This document discusses colposcopic findings related to various cervical conditions:
1. It describes the appearance of different types of cervicovaginitis including red punctate, white punctate, focal, and follicular cervicitis.
2. It notes the pale, smooth, dry appearance of the cervix in cases of cervical atrophy.
3. Various cervical polyps are described such as mucous polyps, adenomatous polyps, and fibrous polyps.
4. Cervical papillomas are described as exocervical polyps that are often seen during pregnancy.
5. True cervical erosions appear as denuded epithelium with newly formed capillaries
This presentation describes about the cause, parthenogenesis, risk factors, clinical diagnosis, symptoms, complications and treatment of salpingitis (Hydrosalpinx). This presentation also consist a real case.
Colposcopy training part 1 ,DR. SHARDA JAIN Dr. Jyoti Agarwal / Dr. Jyoti Bha...Lifecare Centre
Definition used in the consensus guidelines ASCCP +24 organizations 2013
Colposcopy
Colposcopy is the examination of the cervix , vagina and, in some instances the vulva, with the colposcope after the application of a 3--5% acetic solution coupled with obtaining colposcopically – directed biopsies of all lesions suspected of representing neoplasia
This presentation describes about the cause, parthenogenesis, risk factors, clinical diagnosis, symptoms, complications and treatment of salpingitis (Hydrosalpinx). This presentation also consist a real case.
Colposcopy training part 1 ,DR. SHARDA JAIN Dr. Jyoti Agarwal / Dr. Jyoti Bha...Lifecare Centre
Definition used in the consensus guidelines ASCCP +24 organizations 2013
Colposcopy
Colposcopy is the examination of the cervix , vagina and, in some instances the vulva, with the colposcope after the application of a 3--5% acetic solution coupled with obtaining colposcopically – directed biopsies of all lesions suspected of representing neoplasia
Sonosalpingography. Dr. Sharda Jain, Dr. Jyoti Agarwal Lifecare Centre
Evaluation of fallopian tubes forms an essential part of evaluation
Tubal pathology is a cause of infertility in 30- 35% of infertile patients
Tubal Assessment
Fallopian tubes can be assessed by:
Hysterosalpingography
Hysterosalpingo-contrast-sonography (HycoSy)
Sonosalpingography
Laparoscopy & CHROMOTUBATION
A cervical biopsy is a procedure to remove tissue from the cervix to test for abnormal or precancerous conditions, or cervical cancer. The cervix is the lower, narrow part of the uterus. It forms a canal that opens into the vagina. Cervical biopsies can be done in several ways.
Given the availability of a colposcope and a trained colposcopist this method is an essential tool for effective secondary prevention of female reproductive organ diseases. Colposcopic guided procedures enable a preceise diagnostic and consequent treatments with eventually organ preserving means. This power point presentation highlights the range of opportunities offered by Colposcopy.
Sonosalpingography. Dr. Sharda Jain, Dr. Jyoti Agarwal Lifecare Centre
Evaluation of fallopian tubes forms an essential part of evaluation
Tubal pathology is a cause of infertility in 30- 35% of infertile patients
Tubal Assessment
Fallopian tubes can be assessed by:
Hysterosalpingography
Hysterosalpingo-contrast-sonography (HycoSy)
Sonosalpingography
Laparoscopy & CHROMOTUBATION
A cervical biopsy is a procedure to remove tissue from the cervix to test for abnormal or precancerous conditions, or cervical cancer. The cervix is the lower, narrow part of the uterus. It forms a canal that opens into the vagina. Cervical biopsies can be done in several ways.
Given the availability of a colposcope and a trained colposcopist this method is an essential tool for effective secondary prevention of female reproductive organ diseases. Colposcopic guided procedures enable a preceise diagnostic and consequent treatments with eventually organ preserving means. This power point presentation highlights the range of opportunities offered by Colposcopy.
A brief anatomical, embryological, patho-physiological and surgical description of the Vermiform Appendix.
Surface Anatomy of Appendix, Appendicectomy, surgical approach, complications, Appendicular lump and abscess, Neoplasia, Carcinoid syndrome, Pseudomyxoma Peritonei, The Alvarado Score
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Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
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The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
2. 1. Cevicovaginitis
I.Red punctate vaginitis:
Over a pale pink background, some red dots are
seen which extends diffusely. The red spots are
iodine negative. Tricomonas vaginalis in 50% of
cases
ii.White punctuate vaginitis:
white dots on hyperaemic mucosa. Fungus in
95% of cases.
AHOUBAKR ELNASHAR
4. iii. Focal vaginitis:
Some red spots or stains & in between unchanged
mucosa with increased vascularity.
Tricomonas vaginalis in 98% of cases
iv. Follicular cervicitis:
Creamy white, raised, rounded swellings under
ectopic columnar epithelium & immature metaplastic
squamous epithelium. Acetic acid test or Schiller
iodine test do not change the picture.
It is associated with chlamydia infection
v. Atrophic vaginitis:
Red spots on atrophic mucosa.
AHOUBAKR ELNASHAR
5. 2. Atrophy
The mucosa is pale, smooth, dry, thin
,squamocolumnar junction may disappear in the
cervical canal.
Fine network of capillaries. Iodine test is negative
(devoid of glycogen)
AHOUBAKR ELNASHAR
7. 3. Polyps
i. Mucous polyps:
small, pink & relatively smooth surface, upon which
it is possible to observe the fissures of the normal
endocervical tissue.
After acetic acid, it becomes paler. If there is
metaplasis, with acetic acid whitish zones appear.
AHOUBAKR ELNASHAR
8. ii. Adenomatous polyp:
colposcopic picture is quite similar to that of ectopy
iii.Fibrous polyp:
Larger with firmer consistency, surface is smooth,
purple with frequent petichae, necrotic zones
AHOUBAKR ELNASHAR
10. 4. Papilloma
is exocervical polyps
It is most frequently seen during pregnancy. They
may have the appearance of columnar epithelium
with a much more clearly visible central capillary
network. Each papilla is long.
It is often multifocal.
After actic acid, the vessels in papilloma usually
completely disappear.
AHOUBAKR ELNASHAR
11. 5. True erosion
denuded epithelium.
Loss of epithelium is followed by formation of
granulation tissue & subsequent epithelization with
abundance of newly formed capillaries.
It is bright red with so rich vascularization.
AHOUBAKR ELNASHAR
12. 6. Update of colposcopy of genital HPV
Meisels et al (1982):
Florid,
spiked,
flat,
condylomatous vaginitis.
Flat condyloma & mild dysplasia represent the same
biologic phenomenon, namely, productive HPV
infection (Reid,1993).
The expression of viral activity may be clinical or
subclinical when it is recognizable only on
colposcopy.
AHOUBAKR ELNASHAR
13. Exophytic & flat condylomata are not homologous
diseases.
Exophytic is usually caused by cutaneotropic viruses
(6,11).
Flat are more likely to contain
medium (31,33) or
high risk (16,18) HPV types.
Micropapillary condyloma should not be confused
with micropapillomatous labialis.
AHOUBAKR ELNASHAR