This document discusses migration and health, focusing on an Africa-centered research agenda. It notes renewed global focus on migration through frameworks like the SDGs and WHO, but also competing political agendas around securitization of migration. Four priority areas are identified for achieving the WHO resolution on migrant health: monitoring health, partnerships, sensitive health systems, and policy frameworks. The document then focuses on migration trends in Southern Africa involving mixed flows, vulnerabilities, and implications for public health responses and overburdened systems. Structural violence and anti-foreigner attitudes are also raised as challenges. It concludes by calling for a public health approach, renewed regional conversation, and scaling up of good practices.