Potassium iodate is a strong oxidizing agent that can be used to assay several pharmaceutical substances through titration. It reacts quantitatively with both iodides and iodine. The titrations can be performed in the presence of organic acids, alcohols, and other organic substances. The oxidation-reduction reactions with potassium iodate produce iodine monochloride in strong hydrochloric acid. Some applications of potassium iodate titrations include the determination of potassium iodide, weak iodine solutions, aqueous iodine solutions, sodium diatrizoate, iodized oil fuel injection, mercury chloride, and hydralazine hydrochloride and injection.

1. Lecture- 19
Subject – Pharmaceutical Analysis-I
Course – B. Pharm 1st Year
Faculty Name – Umesh Kumar

2. Potassium iodate (KIO3)
 It is regarded to be strong oxidizing agent which may be
employed in the assay of number of pharmaceutical
substances like benzalkonium chloride, phenylhydrazine
hydrochloride, potassium iodide etc.

3. Principle:
 The principle of titrations with potassium iodate (KIO3)
is, the iodate reacts quantitatively with both iodides (I- )
and iodine (I2).
 The respective iodate titrations may be accomplished in
the presence of saturated organic acids, alcohols and
several other organic substances.
 The oxidation-reduction methods with KIO3 is based on
the production of iodine monochloride (ICl) in a
medium of strong HCl.

5. Applications;
1. Potassium iodide(KI)
2. Weak I2 solution
3. Aqueous I2 solution
4. Sodium diatrizoate
5. Iodized oil fuel injection
6. Determination of Hg(HgCl2)
7. Hydralazine HCl and injection IP

7. To be continued in Next video