The document summarizes the mythological origins, classification, signs and symptoms of loota visha (spider venom poisoning) according to Ayurveda. It describes the venom's effects based on dosha involvement and the site of envenomation (e.g. breath, teeth, excreta, etc.). Symptoms include swelling, fever, burning sensation, itching and pain that progress over days, potentially causing death within a week if left untreated. The venom has properties of all three doshas and can cause a variety of internal diseases if it invades vital organs.
Approximately more than three thousand species of snakes are documented to date; among these, nearly two hundred and fifty are found in the Indian sub-continent, and approx. fifty of these are poisonous.
Approximately more than three thousand species of snakes are documented to date; among these, nearly two hundred and fifty are found in the Indian sub-continent, and approx. fifty of these are poisonous.
in ayurvedic pharmacology some drugs have action according to their aura. this aura treat patients in various aspects eg wearing of jems and different stones
the concept of virya gives the knowledge of potency of drugs it is well explained by Virya. the action of the drugs depends on the potency presents in it.
the ppt gives detailed knowledge of Karma that are described in Ayurveda Dravyaguna (Ayurvedic Materia medica) it is useful to treat the patients by Ayurvedic way.
Asrigdara is an Ayurvedic term for Abnormal Uterine Bleeding. It is one of the most common gynecological problems found in Stri Rog OPD. I have tried to compile all the important points mentioned in various Ayurveda Literatures regarding Asrigdara.
in ayurvedic pharmacology some drugs have action according to their aura. this aura treat patients in various aspects eg wearing of jems and different stones
the concept of virya gives the knowledge of potency of drugs it is well explained by Virya. the action of the drugs depends on the potency presents in it.
the ppt gives detailed knowledge of Karma that are described in Ayurveda Dravyaguna (Ayurvedic Materia medica) it is useful to treat the patients by Ayurvedic way.
Asrigdara is an Ayurvedic term for Abnormal Uterine Bleeding. It is one of the most common gynecological problems found in Stri Rog OPD. I have tried to compile all the important points mentioned in various Ayurveda Literatures regarding Asrigdara.
shotha nidana, poorva roopa, roopa, upashaya, samprapthi, chikitsa according to charaka, sushrutha, ashtanga hridaya, ashtanga sangaraha
you can get detail description on shotha from this presentation.
Samhita Adhyayan - 1st Profession, Charak Samhita Sutrastan's 2nd Chatushka - Swastha chatuska and 5th Chapter- Matrashitya Adhyay's 2nd topic Swasthavrut Varnan in relation to the Shalakya Tantra.
It includes a Breif description of Nasya and Dhumapana in Contex to Daily Regiman.
A brief description includes:
Definition, Synonyms, Mode of Actions, Types, Advantages, Indications, Contraindications, Theraputic Procedures and Procedure Videos.
Srotas.pptx Everything about srotas in short.Pakhi Sharma
Detailed description on srotas definition, classification, Paryaya, atructure, pramukhyata, sroto dushti, sroto dushti prakara, viddha lakshana. Short and appropriate jest of some examination-related important topics in Roga Nidana. Important for quick revision for 1st year (Kriya and Rachana sharira)and also 2nd year (Roga nidana) professional B.A.M.S. Undergraduate degree.
The ppt involves brief srotas description along with flow charts and important shlokas.
The word parihara states that avoidance of apathy a (bad diet/regimen) during and after shodhana. The Ahara and Vihara must be avoided during and after shodhana karma is called as parihara vishaya.During panchakarma therapies one should avoid excessive sitting, standing, speaking and riding, sleep
during day time, sexual intercourse, suppression of natural urges, cooling regimens, exposure to sun, grief,
anger and intake of untimely and unwholesome food.
Samsarjana krama explains about diet sequence in which persons should adopt the healthy diet
from laghu aahara (light diet) to guru ahara (heavy diet) in order to increase agni.
Video link- https://youtube.be/VHv6JgKTsaU
1. Full description of ark(madar)/Calotropis.(both classical,mordent and research points covered).
2. ark as semi-poison.
3. Desription,preparation and indications of ark lavan and ark tail.
4. Some demonstrations using ark leaves and flowers in common disorders.
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Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
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2. Contents
*Introduction * असाद्य लकण
*Origin * चिचकत्सा
*Classification * Spiders
* अचिष्ठान
* सामन्य लक्षण
* लक्षण acc. to दोष’ s and stage wise
3. Introduction
Definition of अगद तन्त्र
अगदतन्त्रं नाम सर्पकीट लूता मूषकाचद दष्ट चिष व्यञ्जनार्थं
चिचिि चिषसंयोगोर्र्पमनार्थपञ्च | ( सु. सु.१/१४)
4. Mythological origin of लूता :-
1.Drops of sweat on the forehead of sage vasistha, who was
angered by King Vishwamitra, which fell on the cut grass
transformed themselves into Loota (spiders)."
2. During the burning of Khandava forest, the sparks of fire
which came from the body of asuras/demons became loota.
3. One more opinion states that intake of दुष्ट अन्न or
contaminated food might lead to formation of visha sphota.
5. Classification of लूता
1. Based on दोषप्रकोप
A. िायव्य - causes िातरोग and are उद्
चिदा - are 7 in number.
B. आग्नेय - causes चर्त्तज रोग originated by स्वेद are 7 in number.
C. सौम्य - causes कफजन्य चिकारा originated by अण्डज are 7 in number.
D. चमश्र - It's चिष spreads very quickly also called as उर्र्ाचदका.
6. 2. Based on the विष प्रभाि लूता are 3 types
तीक्ष्ण मध्य अिरत्वेन ध्नन्ति िाऽऽशु अविवकन्तितााः
सप्ताहेन दशाहेन पक्षेण ि परं क्रमात्।। (अ.सं.उ. ४४/५)
a. तीक्ष्ण चिषयुक्त- Death will occur in 7 days following bite.
b. मध्यम चिषयुक्त- Death will occur in 7-10 days following bite.
c.मन्द चिषयुक्त- Death will occur in 15 days following bite.
7. 3. Based on साध्यसाध्यता
क
ृ च्छ्
र साध्य तथा असाध्या लूतास्तु विविधााः स्मृता
तासामष्टौ क
ृ च्छ्
र साध्या िर्ज्ाास्ताित्य एि तु ।। (सु.क. ८/९४)
● क
ृ च्छ्
र साध्या- difficult to cure, they are in mumber.
● असाध्या - incurable, 8 in number.
10. General Symptoms of the bite of लूता
● दद्रुमण्डल apperance of round rash
● चसत white
● अरूण mild red
● र्ीत yellow
● श्याि blue in colour.
● मृदु उन्नत soft and raised up
● मध्ये क
ृ ष्ण अर्थिा the centre is either black or blue
11. •श्याि र्यपन्त जालकािृत: resembling a net at its edges.
•चिसर्पिान र्ोफयुतस्तप्यते-Burming sensation and swelling spreads sideways.
•बहुिेदन severe pain
•ज्वर fever
•र्ाक under goes quick ripening/ulceration
•चिक्लेद exudation
• कोर्थ purification and loss of tissues
•क्लेदेन यत स्पृर्त्यङ्ग when the pus from the wound comes
•तत्राचर् क
ु रुते व्रण contact with other parts new ulcers are formed on those
parts.
12. चिष लक्षण according to vitiation of
दोबा’ऽ
Generally the poison of the लूता have properties of all चत्रदोष 's and
they give rise to following diseases.
दंश: वपत्तात्मको दाह तृट्स्फोट्स ज्वर दाहिान् ।
सशोफाः कविनाः पाण्डुाः कण्ड
ू मान् श्लेन्तिकोल्परुक
् ॥ .
िावतकाः परुषाः श्यािाः पिाभेदावदरुक्कराः ।। (अ.सं.उ. ४४/१७)
14. चिष लक्षण According to Day wise
चदनािप लक्षयते नैिं दंर्ो लूताचिषोद्भि:
The lesion at the site of the bite by loota does not manifest
for half a day.
On 1st Day
1. सूिीव्यििदािाचत appears as though pricked by a needle
2. अव्यक्त िणप no change in colour in affected part
3. रुक and कण्ड
ू slight pain and itching
15. 2nd Day:
1. उन्नत -edges are raised
2. चर्टक - surrounded by eruptions
3. व्यक्त िणप- change in the colour of skin
4. नतो मध्ये depressed in the centre
5. कण्डु - has itching
6. ग्रन्थि - resembles a tumour
3 Day:
1. ज्वर- fever
2. रोमहषप - horripilation
16. 3. र्रािरूर्स्तोद-red circular patches with shape of soucer associated with pain.
4. रोमक
ू र्ेषु सास्रि: bleeding from the hair follicle.
4th Day
1. श्वयर्थु- there is profound swelling
2. तार् - temperature is raised
3. श्वास- dyspnoea
4. भ्रम - giddiness
17. On 5th Day
1. It give rise to symptoms of poisoning related to the dosa.
On 6th Day
1. व्याप्नोचत ममप - The poison invades all the vital organs.
On 7th Day
1. हन्थन्त जीचितम- The poison invades all the vital organs
18. Signs and Symptoms According to the
site of poison
1. By Breath श्वास
श्वासेन दंर्: सहसा र्ूयते ज्वरदाहिान।
1.र्ूयते - swelling
2.ज्वर - fever
3.दाह -burning sensation
20. 3. By Excreta र्क
ृ त
दुगपन्धी र्क
ृ ता दाह कण्ड
ू चिचमचिमान्थितः ।
र्च्यते िार्ु र्क्वश्च र्ाण्डुः र्ीलुफलोर्मः ।। (अ.सं.उ.४४/१६-१७)
•दुगपन्धी - foul smelling
• दाह - burning sensation
•कण्ड
ू - itching
•चिचमचिमाान्थित - feeling of pins and needles
•र्च्यते र्ार्ु - ripens quickly
•र्क्वश्च र्ाण्डु : - When ripe it is yellowish colour
21. 4. By Urine मूत्र
मूत्रेण रक्तर्यपन्तो मध्ये क
ृ ष्णो चिर्ीयपते । आितपसदृर्ः र्ूनः र्ूचतः सर्पचत
दध्यते ||
•रक्तर्यपन्तो मध्ये क
ृ ष्णो चिर्ीयपते swelling has red colour and black
centre
•आितपसदृर्ः resembles a whirl
•र्ून: र्ूचतप emits foul smell
•सर्पचत spreads outwards
•दध्यते has burning sensation
22. 5. By Semen र्ुक्र
र्ुक्र
े ण ग्रन्थिसंथर्थान: कचिन स्तीव्र िेदनः ।
•ग्रंचर्थ संथर्थान swelling resembles a tumour
•कचिन is hard
•तीव्र िेदन: very painful
6. By Saliva लालास्राि
अल्प मूलोल्परुिकोङ्गो लालया कण्डुरो मृदुः । (अ.सं.उ. ४४ / १८-१९)
23. •अल्पमूलो elevated rash which is not elevated
• अल्परुक्कोटो little pain
• कण्डुरो itching
• मृदु soft to touch
7. By nails
नखेन िोष चर्टका कण्ड
ू िूमायनान्थितः ।
• िोष burning sensation
•चर्टका eruptions
24. •कण्ड
ू itching
• घूमायनान्थित feeling as though smoke is coming out
8.By Menstrual blood - रजसा
चक
ं र्ुकोदर िणपस्तु रजसा िञ्िुमालिान |
•चक
ं र्ुकोदर िणपस्तः eruptions appear having colour of चक
ं र्ुक
flowers (red)
•िञ्िुमालिान resembles a garland
30. SPIDERS
● There are at least 50,000 spider species in the arachnid family
● Spiders are defined as having eight jointed legs, no wings, no
antennae and only two body sections: the thorax and the abdomen.
● All spiders have some amount of venom with varying degrees of
potency.
● The venom is injected through the hollow fangs into the victim.
● The venom will rapidly paralyze the victim and aid in digestion.
● Fortunately, most spiders are not dangerous to humans because
their fangs are either too short or too to penetrate human skin.
31. Symptoms :-
1. Body as a whole
Pain similar to a bee or wasp sting at the site of the bite.
Sense of swelling of lips and throat .
1. Respiratory
Difficulty in breathing
1. Eyes,ears,nose and throat
Angioedema (eye lid puffiness)
32. Skin temperature over the bite area tends to be warmer than the
surrounding area.
4. Skin
Redness
Rash
Itching
Swelling at the site of bite
5. Heart and blood vessels
Rapid heart rate and low blood pressure .
33. Brown Recluse Spider
•The brown recluse spider is also known as the violin spider or fiddleback spider.
•It is a venomous spider, Loxosceles reclusa, of the family Sicariidae.
• It is usually between 1/4 and 3/4 inch but may grow larger.
•It is brown and usually has markings on the dorsal side of its thorax, with a
black line coming from it that looks like a violin with the neck of the violin
pointing to the rear of the spider resulting in the nickname "fiddleback spider" or
"violin spider".
•It has six eyes rather than the typical eight and the tail-end segment has no
markings.
34. Scientific Classification
Kingdom - Animalia
Phylum - Arthropoda
Class- - Arachnida
Order - Araneae
Family - Sicariidae
Genus - Loxosceles
Species - L.reclusa
35. Binomial name Loxosceles reclusa
It usually bites only when pressed against human skin such as when putting on an
article of clothing.
Symptoms
•The wound takes on a bull's-eye
appearance, with a center blister
surrounded by an red ring and
a blanched or white ring.
36. •The bite produces a mild stinging, followed by local redness and intense
pain within eight hours.
•The fluid-filled blister then sloughs off to leave a deep, enlarging ulcer.
•The ulcer can enlarge and involve underlying skin and muscle tissue.
•Pain may be severe.
•A generalized red, itchy rash usually appears in the first 24-48 hours.
•Other symptoms include fever, chills, nausea, vomiting, muscle aches
and hemolytic anemia.
•On rare occasions death results ,more often in children.
37. Black Widow Spider
Binomial name - Latrodectus mactans
Scientific Classification
Kingdom - Animalia
Phylum - Arthropoda
Class - Arachnida
Order - Araneae
38. Family - Theridiidae
Genus - Latrodectus
Species - mactans
•Latrodectus includes approximately 31 recognized venomous species, with
the black widow spider being the best known member of the group.
•Widow Spiders carry a neurotoxic venom.
•The black widow spider is a shiny, inky black spider with a large round tail
segment (abdomen), generally measuring from one-half inch to one inch in
length.
•Widow spiders are large, strong-looking house spiders.
•The abdomen is dark and shiny, and has one or several red spots, either
above or below.
39. •Male widows, like most spiders, are much smaller than the females and are
generally considered to be much less dangerous than the females.
•Widows tend to be quite non-aggressive, but will bite if the web is disturbed
and the spider feels threatened.
Symptoms
•The bite feels like a pinprick.
•A black widow spider bite gives the
appearance of a target, with a pale
area surrounded by a red ring.
40. •At first you may notice only slight swelling and faint red marks.
Within a few hours, intense pain and stiffness begin.
•Other signs and symptoms include-chills, fever, nausea, severe
abdominal pain etc.
•Severe muscle pain and cramps may develop in the first two hours.
•Severe cramps are usually first felt in the back, shoulders, abdomen
and thighs.
•Other symptoms include weakness, sweating, headache, anxiety,
itching, nausea vomiting, difficult breathing and increased blood
pressure.
42. •They are a mottled gray-brown color.
•They are aggressive, come after their prey and are fast
runners.
•Bites from a wolf spider can cause pain, redness and swelling.
•The large jaws/fangs can cause a tear in the skin as they bite.
Swollen lymph glands may develop.
•The skin area at the bite may turn black.
•Swelling and pain can last up to ten days.
44. •Handling a tarantula can result in irritation to the skin.
•If hands are not washed after handling a tarantula
and eyes are touched the sharp hairs can cause eye irritation.
•Their bites can be quite painful
because of the large size of the
spider.
45. Treatment
• Clean the wound with mild soap and water. Apply an antibiotic
ointment three times a day to help prevent infection.
•Apply a cool compress over the bite for 15 minutes each hour. Use
a clean cloth dampened with water or filled with ice. This helps
reduce pain and swelling.
• If possible, elevate the affected area.
• Take an over-the-counter pain reliever as needed.
•If the affected area is itchy, an antihistamine, such as
diphenhydramine (Benadryl) or certirizine (Zyrtec), might help.
46. References
1) Classical ref – Ashtanga Hridaya, Ashtanga Sangraha
Sushruta Samhita, Charaka Samhita.
2) Modern aspect- Goutham Biswas, K. S Narayan
Reddy.