Malaria is a protozoal disease transmitted to humans by infected Anopheles mosquitoes. In Nepal, approximately 13 million people live in malaria endemic areas, with 1 million in high risk areas. The disease is most prevalent in the Terai region. Two species, Plasmodium vivax and P. falciparum, are found in Nepal, with 80% of cases being P. vivax. Nepal has experienced malaria outbreaks since the 1970s and has worked to control the disease through a national malaria program since the 1950s. The current strategic plan aims to eliminate malaria in Nepal by 2025.