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Jeev jagat Om ki Adharshila
Diagram of Cell membrane
Lady of Hats – Wc – Public domain
Nanoscale image of the membrane of a living cell-a bacillus
Oak Ridge National Laboratory- Mike Mcrae –Nature-Science alert.com
Jeev Jagat poem ki Adharshila
Cell membrane
They call me cell membrane
But I am really Plasma membrane
A thin flexible bilayer of amphipathic lipids
embedded with a variety of proteins
containing all the contents of a cell
within my ambit and making a cell
look like a baloon filled with fluid
in which smaller baloons or capsules
of various types were floating freely
as if in a pool .
That gell like fluid – the cytoplasm
Those minuscule bodies – the organelles
are my precious possessions & protégé!
in my care and protection always.
I surround the cell like a fort wall
with gates controlling entry & exit of all
made possible by my constituents and structure
turning me into a unique bio film of one and all
Jeev jagat Ki Adharshila
My lipid components are mainly three
Phospholipids ,Glycolipids and Sterols
inbuilt in me
but phospholipids with hydrophilic heads
and long hydrophobic tails predominate
They keep me in liquid crystalline state
The Cholesterol stiffens ,strengthens
and regulates my fluidity always
even when temperature fluctuates.
Together all these three are responsible for
my main characteristics.
My proteins are also mainly three
Of Integral ,anchored and peripheral types
responsible for many of my features,
roles and activities.
The integral ones are transmembrane proteins spanning me
including protein channels ,proton pumps ,as well as
G protein coupled receptors which are major players
in signaling and transportation across me.
Jeev Jagat ki Adharshila
The ion channels allow ions and small molecules
to diffuse and also determine my electricalproperties
Among the peripheral proteins
are some Enzymes and some hormones ,
which along with anchored G proteins
play great role in transmission of signals
I am not a semipermeable membrane only
but am also involved in many other activities
such as cell adhesion ,and ion conductivity, ;
And I also act as an attachment for cell wall
and carbohydrate calyx on the outer side and
the cytoskeleton on the inside, of a cell.
And now you tell me Sir
Am I not an organelle myself ?
or like one and as important
as any other in a living cell
or perhaps even more, as !
I also protect them all .
Jeev Jagat Endoplasmic reticulum Ki Adharshila
Nucleus -Endoplasmic reticulum - Golgi apparatus
Magnus manske , P Broks – Wc – cc
3-4 ER & 9-10 Golgi
3 D rendering of Endoplasmic reticulum
Bruce blaus – Wc – cc
Jeev jagat ki Adharshila
ER in a Lung Cell-TEM
Louisa Howard – Wc – cc
Endoplasmic reticulum
A winding network of membranous tubules
continuous with nuclear membrane
and looking like flattened sacs
I am a large organelle spread like folded sheets
adjacent to nucleus in all Eukaryotic cells
A part of me is always studded with
lots of tiny ribosomes giving me
the name of rough endoplasmic reticulum
which processes proteins and transports them.
Jeev jagat ki Adharshila
The other part remains smooth
and plays role in the synthesis
of Lipids and Steroids such as
Cholesterols and hormones.
A specialized part of it is
also Involved in Ca+ storage
and its timely release.
My functionsalso include such duties
as drug detoxification and attachment
of cell membrane proteins.
Transport vesicles keep shuttling
between me and Golgi bodies
targeting mostly new proteins
to their destinations in or out of cells.
Actually I am an important part
of transportation system as well
and ensure timely supply of proteins
and lipids etc to all other organelles.
Jeev jagat ki Adharshila
To my mind it looks like a
longish chemistry lab surely
famous for its role in, mainly
synthesis , folding and tagging
of proteins,
and sending them in vesicles
wherever need be ,
although it carries on merrily
many more functions undoubtedly .
Jeev jagat Cytoskeleton Ki Adharshila
Pulmonary artery –Endothelial cells – fluorescent cells
Cytoskeleton - Wc – Public domain
Actin filaments – Red ; Microtubules - Green ; Nucleus –Blue
Actin microfilaments of Mouse Embryo fibroblasts
T tambe – Wc –cc
Jeev jagat Ki Adharshila
Actin filament
Lydiawc – Wc – cc
Keratin filaments in Embyonal carcinoma cells
Jamie Bush & John Schmidt Wc - cc
Jeev Jagat Ki Adharshila
Microtubule structure
Lydiawc – Wc – cc
Cytoskeleton
I am a Dynamic frame work of Protein filaments
In all living cells many essential functionsI do perform
My main workhorses are three
As Micro filaments , Intermediate filaments
and Micro tubules are known these,
Are made of Actin , Keratin / desmin ,/lamins .,
and Tubulins respectively in eukaryote beings .
Jeev jagat Ki Adharshila
Microfilaments are really thin
two strands of Actin wound in a spiral chain
They aid in cytokinesis , motility , streaming
of cytoplasm , muscle contraction & signaling .
and act as tracks for Myosin motors
moving merrily here & there various vesicles ;
The intermediate filaments are made of
many varieties of proteins
In cytoplasm those of keratins and desmins
maintain cells shape , bear tensions
and provide cell sufficientstructural support .
those of lamin in the Nucleus similarly act as
nuclear envelope’s main support .
The microtubules are hollow contractile tubes of Tubulins
Acting as tracks for Myosin motors
carrying cargo here and there within the cells,
form & function as spindle during cell division
and assist in chromosome segregation ,
provide polarity , attach to cell membrane
and aid in signal transmission .
Jeev jagat Ki Adharshila
Also assist in Endocytosis ;
Play role in synthesis of cell wall
and form Cilia ,&,flagella in some beings.
The most fascinating feature of cytoskeleton
however ,appears to be :
quick disassembly and reassembly
of Actin filaments and Microtubules,
and movement of Myosin motors
on them like a drunkard walking after a spree .
All in all it gives shape , structure and
organization to cytoplasm of the cells
and constantly undergoes remodeling
to fulfill, from time to time, various roles
Besides cytoplasm’s skeleton there is also
Membrane skeleton in a cell playing similar roles
Spectrin is the major player here upholding it
assisting it in some of its functionsand goals.
--------
Life sustaining processes phenomena Jeev jagat ki Adharshila  chapter 3.1  cell organelles  2 copy  ki adharshila

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Life sustaining processes phenomena Jeev jagat ki Adharshila chapter 3.1 cell organelles 2 copy ki adharshila

  • 1. Jeev jagat Om ki Adharshila Diagram of Cell membrane Lady of Hats – Wc – Public domain Nanoscale image of the membrane of a living cell-a bacillus Oak Ridge National Laboratory- Mike Mcrae –Nature-Science alert.com
  • 2. Jeev Jagat poem ki Adharshila Cell membrane They call me cell membrane But I am really Plasma membrane A thin flexible bilayer of amphipathic lipids embedded with a variety of proteins containing all the contents of a cell within my ambit and making a cell look like a baloon filled with fluid in which smaller baloons or capsules of various types were floating freely as if in a pool . That gell like fluid – the cytoplasm Those minuscule bodies – the organelles are my precious possessions & protégé! in my care and protection always. I surround the cell like a fort wall with gates controlling entry & exit of all made possible by my constituents and structure turning me into a unique bio film of one and all
  • 3. Jeev jagat Ki Adharshila My lipid components are mainly three Phospholipids ,Glycolipids and Sterols inbuilt in me but phospholipids with hydrophilic heads and long hydrophobic tails predominate They keep me in liquid crystalline state The Cholesterol stiffens ,strengthens and regulates my fluidity always even when temperature fluctuates. Together all these three are responsible for my main characteristics. My proteins are also mainly three Of Integral ,anchored and peripheral types responsible for many of my features, roles and activities. The integral ones are transmembrane proteins spanning me including protein channels ,proton pumps ,as well as G protein coupled receptors which are major players in signaling and transportation across me.
  • 4. Jeev Jagat ki Adharshila The ion channels allow ions and small molecules to diffuse and also determine my electricalproperties Among the peripheral proteins are some Enzymes and some hormones , which along with anchored G proteins play great role in transmission of signals I am not a semipermeable membrane only but am also involved in many other activities such as cell adhesion ,and ion conductivity, ; And I also act as an attachment for cell wall and carbohydrate calyx on the outer side and the cytoskeleton on the inside, of a cell. And now you tell me Sir Am I not an organelle myself ? or like one and as important as any other in a living cell or perhaps even more, as ! I also protect them all .
  • 5. Jeev Jagat Endoplasmic reticulum Ki Adharshila Nucleus -Endoplasmic reticulum - Golgi apparatus Magnus manske , P Broks – Wc – cc 3-4 ER & 9-10 Golgi 3 D rendering of Endoplasmic reticulum Bruce blaus – Wc – cc
  • 6. Jeev jagat ki Adharshila ER in a Lung Cell-TEM Louisa Howard – Wc – cc Endoplasmic reticulum A winding network of membranous tubules continuous with nuclear membrane and looking like flattened sacs I am a large organelle spread like folded sheets adjacent to nucleus in all Eukaryotic cells A part of me is always studded with lots of tiny ribosomes giving me the name of rough endoplasmic reticulum which processes proteins and transports them.
  • 7. Jeev jagat ki Adharshila The other part remains smooth and plays role in the synthesis of Lipids and Steroids such as Cholesterols and hormones. A specialized part of it is also Involved in Ca+ storage and its timely release. My functionsalso include such duties as drug detoxification and attachment of cell membrane proteins. Transport vesicles keep shuttling between me and Golgi bodies targeting mostly new proteins to their destinations in or out of cells. Actually I am an important part of transportation system as well and ensure timely supply of proteins and lipids etc to all other organelles.
  • 8. Jeev jagat ki Adharshila To my mind it looks like a longish chemistry lab surely famous for its role in, mainly synthesis , folding and tagging of proteins, and sending them in vesicles wherever need be , although it carries on merrily many more functions undoubtedly .
  • 9. Jeev jagat Cytoskeleton Ki Adharshila Pulmonary artery –Endothelial cells – fluorescent cells Cytoskeleton - Wc – Public domain Actin filaments – Red ; Microtubules - Green ; Nucleus –Blue Actin microfilaments of Mouse Embryo fibroblasts T tambe – Wc –cc
  • 10. Jeev jagat Ki Adharshila Actin filament Lydiawc – Wc – cc Keratin filaments in Embyonal carcinoma cells Jamie Bush & John Schmidt Wc - cc
  • 11. Jeev Jagat Ki Adharshila Microtubule structure Lydiawc – Wc – cc Cytoskeleton I am a Dynamic frame work of Protein filaments In all living cells many essential functionsI do perform My main workhorses are three As Micro filaments , Intermediate filaments and Micro tubules are known these, Are made of Actin , Keratin / desmin ,/lamins ., and Tubulins respectively in eukaryote beings .
  • 12. Jeev jagat Ki Adharshila Microfilaments are really thin two strands of Actin wound in a spiral chain They aid in cytokinesis , motility , streaming of cytoplasm , muscle contraction & signaling . and act as tracks for Myosin motors moving merrily here & there various vesicles ; The intermediate filaments are made of many varieties of proteins In cytoplasm those of keratins and desmins maintain cells shape , bear tensions and provide cell sufficientstructural support . those of lamin in the Nucleus similarly act as nuclear envelope’s main support . The microtubules are hollow contractile tubes of Tubulins Acting as tracks for Myosin motors carrying cargo here and there within the cells, form & function as spindle during cell division and assist in chromosome segregation , provide polarity , attach to cell membrane and aid in signal transmission .
  • 13. Jeev jagat Ki Adharshila Also assist in Endocytosis ; Play role in synthesis of cell wall and form Cilia ,&,flagella in some beings. The most fascinating feature of cytoskeleton however ,appears to be : quick disassembly and reassembly of Actin filaments and Microtubules, and movement of Myosin motors on them like a drunkard walking after a spree . All in all it gives shape , structure and organization to cytoplasm of the cells and constantly undergoes remodeling to fulfill, from time to time, various roles Besides cytoplasm’s skeleton there is also Membrane skeleton in a cell playing similar roles Spectrin is the major player here upholding it assisting it in some of its functionsand goals. --------