The document discusses the etiology and causes of malocclusion. It identifies general causes such as evolution, congenital malformations, endocrinal disturbances, and nutritional deficiencies. Local causes include factors like congenitally missing or supernumerary teeth, teeth of abnormal size/form, abnormal eruption path, thumb sucking, premature loss of deciduous teeth, prolonged retention of deciduous teeth, delayed eruption of permanent teeth, loss of permanent teeth, trauma, and local pathological factors like cysts and tumors. The document is a lecture on malocclusion causes presented by Dr. Ahmed Basyouni on March 5, 2012.