MDI (metered dose inhaler) is a device that used to deliver a specific amount of medication to the lungs.

1. Welcome
to
MDI presentation
By Md. Tareq Aziz
Md. Ariful Mondol Arif
Md. Jahid Khan
Joydeb Roy
Bangladesh University
Department of Pharmacy

2. MDI
Metered Dose
Inhaler

3. Definition of MDI.
MDI (metered dose inhaler) is a
device that used to deliver a specific
amount of medication to the lungs.
Metered dose inhalers were first
developed in 1955 by Riker
Laboratories, Now a subsidiary of 3 M
Healthcare.

4. Metered Dose Inhaler (MDI) has a
pressurized container of medication that
fits into a mouthpiece,
A dose of medication is released into
lungs by pushing the container into the
mouthpiece.

5. Components of MDI
1. Canister:
The canister which is produced in aluminium
or stainless steel , where the formulation
resides.
2. Actuator:
The complete made canister is fitted into a
plastic container this is called actuator, which
allows the patient to operate the device and
directs the aerosol into the patient lungs.

6. 3. Metering valve:
It allows a metered quantity of the
formulation.
4. Actuator seat:
It holds metering valve and actuator nozzle.
5. Actuator nozzle:
It helps to spread the component into the
mouth.

7. Fig: Components of MDI

8. Types of MDI.
MDIs (Metered Dose Inhaler) are classified
in two categories
1. Non-pressurized MDIs.
2. Pressurized MDIs.

9. 1. Non-pressurized MDI.
Portable, inhalation delivery device
containing an aqueous solution,
suspension or emulsion , which
delivers one dose in one or more
actuators.
2. Pressurized MDI.
An inhalation product containing one
or more propellants in a pressurized
delivery device.

10. How to use meter dose
inhaler:
1. At first the Inhaler should be
Shaken very well before use.
2. Then the cap should be removed.
3. Breath out away from inhaler.
4. Then the inhaler should be brought
to mouth, placed it in mouth
between teeth and closed mouth
around it.

11. 5. Then the patient should start to
breathe in slowly, press the top of
inhaler once and keep breathing in
slowly until patient has taken a full
breath.
6. At last the patient should Remove the
inhaler from mouth and hold breathe
for about 10 seconds, then breathe out.

12. Fig: how to use
MDI

13. Advantages of MDI.
There are a number of advantages that
are consider with metered dose inhaler,
which are written below.
1. It reduces dose lose.
2. allows pressurized metered dose.
3. inhaler use in patient with acute
illness.
4. It deliver specific amount of
medication to patients.
5. No drug preparation is needed.

14. 6. It is small size & convenience to
patients.
7. Usually, it is inexpensive as
compared to Dry Powder Inhaler(DPI) &
Nebulizer.
8. Quick to use than other device.
9. It has multi-dose capability, more
than hundred (100) dose are available.

15. Disadvantage of MDIs.
1. Accessory device decreases
portability.
2. Additional cost.
3. Possible dosing error.
4. Potential source of contamination or
infections.
5. there is no information about the
number of dose left in the MDI.
6. Proper co-ordination is essential.
7. Difficult to deliver high dose.

16. Problem connected with MDI.
1. Canister not shaken energetically
before delivery.
2. Patient breathes in before delivery.
3. Patient breathes in after delivery.
4. Patients breathes out during
delivery.
5. Patient delivers multiple doses
during the same breath.

17. 6. Patient breathes out before inhalation
is complete.
7. Drugs delivery and inhalation are not
simultaneous.