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Nano- Biomimicry
Presented By:
Vishakha Vikram Deshmukh
M Pharm, Sem- I (Pharmaceutics)
Roll no. - 506
Guide:
Dr N. S. Ranpise
1
Sinhgad College of Pharmacy, Vadgaon
(Bk), Pune-41
 Innovation Inspired by Nature.
 Invention of healthier, more sustainable technologies for people.
 Medicine, biochemistry & pharmacy applications.
 Janine Benyus - Founder of Biomimicry.
Fundamentals concepts about biomimicry
Bionics - copying, imitating and learning from biology.
Biomimetics – studies and imitation of nature’s methods, mechanisms & processes.
.
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506.Vishakha
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Deshmukh
Biomimicry
Ref.- Dicks, H., 2016. The philosophy of biomimicry. Philosophy & Technology, 29(3), pp.223-243.
Kingfisher’s beak - Shinkansen bullet train.
Burr - Velcro
Ants - traffic jams
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Deshmukh
Ref.-Pathak, S., 2019. Biomimicry:(Innovation Inspired by Nature). William Morrow & Co.: London, UK, 5.
1. Nature runs on sunlight.
2. Nature utilizes only the energy it needs.
3. Nature fits form to function.
4. Nature recycles everything.
5. Nature rewards cooperation.
6. Nature banks on diversity.
7. Nature demands local expertise.
8. Nature curbs excess from within.
9. Nature taps the power of limits.
4
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Vikram
Deshmukh
Why to mimic Nature
Ref.- McGregor, S.L., 2013. Transdisciplinarity and biomimicry. Transdisciplinary Journal of Engineering & Science, 4.
Nano in Nature
I. Gecko Feet
⁃ Feet nano-size hairs.
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Vikram
Deshmukh
Ref.-Autumn, K., Liang, Y.A., Hsieh, S.T., Zesch, W., Chan, W.P., Kenny, T.W., Fearing, R. and Full, R.J., 2000. Adhesive force of a single
gecko foot-hair. Nature, 405(6787), pp.681-685.
• Gecko Biomedical developed adhesives.
• Polymer used - poly(glycerol-co-sebacate acrylate).
• Use – Seal wounds & seal holes caused by peptic ulcers.
6
506.Vishakha
Vikram
Deshmukh
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Ref.-Zhang, L., Liu, M., Zhang, Y. and Pei, R., 2020. Recent progress of highly adhesive hydrogels as wound dressings. Biomacromolecules, 21(10),
pp.3966-3983.
Cont..
7
II. Parasitic wasp
⁃ Appendage (ovipositor)- lay an egg inside her pray.
⁃ Use- delivery in difficult and delicate parts of body.
Ref.-Scali, M., Kreeft, D., Breedveld, P. and Dodou, D., 2017, April. Design and evaluation of a wasp-inspired steerable needle.
In Bioinspiration, Biomimetics, and Bioreplication 2017 (Vol. 10162, pp. 34-46). SPIE.
506.Vishakha
Vikram
Deshmukh
10/05/2022
8
III. Cicada wings
⁃ Wings of this small fly nanoscale pillar structure.
⁃ Effective against gram-negative bacteria.
⁃ Use – nanopillar coating on Surgical instruments, biomedical implants, door
handles.
506.Vishakha
Vikram
Deshmukh
10/05/2022
Ref.-Luo, L., Zhou, Y., Xu, X., Shi, W., Hu, J., Li, G., Qu, X., Guo, Y., Tian, X., Zaman, A. and Hui, D., 2020. Progress in construction
of bio-inspired physico-antimicrobial surfaces. Nanotechnology Reviews, 9(1), pp.1562-1575.
9
IV. Starfish
Starfish-Inspired Soft Robot for Advanced Therapeutics
Use - targeting, releasing, and sampling.
506.Vishakha
Vikram
Deshmukh
10/05/2022
Ref.- Zheng, Z., Wang, H., Dong, L., Shi, Q., Li, J., Sun, T., Huang, Q. and Fukuda, T., 2021. Ionic shape-morphing microrobotic end-
effectors for environmentally adaptive targeting, releasing, and sampling. Nature communications, 12(1), pp.1-12.
10
V. Pufferfish
⁃ Device to monitor ulcers and tumors.
⁃ Two layer pill (absorbent + protectant) used.
⁃ Inflates- with GI fluids, deflate- calcium solution.
⁃ Use – Monitor Ulcers & Tumors.
Ref.- Nagel, R.L., Midha, P.A., Tinsley, A., Stone, R.B., McAdams, D.A. and Shu, L.H., 2008. Exploring the use of functional models in
biomimetic conceptual design.
506.Vishakha
Vikram
Deshmukh
10/05/2022
11
VI. Bacterial flagella
⁃ Flagella rotation speed – 20,000 rpm, reverse within 1 sec.
⁃ Use- nanorobots for cargo transport, diagnosis, surgery, detoxification.
Nanomachine
506.Vishakha
Vikram
Deshmukh
10/05/2022
Ref.- Ali, J., Cheang, U.K., Martindale, J.D., Jabbarzadeh, M., Fu, H.C. and Jun Kim, M., 2017. Bacteria-inspired nanorobots with
flagellar polymorphic transformations and bundling. Scientific reports, 7(1), pp.1-10.
12
VII. Butterfly wings
Wings of rose butterfly
Use - create thin solar cells
506.Vishakha
Vikram
Deshmukh
10/05/2022
Ref.-Krishna, B.G. and Tiwari, S., 2021. Bioinspired solar cells: contribution of biology to light harvesting systems. In Sustainable
Material Solutions for Solar Energy Technologies (pp. 593-632). Elsevier.
• Nature has always been a role model for human beings and imitating the various creations of nature
helps us to solve our problems easily.
• Biomimicry uses nature as a measure. Nature is used to judge the “rightness” of our innovations.
• Biomimicry helps us view and value nature because of the various innovations that are developed
keeping nature in mind. Hence, we view nature as a mentor.
13
Conclusion
506.Vishakha
Vikram
Deshmukh
10/05/2022
14
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506.Vishakha
Vikram
Deshmukh
Reference
1. Dicks, H., 2016. The philosophy of biomimicry. Philosophy & Technology, 29(3), pp.223-243.
2. Ali, J., Cheang, U.K., Martindale, J.D., Jabbarzadeh, M., Fu, H.C. and Jun Kim, M., 2017. Bacteria-
inspired nanorobots with flagellar polymorphic transformations and bundling. Scientific reports, 7(1),
pp.1-10.
3. Ivanova, E.P., Hasan, J., Webb, H.K., Truong, V.K., Watson, G.S., Watson, J.A., Baulin, V.A.,
Pogodin, S., Wang, J.Y., Tobin, M.J. and Löbbe, C., 2012. Natural bactericidal surfaces: mechanical
rupture of Pseudomonas aeruginosa cells by cicada wings. Small, 8(16), pp.2489-2494.
4. Perera, A.S. and Coppens, M.O., 2019. Re-designing materials for biomedical applications: from
biomimicry to nature-inspired chemical engineering. Philosophical Transactions of the Royal Society
A, 377(2138), p.20180268.
5. Autumn, K., Liang, Y.A., Hsieh, S.T., Zesch, W., Chan, W.P., Kenny, T.W., Fearing, R. and Full, R.J.,
2000. Adhesive force of a single gecko foot-hair. Nature, 405(6787), pp.681-685.
6. Zheng, Z., Wang, H., Dong, L., Shi, Q., Li, J., Sun, T., Huang, Q. and Fukuda, T., 2021. Ionic shape-
morphing microrobotic end-effectors for environmentally adaptive targeting, releasing, and
sampling. Nature communications, 12(1), pp.1-12.
7. Sprang, T., Breedveld, P. and Dodou, D., 2016, July. Wasp-inspired needle insertion with low net
push force. In Conference on Biomimetic and Biohybrid Systems (pp. 307-318). Springer, Cham.
15
Thank you!
506.Vishakha
Vikram
Deshmukh
10/05/2022

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Nano-Biomimicry.pptx

  • 1. Nano- Biomimicry Presented By: Vishakha Vikram Deshmukh M Pharm, Sem- I (Pharmaceutics) Roll no. - 506 Guide: Dr N. S. Ranpise 1 Sinhgad College of Pharmacy, Vadgaon (Bk), Pune-41
  • 2.  Innovation Inspired by Nature.  Invention of healthier, more sustainable technologies for people.  Medicine, biochemistry & pharmacy applications.  Janine Benyus - Founder of Biomimicry. Fundamentals concepts about biomimicry Bionics - copying, imitating and learning from biology. Biomimetics – studies and imitation of nature’s methods, mechanisms & processes. . 2 10/05/2022 506.Vishakha Vikram Deshmukh Biomimicry Ref.- Dicks, H., 2016. The philosophy of biomimicry. Philosophy & Technology, 29(3), pp.223-243.
  • 3. Kingfisher’s beak - Shinkansen bullet train. Burr - Velcro Ants - traffic jams 3 10/05/2022 506.Vishakha Vikram Deshmukh Ref.-Pathak, S., 2019. Biomimicry:(Innovation Inspired by Nature). William Morrow & Co.: London, UK, 5.
  • 4. 1. Nature runs on sunlight. 2. Nature utilizes only the energy it needs. 3. Nature fits form to function. 4. Nature recycles everything. 5. Nature rewards cooperation. 6. Nature banks on diversity. 7. Nature demands local expertise. 8. Nature curbs excess from within. 9. Nature taps the power of limits. 4 10/05/2022 506.Vishakha Vikram Deshmukh Why to mimic Nature Ref.- McGregor, S.L., 2013. Transdisciplinarity and biomimicry. Transdisciplinary Journal of Engineering & Science, 4.
  • 5. Nano in Nature I. Gecko Feet ⁃ Feet nano-size hairs. 5 10/05/2022 506.Vishakha Vikram Deshmukh Ref.-Autumn, K., Liang, Y.A., Hsieh, S.T., Zesch, W., Chan, W.P., Kenny, T.W., Fearing, R. and Full, R.J., 2000. Adhesive force of a single gecko foot-hair. Nature, 405(6787), pp.681-685.
  • 6. • Gecko Biomedical developed adhesives. • Polymer used - poly(glycerol-co-sebacate acrylate). • Use – Seal wounds & seal holes caused by peptic ulcers. 6 506.Vishakha Vikram Deshmukh 10/05/2022 Ref.-Zhang, L., Liu, M., Zhang, Y. and Pei, R., 2020. Recent progress of highly adhesive hydrogels as wound dressings. Biomacromolecules, 21(10), pp.3966-3983. Cont..
  • 7. 7 II. Parasitic wasp ⁃ Appendage (ovipositor)- lay an egg inside her pray. ⁃ Use- delivery in difficult and delicate parts of body. Ref.-Scali, M., Kreeft, D., Breedveld, P. and Dodou, D., 2017, April. Design and evaluation of a wasp-inspired steerable needle. In Bioinspiration, Biomimetics, and Bioreplication 2017 (Vol. 10162, pp. 34-46). SPIE. 506.Vishakha Vikram Deshmukh 10/05/2022
  • 8. 8 III. Cicada wings ⁃ Wings of this small fly nanoscale pillar structure. ⁃ Effective against gram-negative bacteria. ⁃ Use – nanopillar coating on Surgical instruments, biomedical implants, door handles. 506.Vishakha Vikram Deshmukh 10/05/2022 Ref.-Luo, L., Zhou, Y., Xu, X., Shi, W., Hu, J., Li, G., Qu, X., Guo, Y., Tian, X., Zaman, A. and Hui, D., 2020. Progress in construction of bio-inspired physico-antimicrobial surfaces. Nanotechnology Reviews, 9(1), pp.1562-1575.
  • 9. 9 IV. Starfish Starfish-Inspired Soft Robot for Advanced Therapeutics Use - targeting, releasing, and sampling. 506.Vishakha Vikram Deshmukh 10/05/2022 Ref.- Zheng, Z., Wang, H., Dong, L., Shi, Q., Li, J., Sun, T., Huang, Q. and Fukuda, T., 2021. Ionic shape-morphing microrobotic end- effectors for environmentally adaptive targeting, releasing, and sampling. Nature communications, 12(1), pp.1-12.
  • 10. 10 V. Pufferfish ⁃ Device to monitor ulcers and tumors. ⁃ Two layer pill (absorbent + protectant) used. ⁃ Inflates- with GI fluids, deflate- calcium solution. ⁃ Use – Monitor Ulcers & Tumors. Ref.- Nagel, R.L., Midha, P.A., Tinsley, A., Stone, R.B., McAdams, D.A. and Shu, L.H., 2008. Exploring the use of functional models in biomimetic conceptual design. 506.Vishakha Vikram Deshmukh 10/05/2022
  • 11. 11 VI. Bacterial flagella ⁃ Flagella rotation speed – 20,000 rpm, reverse within 1 sec. ⁃ Use- nanorobots for cargo transport, diagnosis, surgery, detoxification. Nanomachine 506.Vishakha Vikram Deshmukh 10/05/2022 Ref.- Ali, J., Cheang, U.K., Martindale, J.D., Jabbarzadeh, M., Fu, H.C. and Jun Kim, M., 2017. Bacteria-inspired nanorobots with flagellar polymorphic transformations and bundling. Scientific reports, 7(1), pp.1-10.
  • 12. 12 VII. Butterfly wings Wings of rose butterfly Use - create thin solar cells 506.Vishakha Vikram Deshmukh 10/05/2022 Ref.-Krishna, B.G. and Tiwari, S., 2021. Bioinspired solar cells: contribution of biology to light harvesting systems. In Sustainable Material Solutions for Solar Energy Technologies (pp. 593-632). Elsevier.
  • 13. • Nature has always been a role model for human beings and imitating the various creations of nature helps us to solve our problems easily. • Biomimicry uses nature as a measure. Nature is used to judge the “rightness” of our innovations. • Biomimicry helps us view and value nature because of the various innovations that are developed keeping nature in mind. Hence, we view nature as a mentor. 13 Conclusion 506.Vishakha Vikram Deshmukh 10/05/2022
  • 14. 14 10/05/2022 506.Vishakha Vikram Deshmukh Reference 1. Dicks, H., 2016. The philosophy of biomimicry. Philosophy & Technology, 29(3), pp.223-243. 2. Ali, J., Cheang, U.K., Martindale, J.D., Jabbarzadeh, M., Fu, H.C. and Jun Kim, M., 2017. Bacteria- inspired nanorobots with flagellar polymorphic transformations and bundling. Scientific reports, 7(1), pp.1-10. 3. Ivanova, E.P., Hasan, J., Webb, H.K., Truong, V.K., Watson, G.S., Watson, J.A., Baulin, V.A., Pogodin, S., Wang, J.Y., Tobin, M.J. and Löbbe, C., 2012. Natural bactericidal surfaces: mechanical rupture of Pseudomonas aeruginosa cells by cicada wings. Small, 8(16), pp.2489-2494. 4. Perera, A.S. and Coppens, M.O., 2019. Re-designing materials for biomedical applications: from biomimicry to nature-inspired chemical engineering. Philosophical Transactions of the Royal Society A, 377(2138), p.20180268. 5. Autumn, K., Liang, Y.A., Hsieh, S.T., Zesch, W., Chan, W.P., Kenny, T.W., Fearing, R. and Full, R.J., 2000. Adhesive force of a single gecko foot-hair. Nature, 405(6787), pp.681-685. 6. Zheng, Z., Wang, H., Dong, L., Shi, Q., Li, J., Sun, T., Huang, Q. and Fukuda, T., 2021. Ionic shape- morphing microrobotic end-effectors for environmentally adaptive targeting, releasing, and sampling. Nature communications, 12(1), pp.1-12. 7. Sprang, T., Breedveld, P. and Dodou, D., 2016, July. Wasp-inspired needle insertion with low net push force. In Conference on Biomimetic and Biohybrid Systems (pp. 307-318). Springer, Cham.