution of light
as compared to the
material associated
with the gain medium
4. QA of maximizing
gain
The Next Evolution Integrated Optical CharacterizationTM
42. Dual wire glass insulated
thermal conductivity probes
AFM /
Thermoresistive
Probe
AFM
Thermal Conductivity
The Next Evolution in SPMTM
43. T 0
1 mµ1 mµ
Q W R 2 9 3 - N S O M Q W R 2 9 4 - T e m p e r a t u r e
Correlation of light distribution
with thermal characteristics
The Next Evolution in SPMTM
44. The Nanonics Optometronic 4000
An Integrated Platform For
Optical Electrical & Thermal
Micro/Nanocharacterization
For
Integrated Photonics
In The 21st Century
The Century of Photonics
The Next Evolution Integrated Optical CharacterizationTM
Editor's Notes
Nanonics systems interconnecting cantilevered fiber optic probes with nanometric sample scanning stages can also be transparently integrated into light wave measuring systems.
Emphasize the separation of the probe and the lens
Distributed feedback laser structure, light distribution and collage of structure and light distribution at a low injection current
As the injection current is increased the laser heats up and there is an alteration in the topography of the laser which alters the light distribution.
Collection of light emitted by an electrically excited quantum wire laser. The difference between the left and right image is 0.8 nm in wavelength and this changes the mode structure of the laser. Such a mode structure change could only be detected with near-field optics The individual pixels in these images are about 70 nm. The spectrally selective methodology used to obtain these images is seen on the next slide.
The collection mode image was collected by the near-field optical fiber and passed through a monochromator or spectrograph to a detector. The image was then made at either 805 nm or 805.8 nm. This small wavelength change caused a large change in the distribution of light. The far-field optical resolution in this case is approximately equal to the 0.5 micron bar on the image and such a pixel size would have completely missed the possibility to image this change in light distribution with wavelength from this nanophotonic active device.
Dual-NanoWire Thermo-Resistance
In the Dual Wire Thermo-Resistance probe, two platinum wires are stretched through the nanopipette and fused together at their tips. This fused junction has a resistance that is temperature-dependent. This unique tip allows simultaneous measurement of surface topography and thermal conductivity even in intermittent contact mode. With multiple probes heat can be introduced at specific locations and detected at other locations. The probes can also be used for resistance measurements and this is indicated on the next slide.
The light distribution and the thermal imaging shows that the thermal characteristics are related to the p injection current rather than the light intensity. Such thermal and optical characterization are ideal for multiprobe systems.