MRI imaging of knee joint -- from radiological anatomy to pathology. inspired from my dear professor Mamdouh Mahfouz, professor of radio diagnosis - Cairo university.
MRI imaging of knee joint -- from radiological anatomy to pathology. inspired from my dear professor Mamdouh Mahfouz, professor of radio diagnosis - Cairo university.
The menisci are crescents, roughly triangular in cross section, that cover one half to two thirds of the articular surface of the corresponding tibial plateau. They are composed of dense, tightly woven collagen fibers arranged in a pattern providing great elasticity and ability to withstand compression.
The menisci are crescents, roughly triangular in cross section, that cover one half to two thirds of the articular surface of the corresponding tibial plateau. They are composed of dense, tightly woven collagen fibers arranged in a pattern providing great elasticity and ability to withstand compression.
Tips, Pearls and Pitfalls of Spinal Cord MRIWafik Bahnasy
- Many neurological disorders simultaneously or consecutively affect the brain and spinal cord, however most neurologist find their comfort zone in attending the diagnosis via the brain access.
- This concept resulted in lagging of spinal cord imaging researches compared to brain ones and consecutive underestimation of the opportunity of an important tool sometimes essential to reach a definite diagnosis.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
2. LEARNING OBJECTIVES
Identify a meniscal tear on MR images.
Describe and classify meniscal tears according to
their various subtypes.
Recognize normal meniscal anatomy and congenital
variants to improve diagnostic accuracy
3. INTRODUCTION
Accurate and timely diagnosis of a meniscal tear is critical
for reducing morbidity and planning treatment.
It is well established that meniscal damage predisposes the
adjacent articular cartilage to increased axial and sheer
stress, resulting in early degenerative osteoarthritis
4. Magnetic resonance (MR) is the preferred
noninvasive imaging modality for evaluating internal
knee derangements.
MR imaging demonstrates high sensitivity (93% for
the medial meniscus [MM] and 79% for the lateral
meniscus [LM].
5. NORMAL ANATOMY
The menisci function to absorb shock, distribute
load, assist in joint lubrication, and facilitate nutrient
distribution.
Wedge-shaped, semilunar, fibro cartilaginous
structures with superior concave surface that
conforms to the femoral condyle and a flat base
that attaches to the tibia via the central root
ligaments.
6.
7. At MR imaging, the menisci appear as low-signal-
intensity structures. Sagittal images, appear as either
a “bow-tie” structure peripherally or opposing
triangles centrally. Coronal images -- triangular or
wedge-shaped.
8.
9. MEDIAL MENISCUS
Both horns are triangular in shape and have very
sharp points. The posterior horn is always larger
than the anterior horn.
The posterior root is immediately anterior to the
posterior cruciate ligament.
The anterior root has a variable attachment, with
82% of individuals having an attachment on the flat
surface of the tibia anterior to the tibial eminence.
10.
11. The MM is less mobile because of its peripheral
attachments to the deep fibers of the medial
collateral ligament.
MM has a more open C-shaped configuration and
increases in width from anterior to posterior.
12. LATERAL MENISCUS
On sagittal images the posterior horn is higher in
position than the anterior horn. Both horns are
about the same size.
The lateral meniscus posteriorly comes up high over
the tibial spine to insert near the posterior cruciate
ligament.
15. Transverse meniscal ligament, also called the
geniculate ligament extends from the anterior horn
of the medial meniscus to the anterior horn of the
lateral meniscus.
At the attachment of the ligament onto the superior
surface of the anterior horn of the lateral meniscus,
there is commonly a high-signal-intensity line. This
line can be mistaken for an anterior horn tear.
16.
17. Meniscofemoral ligament originate from the
posterior horn of LM. The commonly recognized MFL
ligaments are the Humphry and Wrisberg ligaments,
which travel anterior and posterior to the PCL,
respectively.
Occasionally the meniscofemoral Humphry ligament
can appear as a large low-signal-intensity structure
within the notch that may resemble a displaced
meniscal fragment.
18.
19. Prominent Humphry ligament (arrow) as it approaches its femoral attachment.
Ligament can be distinguished from displaced meniscal fragment by its course on
sequential sagittal images
20. Recently, studies have reported that a far lateral
insertion of the MFL onto the posterior horn of the
LM (seen on four or more 3-mm-thick images with a
0.5-mm inter-section gap) should be considered a
probable peripheral longitudinal tear.
21. The popliteomeniscal fascicles are fibrous bands
covered by synovium that attach the posterior horn
of the lateral meniscus to the joint capsule.
Most commonly described popliteomeniscal fascicles
are the anteroinferior, posterosuperior, and
posteroinferior.
22. Sagittal T2-weighted MR image obtained depicts the posteroinferior fascicle
(arrow). Note the adjacent MFL (arrowhead)
23.
24. The oblique meniscomeniscal ligament connects the
anterior horn of one meniscus with the posterior
horn of the contralateral meniscus and is present in
only 1%–4% of knees. When present, it can simulate a
centrally displaced meniscal fragment.
25. ANATOMICAL VARIANTS
Those who interpret knee MR examinations should
be aware of the MR appearances of normal
meniscal variants that could be confused with
meniscal abnormalities.
26. Discoid meniscus
Ring lateral meniscus
Meniscal flounce
Meniscal ossicle
Chondrocalcinosis
Variation in attachment of anterior horn of MM
27. DISCOID MENISCUS
Occasionally a meniscus can extends farther onto
the articular surface of the tibia. This variant is called
a discoid meniscus. More common in the lateral
meniscus than in the medial meniscus.
Body of the meniscus measures 15 mm or more on
a midline coronal image or when three or more
bow-tie shapes are identified on contiguous sagittal
(4-mm-thick) images.
28.
29. Watanabe classification recognizes three distinct
variants of discoid meniscus:
1. the complete variant
2. the partial variant
3. the Wrisberg variant has a thickened posterior horn,
lacks the normal posterior meniscal attachments.
30. MENISCAL FLOUNCE
Rippled appearance of the free non-anchored inner
edge of the MM, which can be seen in 0.2%–0.3% of
asymptomatic knees. Typically, this is secondary to
flexion of the knee.
On coronal images, it may simulate a truncated
meniscus and mimic a radial tear.
31.
32. MENISCAL OSSICLE
A meniscal ossicle is a rare entity with a predilection
for the posterior horn of the MM. Its cause may be
developmental, degenerative, or posttraumatic.
On radiographs, the ossicle can be mistaken for a
loose body, while at MR imaging, its increased signal
intensity can mimic a tear.
33.
34. RING LATERAL MENISCUS
A ring lateral meniscus is a rare meniscal variant in
which the lateral meniscus is in the shape of a
complete.
Because of the presence of meniscal tissue adjacent
to the notch, those interpreting an MR examination
might misdiagnose this tissue as a displaced meniscal
fragment.
35.
36. CHONDROCALCINOSIS
Similar to a meniscal ossicle, chondrocalcinosis can
result in increased meniscal signal intensity,
Its prevalence increases with age and ranges from
5% to 15%. Once again, correlation with
radiographs will aid in reducing the number of false-
positive diagnoses.
37. NORMAL VARIATION IN ANTERIOR
HORN ATTACHMENT OF MM
The most distinctive normal variant seen in 15%
attachment on the anterior margin of the tibia near
the midline. The meniscus at the midportion of the
medial tibial plateau lies anterior to the tibial margin
misinterpreted as anterior subluxation.
38. An infrequent finding at the anterior horn of the
medial meniscus adjacent to the root is a ligament
extending from the meniscus to the anterior cruciate
ligament (ACL). This attachment is visualized on MRI
only occasionally; however, when it is thick, it may
appear to be a displaced meniscal fragment
39. MENISCAL TEARS
The prevalence of meniscal tears increases with age,
and meniscal tears are often associated with and
contribute to degenerative joint disease.
Tears are more common in the posterior horn of the
menisci, particularly favoring the more constrained
MM. However, in younger patients with an acute
injury, LM tears are more common.
40. CRITERIA FOR DIAGNOSING
MENISCAL TEAR
Meniscal distortion in the absence of prior surgery
or increased intrasubstance signal intensity
unequivocally contacting the articular surface, seen
on two or more images, fulfilling the “two-slice-
touch” rule, then the PPV for a tear is 94% in the
MM and 96% in the LM, and the imaging findings
should be reported as a meniscal tear.
41. If these criteria are present on only one image, then
the PPV for a tear is 43% in the MM and 18% in the
LM, and the finding is best reported as a possible
tear.
42. CLASSIFICATION
When a tear is identified, accurate description of its
morphology and tear pattern is critical for treatment
planning, as longitudinal tears are often amenable
to repair, whereas horizontal and radial tears may
require partial meniscectomy.
43. A commonly used surgical classification of meniscal tears
includes the following types:
• horizontal
• Horizontal
• Longitudinal
• Radial
• bucket handle
• displaced flap
• root
• complex
44.
45. HORIZONTAL TEAR
Runs parallel to the tibial plateau, involves either
one of the articular surfaces or the central free
edge, and extends toward the periphery, dividing
the meniscus into superior and inferior halves.
Common, representing 32% of the medial and
lateral meniscal tears.
46.
47. Often confined to the posterior horn, they may
extend into the body and anterior horn of the
meniscus.
Patients with horizontal meniscal tears often recall no
specific episode of trauma but report new or
increased knee pain after increased physical activity.
Usually occur in patients more than 40 years old
without an initiating trauma, they are sometimes
classified as degenerative tears
48. MR APPEARANCE
Appear on MRI as a horizontally oriented line of
increased intrameniscal signal that extends to the
superior or inferior surface of the meniscus near the
free edge.
Para meniscal cyst formation is associated with
complete horizontal tears that extend to the
periphery, presumably secondary to direct
communication with the joint fluid.
49.
50.
51.
52. LONGITUDNAL TEAR
Longitudinal tears run perpendicular to the tibial
plateau and parallel to the long axis of the meniscus
and divide the meniscus into central and peripheral
halves.
Pure longitudinal tears do not involve the free edge
of the meniscus.
53.
54.
55. These tears are almost always associated with a
significant knee injury, especially an ACL tear.
Propensity to involve the peripheral third of the
meniscus and posterior horns.
56. MR APPEARANCE
They are diagnosed on MRI by the presence of a
vertical line of increased signal intensity contacting
the superior, inferior, or both surfaces of the
meniscus.
It is sometimes difficult to identify peripheral
longitudinal tears in the posterior horn of the lateral
meniscus because of the complex posterior
attachments of the meniscus. In these cases, the tear
is often more conspicuous on sagittal T2-weighted
images.
57.
58. ADDITIONAL SIGNS FOR
LONGITUDNAL TEAR
Disruption of the posterosuperior popliteomeniscal
fascicle has a high PPV for tears of the LM posterior
horn and a far lateral attachment of the MFL (>14
mm beyond the lateral border of the PCL) also likely
represents a tear.
59. RADIAL TEAR
Radial tears are perpendicular to the long axis of the
meniscus. These are high energy tears.
Radial tears disrupt the meniscal hoop strength,
resulting in a dramatic loss of function and possible
meniscal extrusion
60.
61. Commonly involve the posterior horn of the MM or
the junction of the anterior horn and body of the LM.
62. MR APPEARANCE
Various imaging signs can be seen with a radial tear,
including the “truncated triangle,” “cleft,” “marching
cleft,” and “ghost meniscus” signs.
The following combination of findings is diagnostic:
In one plane: triangle missing the tip and in the
other plane: a disrupted bow tie.
63.
64.
65. The cleft sign is not specific and can be seen with
both longitudinal and radial tears, depending on the
location of the tear relative to the imaging plane.
On coronal MR images, if the cleft is within the body,
it is the result of a longitudinal tear. If the cleft is
within the horn, it is the result of a radial tear. The
opposite combination holds true on sagittal MR
images.
66. ROOT TEAR
A meniscal root tear is a radial tear located at the
meniscal root.
On coronal MR images, the root should course over
its respective tibial plateau on at least one image.
On sagittal MR images, if the posterior root of the
MM is not detected just medial to the PCL, a root
tear should be suspected.
67.
68. Meniscal root tears are often associated with
extrusion of the meniscus beyond the margin of the
tibial plateau. More than 3 mm meniscus extrusion is
often associated with tears involving the meniscal
root.
69.
70. When there is a complete radial tear, the two
meniscal fragments can be completely
separated. This can result in an empty meniscal space
or empty meniscus sign (arrow).
71.
72. COMPLEX TEAR
A complex tear includes a combination of radial,
horizontal, and longitudinal components (any two
or all three). Often the meniscus appears
fragmented, with the tear extending in more than
one plane.
73.
74. DISPLACED TEAR
Displaced tears include free fragments, displaced flap
tears, and bucket-handle tears.
These tears often manifest with mechanical obstruction
and require surgery.
It can sometimes be difficult to find the displaced
fragment at arthroscopy; if it is not removed, there is often
persistent knee pain and locking.
75. Flap tears more frequently in the MM, where in two-
thirds of cases, fragments are displaced posteriorly
(near or posterior to the PCL) in the remaining cases,
fragments course into either the intercondylar notch
or superior recess.
In the LM, fragments are equally distributed along
the posterior joint line and lateral recess.
76.
77.
78. BUCKET HANDLE TEAR
A bucket-handle tear is a longitudinal tear with central
migration of the inner “handle” fragment.
This tear pattern occurs seven times more frequently in the
MM.
It has at least five different MR imaging signs: an absent bow
tie, a fragment within the intercondylar notch, a double PCL,
a double anterior horn or flipped meniscus, and a
disproportionally small posterior horn.
A bucket-handle tear of the LM -- a double ACL sign.
79.
80.
81. Although these signs are sensitive, they are not
specific.
Absent bow-tie sign, where the innermost bow tie is
not present, can also be seen in a small or pediatric
patient and with a radial tear of the body, macerated
meniscus, or prior partial meniscectomy.
Mimics of the double PCL sign include a prominent
ligament of Humphry, a meniscomeniscal ligament,
and intercondylar osseous bodies
82. INDIRECT SIGNS
Secondary or indirect signs of a meniscal tear are
MR imaging findings that can accompany meniscal
tears. These signs can increase the reader’s
diagnostic confidence.
Have low sensitivity, they have high specificity and
high PPVs for an underlying tear.
84. CONCLUSION
MRI is a highly accurate imaging method for diagnosing
meniscal tears.
MR imaging allows accurate characterization of various
tear patterns, which can be instrumental for patient
counseling and surgical planning.
To avoid errors in diagnosing meniscal tears, those
interpreting MR examinations of the knee need to be
aware of the attachments of the menisci and the normal
variations in meniscal anatomy that may resemble a
meniscal tear.
Editor's Notes
, serving as anchors and maintaining the normal meniscal position and biomechanical function
modified Watanabe classification includes a ring-shaped meniscus with connection between the roots. This variant can mimic a medially displaced meniscal fragment; however, no donor site can be identified at imagin
The key MR features that differentiate a ring lateral meniscus from a displaced meniscal fragment are the perfect isosceles triangle appearance of the meniscus within the central portion of the joint and the absence of a defect in the remainder of the meniscus
The surface extension may be subtle in some patients because these tears have extensive fibrillation on the surface. This fibrillation results in interdigitated surface fibers so the internal signal may not definitely contact the meniscal surface on MRI. When it is difficult to be certain of surface contact of the internal signal, I am more confident of the diagnosis of a horizontal meniscal tear when the intrameniscal signal has the intensity of fluid on T2-weighted images
MR imaging appearance of a radial tear, which varies depending on whether the imaging sequence is performed orthogonal (1 and 3) or in plane (2 and 4) to the orientation of the tear
Meniscal root tear: on sagittal images there is an absent or empty meniscus-sign adjacent to the posterior cruciate ligament where the meniscal root should be. On coronal images a meniscal root tear is confirmed.